Page last updated: 2024-09-02

fingolimod hydrochloride and atropine

fingolimod hydrochloride has been researched along with atropine in 2 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010) (atropine)
2,7711572,06226,7111,2591,697

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)atropine (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)21.41
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.012
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0067
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0007
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0009
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0015
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0021
Alpha-1D adrenergic receptorHomo sapiens (human)1.354
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.012

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hunt, TL; Kovarik, JM; Maton, S; Neddermann, D; Riviere, GJ; Schmouder, RL; Slade, A1
Crump, N; Greene, SL; Kerr, F; Rotella, JA; Stephenson, M; Wong, A1

Trials

1 trial(s) available for fingolimod hydrochloride and atropine

ArticleYear
The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Area Under Curve; Atropine; Circadian Rhythm; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Female; Fingolimod Hydrochloride; Heart Rate; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Middle Aged; Propylene Glycols; Sphingosine; Telemetry; Time Factors; Treatment Outcome

2008

Other Studies

1 other study(ies) available for fingolimod hydrochloride and atropine

ArticleYear
Deliberate fingolimod overdose presenting with delayed hypotension and bradycardia responsive to atropine.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2014, Volume: 10, Issue:2

    Topics: Adult; Antidotes; Atropine; Bradycardia; Combined Modality Therapy; Drug Overdose; Female; Fingolimod Hydrochloride; Humans; Hypotension; Immunosuppressive Agents; Muscarinic Antagonists; Propylene Glycols; Sphingosine; Time Factors; Treatment Outcome

2014