Compounds > fidarestat
Page last updated: 2024-09-04

fidarestat and D-fructopyranose

fidarestat has been researched along with D-fructopyranose in 7 studies

Compound Research Comparison

Studies
(fidarestat)		Trials
(fidarestat)		Recent Studies (post-2010)
(fidarestat)		Studies
(D-fructopyranose)		Trials
(D-fructopyranose)		Recent Studies (post-2010) (D-fructopyranose)
9733318,0951,0415,633

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kato, N; Makino, M; Mizuno, K; Suzuki, T; Yagihashi, S1
Amano, S; Hirooka, H; Inagaki, Y; Jomori, T; Kato, N; Makino, M; Okamoto, T; Takeuchi, M; Taniko, K; Yamagishi, Si1
Abatan, OI; Frank, RN; Kumagai, AK; Minchenko, AG; Obrosova, IG; Stevens, MJ; Vasupuram, R; White, L1
Hirooka, H; Obrosova, IG; Pacher, P; Stevens, MJ; Szabó, C; Yorek, MA; Zsengeller, Z1
Hattori, T; Matsubara, A; Ogura, Y; Taniguchi, K1
Agardh, CD; Agardh, E; El-Remessy, AB; Maksimchyk, Y; Obrosova, IG; Pacher, P; Smith, ML1
Hirooka, H; Nadler, JL; Obrosova, IG; Shevalye, H; Stavniichuk, R1

Other Studies

7 other study(ies) available for fidarestat and D-fructopyranose

ArticleYear
Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats.
    Diabetes research and clinical practice, 2000, Volume: 50, Issue:2

    Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Fructose; Glycated Hemoglobin; Imidazoles; Imidazolidines; Inositol; Male; Myelin Sheath; Nerve Fibers; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sorbitol; Sural Nerve; Tibial Nerve; Time Factors

2000
Sorbitol dehydrogenase overexpression potentiates glucose toxicity to cultured retinal pericytes.
    Biochemical and biophysical research communications, 2002, Nov-29, Volume: 299, Issue:2

    Topics: Aldehyde Reductase; Animals; Blood-Retinal Barrier; Capillary Permeability; Cattle; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA; Endothelial Growth Factors; Enzyme Inhibitors; Fructose; Glucose; Imidazoles; Imidazolidines; Intercellular Signaling Peptides and Proteins; L-Iditol 2-Dehydrogenase; Lymphokines; Male; Pericytes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retina; RNA, Messenger; Sorbitol; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.
    Diabetes, 2003, Volume: 52, Issue:3

    Topics: Aldehyde Reductase; Angiogenesis Inducing Agents; Animals; Cattle; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Flow Cytometry; Fructose; Gene Expression; Glucose; Glutathione; Glutathione Peroxidase; Imidazoles; Imidazolidines; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Retina; Retinal Vessels; RNA, Messenger; Sorbitol; Superoxide Dismutase; Vascular Endothelial Growth Factor A

2003
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.
    Diabetes, 2005, Volume: 54, Issue:1

    Topics: Aldehyde Reductase; Animals; Aorta; Arterioles; Cattle; Diabetes Mellitus, Experimental; Endothelium, Vascular; Fructose; Imidazolidines; Male; Motor Neurons; Neural Conduction; Neurons, Afferent; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Sciatic Nerve; Sorbitol; Tyrosine

2005
Aldose reductase inhibitor fidarestat attenuates leukocyte-endothelial interactions in experimental diabetic rat retina in vivo.
    Current eye research, 2010, Volume: 35, Issue:2

    Topics: Acridine Orange; Administration, Oral; Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Fluorophotometry; Fructose; Imidazolidines; Intercellular Adhesion Molecule-1; Leukocytes; Male; Microscopy, Fluorescence; Rats; Rats, Long-Evans; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sorbitol; Vascular Endothelial Growth Factor A

2010
Evaluation of the aldose reductase inhibitor fidarestat on ischemia-reperfusion injury in rat retina.
    International journal of molecular medicine, 2010, Volume: 26, Issue:1

    Topics: Aldehyde Reductase; Animals; Apoptosis; Blotting, Western; Drug Evaluation, Preclinical; Female; Fructose; Glucose; Imidazolidines; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intravenous; L-Iditol 2-Dehydrogenase; Rats; Rats, Wistar; Reperfusion Injury; Retina; Sorbitol

2010
Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy.
    Biochemical pharmacology, 2012, Apr-01, Volume: 83, Issue:7

    Topics: Aldehyde Reductase; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Blood Glucose; Blotting, Western; Calcium; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme-Linked Immunosorbent Assay; Fructose; Ganglia, Spinal; Imidazolidines; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Sciatic Nerve; Sorbitol; Spinal Cord; Streptozocin

2012