Page last updated: 2024-09-04

fidarestat and dinoprostone

fidarestat has been researched along with dinoprostone in 2 studies

Compound Research Comparison

Studies
(fidarestat)
Trials
(fidarestat)
Recent Studies (post-2010)
(fidarestat)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
9733329,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomyfidarestat (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ramana, KV; Saxena, A; Srivastava, SK; Tammali, R1
Ramana, KV; Shoeb, M; Srivastava, SK; Yadav, UC1

Other Studies

2 other study(ies) available for fidarestat and dinoprostone

ArticleYear
Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.
    The Journal of biological chemistry, 2011, Jul-08, Volume: 286, Issue:27

    Topics: Aldehyde Reductase; Caco-2 Cells; Cell Hypoxia; Colonic Neoplasms; Cyclooxygenase 2; Cysteine Proteinase Inhibitors; Dinoprostone; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazolidines; Leupeptins; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein-Lysine 6-Oxidase; Proto-Oncogene Proteins c-akt; RNA, Messenger; RNA, Neoplasm; Vascular Endothelial Growth Factor A; Vimentin

2011
Amelioration of experimental autoimmune uveoretinitis by aldose reductase inhibition in Lewis rats.
    Investigative ophthalmology & visual science, 2011, Oct-11, Volume: 52, Issue:11

    Topics: Aldehyde Reductase; Animals; Aqueous Humor; Autoimmune Diseases; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Eye Proteins; Fluorescent Antibody Technique, Indirect; Imidazolidines; Lymphocyte Activation; Male; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Retinitis; Retinol-Binding Proteins; T-Lymphocytes; Uveitis

2011