fingolimod hydrochloride has been researched along with benzyloxycarbonylleucyl-leucyl-leucine aldehyde in 3 studies
| Studies (fingolimod hydrochloride) | Trials (fingolimod hydrochloride) | Recent Studies (post-2010) (fingolimod hydrochloride) | Studies (benzyloxycarbonylleucyl-leucyl-leucine aldehyde) | Trials (benzyloxycarbonylleucyl-leucyl-leucine aldehyde) | Recent Studies (post-2010) (benzyloxycarbonylleucyl-leucyl-leucine aldehyde) |
|---|---|---|---|---|---|
| 2,771 | 157 | 2,062 | 2,473 | 3 | 1,057 |
| Protein | Taxonomy | fingolimod hydrochloride (IC50) | benzyloxycarbonylleucyl-leucyl-leucine aldehyde (IC50) |
|---|---|---|---|
| Proteasome subunit beta type-11 | Homo sapiens (human) | 1.9893 | |
| Calpain-9 | Homo sapiens (human) | 9.88 | |
| Proteasome subunit alpha type-7 | Homo sapiens (human) | 1.9893 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 3.9 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 3.8999 | |
| Aromatase | Homo sapiens (human) | 0.044 | |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | 0.5 | |
| Proteasome subunit beta type-1 | Homo sapiens (human) | 1.0853 | |
| Proteasome subunit alpha type-1 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit alpha type-2 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit alpha type-3 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit alpha type-4 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-8 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-9 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit alpha type-5 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-4 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-6 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-5 | Homo sapiens (human) | 0.6088 | |
| Proteasome subunit beta type-10 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-3 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-2 | Homo sapiens (human) | 2.0443 | |
| Proteasome subunit alpha type-6 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit alpha-type 8 | Homo sapiens (human) | 1.9893 | |
| Proteasome subunit beta type-7 | Homo sapiens (human) | 1.9893 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Morley, SJ; Pain, VM | 1 |
| Hla, T; Lin, CY; Liu, CH; Lynch, KR; Macdonald, TL; Oo, ML; Thangada, S; Wu, MT | 1 |
| de Seny, D; Deroyer, C; Gillet, P; Malaise, MG; Malaise, O; Plener, Z; Relic, B | 1 |
3 other study(ies) available for fingolimod hydrochloride and benzyloxycarbonylleucyl-leucyl-leucine aldehyde
| Article | Year |
|---|---|
Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines.
Topics: Acetylcysteine; Apoptosis; Calpain; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Eukaryotic Initiation Factor-4G; fas Receptor; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Jurkat Cells; Leupeptins; Multienzyme Complexes; Peptide Fragments; Peptide Initiation Factors; Propylene Glycols; Proteasome Endopeptidase Complex; Sphingosine; T-Lymphocytes | 2001 |
Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor.
Topics: Angiogenesis Inhibitors; Cell Line; Enzyme Inhibitors; Fingolimod Hydrochloride; Green Fluorescent Proteins; Humans; Immunosuppressive Agents; Leupeptins; Ligands; Microscopy, Confocal; Propylene Glycols; Proteasome Endopeptidase Complex; Protein Binding; Receptors, Lysosphingolipid; Sphingosine; Ubiquitin | 2007 |
TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells.
Topics: Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blotting, Western; Cells, Cultured; Cysteine Proteinase Inhibitors; Fibroblasts; Fingolimod Hydrochloride; HEK293 Cells; Humans; Immunosuppressive Agents; Leupeptins; Microscopy, Fluorescence; Mutation; Phosphorylation; Pyrazoles; Pyrimidines; Sequestosome-1 Protein; Serine; Synovial Membrane | 2021 |