fexofenadine has been researched along with terfenadine in 616 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 45 (7.31) | 18.2507 |
| 2000's | 318 (51.62) | 29.6817 |
| 2010's | 213 (34.58) | 24.3611 |
| 2020's | 40 (6.49) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S | 1 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Chen, XL; Hendrix, J; Kang, J; Korolev, AM; Lysenkova, LN; Miroshnikova, OV; Pearlstein, RA; Preobrazhenskaya, M; Rampe, D; Shchekotikhin, AE; Vaz, RJ | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Eddy, P; Goldman, E; Huang, W; Jia, ZJ; Kadambi, V; Scarborough, RM; Sinha, U; Song, Y; Su, T; Tumas, D; Zhang, P; Zhu, BY | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Imai, YN; Oiki, S; Ryu, S | 1 |
| Aslanian, R; Du, XY; Hey, JA; McLeod, RL; Piwinski, JJ; Priestley, T; Sorota, S; West, RE; Williams, SM; Zhang, XS; Zhu, X | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Abu Khalaf, R; Abu Sheikha, G; Bustanji, Y; Taha, MO | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Hitchcock, SA | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, JL; Chen, X; Dai, K; Fan, P; Fu, Y; Jaen, J; Li, L; Liang, L; Lindstrom, M; Mihalic, JT; Motani, A; Tang, L | 1 |
| Colquhoun, JM; Dunman, PM; Ebsworth-Mojica, K; Flaherty, DP; Forbes, LT; Krysan, DJ; Perlmutter, JI; Wang, JL | 1 |
| Rankovic, Z | 1 |
| Coutant, JE; Nardella, PA; Okerholm, RA; Walter, SM; Westmark, PA | 1 |
| Blaschke, G; Terhechte, A | 1 |
| Ido, T; Ito, K; Itoh, M; Iwata, R; Ryu, JH; Sawai, Y; Watanabe, T; Yanai, K | 1 |
| Bergman, JN; Simons, FE; Simons, KJ; Watson, WT | 1 |
| Nightingale, SL | 1 |
| Ashworth, L | 1 |
| Arumugham, T; Bhargava, V; Eller, M; Lippert, C; Stoltz, M; Weir, S; Yu, D | 1 |
| Paul, E | 1 |
| Merk, HF | 1 |
| Ahlbrandt, R; Bernstein, DI; Mason, J; Nathan, RA; Schoenwetter, WF; Storms, W | 1 |
| Simons, FE; Simons, KJ | 1 |
| Briscoe, MP; Clark, A; Day, JH; Ellis, AK; Mason, J; Smith, JN; Welsh, A | 1 |
| Markham, A; Wagstaff, AJ | 1 |
| O'Hanlon, JF; Vermeeren, A | 1 |
| Abdelaziz, MM; Bayram, H; Davies, RJ; Devalia, JL; Khair, OA; Prior, AJ | 1 |
| Estes, KS; González, MA | 2 |
| Olson, SC; Smithers, JA; Stern, RH | 1 |
| Bhargava, VO; Castles, MA; Pack, DJ; Robbins, DK; Weir, SJ | 1 |
| Russell, T; Stoltz, M; Weir, S | 1 |
| Bagnasco, M; Battifora, M; Bertolini, C; Bloom, M; Canonica, GW; Ciprandi, G; Cutolo, M; Paolieri, F; Riccio, AM | 1 |
| Christian, S; Jensen, M; Kind, P; Ricard, N; Stewart, J | 1 |
| Philpot, E | 1 |
| Ahlbrandt, R; Mason, J; Pratt, CM; Reynolds, R; Russell, T | 1 |
| Mattila, MJ; Paakkari, I | 1 |
| Fellrath, JM; Rahm, F; Spertini, F; Terrien, MH | 1 |
| Giraud, T | 1 |
| Compton, D; Mason, J; Ricard, N; Stewart, J; Sussman, GL | 1 |
| Fairweather, DB; Hindmarch, I; Shamsi, Z; Stanley, N | 1 |
| Cvetkovic, M; Fromm, MF; Kim, RB; Leake, B; Wilkinson, GR | 1 |
| Danielson, L; DeVos, C; Grant, JA; Rihoux, JP | 1 |
| Mason, J; Rao, N; Reynolds, R | 1 |
| Ahlbrandt, R; Brown, AM; Mason, J; Pratt, C; Rampe, D; Reynolds, R; Russell, T | 1 |
| Crijns, HJ; Heeringa, M; Pinto, YM; van Gelder, IC | 1 |
| Kendall, MJ; Po, AL | 1 |
| Shuster, J | 1 |
| Casale, TB; Meltzer, EO; Nathan, RA; Thompson, AK | 1 |
| Bousquet, J; Howarth, PH; Reynolds, R; Roi, L; Stern, MA | 1 |
| Finn, AF; Fretwell, R; Kaplan, AP; Long, J; Qu, R | 1 |
| Coletta, D; Di Giacomo, B; Natalini, B; Ni, MH; Pellicciari, R | 1 |
| Kashyap, AS; Kashyap, S | 1 |
| Mills, SL; Nicholson, AN; Stone, BM; Turner, C | 1 |
| Baker, TW; Bloomfield, JR; Brown, TL; Grant, AR; Layton, TA; McKenzie, DR; Watson, GS; Weiler, JM; Woodworth, GG | 1 |
| Hennessy, S; Strom, BL | 1 |
| Jarvis, B; Simpson, K | 1 |
| Craig-McFeely, PM; Freemantle, SL; Pearce, GL; Shakir, SA | 1 |
| Dunn, N; Mann, RD; Pearce, GL; Shakir, S | 1 |
| Mason, J; Nelson, HS; Reynolds, R | 1 |
| Abdelaziz, MM; Devalia, JL; Khair, OA | 1 |
| Hari, Y; Müller, U; Reimers, A | 1 |
| Dhar, S; Hazra, PK; Malakar, S; Mistri, G | 1 |
| Juniper, EF; Van Cauwenberge, P | 1 |
| Finn, AF; Schoenwetter, WF; Thompson, AK | 1 |
| Amon, S; Amon, U; Gibbs, BF | 1 |
| Irman-Florjanc, T | 1 |
| Capano, D; Harris, AG; Prenner, BM | 1 |
| Benedetto, SR; Duncan, BS; Sloan, AS | 1 |
| Brookhuis, KA; de Waard, D | 1 |
| Demonaco, HJ; Dudley, J; Lee, TH | 1 |
| Angello, JT; Druce, HM | 1 |
| Shaikh, WA | 1 |
| Bazex, J; Journé, F; Loche, E; Marguery, MC; Schwarze, HP | 1 |
| D'Oronzio, L; Dambra, P; Ferrannini, A; Loria, MP; Nettis, E; Tursi, A | 1 |
| Gu, X; Johnston, L; Simons, FE; Simons, KJ | 1 |
| Gu, X; Silver, NA; Simons, FE; Simons, KJ | 2 |
| Bruce, MA; Haehner-Daniels, BD; Hall, SD; Hamman, MA | 1 |
| Dagenais, C; Ducharme, J; Pollack, GM | 1 |
| Bunnag, C; Chochaipanichnon, L; Jareoncharsri, P; Kongpatanakul, S; Limprasertsiri, S; Pumhirun, P; Supiyaphun, P; Tunsuriyawong, P | 1 |
| Amichai, B; Brenner, L; Grunwald, MH | 1 |
| Bastlund, J; Evans, AM; Jørgensen, KL; Larsen, LA; Milne, RW; Stretch, GR | 1 |
| Affrime, M; Banfield, C; Batra, V; Clement, R; Gupta, S; Kantesaria, B; Marino, M | 1 |
| Aunhachoke, K; Charuwichitratana, S; Gherunpong, N; Gritiyarangsan, P; Janjumratsang, P; Jiamton, S; Korkij, W; Krisadapong, J; Kullavanijaya, P; Kulthanan, K; Kuntiranont, M; Sitakalin, C | 1 |
| Duvernelle, C; Frossard, N; Melac, M; Pauli, G; Purohit, A | 1 |
| Anderson, SD; Brannan, JD; Chan, HK; Gomes, K; King, GG; Seale, JP | 1 |
| Burtin, B; De Vos, C; Donnelly, F; Horak, F; Kavina, A; Stübner, P; Zieglmayer, R | 1 |
| Cummins, G; Lee, J; Okamoto, L | 1 |
| Bernstein, DI; Goldsobel, A; Graft, DF; Long, J; Meltzer, EO; Portnoy, J | 1 |
| Choo, EF; Dresser, GK; Kim, RB; Kubba, SV; Lan, LB; Leake, BF; McKinsey, J; Schuetz, EG; Schuetz, JD; Schwarz, UI; Taylor, A; Wilkinson, GR; Xie, HG; Zhou, S | 1 |
| Benko, LB | 1 |
| Acharya, NV; Craig-McFeely, PM; Shakir, SA | 1 |
| Górska, M; Grzelewska-Rzymowska, I; Pietrzkowicz, M | 1 |
| Cummins, G; Leahy, M; Liao, E | 1 |
| Canonica, GW; Ciprandi, G; Cosentino, C; Milanese, M; Mondino, C | 1 |
| Asghar, A; Gorski, JC; Haehner-Daniels, B; Hall, SD | 1 |
| Bailey, DG; Dawson, PA; Dresser, GK; Freeman, DJ; Kim, RB; Leake, BF; Schwarz, UI | 1 |
| Drescher, S; Fromm, MF; Hofmann, U; Seiler, M | 1 |
| DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM | 1 |
| Wilson, AM | 1 |
| Affrime, M; Banfield, C; Gupta, S; Lim, J; Marino, M | 1 |
| Fridliand, DG; Gushchin, IS; Poroshina, IuA; Shul'zhenko, AE | 1 |
| Brinkmann, U; Drescher, S; Eichelbaum, M; Fromm, MF; Hitzl, M; Hofmann, U; Schaeffeler, E; Schwab, M | 1 |
| Coutie, WJ; Lipworth, BJ; Orr, LC; Sims, EJ; Wilson, AM | 1 |
| Hindmarch, I; Kimber, S; Shamsi, Z | 1 |
| Bircher, A; Degonda, M; Helbling, A; Pichler, WJ | 1 |
| Bensch, GW; Borish, LC; Nelson, HS | 1 |
| Anderson, CL; Anson, BD; January, CT; Rajamani, S | 1 |
| Abbasi, AA; Dempsey, JA; Haverkamp, HC; Meyer, KC; Rice, AJ; Sonetti, DA; Wetter, TJ; Xiang, Z | 1 |
| Stein, CM | 1 |
| Hall, SD; Hamman, MA; Huang, SM; Lesko, LJ; Wang, Z | 1 |
| Om Reddy, G; Radhakrishna, T | 1 |
| Cui, ZH; Gelfand, EW; Joetham, A; Kanehiro, A; Takeda, K | 2 |
| Chowdhury, BA | 1 |
| Berkowitz, RB; Lutz, C; Meeves, S; Moss, M; Weiler, J; Weiler, K; Woodworth, GG | 1 |
| Abelson, MB; Berger, WE; D'Arienzo, PA; Granet, DB; Kägi, MK; Lanier, BQ; Spangler, DL | 1 |
| Cassano, N; Coviello, C; D'Argento, V; Filieri, M; Filotico, R; Vena, G | 1 |
| Addison, T; Jiang, X; Maleki, S; Naidong, W; Shou, WZ | 1 |
| Haggart, K; Lipworth, BJ; Sims, EJ; Wilson, AM | 1 |
| Harada, S; Kawashima, M; Tango, T | 1 |
| Koop, A; Mösges, R | 1 |
| Busch, AE; Decher, N; Dennis, AT; Ficker, E; Lerche, C; Maier, P; Scherer, CR; Steinmeyer, K; Wollnik, B | 1 |
| Greenblatt, DJ; Perloff, MD; von Moltke, LL | 1 |
| Harvey, P; Meeves, SG; Miura, Y; Mohler, SR; Nicholson, A | 1 |
| Inoue, T; Katoh, N; Kishimoto, S; Matsunaga, K | 1 |
| Itoh, M; Iwabuchi, K; Mochizuki, H; Sakurada, Y; Tashiro, M; Watanabe, T; Yanai, K | 1 |
| Abraham, D; Saltoun, CA | 1 |
| Allocco, FT; Baroody, FM; deTineo, M; Naclerio, RM; Votypka, V | 1 |
| Akbay, E; Apa, DD; Cayan, S | 1 |
| Kinoshita, H; Koizuka, I; Kuroda, H; Miyabe, S; Ochi, K; Sugiyama, Y; Takatsu, M; Tanaka, K | 1 |
| Dresser, GK; Kim, RB; Schwarz, UI; Wilkinson, GR | 1 |
| Cheung, BS; Heskin, R; Hofer, KD | 1 |
| Chee, P; Lum, G; Sojo, LE | 1 |
| Knutson, L; Knutson, T; Lennernäs, H; Tannergren, C | 1 |
| Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ | 1 |
| Austin, M; Bower, EA; Meeves, S; Moore, JL; Moss, M; Selby, KA | 1 |
| Jackson, CM; Lee, DK; Lipworth, BJ | 2 |
| de Vries, HJ; Kammeyer, A; Mekkes, JR | 1 |
| Bachert, C; Baena-Cagnani, C; Decosta, P; Finn, AF; Hedlin, G; Kowalski, ML; Meltzer, EO; Potter, P; Rosado Pinto, JE; Ruuth, E; Scheinmann, P; Simons, FE; Wahn, U | 1 |
| Grzelewska-Rzymowska, I; Kroczyńska-Bednarek, J; Pietrzkowicz, M | 1 |
| Hindmarch, I; Ridout, F | 1 |
| Hagan, LL; More, DR; Napoli, DC | 1 |
| Flores, J; Mansfield, L; Meeves, SG; Mendoza, C | 1 |
| Boyce, M; Carey, W; Luria, X; Warrington, S | 1 |
| Alexander, M; Allegro, S; Hicks, A; Patel, P | 1 |
| Goritz, SS; J Semus, M; Simons, FE; Simons, KJ | 1 |
| Duchateau, J; Heenen, M; Sternon, J | 1 |
| Harada, S; Inagi, M; Kawashima, M; Nakagawa, H; Noguchi, T; Tango, T | 1 |
| Christian, CD; Crisalida, T; Economides, A; Georges, GC; Hale, M; Kaliner, MA; Liao, Y; Meeves, SG; White, MV; Woodworth, TH | 1 |
| Hindmarch, I; Johnson, S; Meadows, R; Ridout, F; Shamsi, Z | 1 |
| Glass, DJ; Harper, AS | 1 |
| Casale, T; Chervinsky, P; Fowler-Taylor, A; Fox, H; Hedgecock, S; Shen, H; Townley, R; Tripathy, I | 1 |
| Potter, PC; Schepers, JM; Van Niekerk, CH | 1 |
| Abelson, MB; Gotnes, PJ; Ober, A; Spangler, DL | 1 |
| Grzelewska-Rzymowska, I | 1 |
| Appajosyula, S; Meeves, SG | 1 |
| Canonica, GW; Ciprandi, G; Cosentino, C; Passalacqua, G; Riccio, AM; Tosca, MA | 1 |
| Portnoy, JM; Simon, SD | 1 |
| Georges, G; Hampel, F; Liao, Y; Mansfield, L; Meeves, S; Ratner, P | 1 |
| Bondesson, U; Hedeland, M; Knutson, L; Lennernäs, H; Petri, N; Tannergren, C | 1 |
| Antonijoan, RM; Barbanoj, MJ; Esbrí, R; Garcia, E; García-Gea, C; Gich, I; Gispert, J; Luria, X; Morte, A | 1 |
| Dicpinigaitis, PV; Gayle, YE | 1 |
| Furue, M; Morita, K; Moroi, Y; Nakahara, T; Urabe, K | 1 |
| Hasegawa, Y; Hindmarch, I; Ishikawa, K; Kamei, H; Muraoka, I; Nabeshima, T; Noda, Y; Senzaki, K | 1 |
| Appajosyula, S; Gelfand, EW; Meeves, S | 1 |
| Dogra, S; Handa, S; Kumar, B | 1 |
| Baroody, FM; deTineo, M; Maleckar, B; Moinuddin, R; Naclerio, RM | 1 |
| Asano, K; Kanai, K; Suzaki, H | 2 |
| Masuda, A; Matsuda, E; Nariai, K; Shibasaki, T; Watanabe, N | 1 |
| Glass, D; Harper, A | 1 |
| Haggart, K; Jackson, CM; Lee, DK; Lipworth, BJ | 1 |
| Fujihara, S; Gray, RD; Lee, DK; Lipworth, BJ; Robb, FM | 1 |
| Fujihara, S; Gardiner, M; Haggart, K; Lee, DK; Lipworth, BJ | 1 |
| Adesanya, H | 1 |
| Sugawara, K; Takahata, T; Tateishi, T; Uno, T; Yasui-Furukori, N; Yoshiya, G | 1 |
| Fardon, TC; Jackson, CM; Lee, DK; Lipworth, BJ; Soutar, PC | 1 |
| Ciprandi, G; Cirillo, I; Vizzaccaro, A | 1 |
| Fu, I; Matuszewski, BK; Woolf, EJ | 1 |
| Sugawara, K; Takahata, T; Tateishi, T; Uno, T; Yasui-Furukori, N | 1 |
| Bachert, C; Finn, AF; Hedlin, G; Meltzer, EO; Rosado Pinto, JE; Ruuth, E; Scheinmann, P; Wahn, U | 1 |
| Fooanant, S; Roongapinun, S; Wajajamreon, S | 1 |
| Przybilla, B; Ruëff, F | 1 |
| Aoki, M; Funaki, Y; Itoh, M; Iwabuchi, K; Iwata, R; Kato, M; Mochizuki, H; Sakurada, Y; Tashiro, M; Wong, DF; Yanai, K | 1 |
| Benedetti, MS; Diquet, B; Molimard, M | 1 |
| Leahy, MJ; Lennox, RD | 1 |
| Berger, WE; Corren, J; LaForce, CF; Wheeler, WJ | 1 |
| Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Abbas, MN; Abdel Fattah, AA; Zahran, E | 1 |
| Lennernäs, H; Petri, N; Rungstad, D; Tannergren, C | 1 |
| Buisson, D; Jaouen, M; Mazier, C; Sari, MA | 1 |
| Jensen, BK; Kittner, B; Krishna, R; Krishnaswami, S; Sankoh, AJ | 1 |
| Cho, JY; Chung, JY; Hong, KS; Jang, IJ; Jung, HR; Kim, JR; Lim, HS; Oh, DS; Shin, SG; Yi, SY; Yu, KS | 1 |
| Chong, S; Kamath, AV; Yao, M; Zhang, Y | 1 |
| Hoffer, C; Kharasch, ED; Sheffels, P; Walker, A | 1 |
| Deslandes, B; Frossard, N; N'Gom, AS; Pauli, G; Purohit, A | 1 |
| Halliwill, JR; Lockwood, JM; Wilkins, BW | 1 |
| Sugawara, K; Tateishi, T; Uno, T; Yasui-Furukori, N | 1 |
| Crawford, B; Gotoh, M; Okubo, K; Okuda, M; Ritsu, M; Shimada, K | 1 |
| Asano, K; Kanai, KI; Suzaki, H | 1 |
| Antal, EJ; Arakawa, T; Gordi, T; Hong, C; Knuth, DW; Nickens, DJ; Polasek, EC; Sharma, A; Tan, LH; Teillol-Foo, M; Xie, R | 1 |
| Bailey, DG; Dresser, GK; Kim, RB | 1 |
| Kobayashi, M; Tokura, Y | 1 |
| Fuse, E; Kusuhara, H; Sugiyama, Y; Tahara, H | 1 |
| Eichelbaum, M; Fromm, MF; Hofmann, U; Kivistö, KT; Niemi, M; Schwab, M | 1 |
| Fujieda, S; Hyo, S; Kawada, R; Kitazawa, S; Takenaka, H | 1 |
| Harding, G; Leahy, M; Lennox, RD; Shikiar, R | 1 |
| Horak, F; Kavina, A; Lemell, P; Zieglmayer, PU; Zieglmayer, R | 1 |
| Agrawala, P; Haribhakti, R; Howard, DR; Kittner, B | 1 |
| Georges, G; Kaplan, AP; Liao, Y; Meeves, S; Spector, SL; Varghese, ST | 1 |
| Fuse, K; Kusuhara, H; Maeda, K; Nishigaki, R; Okudaira, K; Shimizu, M; Sugiyama, Y | 1 |
| Makita, S; Sakairi, T; Shakuto, S; Suzuki, K; Wajima, T; Yaguchi, M; Yoshida, Y | 1 |
| Conboy-Ellis, K | 1 |
| Cha, IJ; Choi, YG; Hong, WS; Lee, SS; Nguyen, PM; Shin, JG; Shon, JH; Yoon, YR | 1 |
| Hindmarch, I; Horikawa, E; Inokuchi, T; Kato, M; Mochizuki, H; Ridout, F; Sakurada, Y; Tashiro, M; Yanai, K | 1 |
| Chung, SJ; Kim, DD; Lee, MK; Lin, H; Roh, HJ; Shim, CK; Yoo, JW | 1 |
