fingolimod has been researched along with sphingosine in 4 studies
| Studies (fingolimod) | Trials (fingolimod) | Recent Studies (post-2010) (fingolimod) | Studies (sphingosine) | Trials (sphingosine) | Recent Studies (post-2010) (sphingosine) |
|---|---|---|---|---|---|
| 65 | 0 | 51 | 8,325 | 117 | 3,459 |
| Protein | Taxonomy | fingolimod (IC50) | sphingosine (IC50) |
|---|---|---|---|
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | 6.3125 | |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | 0.098 | |
| Sphingosine kinase 2 | Homo sapiens (human) | 1.56 | |
| Sphingosine kinase 1 | Homo sapiens (human) | 3.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Billich, A; Charron, G; Guerini, D; Hanessian, S | 1 |
| Don, AS; Martinez-Lamenca, C; Proia, RL; Roberts, E; Rosen, H; Webb, WR | 1 |
| Feng, Y; Mahmood, R; Ni, E; Qin, X; Sun, B; Xie, J; Yang, W; Yue, L; Yue, Z; Zhang, Y | 1 |
| Edinger, AL; Hanessian, S; Kim, SM; McCracken, AN; Nguyen, DG; O'Donoghue, H; Perryman, MS; Rafelski, S; Simitian, GS; Tessier, J; Viana, M; Wiher, T | 1 |
4 other study(ies) available for fingolimod and sphingosine
| Article | Year |
|---|---|
Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors.
Topics: Animals; Aza Compounds; Calcium; Cell Line; CHO Cells; Chromatography, Thin Layer; Cricetinae; Cricetulus; Cytoplasm; Drug Design; Fingolimod Hydrochloride; Humans; Immunologic Factors; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Probes; Phosphorylation; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine | 2007 |
Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.
Topics: Animals; Apoptosis; Autoimmune Diseases; bcl-2-Associated X Protein; Calcium Signaling; Caspases; Cell Membrane Permeability; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Fingolimod Hydrochloride; HeLa Cells; Humans; Immunosuppressive Agents; Jurkat Cells; Lymphoproliferative Disorders; Mice; Mice, Knockout; Mitochondria; Mutagenesis; Organ Specificity; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Protein Transport; Receptors, Lysosphingolipid; Sphingolipids; Sphingosine; Spleen; Thymus Gland | 2007 |
Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels.
Topics: Animals; Cells, Cultured; Fingolimod Hydrochloride; HEK293 Cells; Humans; Immunosuppressive Agents; Membrane Potentials; Membrane Transport Modulators; Mice; Myocytes, Cardiac; Organophosphates; Phosphorylation; Propylene Glycols; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Recombinant Proteins; Sphingosine; TRPM Cation Channels | 2013 |
Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death.
Topics: Animals; Cell Death; Down-Regulation; Humans; Hydrocarbons; Membrane Transport Proteins; Sphingolipids; Stereoisomerism; Structure-Activity Relationship; Vacuoles | 2016 |