fiduxosin has been researched along with pyrimidinones in 6 studies
| Studies (fiduxosin) | Trials (fiduxosin) | Recent Studies (post-2010) (fiduxosin) | Studies (pyrimidinones) | Trials (pyrimidinones) | Recent Studies (post-2010) (pyrimidinones) |
|---|---|---|---|---|---|
| 14 | 3 | 5 | 6,059 | 604 | 2,692 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brune, ME; Buckner, SA; Esbenshade, TA; Hancock, AA; Ireland, LM; Katwala, S; Kerwin, JF; Meyer, MD; Milicic, I; Williams, M | 1 |
| Brune, ME; Hancock, AA; Katwala, SP; Kerwin, JF; Meyer, MD; Milicic, I; Williams, M; Witte, DG | 1 |
| Brune, ME; Hancock, AA; Hui, YH; Katwala, SP; Kerwin, JF; Marsh, KC; Meyer, MD; Milicic, I; Stolarik, D; Witte, DG | 1 |
| Daszkowski, DJ; Dutta, S; Granneman, GR; Verlinden, M; Zhang, Y | 2 |
| Colanesi, S; Ishizaki, H; Kelsh, RN; Liu, D; Lundegaard, PR; North, TE; Patton, EE; Taylor, KL; Temperley, ND | 1 |
2 trial(s) available for fiduxosin and pyrimidinones
| Article | Year |
|---|---|
Multiple dose pharmacokinetics of fiduxosin under fasting conditions in healthy elderly male subjects.
Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adrenergic Antagonists; Aged; Area Under Curve; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Fasting; Heterocyclic Compounds, 3-Ring; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pyrimidinones; Receptors, Adrenergic, alpha-1 | 2002 |
Single- and multiple-dose pharmacokinetics of fiduxosin under nonfasting conditions in healthy male subjects.
Topics: Administration, Oral; Aged; Area Under Curve; Dietary Fats; Dose-Response Relationship, Drug; Fasting; Feces; Food-Drug Interactions; Health; Heterocyclic Compounds, 3-Ring; Humans; Male; Middle Aged; Pyrimidinones | 2002 |
4 other study(ies) available for fiduxosin and pyrimidinones
| Article | Year |
|---|---|
Preclinical pharmacology of fiduxosin, a novel alpha(1)-adrenoceptor antagonist with uroselective properties.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Heterocyclic Compounds, 3-Ring; Humans; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Prostatic Hyperplasia; Pyrimidinones; Rabbits; Radioligand Assay; Rats; Rats, Inbred SHR; Urethra; Urinary Tract; Urodynamics; Vas Deferens | 2002 |
Effect of fiduxosin, an antagonist selective for alpha(1A)- and alpha(1D)-adrenoceptors, on intraurethral and arterial pressure responses in conscious dogs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heterocyclic Compounds, 3-Ring; Male; Phenylephrine; Prazosin; Prostate; Pyrimidinones; Regional Blood Flow; Sulfonamides; Tamsulosin; Urethra | 2002 |
Modeling of relationships between pharmacokinetics and blockade of agonist-induced elevation of intraurethral pressure and mean arterial pressure in conscious dogs treated with alpha(1)-adrenoceptor antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Area Under Curve; Blood Pressure; Dogs; Half-Life; Heterocyclic Compounds, 3-Ring; Male; Models, Biological; Phenylephrine; Pyrimidinones; Regional Blood Flow; Urethra | 2002 |
Small molecule screening identifies targetable zebrafish pigmentation pathways.
Topics: Animals; Cell Count; Chromatophores; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Heterocyclic Compounds, 3-Ring; Melanocytes; Metabolic Networks and Pathways; Phenotype; Pigmentation; Purines; Pyrimidinones; Roscovitine; Small Molecule Libraries; Tyrphostins; Zebrafish | 2012 |