| Gotoh, Y; Kamada, N; Momose, D | 1 |
| Dhar, S; Georges, G; Varghese, ST | 1 |
| Breier, AR; Paim, CS; Schapoval, EE; Steppe, M | 1 |
| Jonkman, LM; Kuypers, KP; Ramaekers, JG; Theunissen, EL | 1 |
| Boyle, J; Hindmarch, I; Johnsen, S; Meadows, R; Ridout, F | 1 |
| Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ | 1 |
| Havránek, E; Mikus, P; Valásková, I | 1 |
| Darlath, W; Gillissen, A; Juergens, UR; Racké, K; Stober, M; Tasci, S; Vetter, H | 1 |
| Baltes, E; Benedetti, MS; Chatelain, P; Gillard, M | 1 |
| Green, GR | 1 |
| Ciebiada, M; Górska-Ciebiada, M; Górski, P; Grzelewska-Rzymowska, I; Zakrzewska, A | 1 |
| Goldberg, I; Tessler, L | 1 |
| Izu, K; Tokura, Y | 1 |
| Fujita, H; Ikezawa, Z; Inomata, N; Kanbara, T; Osuna, H | 1 |
| Fuse, E; Koepsell, H; Kusuhara, H; Maeda, K; Sugiyama, Y; Tahara, H | 1 |
| Fukuda, H; Kamikozawa, Y; Ohashi, R; Sugiura, M; Tamai, I; Yabuuchi, H | 1 |
| Berkowitz, RB; Braker, S; Georges, G; Jones, P; Lutz, C; Meeves, S; Qiu, C; Varghese, ST | 1 |
| Bondesson, U; Borga, O; Hedeland, M; Lennernas, H; Nyberg, L; Petri, N | 1 |
| Gorski, JC; Hall, SD; Hamman, MA; Lemma, GL; Wang, Z; Zaheer, NA | 1 |
| Bondesson, U; Broström, H; Ingvast-Larsson, C; Larsson, P; Olsén, L; Sundqvist, M; Tjälve, H | 1 |
| Arakawa, S; Fujiwara, S; Hatano, Y; Katagiri, K | 1 |
| Direkwattanachai, C; Ngamphaiboon, J; Tiensuwan, M; Vangveeravong, M; Visitsunthorn, N | 1 |
| Bergman, E; Bondesson, U; Forsell, P; Hedeland, M; Knutson, L; Lennernäs, H; Petri, N | 1 |
| Mansfield, LE | 2 |
| Shimizu, M; Sugawara, K; Tateishi, T; Uno, T | 3 |
| Murata, K; Nakai, Y; Ohashi, Y | 1 |
| Saraswat, A; Saraswat, M | 1 |
| Brouwer, KL; Hoffmaster, KA; Kalvass, JC; Pollack, GM; Turncliff, RZ | 1 |
| Blom-Coenjaerts, C; Ramaekers, JG; Theunissen, EL; van Deursen, JA; van Kroonenburgh, MJ | 1 |
| Berisa, A; Corcóstegui, R; Innerárity, A; Labeaga, L; Orjales, A | 1 |
| Brunton, S; Spangler, DL | 1 |
| Bourbeau, M; Cameron, DW; Campbell, P; Chauhan, BM; Foster, BC; Seguin, I; van Heeswijk, RP | 1 |
| Boyle, J; Eriksson, M; Fujita, T; Kumagi, Y; Stanley, N | 1 |
| Burtin, B; Hohlfeld, JM; Krug, N; Larbig, M; Luettig, B; Martin, L; Stamm, H | 1 |
| Cousineau, M; Danser, E; Dewire, R; Floden, J; Peng, SX; Ritchie, DM | 1 |
| Davey, AK; Ngo, SN; Tong, Y; Zhang, R | 1 |
| Elad, S; Heisler, S; Shalit, M | 1 |
| Miura, M; Suzuki, T; Tateishi, T; Uno, T | 3 |
| Kamei, J; Takahashi, Y | 1 |
| Hahn, EG; Müller, S; Raithel, M; Weidenhiller, M; Winterkamp, S | 1 |
| Cohen, AD; Gan-El, U; Lieberman, N; Reuvni, H; Vardy, DA | 1 |
| Kikuchi, A; Maeda, T; Nozawa, T; Tamai, I; Wakasawa, T | 1 |
| Magen, E; Mishal, J; Viskoper, RJ; Yosefy, C | 1 |
| Kandikere, VN; Komarneni, P; Maurya, S; Mudigonda, K; Nirogi, RV; Shukla, M | 2 |
| Bian, S; Chung, SJ; Gebhardt, M; Kim, DD; Kwon, KA; Lin, H; Shim, CK | 1 |
| Darlath, W; Gillissen, A; Juergens, UR; Racké, K; Stöber, M; Uen, S; Vetter, H | 1 |
| Couderc, JP | 1 |
| Cinca, J; Farré, J; Hove-Madsen, L; Llach, A; Molina, CE; Prat-Vidal, C; Roura, S | 1 |
| Camelo-Nunes, IC | 1 |
| Kazama, E; Kume, T; Ogasawara, A | 1 |
| Bazelmans, D; Berkowitz, RB; Georges, G; Godfrey, P; Liao, Y; Lutz, C; McCafferty, F; Meeves, S | 1 |
| Chegini, S; Hamilos, DL; Oren, E | 1 |
| Blaiss, MS; Lehman, JM | 1 |
| Bailey, DG; Dresser, GK; Glaeser, H; Gregor, JC; Jolicoeur, E; Kim, RB; Leake, BF; Lee, W; McGrath, JS; Schwarz, UI; Tirona, RG | 1 |
| Codreanu, A; de Chillou, C; Moneret-Vautrin, DA | 1 |
| Bailey, DG; Dresser, GK; Kim, RB; Leake, BF | 1 |
| Aragane, Y; Ashenager, MS; Grgela, T; Kawada, A | 1 |
| Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K | 1 |
| Oliveira, DC; Rolim, CM; Weigch, A | 1 |
| Kruszewski, J; Kłos, K; Sułek, K | 1 |
| Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K | 1 |
| Harding, G; Leahy, MJ; Meeves, S; Shikiar, R; Spector, SL | 1 |
| Abusuev, SA; Gadzhimirzaev, GA; Gamzatova, AA; Gamzatova, EG | 1 |
| Marshman, G; Pellizzari, M | 1 |
| Begany, P; Dyrhonova, M; Emritte, N; Mendoza, L; Svobodova, X | 1 |
| Castellano, PM; Kaufman, TS; Maggio, RM; Vignaduzzo, SE | 1 |
| Chen, C | 1 |
| Kumagai, Y; Sugiyama, Y; Tanimoto, T; Tozuka, Z; Yamane, N; Yamazaki, A | 1 |
| Nemes, P; Vertes, A | 1 |
| Asano, K; Furuta, A; Furuya, A; Hisamitsu, T; Kanai, K; Suzaki, H | 1 |
| Bridges, AS; Brouwer, KL; Li, J; Nezasa, K; Patel, NJ; Raub, TJ; Tian, X; Zamek-Gliszczynski, MJ | 1 |
| Hampel, FC; Kittner, B; Lanier, R; Milgrom, H | 1 |
| Kabashima, K; Sugita, K; Tokura, Y | 1 |
| Hayashi, S; Itabashi, T; Kamei, J; Kawai, K; Takahashi, Y | 1 |
| Breier, AR; Nudelman, NS; Schapoval, EE; Steppe, M | 1 |
| Benhamou, AH; Eigenmann, PA; Lantin, JP; Vanini, G | 1 |
| Herzinger, T; Maier, T | 1 |
| Karakuş, S; Küçükgüzel, I; Küçükgüzel, SG | 1 |
| Badwan, AA; Davies, D; Eric, J; Omari, MM; Zughul, MB | 1 |
| Inui, S; Itami, S; Nakajima, T | 1 |
| Igarashi, T; Ishiguro, N; Maeda, K; Matsushima, S; Sugiyama, Y | 1 |
| Alfaro, RM; Davey, RT; Formentini, E; Penzak, SR; Robertson, SM; Voell, J | 1 |
| Hampel, FC; Kittner, B; van Bavel, JH | 1 |
| Debori, Y; Hayashi, H; Kusuhara, H; Maeda, K; Matsushima, S; Schinkel, AH; Schuetz, JD; Sugiyama, Y | 1 |
| Belinsky, MG; Brouwer, KL; Kruh, GD; Swift, B; Tian, X; Zamek-Gliszczynski, MJ | 1 |
| Kawabata, T; Kitamura, Y; Koto, H; Kusuhara, H; Matsuura, S; Sugiyama, Y; Tsuchiya, H; Tsujimoto, H | 1 |
| Morita, E; Takahashi, H; Zhang, Y | 1 |
| Devillier, P; Faisy, C; Roche, N | 1 |
| Boev, R; De Vos, C; Derde, MP; Mitchev, K; Pinelli, ME | 1 |
| Beringer, PM; Burckart, GJ; Hidayat, L; Liu, S; Louie, S; Rao, AP; Shapiro, B | 1 |
| Casale, TB; Jones, DH; Romero, FA | 1 |
| Ahn, JH; Kim, JE; Kim, MJ; Kim, SD; Lee, HW; Moon, SO; Park, DJ; Yoon, YR | 1 |
| Kobayashi, M; Oda, M; Saitoh, H; Ujie, K | 1 |
| Kumar, AR; Musmade, P; Pathak, SM; Udupa, N | 1 |
| Fukui, H; Izumi, N; Mizuguchi, H; Ogino, S; Umehara, H | 1 |
| Enatsu, K; Kumagami, H; Takahashi, H; Takasaki, K | 1 |
| Crawley, G; Moore, J; Rice, GM; Vacchiano, C | 1 |
| Davis, CB; Dawson, PA; Garver, E; Han, C; Hugger, ED; Rao, A; Shearn, SP | 1 |
| Borzova, E; Grattan, CE; Konstantinou, GN; Leslie, KS; Rutherford, A | 1 |
| Brun, ME; Funk, C; Grimm, HP; Kansy, M; Lavé, T; Poirier, A; Portmann, R; Senner, F | 1 |
| Halliwill, JR; Lynn, BM; McCord, JL; Pellinger, TK | 1 |
| Deshmukh, SV; Durston, J; Shomer, NH | 1 |
| Horita, S; Inoue, K; Kondo, T; Kusuhara, H; Maeda, K; Matsushima, S; Nakayama, H; Ohta, KY; Sugiyama, Y; Yuasa, H | 1 |
| Bridges, AS; Kalvass, JC; Pollack, GM; Yanni, SB; Zhao, R | 1 |
| Kim, KA; Park, JY; Park, PW | 1 |
| Bedynek, PS; Hoffer, C; Kharasch, ED; Walker, A; Whittington, D | 1 |
| Akiyama, K; Dobashi, H; Ishida, T; Karaki, M; Kobayshi, R; Mori, N | 1 |
| Ikezawa, Z; Inomata, N; Tatewaki, S | 1 |
| Chen, J; Crossman, L; Hsieh, Y; Knemeyer, I; Korfmacher, WA | 1 |
| Chupka, J; Feng, B; Fenner, KS; Frederick, KS; Kalgutkar, AS; Kempshall, S; Mireles, RJ; Troutman, MD | 1 |
| Fukuda, T; Kashima, R; Okada, T; Sagara, H; Yukawa, T | 1 |
| Han, HK; Lee, BJ; Lee, W; Qiang, F | 1 |
| Brouwer, KL; Swift, B; Tian, X | 1 |
| Inui, S; Itami, S; Nakajima, T; Toda, N | 1 |
| Homann, J; Kolck, UW; Molderings, GJ; Schröder, D; Solleder, G; von Kügelgen, I; Vorreuther, R | 1 |
| Bachert, C | 1 |
| Gums, JG; Smith, SM | 1 |
| Hokama, N; Miura, M; Sakugawa, T; Suzuki, T; Tateishi, T; Uno, T | 1 |
| dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A | 1 |
| Fan, H; Guo, D; Lou, S; Qin, Q; Zhu, Y; Zou, J | 1 |
| Cheng, L; Dake, Y; Enomoto, K; Enomoto, T; Ide, T; Lu, HQ; Sakoda, T; Yin, M | 1 |
| Cao, Z; Jie, J; Li, W; Zhang, R; Zhou, Y | 1 |
| Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH | 1 |
| Frye, RF; Himmelfarb, J; Le, P; Leblond, FA; Naud, J; Nolin, TD; Pichette, V; Sadr, H | 1 |
| Milne, RW; Ngo, SN; Turkanovic, J | 1 |
| Barghi, L; Islambulchilar, Z; Jalilian, H; Valizadeh, H; Zakeri-Milani, P | 1 |
| Elvira, Jde L; Ramaekers, JG; Theunissen, EL; van den Bergh, D | 1 |
| Abdullah, VJ; Au, CT; Chan, IH; Chan, MH; Lam, CW; Lam, HS; Leung, AW; Li, AM; Ng, PC; So, HK; Tsen, CS | 1 |
| Kimoto, N; Tamura, T | 1 |
| Akamine, Y; Kaneko, S; Uno, T; Yamada, S; Yasui-Furukori, N | 1 |
| Imai, T; Ninomiya, S; Ohura, K; Sakamoto, H | 1 |
| Horak, F; Lemell, P; Zieglmayer, P; Zieglmayer, R | 1 |
| Moeller, ML; Nahata, MC; Phan, H | 1 |
| Miura, M; Uno, T | 1 |
| Frye, RF; Joy, MS; Stanton, ML | 1 |
| Eguchi, H; Kogure, Y; Komatsubara, K; Matsuhisa, T; Miyoshi, K | 1 |
| Shaikh, SW; Shaikh, WA | 1 |
| Ewert, R; Gläser, S; Gustavus, B; Hanf, G; Koch, B; Kunkel, G; Noga, O; Schäper, C | 1 |
| Cho, HJ; Choi, MK; Chung, SJ; Huh, Y; Kim, DD; Kim, JS; Oh, E; Shim, CK; Yoon, IS | 1 |
| Chodorowska, G; Dybiec, E; Jastrzebska, I; Juszkiewicz-Borowiec, M; Krasowska, D; Maciejewski, R; Pietrzak, A; Schwartz, RA | 1 |
| Beale, KK; Bertino, JS; Ma, JD; Nafziger, AN; Trivedi, M; Tsunoda, SM | 1 |
| Lehmacher, W; Mösges, R; Pasch, N; Vent, J | 1 |
| Kim, KA; Park, JY | 1 |
| Bjerrum, OJ; Garner, C; Gesson, C; Houston, B; Jochemsen, R; Lappin, G; Oosterhuis, B; Rowland, M; Shishikura, Y; Weaver, RJ | 1 |
| Fujita, T; Kumagai, Y; Maeda, M; Sugiyama, Y; Tozuka, Z; Yamane, N; Yamazaki, A; Yokota, S | 1 |
| Han, HK; Jin, MJ | 1 |
| Amin, PD; Jain, SP; Mehta, DC; Shah, SP; Singh, PP | 1 |
| Balakrishnan, P; Cho, HJ; Chung, SJ; Kim, DD; Kim, H; Kim, YS; Piao, HM; Shim, CK | 1 |
| Burggraaff, JE; de Waart, DR; Elferink, RP; Kenworthy, KE; Schinkel, AH; van de Steeg, E; van der Kruijssen, CM; Wagenaar, E | 1 |
| Cingi, C; Gage-White, L; Gunhan, K; Unlu, H | 1 |
| Balakrishnan, P; Cho, HJ; Chung, SJ; Hong, SS; Jang, TY; Kim, DD; Kim, KS; Park, EK; Shim, CK; Song, KW | 1 |
| Ho, HO; Kao, YH; Lin, YK; Liou, YB; Sheu, MT | 1 |
| Ai, H; Gu, Y; Hao, G; Li, Y; Peng, Y; Sun, J; Wang, G; Wu, X; Zhang, J; Zhang, X; Zheng, Y; Zhou, F | 1 |
| Akamine, Y; Kagaya, H; Miura, M; Sunagawa, S; Uno, T; Yasui-Furukori, N | 1 |
| Davey, AK; Gerber, JP; Jaisue, S | 1 |
| Fricker, G; MacLean, C; Moenning, U; Reichel, A | 1 |
| Hosoi, Y; Kanamaru, T; Konno, T; Nakagami, H; Tajiri, S; Yada, S; Yoshida, K | 1 |
| Bailey, DG | 1 |
| Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H | 1 |
| Imai, H; Imanaga, J; Kotegawa, T; Ohashi, K; Ohyama, T; Shirasaka, Y; Tamai, I; Tateishi, T; Tsutsumi, K; Yoshizato, T | 1 |
| Funakushi, N; Ikeda, S; Imamura, S; Jiang, J; Kase, Y; Kobayashi, H; Kuhara, T; Ogawa, H; Suto, H; Ueki, R; Yamaguchi, T | 1 |
| Laguna Martínez, JJ; Reaño Martos, M; Rojas Pérez-Ezquerra, P; Sánchez Morillas, L; Sanz, ML | 1 |
| Alnouti, Y; Gor, P; Reed, GA | 1 |
| Kasurka, CB; Sekeroğlu, V; Sekeroğlu, ZA | 1 |
| Chiyoda, T; Doi, Y; Hirota, T; Ieiri, I; Irie, S; Iwasaki, K; Kimura, M; Maeda, K; Miyagawa, M; Sasaki, T; Sugiyama, Y | 1 |
| Alfaro, RM; Chairez, C; Hunt, JD; Kovacs, JA; Malati, CY; Penzak, SR; Robertson, SM | 1 |
| Behrens, CJ; Caliskan, G; Fano, S; Heinemann, U | 1 |
| Alnouti, Y; Flynn, CA; Reed, GA | 1 |
| Knight, BM; Ming, X; Thakker, DR | 1 |
| Ohkawa, T; Tanaka, Y; Yasui, H | 1 |
| Bermejo, M; Gonzalez-Alvarez, I; Gundogdu, E; Karasulu, E; Mangas-Sanjuan, V | 1 |
| Colyer, CL; el-Hay, SS; Hassan, WS; Shalaby, A | 1 |
| Alvarez, IG; Gundogdu, E; Karasulu, E | 1 |
| Akamine, Y; Kojima, M; Miura, M; Uno, T; Yasui-Furukori, N | 1 |
| Kataoka, M; Masaoka, Y; Sakuma, S; Yamashita, S; Yokoyama, T | 1 |
| Badellino, H; Baena-Cagnani, CE; Baena-Cagnani, R; Braido, F; Canonica, GW; Compalati, E; Gómez, RM; Penagos, M | 1 |
| Bermejo Sanz, M; Gonzalez Alvarez, I; Gundogdu, E; Karasulu, E | 1 |
| Bason, C; Eikel, D; Henion, JD; Korfmacher, WA; Smith, S; Vavrek, M; Yeh, S | 1 |
| Alexander, N; Dahlke, M; Hanna, I; Hariry, S; Jarugula, V; Rebello, S; Vapurcuyan, A; Zhao, S | 1 |
| Isaji, A; Ishikawa, K; Kamei, H; Nabeshima, T; Noda, Y; Senzaki, K; Sugiura, K; Tomita, Y; Yamada, K | 1 |
| Crowe, A; Wright, C | 1 |
| Ito, E; Masuyama, K; Matsuoka, T; Matsuzaki, Z; Nakayama, T; Okamoto, A; Takahashi, G | 1 |
| Allan, RJ; Casale, TB; Hackman, F; Misfeldt, J; Phillips, PG; Romero, FA; Stokes, JR | 1 |
| Constantinescu, C; Gripeos, D; Lilja, Y; Mercolini, L; Mukherjee, J; Ozdemir, V; Raggi, MA; Reist, C; Wu, JC | 1 |
| Fukui, H; Hattori, M; Kitamura, Y; Kuroda, W; Mizuguchi, H; Ogishi, H; Takeda, N | 1 |
| Codreanu, I; Dasanu, CA; Divgi, C; Weinstein, GS | 1 |
| Fukuoka, M; Ikoma, A; Kabashima, K; Miyachi, Y; Tanizaki, H | 1 |
| Levitt, J; Phelps, R; Wong, J | 1 |
| Srinivas, NR; Yao, M | 1 |
| Akamine, Y; Kaneko, S; Niioka, T; Saruwatari, J; Takashima, A; Uno, T; Yasui-Furukori, N | 1 |
| Ali, SM; Crowyn, G; Khan, S | 1 |
| Han, HK; Lee, BJ; Qiang, F; Shin, HJ | 1 |
| Fukuda, K; Horie, T; Shitara, Y; Suzuki, K | 1 |
| Kabashima, K; Miyachi, Y; Nonomura, Y; Otsuka, A | 1 |
| Adachi, Y; Imai, T; Ninomiya, S; Nogata, R; Ohura, K; Soejima, T | 1 |
| Kanda, T; Takizawa, F; Tamura, T; Yamada, K | 1 |
| Tanaka, Y; Yasui, H; Yoshikawa, Y | 1 |
| Asano, K; Furuta, A; Kanai, K; Kanei, A; Nogaki, T; Suzaki, H; Suzaki, I | 1 |
| Barrett-O'Keefe, Z; Halliwill, JR; Kaplon, RE | 1 |
| Banba, H; Takayama, K; Takeda-Morishita, M; Tomaru, A | 1 |
| Church, MK; Maurer, M | 1 |
| Dhaneshwar, S; Gautam, H | 1 |
| Akamine, Y; Fukizawa, S; Ikejiri, K; Kanamitsu, K; Kusuhara, H; Miura, M; Sugiyama, Y; Uno, T; Yasui-Furukori, N; Yokochi, M; Yoshida, K | 1 |
| Church, MK; Maurer, M; Schoepke, N | 1 |
| Chono, S; Hayasaka, M; Morimoto, K; Tada, H; Togami, K; Tosaki, Y | 1 |
| Mori, T; Murata, Y; Nakanishi, T; Shichiri, M; Shirasaka, Y; Tamai, I | 1 |
