finasteride and mk 386
finasteride has been researched along with mk 386 in 11 studies
Research
Studies (11)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chavez, CM; Constanzer, ML; De Lepeleire, I; De Schepper, PJ; Ebel, DL; Gertz, BJ; Justice, SJ; Lasseter, KC; Schwartz, JI; Shamblen, EC; Van Hecken, A; Wang, DZ; Winchell, GA | 1 |
| Dallob, A; Ebel, DL; Geissler, LA; Gertz, BJ; Hafkin, B; Schwartz, JI; Tanaka, WK; Wang, DZ | 1 |
| Altenburger, R; Kissel, T | 1 |
| Bidlingmaier, F; Hans, VH; Heidrich, DD; Klingmüller, D; Schramm, J; Steckelbroeck, S; Stoffel-Wagner, B | 1 |
| Bühler, H; Halis, G; Hundertmark, S; Kuhlmann, K; Ragosch, V; Weitzel, HK | 1 |
| Bidlingmaier, F; Hans, VH; Heidrich, DD; Klingmüller, D; Reichelt, R; Schramm, J; Steckelbroeck, S; Stoffel-Wagner, B; Watzka, M | 1 |
| Angelucci, A; Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Vicentini, C | 1 |
| Fritsch, M; Seiffert, K; Seltmann, H; Zouboulis, CC | 1 |
| Liu, S; Yamauchi, H | 1 |
| Angelucci, A; Bologna, M; Festuccia, C; Gravina, GL; Muzi, P; Pomante, R; Vicentini, C | 1 |
| Bühler, P; Elsässer-Beile, U; Fischer, T; Gierschner, D; Schultze-Seemann, W; Wetterauer, U; Wolf, P | 1 |
Trials
2 trial(s) available for finasteride and mk 386
| Article | Year |
|---|---|
Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men.
Topics: Adult; Azasteroids; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Double-Blind Method; Drug Synergism; Finasteride; Humans; Male; Osmolar Concentration; Oxidoreductases | 1996 |
MK-386, an inhibitor of 5alpha-reductase type 1, reduces dihydrotestosterone concentrations in serum and sebum without affecting dihydrotestosterone concentrations in semen.
Topics: 5-alpha Reductase Inhibitors; Adolescent; Adult; Androstane-3,17-diol; Azasteroids; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Luteinizing Hormone; Male; Middle Aged; Sebum; Semen; Testosterone | 1997 |
Other Studies
9 other study(ies) available for finasteride and mk 386
| Article | Year |
|---|---|
The human keratinocyte cell line HaCaT: an in vitro cell culture model for keratinocyte testosterone metabolism.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Administration, Cutaneous; Androstenedione; Antineoplastic Agents, Hormonal; Azasteroids; Cell Culture Techniques; Cell Line; Enzyme Inhibitors; Fibroblasts; Finasteride; Humans; Hydrogen-Ion Concentration; Keratinocytes; Skin; Testosterone; Tritium | 1999 |
Characterization of aromatase cytochrome P450 activity in the human temporal lobe.
Topics: Adolescent; Adult; Age Factors; Androstenedione; Aromatase; Azasteroids; Child; Dose-Response Relationship, Drug; Female; Finasteride; Humans; Kinetics; Male; Middle Aged; Organ Specificity; Placenta; Sex Factors; Temporal Lobe | 1999 |
Kinetic studies on rabbit liver glucocorticoid 5alpha-reductase.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Azasteroids; Corticosterone; Enzyme Inhibitors; Finasteride; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Kinetics; Liver; Rabbits | 2000 |
Characterization of the 5alpha-reductase-3alpha-hydroxysteroid dehydrogenase complex in the human brain.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adolescent; Adult; Aged; Azasteroids; Brain; Child; Child, Preschool; Enzyme Inhibitors; Epilepsy; Female; Finasteride; Humans; Hydrogen-Ion Concentration; Infant; Isoenzymes; Male; Microsomes; Middle Aged; Neocortex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; Temporal Lobe; Tissue Distribution | 2001 |
Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells.
Topics: 5-alpha Reductase Inhibitors; Aged; Androgens; Antineoplastic Agents, Hormonal; Azasteroids; Cell Line, Tumor; Cell Proliferation; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Humans; Male; Neoplasm Staging; Prostatic Hyperplasia; Prostatic Neoplasms | 2005 |
Inhibition of 5alpha-reductase activity in SZ95 sebocytes and HaCaT keratinocytes in vitro.
Topics: Androgen Receptor Antagonists; Androgens; Azasteroids; Cell Proliferation; Cells, Cultured; Cholestenone 5 alpha-Reductase; Finasteride; Humans; Keratinocytes; Protein Biosynthesis; Sebaceous Glands; Testosterone | 2007 |
Different patterns of 5alpha-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Azasteroids; Cells, Cultured; Cholestenone 5 alpha-Reductase; Face; Finasteride; Hair Follicle; Humans; Isoenzymes; Male; Reverse Transcriptase Polymerase Chain Reaction; Scalp | 2008 |
Effects of dutasteride on prostate carcinoma primary cultures: a comparative study with finasteride and MK386.
Topics: 5-alpha Reductase Inhibitors; Aged; Azasteroids; Cell Proliferation; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Tumor Cells, Cultured | 2008 |
Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors.
Topics: Anilides; Antineoplastic Agents; Azasteroids; Cell Differentiation; Cell Line, Tumor; Cholestenone 5 alpha-Reductase; Enzyme Inhibitors; Finasteride; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; Tosyl Compounds | 2010 |