finasteride and nadp

finasteride has been researched along with nadp in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chen, C; Labire F [corrected to Labrie, F]; Labrie, F; Li, X; Singh, SM1
Andersson, S; Azzolina, B; Bull, HG; Ellsworth, K; Geissler, W; Harris, GS1
Sun, ZY; Tu, ZH1
Ahmed, S; Denison, S1
Christianson, DW; Di Costanzo, L; Drury, JE; Penning, TM1
Shamsara, J1
Fan, H; Huang, J; Liu, H; Shen, T; Supekar, S; Wang, L; Wei, Z; Xiao, Q; Ye, F; Zhang, C1

Reviews

1 review(s) available for finasteride and nadp

ArticleYear
The enzyme and inhibitors of 4-ene-3-oxosteroid 5 alpha-oxidoreductase.
    Steroids, 1995, Volume: 60, Issue:6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Azasteroids; Dihydrotestosterone; Finasteride; NADP; Quinolones; Steroids; Structure-Activity Relationship

1995

Other Studies

6 other study(ies) available for finasteride and nadp

ArticleYear
Inhibition of rat alpha-reductases by finasteride: evidence for isozyme differences in the mechanism of inhibition.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:1-2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; COS Cells; Enzyme Inhibitors; Finasteride; Hot Temperature; Isoenzymes; Kinetics; NADP; Protein Denaturation; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins

1997
A novel in vitro model to screen steroid 5 alpha-reductase inhibitors against benign prostatic hyperplasia.
    Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Animals; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Finasteride; Kinetics; Male; Microsomes, Liver; NADP; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Spectrophotometry

1998
Mechanism based representation of the active site of 5 alpha-reductase (5AR).
    Bioorganic & medicinal chemistry letters, 1998, Sep-22, Volume: 8, Issue:18

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Azasteroids; Binding Sites; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Models, Chemical; Models, Molecular; NADP; Pregnanes; Structure-Activity Relationship; Testosterone

1998
Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex.
    The Journal of biological chemistry, 2009, Jul-24, Volume: 284, Issue:30

    Topics: Binding, Competitive; Crystallography, X-Ray; Enzyme Inhibitors; Finasteride; Humans; Male; Models, Molecular; Molecular Structure; NADP; Oxidoreductases; Progesterone; Prostatic Hyperplasia; Protein Binding; Protein Conformation; Testosterone

2009
Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data.
    Interdisciplinary sciences, computational life sciences, 2019, Volume: 11, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Catalytic Domain; Computer Simulation; Drug Discovery; Finasteride; Humans; Models, Chemical; Molecular Dynamics Simulation; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation

2019
Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride.
    Nature communications, 2020, 10-27, Volume: 11, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Amino Acid Motifs; Androgen Antagonists; Dutasteride; Finasteride; Humans; Membrane Proteins; Molecular Dynamics Simulation; NADP

2020
chemdatabank.com