| Ando, Y; Deguchi, M; Hirota, T; Ieiri, I; Irie, S; Izumi, N; Kanda, E; Kimura, M; Kotani, N; Kusuhara, H; Maeda, K; Matsuguma, K; Matsuki, S; Morishita, M; Okuzono, T; Sugiyama, Y; Tsunemitsu, S; Yamane, N | 1 |
| Ruan, Z; Ye, Z; Zeng, S; Zhou, Q | 1 |
| Guzman, Y | 1 |
| Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H | 1 |
| Fahmy, RM; Hoag, SW; Jancsik, B; Kona, R; Mattes, R; Qu, H | 1 |
| Anoopkumar-Dukie, S; Grant, GD; Kavanagh, JJ; Naicker, P | 1 |
| Hashimoto, T; Konno, Y; Matsuda, Y; Nagai, M; Satsukawa, M; Taguchi, T; Yamashita, S | 1 |
| Bandari, S; Eedara, BB; Jukanti, R; Veerareddy, PR | 1 |
| Ragab, MA; Youssef, RM | 1 |
| Bekkali, N; Boeckxstaens, GE; de Jonge, WJ; Shi, J; Stanisor, OI; van den Wijngaard, RM; van Diest, SA; Welting, O; Yu, Z | 1 |
| Dawson, PA; Lan, T; Oberlies, NH; Paine, MF; Scarlett, YV; Vandermolen, KM; Widmer, WW; Won, CS | 1 |
| Aydogan, M; Aydogmus, CY; Bulan, K; Siraneci, R | 1 |
| Brouwer, KL; Dooley, MA; Falk, RJ; Frye, RF; Joy, MS; La, MK; Nolin, TD; Roberts, BV; Wang, J | 1 |
| Al-Azzam, SI; Alzoubi, KH; Khabour, OF; Mayyas, F | 1 |
| Bondesson, U; Hedeland, M; Lennernäs, H; Sjögren, E | 1 |
| Atia, NN; El-Gizawy, SM; El-Kommos, ME; Hosny, NM | 1 |
| Hisatomi, M; Koba, S; Misago, N; Narisawa, Y; Ono, M | 1 |
| Chu, YH; Lai, WS; Lin, YY; Wang, CH; Wang, HW | 1 |
| Tamai, I | 1 |
| Bosilkovska, M; Daali, Y; Déglon, J; Desmeules, J; Samer, C; Staub, C; Walder, B | 1 |
| Guttikar, S; Kamarajan, K; Mullangi, R; Muppavarapu, R; Rajappan, M | 1 |
| El-Ridi, MS; El-Sherif, NG; Tadros, MI; Yehia, SA | 1 |
| Katayama, I; Kato, K; Kitaba, S; Matsui, S; Murota, H; Suma, A; Takahashi, A; Yamaoka, T; Yokomi, A | 1 |
| Mori, T; Murata, Y; Nakanishi, T; Shirasaka, Y; Tamai, I | 1 |
| Fabre, D; Khier, S; Martinez, JM; Morita, S; Rauch, C | 1 |
| Plichta, D; Spiewak, R | 1 |
| Bosilkovska, M; Daali, Y; Dayer, P; Déglon, J; Desmeules, JA; Rebsamen, M; Samer, CF; Staub, C; Walder, B | 1 |
| Qu, BX; Yao, QQ; Zeng, S; Zhou, Q | 1 |
| Cherian, R; Csanaky, IL; Dileepan, KN; Flynn, CA; Kassel, KM; Klaassen, CD; Lickteig, AL; Luyendyk, JP; Pratt-Hyatt, MJ; Raveendran, VV; Reed, GA; Smith, DD; Williams, KJ | 1 |
| Akamine, Y; Ieiri, I; Komori, H; Kusuhara, H; Miura, M; Saito, S; Tamai, I; Uno, T; Yasui-Furukori, N | 1 |
| Dileepan, KN; Flynn, CA; Milne, G; Raveendran, VV; Reed, GA; Smith, DD; Sweeney, ME; Tan, X; Tawfik, OW | 1 |
| Iranshahi, M; Parhiz, H; Rezaee, R; Roohbakhsh, A; Soltani, F | 1 |
| Ono, A; Sugano, K | 1 |
| Dalla Costa, T; de Andrade, FP; de Castro, WV; de Faria, AC; Júnior, MA; Velozo, Eda S | 1 |
| Chen, YA; Hsu, KY | 1 |
| Akamine, Y; Ieiri, I; Miura, M; Uno, T; Yasui-Furukori, N | 1 |
| Chwen, CC | 1 |
| Chen, M; Chen, W; Chen, X; Guo, A; He, Y; Li, J; Liu, Z; Su, J; Wen, S; Yan, S; Zhang, C; Zhang, J; Zhao, Y; Zhou, H; Zhu, W | 1 |
| Nezasa, K; Ogawa, K; Shimizu, R; Takai, N; Tanaka, Y; Watanabe, A; Watari, R; Yamaguchi, Y | 1 |
| Asher, LJ; Feere, DA; House, AA; Knauer, MJ; Nolin, TD; Thomson, BK; Urquhart, BL; Velenosi, TJ | 1 |
| Grobosch, T; Hiraoka, K; Ishii, K; Ishiwata, K; Maurer, M; Oda, K; Tashiro, M; Toyohara, J; Yanai, K | 1 |
| Chun, J; Kim, BG; Kim, JS; Kim, JW; Koh, SJ; Lee, KL | 1 |
| Kabashima, K; Miyachi, Y; Nakamizo, S; Otsuka, A; Tanizaki, H; Yamamoto, Y | 1 |
| Amarasena, N; Gunawardena, MD; Herath, J; Weerasinghe, A | 1 |
| Brüning, J; Schmidt, MU | 1 |
| Chernykh, IV; Iakusheva, EN; Kotliarova, AA; Nikiforov, AA; Shchul'kin, AV | 1 |
| Bedada, SK; Neerati, P | 1 |
| Balakrishnan, P; Cho, HJ; Hahn, TW; Ko, HJ; Park, EK; Song, CK; Song, KW | 1 |
| Akamine, Y | 1 |
| Banba, H; Kumagai, Y; Kusuhara, H; Maeda, K; Sugiyama, Y; Takayama, K; Takeda-Morishita, M; Tomaru, A | 1 |
| Chen, Y; Jiang, S; Li, F; Li, Y; Liu, L; Liu, X; Xu, P; Zhang, M; Zhao, K; Zhao, W; Zhong, Z | 1 |
| Dahlgren, D; Lennernäs, H; Roos, C; Sjögren, E | 1 |
| Imai, T; Kotani, S; Nakada, Y; Ohura, K | 1 |
| Cieślińska, A; Jarmołowska, B; Karolina Kordulewska, N; Kostyra, E; Matysiewicz, M | 1 |
| Enk, CD; Levi, A | 1 |
| Hashimoto, T; Satoh, T | 1 |
| Fox, EM; Hübner, MP; Mitre, E; Morris, CP | 1 |
| Akamine, Y; Ieiri, I; Komori, H; Miura, M; Tamai, I; Uno, T; Yasui-Furukori, N | 1 |
| Ariyoshi, S; Imai, T; Nakada, Y; Ohura, K; Sawada, T | 1 |
| Srinivas, NR | 2 |
| Feng, L; Li, B; Lv, L; Shi, Y; Yan, M; Zhang, K | 1 |
| El Bedaiwy, HM; Helmy, SA | 1 |
| Arakawa, H; Kanagawa, M; Ogihara, T; Otsuka, K; Tomono, T; Yano, K | 1 |
| Khan, MA; Manzoor, S; Salam, FA; Shoaib, MH; Sultan, F; Yousuf, RI | 1 |
| Hayashi, M; Hirohata, A; Katayama, I; Murota, H; Tani, M; Yamaoka, T | 1 |
| Bedada, SK; Neerati, P; Yellu, NR | 1 |
| Abe, R; Arinami, H; Hama, N; Maruyama, R; Shimomura, Y | 1 |
| Borowska, E; Bourgin, M; Hollender, J; Kienle, C; McArdell, CS; von Gunten, U | 1 |
| Grobosch, T; Hiraoka, K; Inami, A; Komamura, H; Matsuda, R; Maurer, M; Miyake, M; Takeda, K; Tashiro, M; Yamada, Y; Yanai, K | 1 |
| Bosilkovska, M; Daali, Y; Déglon, J; Desmeules, J; Samer, C; Thomas, A; Walder, B | 1 |
| Claro da Silva, T; Gubler, C; Ismair, MG; Jetter, A; Kullak-Ublick, GA; Spanaus, K | 1 |
| Dreyer, HC; Ely, MR; Halliwill, JR; Hocker, AD; Luttrell, MJ; Mangum, JE; Romero, SA; Sieck, DC; Struck, AJ; Turnbull, DW | 1 |
| Baynard, T; Behun, MA; Cook, MD; Fernhall, B; Halliwill, JR; Kappus, RM; Lane-Cordova, AD; Ranadive, SM; Wilund, KR; Woods, JA; Yan, H | 1 |
| Chimatadar, SA; Jattinagoudar, LN; Nandibewoor, ST | 1 |
| Elsässer, A; Gloekler, S; Praz, F; Schütz, T; Stortecky, S; Wenaweser, P; Windecker, S | 1 |
| Hashimoto, S; Hasunuma, T; Imai, H; Inoue, Y; Kotegawa, T; Luo, J; Ohashi, K; Ohyama, T; Uemura, N | 1 |
| Sawatsubashi, M | 1 |
| Asako, M; Gotoh, M; Honda, T; Nomura, Y; Ohashi, Y; Okubo, K; Saito, A; Togawa, M | 1 |
| Jeon, JY; Kim, DS; Kim, MG; Kim, Y | 1 |
| Cohen, PR; Greywal, T | 1 |
| Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E | 1 |
| Cieślińska, A; Fiedorowicz, E; Kordulewska, NK; Kostyra, E; Matysiewicz, M; Sienkiewicz-Szłapka, E | 1 |
| Dhaneshwar, SS; Singh, P | 1 |
| Bedada, SK; Boga, PK | 1 |
| Sjögren, E; Tannergren, C; Thörn, H | 1 |
| Akatsu, C; Fukui, H; Hishinuma, S; Kosaka, K; Shoji, M; Uesawa, Y | 1 |
| Howard, KD; Li, F; Myers, MJ | 1 |
| Appani, R; Bedada, SK; Boga, PK | 1 |
| Gerber, JP; Milne, RW; Turkanovic, J; Ward, MB | 1 |
| Kim, RB; Tirona, RG; Wilson, A | 1 |
| Annaert, P; Bouillon, T; de Loor, H; Kuypers, D; Vanhove, T | 1 |
| Feng, L; Li, B; Li, F; Liu, Y; Shi, Y; Wang, J; Yan, M | 1 |
| Bigliardi, PL; Santosa, A; Teo, SL | 1 |
| Hamada, Y; Kitaura, K; Kumagai, K; Matsubara, R; Nakasone, Y; Shigematsu, H; Suzuki, R; Suzuki, S | 1 |
| Kawakami, M; Kitada, R; Kurita, T; Tokumura, T | 1 |
| Bauerová, M; Fér, M; Golovko, O; Grabic, R; Klement, A; Koba, O; Kočárek, M; Kodešová, R; Nikodem, A | 1 |
| Abe, K; Ando, O; Imaoka, T; Karibe, T | 1 |
| Hasselstrøm, SB; Kristensen, DM; Munkboel, CH; Styrishave, B | 1 |
| Ando, K; Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Harada, H; Inamura, N; Izumi-Nakaseko, H; Lubna, NJ; Miyamoto, H; Naito, AT; Nakamura, Y; Sugiyama, A; Takagi, K | 1 |
| Czerwinska, K; Kublin, E; Malanowic, E; Mazurek, AP; Wyszomirska, E | 1 |
| Akamine, Y; Miura, M | 1 |
| Ji, Q; Liu, Y; Ye, XJ; Zhao, CL | 1 |
| Chikovani, T; Magen, E | 1 |
| Howard, K; Li, F; Martinez, M; Myers, MJ; Sharkey, M; Troutman, L; Yancy, HF | 1 |
| Choi, PM; Jiang, G; Li, J; Mueller, JF; O'Brien, JW; Thomas, KV | 1 |
| Bosma, R; Labeaga, L; Leurs, R; van den Bor, J; Vischer, HF | 1 |
| Akamine, Y; Uno, T; Yasui-Furukori, N | 1 |
| Cintra, MACT; Coelho, EB; Cusinato, DAC; Filgueira, GCO; Lanchote, VL; Rocha, A | 1 |
| Apfelbacher, CJ; Böhmer, MM; Carter, B; Jupiter, A; Matterne, U; Weisshaar, E | 1 |
| Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, N; Kostyra, E | 1 |
| Brzezinski, M; Ciecwierz, D; Fijalkowski, M; Jagielak, D; Jaguszewski, M; Klapkowski, A; Kowalik, M; Stanska, A | 1 |
| Baz, J; Brinkert, M; Cuevas, O; Jimenez, V; Molina, E; Moreno, R; Nietlispach, F; Pascual-Tejerina, V; Sánchez-Gila, J; Taramasso, M; Toggweiler, S | 1 |
| Matsune, S; Okubo, K; Otsuka, H; Otsuka, K | 1 |
| Enk, CD; Hodak, E; Lapidoth, M; Levi, A; Mazor, S; Snast, I; Uvaidov, V | 1 |
| Azad, FJ; Derakhshan, A; Gachkar, L; Ghanei, M; Hajimahdipour, H; Khodadoost, M; Khoshkhui, M; Taghipour, A; Yousefi, J | 1 |
| Chess-Williams, R; Moro, C; Stromberga, Z | 1 |
| Calvo, E; deCastro Carpeno, J; Kim, SW; Laus, G; Lee, JS; Mann, H; Moreno, V; Vishwanathan, K; Weilert, D | 1 |
| Bershow, A; Crowson, AN; Lee, KR | 1 |
| Chwała, B; Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E; Moszyńska, M | 1 |
| Dresser, GK; Griffin, KE; Kim, RB; Knauer, MJ; Li, MMJ; Lin, K; Mansell, SE; Medwid, S; Schmerk, CL; Schwarz, UI; Tirona, RG; Yousif, MD; Zhu, C | 1 |
| Krecisz, B; Kucharczyk, M; Slowik-Rylska, M | 1 |
| Bernstein, DI; Hassoun, Y; Stevenson, MR | 1 |
| Bi, Y; Chen, Y; Chen, ZS; Cui, Y; Fu, W; Hettinghouse, A; Lei, ZN; Liu, CJ; Liu, J; Liu, R; Wang, C; Wang, S; Xiao, G; Zhang, C; Zhao, X | 1 |
| Aoyama, T; Suzuki, K; Taniyama, K; Watanabe, Y | 1 |
| Chen, T; Fu, LX; Lu, YH; Wang, L; Zhou, PM | 1 |
| Guidon, AC; Long, AA; Slawski, BR; Suh, J | 1 |
| Lunardi, M; Pighi, M; Ribichini, FL | 1 |
| Bester, K; Castronovo, S; Falås, P; Henning, N; Jewell, KS; Ternes, TA; Wick, A | 1 |
| Alkhodair, A; Blanke, P; Fraser, R; Hensey, M; Kütting, M; Landes, U; Leipsic, J; Sathananthan, J; Sedaghat, A; Søndergaard, L; Toggweiler, S; Webb, JG; Wood, D | 1 |
| Antunes, P; Dall'Agnol, B; Ferreira, CAS; Padilha, T; Reck, J; Schott, D; Souza, GD; Souza, UA; Webster, A | 1 |
| Huang, CZ; Jiang, ZH; Luo, Y; Peng, H; Wang, J | 1 |
| Kumar, V; Nalini, CN | 1 |
| Aoyagi, H; Hirasawa, N; Kajiwara, D; Miyoshi, K; Tanaka, K; Tsunekuni, K | 1 |
| Bednarczyk, D; Sanghvi, MV | 1 |
| Cavalli, RC; Coelho, EB; Lanchote, VL; Marques, MP; Moreira, FL; Pinto, LSR; Vale, GTD | 1 |
| Åsberg, A; Christensen, H; Egeland, EJ; Robertsen, I; Witczak, BJ; Zaré, HK | 1 |
| da Costa César, I; de Araújo, LL; de Castro, WV; de Lima Nascimento, M; de Oliveira, FM; Derendorf, H; do Carmo Vieira, M; do Nascimento, SB; Duarte-Almeida, JM; Siqueira, JM | 1 |
| Andersen, JT; Andersson, NW; Torp-Pedersen, C | 1 |
| Akhter, F; Jahan, H; Nandi, AK | 1 |
| Jiang, L; Jin, MM; Liu, L; Liu, M; Liu, PH; Liu, XD; Liu, XN; Wang, ZJ; Xie, QS; Zhang, JX; Zhu, L | 1 |
| Cavalli, RC; Duarte, G; Lanchote, VL; Moisés, ECD; Moreira, FL; Nardotto, GHB; Pinto, L | 1 |
| Cai, W; Chien, HC; Giacomini, KM; Khuri, N; Ni, Z; Pieper, LM; Pottel, J; Shoichet, BK; Spanogiannopoulos, P; Tsakalozou, E; Turnbaugh, PJ; Vora, B; Zhang, W; Zou, L | 1 |
| Hassan, K | 1 |
| Fér, M; Grabic, R; Grabicová, K; Klement, A; Kočárek, M; Kodešová, R; Nikodem, A; Schmidtová, Z; Švecová, H | 1 |
| Ito, S; Iwamoto, K; Kamimura, H; Mizunaga, M; Nakayama, K; Negoro, T; Nishiwaki, M; Nomura, Y; Suemizu, H; Yamazaki, H; Yoneda, N | 1 |
| Doi, M; Furuichi, Y; Takano, T; Tsuji, S | 1 |
| El-Bedaiwy, HM; El-Masry, SM; Helmy, SA | 1 |
| Melby, PC; Osorio, EY; Peniche, AG; Travi, BL | 1 |
| Fukai, K; Kusutani, N; Maekawa, N; Nishida, M; Sowa-Osako, J | 1 |
| Cheng, R; Huang, X; Jiang, Z; Wu, W; Zhang, L | 1 |
| Bapat, P; Berger, H; de Carvalho Cavalli, R; de Lima Moreira, F; Koren, G; Lanchote, VL; Lubetsky, A; Pinto, L | 1 |
| Abalenikhina, YV; Chernykh, IV; Erokhina, PD; Shchulkin, AV; Yakusheva, EN | 1 |
| Baz, JA; Berenguer, A; Cantón, T; Galeote, G; Gonzálvez-García, A; Hernández, U; Jiménez-Valero, S; Jurado-Román, A; Lázaro, E; Moreno, R; Moreu, J; Moya, H | 1 |
| Abe, M; Ishii, M; Kikuchi, T; Morimoto, K; Ogihara, T; Oikawa, E; Sasaki, M; Tomita, M | 1 |
| Baz, JA; Iñiguez, A; Lehtola, H; Moccetti, F; Niemelä, M; Piuhola, J; Toggweiler, S; Tonino, PAL; van Nunen, LX; Wolfrum, M | 1 |
| Everardo, PG; Gabriela, SC; Magdalena, GS; Maria Elena, GP; Vanessa, CM | 1 |
| Fijałkowski, M; Gozdek, M; Jagielak, D; Jaguszewski, M; Kowalewski, M; Lango, R; Milan, J; Stańska, A; Targoński, R | 1 |
| Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H | 1 |
| Chen, Y; Hettinghouse, A; Liu, C; Liu, R; Zhao, X | 1 |
| Bauersachs, J; Kempf, T; Neuser, J; Widder, JD | 1 |
| De, D; Handa, S; Mahajan, R; Ningombam, A; Srivastava, N | 1 |
| Fromm, MF; Hoier, E; König, J; Misaka, S; Ogata, H; Ono, T; Ono, Y; Shimomura, K; Taudte, RV; Watanabe, H | 1 |
| Choi, SG; Kim, DW; Kim, SI; Kwon, HH; Ngo, VTH; Park, H; Park, JB; Pham, TL; Shin, HJ; Shin, J; Shin, N; Tran, Q; Wu, J | 1 |
| Ashmawy, SM; El Maghraby, GM; El Nashar, NF; Sultan, AA | 1 |
| Blaquera, CL; Capparelli, EV; Ma, JD; Nikanjam, M; Nolin, TD; Paine, MF; Penzak, SR; Piscitelli, J | 1 |
| Chen, Y; Liu, H; Luo, Z; Miao, Z; Ran, J; Tian, Y; Xie, Q; Yin, G; Zhang, Q | 1 |
| De Fer, BB; Lheritier-Barrand, M; Lucio, L; Rauch, C | 1 |
| Akiyoshi, T; Han, H; Imaoka, A; Morita, T; Nabeta, M; Ohtani, H; Tsuchitani, T; Yajima, K | 1 |
45 review(s) available for fexofenadine and terfenadine
| Article | Year |
|---|---|
Structural modifications that alter the P-glycoprotein efflux properties of compounds.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Central Nervous System Agents; Central Nervous System Diseases; Drug Design; Humans; Models, Molecular; Permeability; Structure-Activity Relationship | 2012 |
CNS drug design: balancing physicochemical properties for optimal brain exposure.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Central Nervous System Agents; Drug Design; Humans; Models, Molecular; Permeability | 2015 |
Is my antihistamine safe?
