fidarestat has been researched along with fr 74366 in 2 studies
| Studies (fidarestat) | Trials (fidarestat) | Recent Studies (post-2010) (fidarestat) | Studies (fr 74366) | Trials (fr 74366) | Recent Studies (post-2010) (fr 74366) |
|---|---|---|---|---|---|
| 97 | 3 | 33 | 48 | 2 | 7 |
| Protein | Taxonomy | fidarestat (IC50) | fr 74366 (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.0044 | |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | 6.6027 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 2.0005 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Degliesposti, G; Ferrari, AM; Rastelli, G; Sgobba, M | 1 |
| Kato, N; Oka, M | 1 |
1 review(s) available for fidarestat and fr 74366
| Article | Year |
|---|---|
Aldose reductase inhibitors.
Topics: Aldehyde Reductase; Binding Sites; Clinical Trials as Topic; Crystallography, X-Ray; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imidazoles; Imidazolidines; Naphthalenes; Quinazolines | 2001 |
1 other study(ies) available for fidarestat and fr 74366
| Article | Year |
|---|---|
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors.
Topics: Aldehyde Reductase; Binding Sites; Binding, Competitive; Computer Simulation; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Inhibitory Concentration 50; Models, Biological; Molecular Structure; Thermodynamics | 2007 |