Compounds > fingolimod hydrochloride
Page last updated: 2024-09-02

fingolimod hydrochloride and etoposide

fingolimod hydrochloride has been researched along with etoposide in 5 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)		Trials
(fingolimod hydrochloride)		Recent Studies (post-2010)
(fingolimod hydrochloride)		Studies
(etoposide)		Trials
(etoposide)		Recent Studies (post-2010) (etoposide)
2,7711572,06218,3063,6934,900

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)etoposide (IC50)
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]Homo sapiens (human)1.153
nuclear receptor coactivator 3 isoform aHomo sapiens (human)1.4284
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)3.187
Caspase-3Homo sapiens (human)1
DNA topoisomerase 2-betaHomo sapiens (human)0.4299
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)4.18

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Aizu-Yokota, E; Hasegawa, M; Kasahara, T; Momoi, T; Sakurai, S; Sonoda, Y; Yamamoto, D1
Amano, T; Fujino, M; Funeshima, N; Guo, L; Kawasaki, M; Kitazawa, Y; Li, XK; Suzuki, S1
Han, Y; Ma, DH; Wang, ZH; Xing, Y1
Borriello, L; Cherryholmes, G; DeClerck, YA; Lee, H; Li, W; Lifshitz, V; Makovski-Silverstein, A; Priceman, SJ; Yu, H1
Anderson, E; Ekins, S; Foil, DH; Havener, TM; Hickey, AJ; Makarov, V; Monakhova, N; Puhl, AC; Rank, L; Riabova, O; Zorn, KM1

Other Studies

5 other study(ies) available for fingolimod hydrochloride and etoposide

ArticleYear
FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
    Biochemical and biophysical research communications, 2001, Feb-23, Volume: 281, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 6; Caspases; Cell Death; Cell Survival; Cysteine Proteinase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Etoposide; Fingolimod Hydrochloride; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; Immunosuppressive Agents; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Propylene Glycols; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sphingosine; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates

2001
Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells).
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Antibodies; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspases; DNA Fragmentation; Enzyme Activation; Enzyme Activators; Etoposide; fas Receptor; Fingolimod Hydrochloride; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Immunosuppressive Agents; Indicators and Reagents; Jurkat Cells; Propylene Glycols; Sphingosine

2002
FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1.
    Journal of digestive diseases, 2014, Volume: 15, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fingolimod Hydrochloride; Gene Expression; Humans; Immunosuppressive Agents; Propylene Glycols; Sphingosine

2014
Sphingosine-1-Phosphate Receptor-1 Promotes Environment-Mediated and Acquired Chemoresistance.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:11

    Topics: Animals; Apoptosis; Bone Marrow Cells; Drug Resistance, Neoplasm; Etoposide; Fingolimod Hydrochloride; Gene Expression Regulation, Neoplastic; Gene-Environment Interaction; Humans; Mesenchymal Stem Cells; Mice; Neoplasm Recurrence, Local; Neuroblastoma; Receptors, Lysosphingolipid; RNA, Small Interfering; Sphingosine-1-Phosphate Receptors; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2017
Multiple approaches to repurposing drugs for neuroblastoma.
    Bioorganic & medicinal chemistry, 2022, 11-01, Volume: 73

    Topics: Bayes Theorem; Cell Line, Tumor; Child; Child, Preschool; Crizotinib; Drug Repositioning; Etoposide; Fingolimod Hydrochloride; Humans; Neuroblastoma; Niclosamide

2022