Topics: Adverse Drug Reaction Reporting Systems; Histamine Antagonists; Histamine H1 Antagonists; Humans; Patient Selection; Terfenadine; United States; United States Food and Drug Administration | 1997 |
Fexofenadine.
Topics: Animals; Histamine Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria | 1998 |
Pharmacokinetic overview of oral second-generation H1 antihistamines.
Topics: Astemizole; Blood-Brain Barrier; Cetirizine; Histamine H1 Antagonists; Humans; Loratadine; Structure-Activity Relationship; Terfenadine; Therapeutic Equivalency; Torsades de Pointes | 1998 |
Cardiovascular safety of fexofenadine HCl.
Topics: Double-Blind Method; Drug Interactions; Electrocardiography; Heart Conduction System; Histamine Antagonists; Humans; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Terfenadine | 1999 |
Variations among non-sedating antihistamines: are there real differences?
Topics: Astemizole; Benzimidazoles; Butyrophenones; Central Nervous System; Cetirizine; Drug Interactions; Heart; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Piperidines; Potassium Channel Blockers; Terfenadine; Triprolidine | 1999 |
The systemic safety of fexofenadine HCl.
Topics: Aged; Child; Drug Interactions; Drug Overdose; Histamine H1 Antagonists; Humans; Kidney Diseases; Liver Diseases; Psychomotor Performance; Terfenadine | 1999 |
Fexofenadine hydrochloride--a new anti-histaminic drug.
Topics: Chronic Disease; Clinical Trials as Topic; Drug Interactions; Histamine H1 Antagonists; Humans; Patient Selection; Rhinitis, Allergic, Seasonal; Safety; Terfenadine; Urticaria | 2001 |
[The effect of second generation histamine antagonists on the heart].
Topics: Animals; Area Under Curve; Astemizole; Butyrophenones; Electrocardiography; Heart; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Tachycardia; Terfenadine; Torsades de Pointes | 2001 |
Are antihistamines useful in managing asthma?
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Loratadine; Mannitol; Quinolines; Rhinitis; Sulfides; Terfenadine | 2002 |
Review of fexofenadine in the treatment of chronic idiopathic urticaria.
Topics: Anti-Allergic Agents; Asia; Chronic Disease; Humans; North America; Terfenadine; Urticaria | 2002 |
[H1 histamine antagonists].
Topics: Acetates; Anti-Allergic Agents; Cetirizine; Chemistry, Pharmaceutical; Histamine H1 Antagonists; Humans; Hypersensitivity; Piperazines; Rhinitis; Terfenadine; Urticaria | 2003 |
[Clinical aspects of anti-inflammatory action of antihistamines].
Topics: Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Piperazines; Terfenadine | 2003 |
Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment.
Topics: Anti-Allergic Agents; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2003 |
Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.
Topics: Anti-Allergic Agents; Cell Adhesion Molecules; Histamine H1 Antagonists; Humans; Hypersensitivity; Leukocytes; Mast Cells; Terfenadine; Treatment Outcome | 2003 |
Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.
Topics: Animals; Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Histamine H1 Antagonists; Loratadine; Piperidines; Terfenadine | 2004 |
Venom immunotherapy: adverse reactions and treatment failure.
Topics: Histamine H1 Antagonists; Humans; Hypersensitivity; Immunotherapy; Risk Factors; Terfenadine; Treatment Failure; Venoms | 2004 |
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.
Topics: Absorption; Animals; Area Under Curve; Benzimidazoles; Biological Availability; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Metabolic Clearance Rate; Piperazines; Terfenadine; Tissue Distribution | 2004 |
Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.
Topics: Adolescent; Adult; Cetirizine; Child; Child, Preschool; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Nurse Practitioners; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2005 |
Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis.
Topics: Animals; Delayed-Action Preparations; Drug Therapy, Combination; Ephedrine; Humans; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.
Topics: Central Nervous System; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Quality of Life; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
New antihistamines: a critical view.
Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cyproheptadine; Heart Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Mast Cells; Piperazines; Receptors, Histamine H1; Terfenadine | 2006 |
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Long QT Syndrome; Loratadine; Piperazines; Practice Guidelines as Topic; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2006 |
Some pharmacokinetic aspects of the lipophilic terfenadine and zwitterionic fexofenadine in humans.
Topics: Animals; Anti-Allergic Agents; Biological Availability; Biotransformation; Blood Proteins; Half-Life; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine | 2007 |
Fexofenadine in pediatrics: oral tablet and suspension formulations.
Topics: Administration, Oral; Animals; Chemistry, Pharmaceutical; Child; Child, Preschool; Deglutition; Humans; Infant; Rhinitis, Allergic, Seasonal; Suspensions; Tablets; Terfenadine | 2008 |
Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
Topics: Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria | 2008 |
A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Clinical Trials as Topic; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Young Adult | 2009 |
Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.
Topics: Animals; Anti-Allergic Agents; Clinical Trials as Topic; Humans; Hypersensitivity; Terfenadine | 2009 |
Clinical pharmacokinetics of fexofenadine enantiomers.
Topics: Antifungal Agents; Calcium Channel Blockers; Drug Interactions; Histamine H1 Antagonists; Humans; Itraconazole; Stereoisomerism; Terfenadine; Verapamil | 2010 |
Psoriasis vulgaris and digestive system disorders: is there a linkage?
Topics: Adult; Clemastine; Digestive System Diseases; Disease Progression; Humans; Male; Psoriasis; Terfenadine | 2009 |
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Drug Interactions; Genotype; Humans; Pharmacogenetics; Phenotype; Polymorphism, Single Nucleotide; Prescription Drugs; Propanolamines; Quinidine; Reproducibility of Results; Terfenadine | 2010 |
Fruit juice inhibition of uptake transport: a new type of food-drug interaction.
Topics: Administration, Oral; Anti-Allergic Agents; Beverages; Biological Availability; Citrus; Citrus paradisi; Food-Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Organic Anion Transporters; Terfenadine | 2010 |
Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.
Topics: Adult; Child, Preschool; Double-Blind Method; Histamine H1 Antagonists, Non-Sedating; Humans; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2011 |
Quantification of fexofenadine in biological matrices: a review of bioanalytical methods.
Topics: Animals; Chromatography, Liquid; Humans; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria | 2012 |
[Pharmacotherapy of urticaria--an analysis of the discrepancies between guidelines of expert bodies, registration documents and evidence for the effectiveness of drugs].
Topics: Administration, Oral; Administration, Topical; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Glucocorticoids; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Piperidines; Poland; Practice Guidelines as Topic; Terfenadine; Treatment Outcome; Urticaria | 2013 |
Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin--a mini-review.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Citrus; Cytochrome P-450 Enzyme System; Hesperidin; Humans; Learning; Memory; Signal Transduction; Terfenadine | 2014 |
[Determinants of the stereoselective pharmacokinetics of fexofenadine].
Topics: Animals; Biological Transport; Humans; Membrane Transport Proteins; Polymorphism, Genetic; Stereoisomerism; Terfenadine | 2015 |
[Clinical Management of Japanese Cedar Pollinosis].
Topics: Administration, Inhalation; Cedrus; Desensitization, Immunologic; Disorders of Excessive Somnolence; Drug Combinations; Environmental Exposure; Glucocorticoids; Histamine H1 Antagonists, Non-Sedating; Humans; Nasal Obstruction; Nonprescription Drugs; Patient Satisfaction; Pollen; Practice Guidelines as Topic; Pseudoephedrine; Rhinitis, Allergic, Seasonal; Seasons; Surveys and Questionnaires; Terfenadine | 2016 |
An update on the clinical pharmacokinetics of fexofenadine enantiomers.
Topics: Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Drug Interactions; Humans; Organic Anion Transporters; Stereoisomerism; Terfenadine | 2018 |
Drug-Drug Interactions of P-gp Substrates Unrelated to CYP Metabolism.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Dabigatran; Digoxin; Drug Interactions; Humans; Propanolamines; Terfenadine | 2019 |
Oral H1 antihistamines as 'add-on' therapy to topical treatment for eczema.
Topics: Administration, Oral; Administration, Topical; Adult; Cetirizine; Chemotherapy, Adjuvant; Child; Eczema; Histamine H1 Antagonists; Humans; Loratadine; Outcome Assessment, Health Care; Pruritus; Randomized Controlled Trials as Topic; Terfenadine | 2019 |
Antihistamine effects and safety of fexofenadine: a systematic review and Meta-analysis of randomized controlled trials.
Topics: Cognition; Drug-Related Side Effects and Adverse Reactions; Histamine H1 Antagonists, Non-Sedating; Humans; Psychomotor Performance; Randomized Controlled Trials as Topic; Terfenadine | 2019 |
A Review of Different Analytical Techniques for Fexofenadine Hydrochloride and Montelukast Sodium in Different Matrices.
Topics: Acetates; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chemistry Techniques, Analytical; Cyclopropanes; Drug Monitoring; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Quinolines; Sulfides; Terfenadine | 2021 |
206 trial(s) available for fexofenadine and terfenadine
| Article | Year |
|---|---|
The clinical pharmacology of fexofenadine in children.
Topics: Child; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Terfenadine | 1996 |
Effect of food on the bioavailability of fexofenadine hydrochloride (MDL 16455A).
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Diet; Dietary Fats; Fasting; Food-Drug Interactions; Histamine Antagonists; Humans; Intestinal Absorption; Male; Mass Spectrometry; Terfenadine | 1997 |
Efficacy and safety of fexofenadine hydrochloride for treatment of seasonal allergic rhinitis.
Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Female; Histamine Antagonists; Humans; Male; Middle Aged; Placebos; Rhinitis, Allergic, Seasonal; Single-Blind Method; Terfenadine | 1997 |
Peripheral H1-blockade effect of fexofenadine.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Histamine H1 Antagonists; Humans; Male; Terfenadine | 1997 |
Onset of action, efficacy, and safety of a single dose of fexofenadine hydrochloride for ragweed allergy using an environmental exposure unit.
Topics: Adolescent; Adult; Aged; Child; Double-Blind Method; Environmental Exposure; Female; Histamine Antagonists; Humans; Hypersensitivity; Male; Middle Aged; Pollen; Terfenadine | 1997 |
Fexofenadine's effects, alone and with alcohol, on actual driving and psychomotor performance.
Topics: Adult; Alcohol Drinking; Anti-Allergic Agents; Automobile Driving; Clemastine; Cross-Over Studies; Double-Blind Method; Female; Histamine Antagonists; Humans; Male; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Terfenadine | 1998 |
Atorvastatin does not produce a clinically significant effect on the pharmacokinetics of terfenadine.
Topics: Adolescent; Adult; Aged; Atorvastatin; Drug Interactions; Female; Heart Rate; Heptanoic Acids; Histamine H1 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Terfenadine | 1998 |
Dose proportionality and comparison of single and multiple dose pharmacokinetics of fexofenadine (MDL 16455) and its enantiomers in healthy male volunteers.
Topics: Adult; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Histamine H1 Antagonists; Humans; Male; Middle Aged; Spectrometry, Fluorescence; Stereoisomerism; Terfenadine | 1998 |
Pharmacokinetics, pharmacodynamics, and tolerance of single- and multiple-dose fexofenadine hydrochloride in healthy male volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Heart Conduction System; Histamine Antagonists; Humans; Male; Middle Aged; Reference Values; Regression Analysis; Terfenadine | 1998 |
Link between patient preferences and treatment outcomes in seasonal allergic rhinitis: an empiric investigation.
Topics: Adult; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Patient Satisfaction; Rhinitis, Allergic, Perennial; Surveys and Questionnaires; Terfenadine; Treatment Outcome | 1999 |
Comparison of the effects of terfenadine with fexofenadine on nasal provocation tests with allergen.
Topics: Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Nasal Provocation Tests; Otolaryngology; Peak Expiratory Flow Rate; Rhinitis, Allergic, Seasonal; Terfenadine | 1999 |
The efficacy and safety of fexofenadine HCl and pseudoephedrine, alone and in combination, in seasonal allergic rhinitis.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Child; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Efficiency; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Single-Blind Method; Terfenadine; Therapeutic Equivalency; Work | 1999 |
A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function.
Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time; Terfenadine; Wrist | 1999 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria | 1999 |
Cardiovascular safety of fexofenadine HCl.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Electrocardiography; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Torsades de Pointes | 1999 |
Once-daily fexofenadine HCl improves quality of life and reduces work and activity impairment in patients with seasonal allergic rhinitis.
Topics: Activities of Daily Living; Adolescent; Aged; Anti-Allergic Agents; Child; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Quality of Life; Rhinitis, Allergic, Seasonal; Surveys and Questionnaires; Terfenadine; Treatment Outcome; Work Capacity Evaluation | 1999 |
Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Terfenadine; Time Factors | 1999 |
A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pruritus; Terfenadine; Treatment Outcome; Urticaria | 1999 |
Antihistamines and aircrew: usefulness of fexofenadine.
Topics: Adult; Aerospace Medicine; Attention; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Promethazine; Sleep Stages; Terfenadine | 2000 |
Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator.
Topics: Adult; Automobile Driving; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Ethanol; Female; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Iowa; Male; Markov Chains; Middle Aged; Monte Carlo Method; Placebos; Rhinitis, Allergic, Seasonal; Sleep Stages; Terfenadine | 2000 |
Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Chronic Disease; Disorders of Excessive Somnolence; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Female; Headache; Histamine H1 Antagonists; Humans; Male; Middle Aged; Nausea; Terfenadine; Therapeutic Equivalency; Urticaria; Xerophthalmia; Xerostomia | 2000 |
Reduction of side-effects from ultrarush immunotherapy with honeybee venom by pretreatment with fexofenadine: a double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Angioedema; Anti-Allergic Agents; Bee Venoms; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypersensitivity, Immediate; Male; Middle Aged; Pruritus; Skin Tests; Terfenadine; Urticaria | 2000 |
Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis.
Topics: Adolescent; Adult; Child; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Quality of Life; Rhinitis, Allergic, Seasonal; Surveys and Questionnaires; Terfenadine; Treatment Outcome | 2000 |
Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Quality of Life; Terfenadine; Urticaria | 2000 |
Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: a double-blind comparison with crossover treatment of nonresponders.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Cross-Over Studies; Double-Blind Method; Female; Humans; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Terfenadine | 2000 |
The changing face of antihistamines and cardiac adverse drug reactions: a clinical perspective.
Topics: Cardiovascular Diseases; Drug Interactions; Electrocardiography; Erythromycin; Female; Histamine H1 Antagonists; Humans; Male; Rhinitis, Allergic, Seasonal; Terfenadine; Torsades de Pointes | 2000 |
Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.
Topics: Acetates; Adult; Aged; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Middle Aged; Quinolines; Sulfides; Terfenadine; Treatment Outcome; Urticaria | 2001 |
Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.
Topics: Acetates; Adult; Allergens; Cyclopropanes; Depression, Chemical; Dermatitis, Allergic Contact; Drug Therapy, Combination; Female; Histamine; Humans; Injections; Leukotriene D4; Male; Middle Aged; Quinolines; Sulfides; Terfenadine; Time Factors | 2001 |
Skin concentrations of H1-receptor antagonists.
Topics: Adult; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypersensitivity, Delayed; Male; Prospective Studies; Skin; Terfenadine | 2001 |
The effect of rifampin administration on the disposition of fexofenadine.
Topics: Administration, Oral; Adult; Aged; Aging; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Drug Interactions; Enzyme Inhibitors; Female; Half-Life; Histamine H1 Antagonists; Humans; Male; Metabolic Clearance Rate; Rifampin; Sex Characteristics; Terfenadine | 2001 |
A non-comparative trial of the efficacy and safety of fexofenadine for treatment of perennial allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Drug Administration Schedule; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Multicenter Studies as Topic; Rhinitis, Allergic, Perennial; Terfenadine; Thailand; Time Factors | 2000 |
Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Terfenadine | 2001 |
Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Terfenadine; Thailand; Urticaria | 2001 |
Twenty-four hours of activity of cetirizine and fexofenadine in the skin.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Double-Blind Method; Drug Evaluation; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis; Skin; Skin Tests; Terfenadine; Time Factors | 2001 |
Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyclopropanes; Double-Blind Method; Drug Interactions; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Male; Mannitol; Middle Aged; Quinolines; Recovery of Function; Sulfides; Terfenadine; Time Factors | 2001 |
Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.
Topics: Adult; Anti-Allergic Agents; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Humans; Kinetics; Male; Poaceae; Pollen; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine | 2001 |
Safety of fexofenadine in children treated for seasonal allergic rhinitis.
Topics: Asthma; Child; Double-Blind Method; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Therapeutic Equivalency | 2001 |
Fexofenadine reduces nasal congestion in perennial allergic rhinitis.
Topics: Adolescent; Adult; Animals; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Mites; Nasal Mucosa; Pilot Projects; Rhinitis, Allergic, Perennial; Sneezing; Terfenadine; Treatment Outcome | 2001 |
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
Topics: Administration, Oral; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Beverages; Biological Availability; Carrier Proteins; Citrus; Double-Blind Method; Female; Flavonoids; Food-Drug Interactions; Fruit; HeLa Cells; Histamine H1 Antagonists; Humans; Intestinal Absorption; Male; Malus; Membrane Transport Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Symporters; Terfenadine | 2002 |
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria | 2002 |
Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.
Topics: Administration, Oral; Adult; Area Under Curve; Beverages; Biological Availability; Citrus; Confidence Intervals; Cross-Over Studies; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Terfenadine | 2002 |
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; CD56 Antigen; Female; Fluorescent Dyes; Genes, MDR; Genotype; Histamine H1 Antagonists; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Male; Polymorphism, Genetic; Rhodamine 123; RNA, Messenger; Sex Factors; Terfenadine | 2002 |
A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.
Topics: Acetates; Adult; Anti-Allergic Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Loratadine; Nasal Cavity; Poaceae; Pollen; Pulmonary Ventilation; Quinolines; Rhinitis, Allergic, Seasonal; Single-Blind Method; Skin Tests; Sulfides; Terfenadine | 2002 |
An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers.
Topics: Adult; Central Nervous System; Cognition; Cross-Over Studies; Differential Threshold; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Male; Middle Aged; Placebos; Promethazine; Psychomotor Performance; Reaction Time; Reference Values; Terfenadine | 2002 |
[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].
Topics: Adult; Aged; Anti-Allergic Agents; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Terfenadine; Urticaria | 2002 |
Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Chemokine CCL3; Chemokine CCL4; Cross-Over Studies; Cytokines; Double-Blind Method; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine H1 Antagonists; Humans; Intercellular Adhesion Molecule-1; Interleukin-4; Macrophage Inflammatory Proteins; Middle Aged; Nasal Mucosa; Nasal Provocation Tests; Plant Proteins; Rhinitis, Allergic, Perennial; Terfenadine; Tumor Necrosis Factor-alpha | 2002 |
Effect of St John's wort on the pharmacokinetics of fexofenadine.
Topics: Adult; Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Hypericum; Male; Reference Values; Terfenadine | 2002 |
Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit.
Topics: Adolescent; Adult; Aged; Child; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Nasal Decongestants; Rhinitis, Allergic, Seasonal; Terfenadine | 2002 |
Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge.
Topics: Administration, Intranasal; Administration, Topical; Adult; Allergens; Androstadienes; Anti-Allergic Agents; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Dibenzoxepins; Double-Blind Method; Drug Therapy, Combination; Female; Fluticasone; Histamine H1 Antagonists; Humans; Male; Olopatadine Hydrochloride; Ophthalmic Solutions; Rhinitis, Allergic, Perennial; Terfenadine; Treatment Outcome | 2002 |
Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.
Topics: Adult; Air Pollutants; Allergens; Cross-Over Studies; Double-Blind Method; Environmental Exposure; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Lung; Male; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine | 2002 |
The use of handheld computers in clinical trials.
Topics: Adult; Anti-Allergic Agents; Data Collection; Databases, Factual; Double-Blind Method; Humans; Mathematical Computing; Medical Records; Microcomputers; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Software Validation; Terfenadine | 2002 |
Clinical pharmacology of H1-antihistamines in the skin.
Topics: Adult; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Male; Skin; Skin Tests; Terfenadine | 2002 |
Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.
Topics: Adult; Arousal; Brain; Brain Chemistry; Cetirizine; Cognition; Cross-Over Studies; Discrimination, Psychological; Double-Blind Method; Doxepin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Receptors, Histamine H1; Sleep Stages; Terfenadine; Tomography, Emission-Computed | 2002 |
Effects of fexofenadine on the early response to nasal allergen challenge.
Topics: Adolescent; Adult; Allergens; Biomarkers; Capillary Permeability; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine Release; Humans; Male; Mast Cells; Middle Aged; Molecular Structure; Nasal Cavity; Nasal Provocation Tests; Pruritus; Rhinitis, Allergic, Seasonal; Serine Endopeptidases; Serum Albumin; Sneezing; Structure-Activity Relationship; Terfenadine; Therapeutic Irrigation; Tryptases | 2002 |
Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells.
Topics: Adult; Biopsy, Needle; Follicle Stimulating Hormone; Histamine H1 Antagonists; Humans; Infertility, Male; Male; Mast Cells; Middle Aged; Semen; Serine Endopeptidases; Sperm Count; Sperm Motility; Terfenadine; Testis; Tryptases; Turkey | 2002 |
Effect of fexofenadine hydrochloride on cedar pollinosis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cedrus; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Patient Satisfaction; Pollen; Premedication; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2003 |
Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cyclosporine; Cytochrome P-450 CYP3A; Drug Administration Schedule; Enzyme Induction; Female; Gene Expression Regulation; Genes, MDR; Humans; Hypericum; Intestinal Mucosa; Liver; Male; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Plant Preparations; Reference Values; Terfenadine | 2003 |
Failure of cetirizine and fexofenadine to prevent motion sickness.
Topics: Adult; Analysis of Variance; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Motion Sickness; Nausea; Terfenadine; Treatment Failure | 2003 |
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Piperazines; Respiratory Hypersensitivity; Terfenadine | 2003 |
The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.
Topics: Administration, Oral; Adult; Aerospace Medicine; Attention; Cognition; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Placebos; Reaction Time; Sleep Stages; Terfenadine | 2003 |
Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis.
Topics: Anti-Allergic Agents; Child; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Rhinitis, Allergic, Seasonal; Terfenadine | 2003 |
The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers.
Topics: Adult; Asian People; Biotransformation; Blood-Brain Barrier; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Japan; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time; Terfenadine | 2003 |
Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing.
Topics: Cross-Over Studies; Double-Blind Method; Gastrointestinal Diseases; Histamine; Histamine H1 Antagonists; Humans; Plant Preparations; Skin; Skin Tests; Terfenadine; Time Factors | 2003 |
Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).
Topics: Adolescent; Adult; Attention; Cognition; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Reaction Time; Sleep Stages; Terfenadine | 2003 |
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine | 2002 |
Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis.
Topics: Adolescent; Adult; Ambrosia; Anti-Allergic Agents; Child; Conjunctivitis, Allergic; Drug Therapy, Combination; Eye Diseases; Female; Humans; Male; Middle Aged; Nedocromil; Ophthalmic Solutions; Patient Satisfaction; Pollen; Quality of Life; Salvage Therapy; Seasons; Terfenadine; Treatment Outcome | 2003 |
H1-antihistaminic activity of cetirizine and fexofenadine in allergic children.
Topics: Anti-Allergic Agents; Cetirizine; Child; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Prospective Studies; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome | 2003 |
Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Dermatitis, Atopic; Dermatologic Agents; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Hydrocortisone; Male; Middle Aged; Pruritus; Terfenadine; Treatment Outcome | 2003 |
Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.
Topics: Adolescent; Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Histamine H1 Antagonists; Histamine Release; Humans; Loratadine; Male; Middle Aged; Reference Values; Skin Tests; Terfenadine; Time Factors; Treatment Outcome | 2003 |
A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive
Topics: Adult; Analysis of Variance; Automobile Driving; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Ethanol; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Psychomotor Performance; Reaction Time; Terfenadine | 2003 |
Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Child; Double-Blind Method; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Nasal Mucosa; Omalizumab; Patient Satisfaction; Quality of Life; Rhinitis, Allergic, Perennial; Terfenadine; Treatment Outcome | 2003 |
The effects of fexofenadine on reaction time, decision-making, and driver behavior.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Automobile Driving; Cohort Studies; Decision Making; Female; Humans; Male; Middle Aged; Psychomotor Performance; Reaction Time; Terfenadine | 2003 |
Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.
Topics: Administration, Intranasal; Administration, Oral; Administration, Topical; Adult; Aged; Allergens; Anti-Allergic Agents; Conjunctiva; Conjunctivitis, Allergic; Dibenzoxepins; Double-Blind Method; Female; Humans; Male; Middle Aged; Mometasone Furoate; Nasal Mucosa; Olopatadine Hydrochloride; Ophthalmic Solutions; Pregnadienediols; Rhinitis, Allergic, Perennial; Tablets; Terfenadine; Time Factors | 2003 |
Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sleep Stages; Terfenadine; Treatment Outcome | 2003 |
Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.
Topics: Adult; Algorithms; Anti-Allergic Agents; Area Under Curve; Biological Availability; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Intestinal Absorption; Intestines; Jejunum; Male; Membrane Transport Modulators; Membrane Transport Proteins; Regional Blood Flow; Spectrophotometry, Ultraviolet; Terfenadine; Verapamil | 2003 |
A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity.
Topics: Administration, Oral; Adolescent; Adult; Butyrophenones; Double-Blind Method; Female; Histamine Antagonists; Humans; Male; Middle Aged; Piperidines; Skin; Terfenadine | 2003 |
Effect of the second-generation antihistamine, fexofenadine, on cough reflex sensitivity and pulmonary function.
Topics: Adolescent; Adult; Capsaicin; Cough; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Male; Terfenadine | 2003 |
Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine.
Topics: Administration, Oral; Adult; Animals; Antigens, Dermatophagoides; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatophagoides farinae; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Male; Skin Tests; Terfenadine; Treatment Outcome | 2003 |
Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.
Topics: Adult; Chlorpheniramine; Choice Behavior; Cognition; Cross-Over Studies; Dibenzoxepins; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Male; Olopatadine Hydrochloride; Psychomotor Performance; Reaction Time; Terfenadine; Time Factors | 2003 |
Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Terfenadine; Treatment Outcome; Urticaria | 2004 |
Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.
Topics: Acetates; Adolescent; Adult; Ambrosia; Anti-Allergic Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Surveys and Questionnaires; Terfenadine; Treatment Outcome; Vasoconstrictor Agents | 2004 |
The effects of butterbur on the histamine and allergen cutaneous response.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Humans; Male; Petasites; Phytotherapy; Quinolines; Skin Tests; Sulfides; Terfenadine | 2004 |
Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Respiratory Hypersensitivity; Sulfides; Terfenadine; Treatment Outcome | 2004 |
A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.
Topics: Adult; Anti-Allergic Agents; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Nasal Provocation Tests; Petasites; Phytotherapy; Plant Extracts; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome | 2004 |
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Provocation Tests; Piperazines; Rhinitis, Allergic, Perennial; Terfenadine; Treatment Outcome | 2004 |
Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.
Topics: Acetates; Adult; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Combinations; Female; Humans; Leukotriene Antagonists; Male; Nucleotidases; Quinolines; Receptors, Histamine H1; Rhinitis, Allergic, Perennial; Sulfides; Terfenadine; Treatment Outcome | 2004 |
Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge.
Topics: Adult; Allergens; Anti-Allergic Agents; Benzimidazoles; Conjunctivitis, Allergic; Cytokines; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Interleukin-1; Interleukin-6; Male; Nasal Provocation Tests; Parietaria; Pollen; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Terfenadine; Tumor Necrosis Factor-alpha | 2004 |
Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies.
Topics: Anti-Allergic Agents; Child; Double-Blind Method; Female; Headache; Histamine H1 Antagonists; Humans; Male; Meta-Analysis as Topic; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2004 |
Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.
Topics: Adolescent; Adult; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Terfenadine; Urticaria | 2004 |
Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.
Topics: Adult; Brain; Carbon Radioisotopes; Cetirizine; Cross-Over Studies; Double-Blind Method; Doxepin; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Positron-Emission Tomography; Practice Guidelines as Topic; Psychomotor Performance; Receptors, Histamine H1; Sleep Stages; Terfenadine | 2004 |
Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.
Topics: Chronic Disease; Dermatology; Dose-Response Relationship, Drug; Double-Blind Method; Histamine H1 Antagonists; Humans; Outcome Assessment, Health Care; Predictive Value of Tests; Pruritus; Quality of Life; Reproducibility of Results; Sensitivity and Specificity; Sickness Impact Profile; Statistics as Topic; Terfenadine; Treatment Outcome; Urticaria | 2004 |
Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Incidence; Male; Middle Aged; Phthalazines; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2004 |
Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.
Topics: Adult; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Dibenzoxepins; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Olopatadine Hydrochloride; Piperidines; Psychomotor Performance; Pyridines; Sleep Stages; Terfenadine | 2004 |
Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.
Topics: Adult; Alfentanil; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Combinations; Female; Humans; Male; Terfenadine | 2005 |
Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Skin Tests; Terfenadine; Urticaria | 2004 |
H1 receptor-mediated vasodilatation contributes to postexercise hypotension.
Topics: Adult; Exercise; Female; Histamine H1 Antagonists; Humans; Hypotension; Male; Receptors, Histamine H1; Terfenadine; Vasodilation | 2005 |
Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.
Topics: Adult; Area Under Curve; Biological Availability; Calcium Channel Blockers; Cimetidine; Drug Interactions; Half-Life; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Probenecid; Terfenadine; Uricosuric Agents; Verapamil | 2005 |
Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season.
Topics: Adult; Allergens; Cryptomeria; Double-Blind Method; Efficiency; Female; Histamine H1 Antagonists; Humans; Japan; Male; Pollen; Quality of Life; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2005 |
CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations.
Topics: Adult; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Black or African American; Cytochrome P-450 CYP3A; Female; Genotype; Herb-Drug Interactions; Hispanic or Latino; Humans; Hypericum; Male; Midazolam; Middle Aged; Phenotype; Plant Preparations; Terfenadine; White People | 2005 |
Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides.
Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Citrus paradisi; Cross-Over Studies; Drinking; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Organic Anion Transporters; Peptides; Terfenadine; Water | 2005 |
The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.
Topics: Adult; Cetirizine; Cryptomeria; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Loratadine; Male; Middle Aged; Pollen; Quality of Life; Rhinitis, Allergic, Seasonal; Sneezing; Surveys and Questionnaires; Terfenadine | 2005 |
Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration.
Topics: Adult; Cetirizine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Nose Diseases; Patient Satisfaction; Piperazines; Terfenadine | 2005 |
Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Cross-Over Studies; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male; Rhinitis, Allergic, Perennial; Tablets; Terfenadine; Therapeutic Equivalency | 2005 |
Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Terfenadine; Urticaria | 2005 |
Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism.
Topics: Adult; Antifungal Agents; Area Under Curve; Cross-Over Studies; Double-Blind Method; Drug Interactions; Genes, MDR; Haplotypes; Histamine H1 Antagonists; Humans; Itraconazole; Male; Polymorphism, Genetic; Terfenadine | 2005 |
Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use.
Topics: Adult; Arousal; Attention; Automobile Driving; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Mental Processes; Reaction Time; Sleep Stages; Telephone; Terfenadine | 2005 |
A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance.
Topics: Adult; Attention; Behavior; Cross-Over Studies; Double-Blind Method; Electroencephalography; Electrooculography; Evoked Potentials; Female; Histamine H1 Antagonists; Humans; Male; Psychomotor Performance; Reaction Time; Stimulation, Chemical; Terfenadine | 2006 |
Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.
Topics: Adult; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Japan; Loratadine; Male; Middle Aged; Placebos; Prospective Studies; Terfenadine; United Kingdom; Urticaria | 2005 |
Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Albuterol; Androstadienes; Anti-Allergic Agents; Asthma; Biomarkers; Bronchial Provocation Tests; Drug Therapy, Combination; Eosinophil Cationic Protein; Eosinophils; Female; Fluticasone; Humans; Hypersensitivity, Immediate; Inflammation; Male; Nitric Oxide; Respiratory Function Tests; Salmeterol Xinafoate; Terfenadine; Treatment Outcome | 2005 |
[Serum sICAM-1 in patients suffering from allergic rhinitis treated with fexofenadine or fluticasone].
Topics: Adolescent; Adult; Androstadienes; Anti-Allergic Agents; Female; Fluticasone; Humans; Intercellular Adhesion Molecule-1; Male; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2004 |
Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis.
Topics: Adolescent; Animals; Anti-Allergic Agents; Cats; Child; Cross-Over Studies; Double-Blind Method; Environmental Exposure; Female; Forced Expiratory Volume; Glycoproteins; Humans; Male; Placebos; Rhinitis, Allergic, Perennial; Terfenadine; Time Factors; Treatment Outcome | 2006 |
Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Capsules; Colon; Drug Synergism; Erythromycin; Female; Humans; Ileum; Intestinal Absorption; Intestinal Mucosa; Intubation; Jejunum; Male; Polyethylene; Reference Values; Terfenadine; Time Factors | 2006 |
The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Female; Half-Life; Histamine H1 Antagonists; Humans; Male; Stereoisomerism; Terfenadine; Tissue Distribution; Verapamil | 2006 |
The efficacy and safety of 30 mg fexofenadine HCl bid in pediatric patients with allergic rhinitis.
Topics: Anti-Allergic Agents; Asian People; Child; Female; Histamine H1 Antagonists; Humans; Male; Multicenter Studies as Topic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2005 |
Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.
Topics: Adult; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Diltiazem; Drug Administration Schedule; Drug Interactions; Female; Histamine H1 Antagonists; Humans; Itraconazole; Male; Terfenadine; Time Factors | 2006 |
Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis.
Topics: Adult; Anti-Allergic Agents; Cedrus; Dermatophagoides farinae; Desensitization, Immunologic; Female; Histamine H1 Antagonists; Humans; Male; Multicenter Studies as Topic; Pollen; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.
Topics: Adult; Cognition; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Terfenadine; Tomography, Emission-Computed, Single-Photon; Tropanes | 2006 |
Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.
Topics: Adult; Antifungal Agents; Cross-Over Studies; Drug Interactions; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Itraconazole; Japan; Male; Terfenadine | 2006 |
Time-dependent interaction between lopinavir/ritonavir and fexofenadine.
Topics: Administration, Oral; Adult; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Drug Combinations; Drug Interactions; Female; Genotype; Histamine H1 Antagonists; HIV Protease Inhibitors; Humans; Liver; Lopinavir; Male; Middle Aged; Organic Anion Transporters; Pyrimidinones; Ritonavir; Terfenadine; Time Factors | 2006 |
Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.
Topics: Adult; Anti-Allergic Agents; Asian People; Chlorpheniramine; Cognition; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Japan; Male; Middle Aged; Psychomotor Performance; Sleep; Sleep, REM; Terfenadine | 2006 |
Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Double-Blind Method; Face; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Nasal Provocation Tests; Nose; Piperazines; Skin Temperature; Terfenadine; Thermography | 2006 |
Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Itraconazole; Male; Middle Aged; Terfenadine | 2006 |
Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography.
Topics: Acetonitriles; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Histamine H1 Antagonists, Non-Sedating; Humans; Linear Models; Molecular Structure; Phosphates; Potassium Compounds; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Stereoisomerism; Terfenadine | 2007 |
Treatment of allergic rhinitis can improve blood pressure control.
Topics: Adult; Analysis of Variance; Androstadienes; Anti-Allergic Agents; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Female; Fluticasone; Humans; Hypertension; Male; Middle Aged; Quality of Life; Rhinitis, Allergic, Perennial; Severity of Illness Index; Sodium Chloride; Surveys and Questionnaires; Terfenadine; Treatment Outcome | 2006 |
Onset of action of fexofenadine hydrochloride 60 mg/pseudoephedrine hydrochloride 120 mg in subjects aged 12 years with moderate to severe seasonal allergic rhinitis: a pooled analysis of two single-dose, randomized, double-blind, placebo-controlled aller
Topics: Adult; Allergens; Anti-Allergic Agents; Demography; Double-Blind Method; Ephedrine; Female; Humans; Male; Placebos; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2006 |
Intestinal drug transporter expression and the impact of grapefruit juice in humans.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beverages; Biological Availability; Blotting, Western; Carrier Proteins; Citrus paradisi; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fluorescent Antibody Technique; Food-Drug Interactions; Histamine H1 Antagonists; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Middle Aged; Organic Anion Transporters; Pharmaceutical Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA; Terfenadine | 2007 |
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.
Topics: Adult; Anticoagulants; Beverages; Citrus paradisi; Cross-Over Studies; Data Interpretation, Statistical; Double-Blind Method; Drug Interactions; Female; Flavanones; Furocoumarins; HeLa Cells; Hesperidin; Histamine H1 Antagonists; Humans; Male; Middle Aged; Organic Anion Transporters; Reproducibility of Results; Terfenadine | 2007 |
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.
Topics: Adolescent; Chronic Disease; Double-Blind Method; Efficiency; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Quality of Life; Surveys and Questionnaires; Terfenadine; Urticaria | 2007 |
Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration.
Topics: Administration, Oral; Adolescent; Adult; Anti-Allergic Agents; Cross-Over Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Tablets; Terfenadine; Therapeutic Equivalency | 2007 |
Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old.
Topics: Age Factors; Anti-Allergic Agents; Body Temperature; Child, Preschool; Cough; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Infant; Male; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Vomiting | 2007 |
Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Ginkgo biloba; HIV Protease Inhibitors; Humans; Lopinavir; Male; Midazolam; Phytotherapy; Plant Extracts; Protease Inhibitors; Pyrimidinones; Ritonavir; Terfenadine | 2008 |
Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.
Topics: Administration, Oral; Blood Pressure; Body Temperature; Body Weight; Child, Preschool; Electrocardiography; Histamine H1 Antagonists, Non-Sedating; Humans; Infant; Male; Rhinitis, Allergic, Perennial; Statistics, Nonparametric; Terfenadine | 2007 |
The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Drug Combinations; Drug Interactions; Female; Humans; Itraconazole; Male; Terfenadine | 2008 |
Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.
Topics: Adult; Cetirizine; Cross-Over Studies; Dibenzoxepins; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Histamine Antagonists; Humans; Iontophoresis; Male; Olopatadine Hydrochloride; Skin; Terfenadine; Urticaria | 2008 |
Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cystic Fibrosis; DNA; Female; Flow Cytometry; Genotype; Histamine H1 Antagonists; Humans; Iothalamic Acid; Kidney; Male; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Probenecid; Prospective Studies; Renal Agents; T-Lymphocytes; Terfenadine | 2008 |
Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.
Topics: Administration, Oral; Adolescent; Adult; Child; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity, Immediate; Injections, Intramuscular; Male; Middle Aged; Skin Tests; Terfenadine; Time Factors; Treatment Outcome | 2008 |
The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chlorpheniramine; Cross-Over Studies; Double-Blind Method; Genotype; Half-Life; Histamine H1 Antagonists; Humans; Korea; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Genetic; Sleep; Sleep, REM; Terfenadine | 2008 |
Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients.
Topics: Adult; Air; Anti-Allergic Agents; Anti-Inflammatory Agents; Cryptomeria; Female; Humans; Male; Pollen; Prospective Studies; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Terfenadine | 2009 |
Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude.
Topics: Adult; Aerospace Medicine; Altitude; Anti-Allergic Agents; Attention; Cetirizine; Cognition; Double-Blind Method; Female; Humans; Male; Placebos; Reaction Time; Sleep Stages; Terfenadine | 2008 |
Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study.
Topics: Adult; Drug Resistance; Female; Histamine H1 Antagonists; Humans; Male; Pilot Projects; Prospective Studies; Pruritus; Terfenadine; Ultraviolet Therapy; Urticaria | 2008 |
Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.
Topics: Adolescent; Adult; Exercise; Female; Histamine H1 Antagonists, Non-Sedating; Hot Temperature; Humans; Hypotension; Male; Syncope; Terfenadine; Young Adult | 2008 |
Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Cross-Over Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Quercetin; Reference Values; Spectrometry, Fluorescence; Terfenadine | 2009 |
Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.
Topics: Adult; Alfentanil; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Intestines; Liver; Male; Methadone; Narcotics; Pupil; Ritonavir; Stereoisomerism; Terfenadine | 2008 |
Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.
Topics: Acetylcholine; Activities of Daily Living; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Antigens, Plant; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Chamaecyparis; Chromones; Cough; Cryptomeria; Eosinophils; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Male; Middle Aged; Nasal Mucosa; Phenothiazines; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Young Adult | 2009 |
Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Drug Interactions; Female; Humans; Male; Terfenadine; Verapamil; Young Adult | 2009 |
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2009 |
Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit.
Topics: Adult; Allergens; Cryptomeria; Dibenzoxepins; Double-Blind Method; Female; Follow-Up Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Motor Activity; Olopatadine Hydrochloride; Pollen; Rhinitis, Allergic, Seasonal; Sleep; Sneezing; Terfenadine; Treatment Outcome | 2009 |
Bioequivalence of fexofenadine tablet formulations assessed in healthy Iranian volunteers.
Topics: Adult; Analysis of Variance; Anti-Allergic Agents; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Iran; Male; Single-Blind Method; Tablets; Terfenadine; Therapeutic Equivalency; Young Adult | 2009 |
Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Methylphenidate; Modafinil; Psychomotor Performance; Reaction Time; Terfenadine; Young Adult | 2009 |
Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Male; Quinolines; Rhinitis, Allergic, Perennial; Rhinometry, Acoustic; Sulfides; Terfenadine | 2009 |
Effects of the P-glycoprotein inducer carbamazepine on fexofenadine pharmacokinetics.
Topics: Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Drug Interactions; Female; Histamine H1 Antagonists; Humans; Male; Terfenadine; Young Adult | 2009 |
The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber.
Topics: Adolescent; Adult; Allergens; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Cross-Over Studies; Double-Blind Method; Eye Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Middle Aged; Nasal Mucosa; Nose Diseases; Ophthalmic Solutions; Piperidines; Placebos; Rhinitis, Allergic, Seasonal; Terfenadine | 2010 |
Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.
Topics: Administration, Oral; Anti-Allergic Agents; Biological Transport; Calibration; Chromatography, Liquid; Drug Stability; Humans; Limit of Detection; Quality Control; Reference Standards; Tandem Mass Spectrometry; Terfenadine | 2010 |
Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis.
Topics: Administration, Oral; Antigens, Plant; Double-Blind Method; Histamine H1 Antagonists, Non-Sedating; Humans; Nasal Obstruction; Nasal Provocation Tests; Pollen; Pulmonary Ventilation; Recovery of Function; Rhinitis, Allergic, Seasonal; Rhinomanometry; Terfenadine | 2009 |
Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Interactions; Humans; Male; Metronidazole; Terfenadine | 2010 |
Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability.
Topics: Administration, Oral; Adolescent; Adult; Anti-Allergic Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Humans; Male; Middle Aged; Terfenadine; Young Adult | 2010 |
Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Chromatography, Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Terfenadine; Young Adult | 2010 |
Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.
Topics: Acetates; Adult; Airway Resistance; Anti-Allergic Agents; Case-Control Studies; Cyclopropanes; Drug Therapy, Combination; Female; Humans; Leukotriene Antagonists; Male; Pain Measurement; Patient Satisfaction; Quinolines; Rhinitis, Allergic, Perennial; Rhinomanometry; Sulfides; Terfenadine; Treatment Outcome | 2010 |
The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans.
Topics: Adult; Animals; Anti-Allergic Agents; Area Under Curve; Beverages; Biological Transport; GABA Modulators; Humans; Male; Malus; Midazolam; Organic Anion Transporters; Polymorphism, Single Nucleotide; Terfenadine; Xenopus laevis; Young Adult | 2011 |
Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose.
Topics: Administration, Oral; Adrenergic beta-1 Receptor Antagonists; Adult; Area Under Curve; Atenolol; Beverages; Celiprolol; Citrus paradisi; Cross-Over Studies; Dose-Response Relationship, Drug; Food-Drug Interactions; Humans; Male; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Genetic; Terfenadine; Young Adult | 2012 |
Influence of Panax ginseng on cytochrome P450 (CYP)3A and P-glycoprotein (P-gp) activity in healthy participants.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Monitoring; Drugs, Chinese Herbal; Female; Half-Life; Herb-Drug Interactions; Humans; Intestinal Absorption; Male; Metabolic Clearance Rate; Midazolam; Panax; Plant Roots; Terfenadine; Young Adult | 2012 |
Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers.
Topics: Adult; Anti-Allergic Agents; Anticonvulsants; Area Under Curve; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Drug Interactions; Humans; Male; Stereoisomerism; Terfenadine; Young Adult | 2012 |
Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
Topics: Adult; Amides; Antihypertensive Agents; Beverages; Biological Transport; Citrus paradisi; Cross-Over Studies; Flavanones; Food-Drug Interactions; Fruit; Fumarates; Half-Life; HEK293 Cells; Humans; Intestinal Mucosa; Male; Organic Anion Transporters; Recombinant Proteins; Renin; Terfenadine; Young Adult | 2012 |
Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers.
Topics: Adolescent; Dibenzoxepins; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Olopatadine Hydrochloride; Promethazine; Pruritus; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria; Young Adult | 2012 |
A randomized control trail of stepwise treatment with fluticasone propionate nasal spray and fexofenadine hydrochloride tablet for seasonal allergic rhinitis.
Topics: Adult; Androstadienes; Anti-Allergic Agents; Female; Fluticasone; Humans; Male; Middle Aged; Nasal Sprays; Pollen; Rhinitis, Allergic, Seasonal; Tablets; Terfenadine; Treatment Outcome | 2012 |
The effects of an H3 receptor antagonist (PF-03654746) with fexofenadine on reducing allergic rhinitis symptoms.
Topics: Adult; Ambrosia; Anti-Allergic Agents; Cross-Over Studies; Cyclobutanes; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists, Non-Sedating; Histamine H3 Antagonists; Humans; Male; Middle Aged; Nasal Provocation Tests; Pyrrolidines; Rhinitis, Allergic, Seasonal; Skin Tests; Terfenadine; Young Adult | 2012 |
Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers.
Topics: Adolescent; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Drug Interactions; Female; Fluvoxamine; Half-Life; Humans; Intestine, Small; Liver; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Terfenadine; Young Adult | 2012 |
Sustained postexercise vasodilatation and histamine receptor activation following small muscle-mass exercise in humans.
Topics: Blood Pressure; Exercise; Female; Heart Rate; Humans; Leg; Male; Muscle, Skeletal; Ranitidine; Receptors, Histamine; Terfenadine; Vasodilation; Young Adult | 2013 |
Effect of coadministration of single and multiple doses of rifampicin on the pharmacokinetics of fexofenadine enantiomers in healthy subjects.
Topics: Adult; Aged; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Reference Values; Rifampin; Terfenadine; Young Adult | 2013 |
The inhibition by levocetirizine and fexofenadine of the histamine-induced wheal and flare response in healthy Caucasian and Japanese volunteers.
Topics: Adult; Asian People; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Germany; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Male; Pruritus; Skin; Terfenadine; Time Factors; Treatment Outcome; Urticaria; White People; Young Adult | 2013 |
Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; HIV Protease Inhibitors; Humans; Intestines; Liver; Liver-Specific Organic Anion Transporter 1; Male; Midazolam; Organic Anion Transporters; Pravastatin; Ritonavir; Saquinavir; Tandem Mass Spectrometry; Terfenadine; Young Adult | 2013 |
Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe.
Topics: Adult; Astragalus Plant; Astragalus propinquus; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Male; Polymorphism, Single Nucleotide; Substrate Specificity; Terfenadine; Therapeutic Equivalency | 2013 |
Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations.
Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Iontophoresis; Male; Pilot Projects; Pruritus; Terfenadine; Urticaria | 2013 |
The effects of antihistamines with varying anticholinergic properties on voluntary and involuntary movement.
Topics: Adult; Cholinergic Antagonists; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Promethazine; Reaction Time; Sleep Stages; Terfenadine; Tremor; Young Adult | 2013 |
A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect".
Topics: Adult; Animals; Anti-Allergic Agents; Beverages; Chlorocebus aethiops; Citrus paradisi; COS Cells; Coumarins; Cross-Over Studies; Estrone; Female; Flavonoids; Food-Drug Interactions; Fruit; HEK293 Cells; Humans; Male; Middle Aged; Organic Anion Transporters; Terfenadine; Young Adult | 2013 |
The effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial.
Topics: Acetates; Allergens; Animals; Asthma; Chi-Square Distribution; Child; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Pyroglyphidae; Quinolines; Reference Values; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sensitivity and Specificity; Skin Tests; Statistics, Nonparametric; Sulfides; Terfenadine; Urticaria | 2013 |
In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Breath Tests; Case-Control Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Flurbiprofen; Glomerulonephritis; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Terfenadine; Young Adult | 2014 |
Sensitive LC-MS/MS-ESI method for simultaneous determination of montelukast and fexofenadine in human plasma: application to a bioequivalence study.
Topics: Acetates; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclopropanes; Drug Stability; Humans; Linear Models; Male; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Single-Blind Method; Spectrometry, Mass, Electrospray Ionization; Sulfides; Tandem Mass Spectrometry; Terfenadine; Therapeutic Equivalency | 2014 |
Population pharmacokinetic analysis of fexofenadine in Japanese pediatric patients.
Topics: Adolescent; Asian People; Child; Child, Preschool; Female; Histamine H1 Antagonists; Humans; Infant; Japan; Male; Models, Biological; Terfenadine | 2014 |
Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers.
Topics: Adult; Animals; Anti-Allergic Agents; Area Under Curve; Beverages; Cross-Over Studies; Eating; Female; Food-Drug Interactions; Fruit; Histamine H1 Antagonists, Non-Sedating; Humans; Intestinal Absorption; Male; Malus; Oocytes; Organic Anion Transporters; RNA, Complementary; Stereoisomerism; Terfenadine; Xenopus laevis; Young Adult | 2014 |
Pharmacokinetics of fexofenadine in healthy Taiwanese volunteers.
Topics: Adult; Chromatography, Liquid; Humans; Male; Tandem Mass Spectrometry; Terfenadine | 2014 |
Effects of multiple-dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers.
Topics: Anti-Allergic Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP2B6 Inducers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Japan; Rifampin; Terfenadine | 2015 |
Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients.
Topics: Adult; Asian People; Benzimidazoles; China; Female; Genotyping Techniques; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoglobulin E; Loratadine; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, IgE; Terfenadine; Urticaria; Young Adult | 2015 |
Brain histamine H1 receptor occupancy measured by PET after oral administration of levocetirizine, a non-sedating antihistamine.
Topics: Administration, Oral; Brain; Carbon Radioisotopes; Cetirizine; Cross-Over Studies; Double-Blind Method; Doxepin; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Neuroimaging; Positron-Emission Tomography; Radioligand Assay; Receptors, Histamine H1; Sleep; Terfenadine; Young Adult | 2015 |
Comparison of the efficacy of olopatadine and fexofenadine in chronic idiopathic urticaria patients: a crossover study.
Topics: Adult; Anti-Allergic Agents; Chronic Disease; Cross-Over Studies; Dibenzoxepins; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Olopatadine Hydrochloride; Terfenadine; Treatment Outcome; Urticaria | 2015 |
Effects of Cremophor EL on the absorption of orally administered saquinavir and fexofenadine in healthy subjects.
Topics: Absorption, Physiological; Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP3A; Excipients; Glycerol; Healthy Volunteers; Humans; Male; Saquinavir; Substrate Specificity; Terfenadine | 2015 |
The change of pharmacokinetics of fexofenadine enantiomers through the single and simultaneous grapefruit juice ingestion.
Topics: Adult; Anti-Allergic Agents; Area Under Curve; Beverages; Citrus paradisi; Cross-Over Studies; Female; Food-Drug Interactions; Humans; Male; Organic Anion Transporters; Stereoisomerism; Terfenadine; Young Adult | 2015 |
Prediction of area under the curve for a p-glycoprotein, a CYP3A4 and a CYP2C9 substrate using a single time point strategy: assessment using fexofenadine, itraconazole and losartan and metabolites.
Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Itraconazole; Losartan; Polypharmacy; Terfenadine | 2016 |
A simulated car-driving study on the effects of acute administration of levocetirizine, fexofenadine, and diphenhydramine in healthy Japanese volunteers.
Topics: Adult; Asian People; Automobile Driving; Cetirizine; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Psychomotor Performance; Reaction Time; Terfenadine; Young Adult | 2016 |
Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method.
Topics: Adolescent; Adult; Bupropion; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dose-Response Relationship, Drug; Dried Blood Spot Testing; Drug Interactions; Female; Flurbiprofen; Genotyping Techniques; Humans; Male; Midazolam; Omeprazole; Phenotype; Terfenadine; Young Adult | 2016 |
No major effects of vitamin D3 (1,25 dihydroxyvitamin D3) on absorption and pharmacokinetics of folic acid and fexofenadine in healthy volunteers.
Topics: Administration, Oral; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Duodenum; Female; Folic Acid; Healthy Volunteers; Humans; Intestinal Absorption; Male; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Proton-Coupled Folate Transporter; RNA, Messenger; Terfenadine; Vitamin D; Young Adult | 2016 |
Evidence of a broad histamine footprint on the human exercise transcriptome.
Topics: Adult; Exercise; Female; Hemodynamics; Histamine; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Knee; Male; Muscle, Skeletal; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Terfenadine; Transcriptome; Young Adult | 2016 |
Differential Post-Exercise Blood Pressure Responses between Blacks and Caucasians.
Topics: Adolescent; Adult; Black People; Blood Pressure; Double-Blind Method; Exercise; Female; Heart Rate; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Leg; Male; Oxygen Consumption; Ranitidine; Regional Blood Flow; Terfenadine; Vascular Resistance; White People; Young Adult | 2016 |
The Pharmacokinetic Exposure to Fexofenadine is Volume-Dependently Reduced in Healthy Subjects Following Oral Administration With Apple Juice.
Topics: Administration, Oral; Beverages; Female; Healthy Volunteers; Humans; Male; Malus; Terfenadine | 2016 |
Efficacy and safety of bilastine in Japanese patients with perennial allergic rhinitis: A multicenter, randomized, double-blind, placebo-controlled, parallel-group phase III study.
Topics: Adult; Asian People; Benzimidazoles; Double-Blind Method; Female; Humans; Japan; Male; Middle Aged; Piperidines; Rhinitis, Allergic, Seasonal; Terfenadine | 2017 |
Fexofenadine, a Putative In Vivo P-glycoprotein Probe, Fails to Predict Clearance of the Substrate Tacrolimus in Renal Recipients.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Female; Humans; Kidney Transplantation; Liver-Specific Organic Anion Transporter 1; Male; Midazolam; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Polymorphism, Single Nucleotide; Solute Carrier Organic Anion Transporter Family Member 1B3; Tacrolimus; Terfenadine; Young Adult | 2017 |
[The effect of combined therapy on seasonal allergic rhinitis].
Topics: Administration, Intranasal; Budesonide; Double-Blind Method; Glucocorticoids; Humans; Leukotriene Antagonists; Loratadine; Quality of Life; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Terfenadine | 2016 |
Impact of ABCB1 genotype in Collies on the pharmacokinetics of R- and S-fexofenadine.
Topics: Animals; Anti-Allergic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dogs; Female; Genotype; Half-Life; Male; Terfenadine | 2018 |
Effects of a Novel Barley-Based Formulation on Allergic Rhinitis: A Randomized Controlled Trial.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Biomarkers; Child; Female; Histamine H1 Antagonists, Non-Sedating; Hordeum; Humans; Immunoglobulin E; Iran; Male; Middle Aged; Plant Extracts; Rhinitis, Allergic; Seeds; Terfenadine; Time Factors; Treatment Outcome; Young Adult | 2019 |
Modulation of Fexofenadine Pharmacokinetics by Osimertinib in Patients With Advanced EGFR-Mutated Non-Small Cell Lung Cancer.
Topics: Acrylamides; Aged; Aniline Compounds; Anti-Allergic Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; Drug Interactions; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Protein Kinase Inhibitors; Terfenadine | 2019 |
Bioavailability assessment of fexofenadine and montelukast in a fixed-dose combination tablet
Topics: Acetates; Area Under Curve; Biological Availability; Cross-Over Studies; Cyclopropanes; Humans; Quinolines; Rhinitis, Allergic; Sulfides; Tablets; Terfenadine | 2021 |
Addition of oral fexofenadine to topical therapy leads to a significantly greater reduction in the serum interleukin-31 levels in mild to moderate paediatric atopic dermatitis.
Topics: Administration, Topical; Child; Dermatitis, Atopic; Double-Blind Method; Humans; Interleukins; Prospective Studies; Tacrolimus; Terfenadine; Treatment Outcome | 2022 |
Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers.
Topics: Antioxidants; Catechin; Cross-Over Studies; Healthy Volunteers; HEK293 Cells; Humans; Pharmaceutical Preparations; Plant Extracts; Pseudoephedrine; Tea; Terfenadine | 2022 |
Bioequivalence of 2 Pediatric Formulations of Fexofenadine Hydrochloride Oral Suspension.
Topics: Adult; Child; Cross-Over Studies; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine; Therapeutic Equivalency | 2023 |
365 other study(ies) available for fexofenadine and terfenadine
| Article | Year |
|---|---|
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water | 1998 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.
Topics: Amino Acids, Aromatic; Cation Transport Proteins; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Indoles; Inhibitory Concentration 50; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Structural Homology, Protein; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2003 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Inhibitory effect of carboxylic acid group on hERG binding.
Topics: Benzamidines; Carboxylic Acids; Ether-A-Go-Go Potassium Channels; Factor Xa Inhibitors; Humans | 2006 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approach.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cisapride; Dimerization; Ether-A-Go-Go Potassium Channels; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Piperidines; Pyridines; Sequence Homology, Amino Acid; Terfenadine | 2009 |
Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.
Topics: Animals; Electrocardiography; Guinea Pigs; Histamine H1 Antagonists, Non-Sedating; Humans; Protein Binding; Receptors, Histamine H1; Structure-Activity Relationship; Terfenadine; Trans-Activators; Transcriptional Regulator ERG | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration.
Topics: Cholesterol Ester Transfer Proteins; Drug Discovery; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; ROC Curve | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition.
Topics: Animals; Body Weight; Brain; Carbazoles; Cyclohexanecarboxylic Acids; Diet, High-Fat; Dogs; Drug Evaluation, Preclinical; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Receptors, Pituitary Hormone; Structure-Activity Relationship | 2012 |
Repurposing the antihistamine terfenadine for antimicrobial activity against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Chemistry Techniques, Synthetic; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists, Non-Sedating; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Models, Molecular; Staphylococcus aureus; Structure-Activity Relationship; Terfenadine; Topoisomerase II Inhibitors | 2014 |
Determination of terfenadine and terfenadine acid metabolite in plasma using solid-phase extraction and high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Spectrometry, Fluorescence; Terfenadine | 1991 |
Investigation of the stereoselective metabolism of the chiral H1-antihistaminic drug terfenadine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Stereoisomerism; Terfenadine | 1995 |
Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography.
Topics: Administration, Oral; Adult; Animals; Brain; Carbon Radioisotopes; Chlorpheniramine; Doxepin; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Receptors, Histamine H1; Terfenadine; Tomography, Emission-Computed | 1995 |
From the Food and Drug Administration.
Topics: Animal Feed; Animals; Biological Products; Histamine Antagonists; Histamine H1 Antagonists; Humans; Prion Diseases; Ruminants; Terfenadine; United States; United States Department of Agriculture; United States Food and Drug Administration | 1997 |
[Introduction of a new antihistamine generation].
Topics: Histamine Antagonists; Histamine H1 Antagonists; Humans; Hypersensitivity; Hypersensitivity, Immediate; Terfenadine | 1997 |
[Drug side effects and their prevention].
Topics: Arrhythmias, Cardiac; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrocardiography; Histamine H1 Antagonists; Humans; Hypersensitivity; Mixed Function Oxygenases; Terfenadine | 1997 |
[Further development of terfenadine].
Topics: Clinical Trials as Topic; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Terfenadine; Urticaria | 1997 |
[Fexofenadine--progress in antihistamine therapy].
Topics: Histamine H1 Antagonists; Humans; Hypersensitivity; Hypersensitivity, Immediate; Terfenadine | 1997 |
Effect of fexofenadine on eosinophil-induced changes in epithelial permeability and cytokine release from nasal epithelial cells of patients with seasonal allergic rhinitis.
Topics: Cell Adhesion; Cell Membrane Permeability; Cells, Cultured; Chemokine CCL5; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytokines; Endothelium, Vascular; Eosinophils; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine Antagonists; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Microspheres; Nasal Mucosa; Opsonin Proteins; Proteins; Rhinitis, Allergic, Seasonal; T-Lymphocytes; Terfenadine | 1998 |
Terfenadine and fexofenadine reduce in vitro ICAM-1 expression on human continuous cell lines.
Topics: Cell Line; Histamine Antagonists; Humans; Integrin beta1; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-6; Procollagen; Terfenadine; Tumor Cells, Cultured | 1998 |
Reply to Gonzalez and Estes.
Topics: Adult; Aged; Aging; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |
QT lengthening and arrhythmias associated with fexofenadine.
Topics: Aged; Arrhythmias, Cardiac; Electrocardiography; Histamine Antagonists; Humans; Risk Factors; Terfenadine | 1999 |
Pharmacokinetic aspects of second-generation H1 antihistamines: a reply to Philpot.
Topics: Administration, Oral; Area Under Curve; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine.
Topics: Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Genes, MDR; HeLa Cells; Histamine H1 Antagonists; Humans; LLC-PK1 Cells; Mice; Rats; Swine; Terfenadine; Tissue Distribution; Transfection; Vaccinia virus | 1999 |
QT lengthening and life-threatening arrhythmias associated with fexofenadine.
Topics: Aged; Electrocardiography; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Syncope; Tachycardia, Ventricular; Terfenadine; Ventricular Fibrillation | 1999 |
Causality assessment of adverse drug effects: when is rechallenge ethically acceptable?
Topics: Arrhythmias, Cardiac; Ethics, Medical; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |
Fexofenadine and prolonged QT intervals.
Topics: Aged; Drug Monitoring; Electrocardiography; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Terfenadine | 1999 |
A new synthesis of carboxyterfenadine (fexofenadine) and its bioisosteric tetrazole analogs.
Topics: Histamine H1 Antagonists; Humans; Magnetic Resonance Spectroscopy; Terfenadine | 1999 |
Prolonged QTc time and ventricular arrhythmia with fexofenadine.
Topics: Arrhythmias, Cardiac; Heart Conduction System; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |
Nonsedating antihistamines should be preferred over sedating antihistamines in patients who drive.
Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Terfenadine | 2000 |
Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria.
Topics: Administration, Oral; Adolescent; Adult; Anti-Allergic Agents; Chronic Disease; Dose-Response Relationship, Drug; Headache; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria | 2000 |
QT lengthening and life-threatening arrhythmias associated with fexofenadine.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Cohort Studies; Histamine H1 Antagonists; Humans; Terfenadine | 2000 |
Sedation with "non-sedating" antihistamines: four prescription-event monitoring studies in general practice.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Cetirizine; Child; Child, Preschool; Consciousness Disorders; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Loratadine; Male; Middle Aged; Product Surveillance, Postmarketing; Sleep Stages; Terfenadine; Triprolidine | 2000 |
The potential of active metabolites of antihistamines in the management of allergic disease.
Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases | 2000 |
Fexofenadine-induced QT prolongation: a myth or fact?
Topics: Controlled Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Long QT Syndrome; Terfenadine | 2000 |
In vitro studies with fexofenadine, a new nonsedating histamine H1 receptor antagonist, on isolated human basophils.
Topics: Basophils; Dermatitis, Atopic; Enzyme Inhibitors; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; Protein Kinase C; Terfenadine | 2000 |
Kinetics of injected histamine in cat plasma after antihistamine prophylaxis.
Topics: Animals; Cats; Cimetidine; Ethylenediamines; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Kinetics; Male; Terfenadine | 2000 |
Impact of interventions designed to increase market share and prescribing of fexofenadine at HMOs.
Topics: Analysis of Variance; Astemizole; Cetirizine; Cost Savings; Drug Costs; Drug Utilization; Health Maintenance Organizations; Histamine H1 Antagonists; Humans; Loratadine; Marketing of Health Services; Practice Patterns, Physicians'; Retrospective Studies; Terfenadine; United States | 2000 |
Drug effects on driving performance.
Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Research Design; Terfenadine | 2000 |
Drug effects on driving performance.
Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Research Design; Terfenadine | 2000 |
Drug effects on driving performance.
Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Research Design; Terfenadine | 2000 |
Fixed solar urticaria to visible light successfully treated with fexofenadine.
Topics: Anti-Allergic Agents; Female; Humans; Middle Aged; Sunlight; Terfenadine; Ultraviolet Rays; Urticaria | 2001 |
Uptake and efflux of the peptidic delta-opioid receptor agonist.
Topics: Analgesics, Opioid; Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Calcium Channel Blockers; Carrier Proteins; Digoxin; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; Estradiol; Histamine H1 Antagonists; Male; Mice; Mice, Knockout; Perfusion; Receptors, Opioid, delta; Terfenadine; Verapamil | 2001 |
[Multiple prevention. On the way to an ideal antihistamine?].
Topics: Histamine H1 Antagonists; Humans; Mast Cells; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2000 |
Hepatic disposition of fexofenadine: influence of the transport inhibitors erythromycin and dibromosulphothalein.
Topics: Animals; Area Under Curve; Bile; Biological Transport, Active; Erythromycin; Histamine H1 Antagonists; Liver; Male; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Terfenadine | 2000 |
Newer antihistamines.
Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine | 2001 |
Seldane approval may be withdrawn by FDA.
Topics: Drug Approval; Drug Interactions; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Perennial; Terfenadine; United States; United States Food and Drug Administration | 1997 |
[Seasonal allergic rhinitis. Nasal obstruction can also beh improved].
Topics: Anti-Allergic Agents; Double-Blind Method; Humans; Loratadine; Multicenter Studies as Topic; Nasal Obstruction; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Terfenadine | 2001 |
A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Databases as Topic; Drug Utilization Review; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Retrospective Studies; Rhinitis, Allergic, Perennial; Terfenadine; United States | 2001 |
Identification of functionally variant MDR1 alleles among European Americans and African Americans.
Topics: Africa; Alleles; Anti-Allergic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Black People; Cloning, Molecular; Digoxin; DNA Primers; Enzyme Inhibitors; Europe; Genes, MDR; Genetic Variation; Genotype; Haplotypes; Humans; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Terfenadine; Time Factors; White People | 2001 |
Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.
Topics: Anti-Allergic Agents; Health Services Accessibility; Humans; Insurance Carriers; Legislation, Drug; Loratadine; Nonprescription Drugs; Terfenadine; United States; United States Food and Drug Administration | 2001 |
Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997.
Topics: Adult; Anti-Allergic Agents; England; Family Practice; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Product Surveillance, Postmarketing; Terfenadine | 2001 |
The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Cetirizine; Child; Cohort Studies; Drug Costs; Economics, Pharmaceutical; Female; Health Care Costs; Histamine H1 Antagonists; Humans; Loratadine; Male; Managed Care Programs; Middle Aged; Retrospective Studies; Rhinitis, Allergic, Perennial; Terfenadine; United States | 2001 |
Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.
Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Humans; Lymphocytes; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Terfenadine | 2002 |
Determination of fexofenadine in human plasma and urine by liquid chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Mass Spectrometry; Terfenadine | 2002 |
[Comparative antihistamine and anti-allergic effects of various antihistamine preparations].
Topics: Adult; Anti-Allergic Agents; Butyrophenones; Cetirizine; Clemastine; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Male; Piperidines; Pollen; Terfenadine | 2002 |
[Hay fever and asthma. Many of your patients have both].
Topics: Asthma; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2002 |
Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.
Topics: Anti-Arrhythmia Agents; Cell Line; Dose-Response Relationship, Drug; Electric Conductivity; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Kinetics; Long QT Syndrome; Membrane Potentials; Mutation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Terfenadine | 2002 |
Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes.
Topics: Adult; Cell Count; Exercise; Female; Histamine H1 Antagonists; Humans; Hydroxyurea; Hypoxia; Inflammation Mediators; Leukotriene Antagonists; Leukotriene E4; Lung; Male; Oxygen Consumption; Pulmonary Gas Exchange; Respiratory Function Tests; Sports; Sputum; Terfenadine | 2002 |
Are herbal products dietary supplements or drugs? An important question for public safety.
Topics: Anti-Allergic Agents; Cardiovascular System; Ephedra; Histamine H1 Antagonists; Humans; Hypericum; Pharmacokinetics; Plant Extracts; Terfenadine; United States; United States Food and Drug Administration | 2002 |
Simultaneous determination of fexofenadine and its related compounds by HPLC.
Topics: Capsules; Chromatography, High Pressure Liquid; Drug Contamination; Drug Stability; Histamine H1 Antagonists; Sensitivity and Specificity; Tablets; Terfenadine | 2002 |
Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.
Topics: Adoptive Transfer; Allergens; Animals; Anti-Allergic Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Inflammation; Lung; Mice; Mice, Inbred BALB C; T-Lymphocytes; Terfenadine | 2002 |
Chronic urticaria and angioedema.
Topics: Angioedema; Chronic Disease; Histamine H1 Antagonists; Humans; Terfenadine; Urticaria | 2002 |
In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.
Topics: Adolescent; Adult; Biopsy, Needle; Case-Control Studies; Chronic Disease; Culture Techniques; E-Selectin; Female; Follow-Up Studies; Humans; Immunohistochemistry; Male; Middle Aged; Probability; Prospective Studies; Reference Values; Severity of Illness Index; Terfenadine; Treatment Outcome; Urticaria; Vascular Cell Adhesion Molecule-1 | 2002 |
Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.
Topics: Adrenergic beta-Antagonists; Bronchodilator Agents; Chromatography, Liquid; Ephedrine; Histamine H1 Antagonists; Humans; Leprostatic Agents; Metoprolol; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Rifampin; Robotics; Solvents; Spectrometry, Mass, Electrospray Ionization; Terfenadine | 2002 |
The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.
Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Base Sequence; Blotting, Western; Cation Transport Proteins; Cell Line; Colforsin; COS Cells; DNA; DNA Mutational Analysis; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Genotype; Histamine H1 Antagonists; Humans; Immunohistochemistry; Male; Membrane Potentials; Molecular Sequence Data; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Voltage-Gated; Pruritus; Sequence Homology, Amino Acid; Terfenadine; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Regulator ERG | 2002 |
Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Chromatography, High Pressure Liquid; Depression, Chemical; Drug Interactions; Drug Stability; Fluorometry; Histamine H1 Antagonists; Humans; In Vitro Techniques; Kinetics; Rhodamines; Ritonavir; Terfenadine; Time Factors; Verapamil | 2002 |
The use of antihistamines in safety-critical jobs: a meeting report.
Topics: Aviation; Cognition; Histamine H1 Antagonists; Humans; Occupational Diseases; Occupations; Rhinitis, Allergic, Seasonal; Safety; Seasons; Sleep Stages; Terfenadine | 2002 |
Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80.
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Female; Glucocorticoids; Histamine; Humans; Hypersensitivity, Immediate; Male; p-Methoxy-N-methylphenethylamine; Prednisolone; Skin Tests; Terfenadine | 2002 |
Facial swelling and eosinophilia in a 44-year-old woman.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Angioedema; Cefuroxime; Cetirizine; Diagnosis, Differential; Drug Hypersensitivity; Edema; Eosinophilia; Face; Fatigue; Female; Humans; Hypereosinophilic Syndrome; Indoles; Lansoprazole; Methylprednisolone; Methylprednisolone Acetate; Omeprazole; Penicillins; Phenylcarbamates; Prednisone; Ranitidine; Recurrence; Sulfonamides; Syndrome; Terfenadine; Tosyl Compounds | 2002 |
Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS.
Topics: Calibration; Chromatography, Liquid; Dapsone; Ephedrine; Isotope Labeling; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization; Terfenadine | 2003 |
The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.
Topics: Adult; Antifungal Agents; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Interactions; Female; Histamine H1 Antagonists; Humans; Intestinal Absorption; Jejunum; Ketoconazole; Male; Permeability; Terfenadine | 2003 |
Decongestant effects of antihistamines: a class effect?
Topics: Controlled Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Loratadine; Nasal Decongestants; Rhinitis, Allergic, Seasonal; Terfenadine | 2003 |
Solar urticaria induced by infrared radiation.
Topics: Female; Histamine H1 Antagonists; Humans; Infrared Rays; Middle Aged; PUVA Therapy; Terfenadine; Urticaria | 2003 |
[Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].
Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Receptors, Histamine H1; Terfenadine; Time Factors | 2003 |
Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.
Topics: Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Patient Satisfaction; Rhinitis, Allergic, Seasonal; Sleep Wake Disorders; Terfenadine; Treatment Outcome | 2003 |
Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.
Topics: Administration, Inhalation; Adoptive Transfer; Allergens; Animals; Anti-Allergic Agents; Antibody Specificity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Female; Histamine H1 Antagonists; Immunoglobulin E; Injections, Intraperitoneal; Leukocyte Count; Methacholine Chloride; Mice; Mice, Inbred BALB C; Ovalbumin; Respiratory Hypersensitivity; Rhinitis, Allergic, Perennial; T-Lymphocytes; Terfenadine; Time Factors; Treatment Outcome | 2003 |
Is 3-mm less drowsiness important?
Topics: Anti-Allergic Agents; Automobile Driving; Cetirizine; Humans; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sleep Stages; Terfenadine; Treatment Outcome | 2003 |
Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro.
Topics: Adult; Allergens; Antigens, Plant; Cell Division; Chemokine CCL17; Chemokines, CC; Dose-Response Relationship, Immunologic; Histamine H1 Antagonists; Humans; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Plant Proteins; Polymerase Chain Reaction; Rhinitis, Allergic, Seasonal; RNA, Messenger; Terfenadine | 2004 |
The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis.
Topics: Anaphylaxis; Animals; Antigens, Helminth; Chemokine CCL11; Chemokines, CC; Dose-Response Relationship, Drug; Endotoxins; Eosinophilia; Histamine H1 Antagonists; Interleukin-5; Intestine, Small; Male; Mast Cells; Mice; Species Specificity; Terfenadine; Trichinella spiralis; Trichinellosis | 2004 |
Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.
Topics: Anti-Allergic Agents; Cetirizine; Choice Behavior; Data Collection; Humans; Loratadine; Managed Care Programs; Nonprescription Drugs; Patient Satisfaction; Terfenadine; United States | 2004 |
Lack of association between fexofenadine and rhabdomyolysis.
Topics: Histamine H1 Antagonists; Humans; Rhabdomyolysis; Terfenadine; United States | 2004 |
Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.
Topics: Adult; Anti-Allergic Agents; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Flow Cytometry; Fluorescent Dyes; Genotype; Humans; Lymphocytes; Male; Mixed Function Oxygenases; Omeprazole; Rhodamine 123; Terfenadine | 2004 |
Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection.
Topics: Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Terfenadine | 2004 |
Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Spectrometry, Fluorescence; Terfenadine | 2004 |
A novel membrane sensor for histamine H1-receptor antagonist "fexofenadine".
Topics: Anti-Allergic Agents; Biosensing Techniques; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Ions; Membranes, Artificial; Molecular Structure; Solutions; Terfenadine; Time Factors | 2004 |
Transport characteristics of fexofenadine in the Caco-2 cell model.
Topics: ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Caco-2 Cells; Chromatography, High Pressure Liquid; Diffusion; Humans; Inhibitory Concentration 50; Kinetics; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Permeability; Terfenadine | 2004 |
Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine.
Topics: Absidia; Biotransformation; Butyrophenones; Cunninghamella; Histamine H1 Antagonists; Oxidation-Reduction; Piperidines; Streptomyces griseus; Terfenadine | 2004 |
Suppressive activity of fexofenadine hydrochloride on the production of eosinophil chemoattractants from human nasal fibroblasts in vitro.
Topics: Cells, Cultured; Chemokine CCL5; Chemokines; Chemotactic Factors; Eosinophils; Fibroblasts; Histamine H1 Antagonists; Humans; Lipopolysaccharides; Nasal Mucosa; Nasal Polyps; RNA, Messenger; Terfenadine | 2004 |
The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride.
Topics: Administration, Oral; Adult; Age Factors; Analysis of Variance; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Humans; Infant; Male; Models, Biological; Rhinitis, Allergic, Seasonal; Sex Factors; Terfenadine | 2004 |
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.
Topics: Adult; Alleles; Area Under Curve; Exons; Female; Gene Frequency; Genes, MDR; Genetic Variation; Genotype; Haplotypes; Histamine H1 Antagonists; Humans; Korea; Male; Polymorphism, Genetic; Terfenadine | 2004 |
Effect of fruit juices on the oral bioavailability of fexofenadine in rats.
Topics: Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Beverages; Biological Availability; Citrus; Food-Drug Interactions; Fruit; Histamine H1 Antagonists; Intestinal Absorption; Male; Malus; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; Terfenadine | 2005 |
Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro.
Topics: Adult; Cells, Cultured; Depression, Chemical; Female; Fibroblasts; Histamine H1 Antagonists; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloproteases; Nasal Mucosa; Terfenadine; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2004 |
Preferential downmodulation of certain chemokines by fexofenadine in human keratinocytes.
Topics: Cell Line; Chemokines; Down-Regulation; Histamine H1 Antagonists; Humans; Keratinocytes; Terfenadine | 2005 |
P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Blood-Brain Barrier; Histamine H1 Antagonists; Intestine, Small; Male; Mice; Mice, Knockout; Rats; Rats, Mutant Strains; Terfenadine | 2005 |
Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).
Topics: Area Under Curve; Heterozygote; Histamine H1 Antagonists; Humans; Liver-Specific Organic Anion Transporter 1; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Polymorphism, Genetic; Terfenadine | 2005 |
Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Clinical Trials, Phase III as Topic; Data Interpretation, Statistical; Dermatology; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Pruritus; Quality of Life; Self Disclosure; Severity of Illness Index; Sickness Impact Profile; Surveys and Questionnaires; Terfenadine; Urticaria | 2005 |
Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.
Topics: Cell Line; Estradiol; Estrone; Histamine H1 Antagonists; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Organic Anion Transport Protein 1; Sincalide; Terfenadine | 2005 |
Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Area Under Curve; Carbazoles; Disease Models, Animal; Guinea Pigs; Indoles; Leukotrienes; Male; Ovalbumin; Phenylcarbamates; Pyrilamine; Rhinitis; Sulfonamides; Terfenadine; Thromboxanes; Tosyl Compounds | 2005 |
Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer.
Topics: Anti-Allergic Agents; Biological Transport; Cell Membrane Permeability; Cell Polarity; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Electric Impedance; Epithelial Cells; Humans; Nasal Mucosa; Terfenadine; Time Factors | 2005 |
The advantages of the Ussing chamber in drug absorption studies.
Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Cell Membrane; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Jejunum; Ketoconazole; Kinetics; Mass Spectrometry; Permeability; Protein Binding; Rats; Terfenadine; Time Factors | 2005 |
Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.
Topics: Cetirizine; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine; Treatment Outcome; Urticaria | 2005 |
Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets.
Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Solubility; Tablets, Enteric-Coated; Terfenadine | 2005 |
Determination of fexofenadine in tablets by capillary electrophoresis in free solution and in solution with cyclodextrins as analyte carriers.
Topics: Anti-Allergic Agents; beta-Cyclodextrins; Chemistry, Pharmaceutical; Drug Carriers; Electrolytes; Electrophoresis, Capillary; Histamine H1 Antagonists; Tablets; Terfenadine | 2005 |
Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.
Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Arachidonic Acid; Cells, Cultured; Dinoprostone; Histamine H1 Antagonists; Humans; Leukotrienes; Lipopolysaccharides; Monocytes; Terfenadine; Zymosan | 2006 |
Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.
Topics: Animals; Cetirizine; CHO Cells; Cricetinae; Cricetulus; Histamine H1 Antagonists; Humans; Loratadine; Piperazines; Predictive Value of Tests; Receptors, Histamine H1; Recombination, Genetic; Terfenadine; Urticaria | 2005 |
Treatment of ear pain in pilots in flight.
Topics: Aerospace Medicine; Anti-Allergic Agents; Humans; Loratadine; Pain; Rhinitis, Allergic, Seasonal; Steroids; Terfenadine | 2005 |
The methanol disolvate and the dihydrate of fexofenadine, an antihistamine drug.
Topics: Crystallography, X-Ray; Histamine H1 Antagonists, Non-Sedating; Hydrogen Bonding; Methanol; Models, Molecular; Molecular Conformation; Molecular Structure; Solubility; Terfenadine | 2005 |
The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; E-Selectin; Female; Histamine H1 Antagonists; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Male; Olopatadine Hydrochloride; Substance P; Terfenadine; Vascular Cell Adhesion Molecule-1 | 2005 |
[Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].
Topics: Administration, Oral; Adult; Aspirin; Cromolyn Sodium; Exercise; Female; Humans; Radioallergosorbent Test; Skin Tests; Terfenadine; Wheat Hypersensitivity | 2005 |
Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.
Topics: Anti-Allergic Agents; Biological Transport, Active; Chromatography, Liquid; Drug Interactions; Humans; Kidney; Kinetics; Mass Spectrometry; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Probenecid; Renal Agents; Terfenadine | 2006 |
Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate.
Topics: Adenosine Triphosphatases; Animals; Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autoradiography; Biological Transport, Active; Brain; Chromatography, Liquid; Intestinal Absorption; Kinetics; LLC-PK1 Cells; Male; Mass Spectrometry; Mice; Mice, Knockout; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Swine; Terfenadine; Verapamil | 2006 |
Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.
Topics: Animals; Antiparasitic Agents; Area Under Curve; Biological Availability; Drug Interactions; Female; Half-Life; Histamine H1 Antagonists; Horses; Ivermectin; Terfenadine | 2006 |
Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata.
Topics: Adolescent; Adult; Aged; Alopecia Areata; Cohort Studies; Cyclopropanes; Dermatitis, Contact; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Histamine H1 Antagonists; Humans; Male; Middle Aged; Prospective Studies; Pruritus; Risk Assessment; Severity of Illness Index; Terfenadine; Treatment Outcome | 2006 |
First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.
Topics: Animals; Antipyrine; Bile; Calcium Channel Blockers; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Intestinal Absorption; Liver; Models, Animal; Perfusion; Swine; Terfenadine; Verapamil | 2006 |
Pustular exacerbation of psoriasis due to fexofenadine.
Topics: Acute Disease; Drug Eruptions; Histamine H1 Antagonists; Humans; Male; Middle Aged; Psoriasis; Terfenadine | 2006 |
Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes.
Topics: Animals; Bile; Biotransformation; Cell Separation; Cells, Cultured; Chromatography, High Pressure Liquid; Hepatocytes; Histamine H1 Antagonists; Liver; Male; Mass Spectrometry; Models, Statistical; Pharmaceutical Preparations; Protein Binding; Rats; Rats, Wistar; Terfenadine | 2006 |
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.
Topics: Animals; Benzimidazoles; Bradykinin; Bronchial Spasm; Capillary Permeability; Cetirizine; Dermatitis; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Hypersensitivity; Male; Mice; Molecular Structure; Oxazolone; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H1; Serotonin; Structure-Activity Relationship; Terfenadine; Time Factors | 2006 |
Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cardiotonic Agents; Chromatography, Liquid; Digoxin; Genistein; Half-Life; Histamine H1 Antagonists; Injections, Intravenous; Male; Mass Spectrometry; Paclitaxel; Rats; Rats, Sprague-Dawley; Terfenadine | 2006 |
Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biliary Tract; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Injections, Intraperitoneal; Kinetics; Lipopolysaccharides; Liver; Male; Metabolic Clearance Rate; Organic Anion Transporters; Perfusion; Rats; Rats, Sprague-Dawley; Terfenadine | 2006 |
Saliva secretion in patients with allergic rhinitis.
Topics: Adolescent; Adult; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Middle Aged; Patient Satisfaction; Pilot Projects; Rhinitis; Saliva; Salivary Glands; Terfenadine; Xerostomia | 2006 |
Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs.
Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Citric Acid; Cough; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Histamine H1 Antagonists, Non-Sedating; Male; Purinergic P2 Receptor Antagonists; Receptors, Histamine H1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reflex; Terfenadine | 2006 |
Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis.
Topics: Administration, Oral; Adult; Amino Acids; Anti-Asthmatic Agents; Biopsy; Colitis, Ulcerative; Colonoscopy; Cromolyn Sodium; Drug Therapy, Combination; Follow-Up Studies; Glucocorticoids; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Remission Induction; Terfenadine | 2007 |
Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.
Topics: Commerce; Cost-Benefit Analysis; Cross-Sectional Studies; Delivery of Health Care; Drug Prescriptions; Histamine H1 Antagonists, Non-Sedating; Humans; Israel; Loratadine; Marketing of Health Services; Terfenadine | 2006 |
Transporter-mediated intestinal absorption of fexofenadine in rats.
Topics: Animals; Anti-Allergic Agents; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane Permeability; Dose-Response Relationship, Drug; Estrone; Intestinal Absorption; Ketoconazole; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; Terfenadine; Xenopus | 2006 |
Simultaneous quantification of fexofenadine and pseudoephedrine in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: method development, validation and application to a clinical study.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Complex Mixtures; Ephedrine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Terfenadine | 2006 |
Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer.
Topics: Cell Membrane Permeability; Cell Survival; Drug Synergism; Epithelial Cells; Formazans; Histamine H1 Antagonists, Non-Sedating; Humans; Microscopy, Confocal; Nasal Mucosa; Poloxamer; Polysorbates; Sodium Cholate; Surface-Active Agents; Taurocholic Acid; Terfenadine; Tetrazolium Salts | 2007 |
New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.
Topics: Animals; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Sheep; Terfenadine | 2006 |
QT interval prolongation and beyond.
Topics: Animals; Anti-Allergic Agents; Dogs; Electrocardiography; Heart Rate; Humans; Long QT Syndrome; Terfenadine | 2006 |
The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.
Topics: Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Cyproheptadine; Electrophysiology; Histamine H1 Antagonists; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Membrane Potentials; Microscopy, Confocal; Myocytes, Cardiac; Patch-Clamp Techniques; Sarcoplasmic Reticulum; Terfenadine | 2006 |
Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys.
Topics: Animals; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Liver; Macaca fascicularis; Male; Microsomes; Midazolam; Terfenadine | 2007 |
Ultrarush venom desensitization after systemic reactions during conventional venom immunotherapy.
Topics: Adult; Anti-Allergic Agents; Desensitization, Immunologic; Female; Humans; Hypersensitivity, Immediate; Prednisolone; Ranitidine; Terfenadine; Wasp Venoms | 2006 |
Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.
Topics: Benzamides; Chromatography, High Pressure Liquid; Drug Stability; Humans; Morpholines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Terfenadine | 2007 |
Pharmacokinetics of fexofenadine enantiomers in healthy subjects.
Topics: Adult; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Stereoisomerism; Terfenadine | 2007 |
Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Asthmatic Agents; Butyrophenones; Cetirizine; Conjunctivitis, Allergic; Cromolyn Sodium; Diabetes Mellitus, Type 1; Heart; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Piperazines; Piperidines; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.
Topics: Cells, Cultured; Cetirizine; Dibenzoxepins; Histamine H1 Antagonists, Non-Sedating; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-4; Interleukin-5; Loratadine; Olopatadine Hydrochloride; RNA, Messenger; T-Lymphocytes; Terfenadine | 2007 |
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Rats; Rats, Wistar; Seizures; Terfenadine; Time Factors | 2007 |
Simple and reliable HPLC analysis of fexofenadine hydrochloride in tablets and its application to dissolution studies.
Topics: Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Reference Standards; Reproducibility of Results; Solubility; Spectrophotometry, Ultraviolet; Tablets; Terfenadine | 2007 |
[Treatment of allergic rhinitis associated with hypothyroidism].
Topics: Adult; Anti-Allergic Agents; Female; Humans; Hypothyroidism; Immunoglobulins; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
Formaldehyde-induced urticarial vasculitis.
Topics: Adult; Drug Therapy, Combination; Formaldehyde; Glucocorticoids; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Occupational Exposure; Prednisolone; Serum Sickness; Students, Medical; Terfenadine; Urticaria; Vasculitis, Leukocytoclastic, Cutaneous | 2007 |
Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation.
Topics: Calibration; Chromatography, High Pressure Liquid; Drug Combinations; Histamine H1 Antagonists, Non-Sedating; Least-Squares Analysis; Molecular Structure; Nasal Decongestants; Pseudoephedrine; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Terfenadine; Time Factors | 2007 |
Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Anti-Allergic Agents; Calibration; Chromatography, Liquid; Humans; Molecular Structure; Randomized Controlled Trials as Topic; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Terfenadine | 2007 |
Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry.
Topics: Atmospheric Pressure; Humans; Molecular Weight; Particle Size; Plant Leaves; Plant Roots; Plant Stems; Proteins; Reserpine; Seedlings; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Tagetes; Terfenadine; Verapamil | 2007 |
Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression Regulation; Histamine H1 Antagonists, Non-Sedating; Hypersensitivity; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Nasal Polyps; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger; Terfenadine; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.
Topics: Animals; Bile; Histamine H1 Antagonists, Non-Sedating; Liver; Male; Membrane Transport Proteins; Metabolic Clearance Rate; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats; Rats, Inbred Strains; Species Specificity; Terfenadine | 2008 |
Fexofenadine downmodulates antigen-presenting ability of murine epidermal Langerhans cells.
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Down-Regulation; Epidermal Cells; Langerhans Cells; Mice; Mice, Inbred BALB C; Terfenadine | 2008 |
Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.
Topics: Administration, Inhalation; Animals; Antigens, Fungal; Antitussive Agents; Aspergillus; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Citric Acid; Cough; Dose-Response Relationship, Drug; Fungal Proteins; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Male; Methacholine Chloride; Respiratory Hypersensitivity; Terfenadine | 2008 |
Isolation and structure elucidation of photodegradation products of fexofenadine.
Topics: Histamine H1 Antagonists; Molecular Structure; Photochemistry; Spectrophotometry, Ultraviolet; Terfenadine | 2008 |
Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis.
Topics: Adolescent; Anaphylaxis; Anti-Asthmatic Agents; Cold Temperature; Cromolyn Sodium; Drug Therapy, Combination; Exercise; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Pruritus; Swimming; Terfenadine; Treatment Outcome; Triticum; Urticaria; Water; Wheat Hypersensitivity | 2007 |
[Linear dermatitis due to shiitake mushrooms].
Topics: Administration, Oral; Administration, Topical; Adult; Androstadienes; Anti-Allergic Agents; Dermatitis, Atopic; Drug Therapy, Combination; Fluticasone; Food Hypersensitivity; Humans; Hypersensitivity, Immediate; Male; Shiitake Mushrooms; Terfenadine | 2007 |
Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Dosage Forms; Histamine H1 Antagonists; Pharmaceutical Preparations; Pseudoephedrine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Terfenadine | 2008 |
Fexofenadine/cyclodextrin inclusion complexation: phase solubility, thermodynamic, physicochemical, and computational analysis.
Topics: Calorimetry, Differential Scanning; Cyclodextrins; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Osmolar Concentration; Solubility; Terfenadine; Thermodynamics; X-Ray Diffraction | 2007 |
Two cases of alopecia areata responsive to fexofenadine.
Topics: Adult; Aged; Alopecia Areata; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine | 2007 |
Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans.
Topics: Animals; Biological Transport; Cell Line; Dogs; Drug Interactions; Humans; Liver; Pharmaceutical Preparations; Terfenadine | 2008 |
Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cell Line; Dogs; Gene Expression Regulation; Glutathione; Humans; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Quinolines; Recombinant Proteins; Terfenadine | 2008 |
Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.
Topics: Animals; Bile; Histamine H1 Antagonists, Non-Sedating; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Terfenadine | 2008 |
Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Dogs; Female; Intestinal Absorption; Loperamide; Male; Mutation; Quinidine; Terfenadine | 2008 |
Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Child, Preschool; Data Collection; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Europe; Female; Histamine H1 Antagonists; Humans; Infant; Male; Middle Aged; Patient Satisfaction; Piperazines; Prevalence; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Urticaria | 2008 |
Relative contribution of absorptive and secretory transporters to the intestinal absorption of fexofenadine in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Dose-Response Relationship, Drug; Duodenum; Histamine H1 Antagonists, Non-Sedating; Ileum; Intestinal Absorption; Jejunum; Male; Organic Anion Transporters; Permeability; Rats; Rats, Wistar; Terfenadine | 2008 |
A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorescence; Rats; Reproducibility of Results; Terfenadine | 2008 |
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniramine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Imidazoles; Japan; Male; Middle Aged; Olopatadine Hydrochloride; Pain Measurement; Piperidines; Population Surveillance; Psychomotor Performance; Pyridines; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Surveys and Questionnaires; Terfenadine; Urticaria | 2008 |
Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.
Topics: Administration, Oral; Animals; Antirheumatic Agents; Area Under Curve; Azithromycin; Biological Transport, Active; Cell Line; Clarithromycin; Dogs; Histamine H1 Antagonists, Non-Sedating; Infusions, Intravenous; Intestinal Absorption; Male; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Rifamycins; Taurocholic Acid; Terfenadine; Transfection | 2008 |
Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.
Topics: Algorithms; Animals; Biological Transport, Active; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Diffusion; Estrone; Fatty Acids, Monounsaturated; Fluvastatin; Hepatocytes; Indoles; Kinetics; Male; Membranes, Artificial; Models, Biological; Naphthalenes; Oligopeptides; Organic Anion Transporters; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Piperidines; Quinolines; Rats; Rats, Wistar; Sincalide; Temperature; Terfenadine | 2008 |
Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.
Topics: Animals; Antipyrine; Catheterization; Cost-Benefit Analysis; Femoral Artery; Hematocrit; Jugular Veins; Male; Pharmacokinetics; Quinidine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Surgical Procedures, Operative; Terfenadine; Time Factors; Triazoles | 2008 |
The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.
Topics: Cell Line; Cimetidine; Drug Interactions; Humans; Kidney; Organic Cation Transport Proteins; Probenecid; Terfenadine | 2009 |
Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Mice; Terfenadine | 2009 |
IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model.
Topics: Animals; Anti-Allergic Agents; Carbazoles; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Interleukin-16; Mice; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Platelet Aggregation Inhibitors; Rhinitis, Allergic, Perennial; Sulfonamides; Terfenadine | 2009 |
Multiple H1-antihistamine-induced urticaria.
Topics: Administration, Oral; Adult; Drug Eruptions; Female; Histamine; Histamine H1 Antagonists; Humans; Immunologic Tests; Leukotriene B4; Loratadine; Piperidines; Pyridines; Skin Tests; Terfenadine; Urticaria | 2009 |
Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry.
Topics: Animals; Biological Availability; Histamine H1 Antagonists, Non-Sedating; Intestinal Mucosa; Liver; Male; Mice; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Terfenadine; Tissue Distribution | 2008 |
N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a "chemical knock-out equivalent" to assess the impact of efflux transporters on oral drug absorption in the rat.
Topics: Animals; Anti-Allergic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estradiol; Hypnotics and Sedatives; Intestinal Absorption; Isoquinolines; Male; Midazolam; Pharmaceutical Preparations; Prazosin; Quinazolines; Rats; Rats, Sprague-Dawley; Sympatholytics; Terfenadine | 2009 |
Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.
Topics: Animals; Area Under Curve; Chromatography, High Pressure Liquid; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Histamine H1 Antagonists; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Intestinal Absorption; Male; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; Terfenadine | 2009 |
Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.
Topics: Animals; Biliary Tract; Cells, Cultured; Histamine H1 Antagonists, Non-Sedating; Humans; Liver; Models, Biological; Molecular Probes; Rats; Rats, Wistar; Terfenadine | 2009 |
Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Alopecia Areata; Child; Child, Preschool; Cyclobutanes; Cyclopropanes; Dermatologic Agents; Female; Humans; Hypersensitivity; Immunotherapy; Male; Middle Aged; Retrospective Studies; Terfenadine; Young Adult | 2009 |
Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics.
Topics: Diagnosis, Differential; Glucocorticoids; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Hysteroscopy; Male; Mast Cells; Mastocytosis, Systemic; Middle Aged; Physical Examination; Prednisolone; Ranitidine; Terfenadine; Tomography, X-Ray Computed; Treatment Outcome; Ureteral Calculi; Urolithiasis | 2009 |
Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study.
Topics: Adolescent; Adult; Chromatography, Liquid; Female; Fractional Precipitation; Histamine H1 Antagonists, Non-Sedating; Humans; Linear Models; Male; Proteins; Sensitivity and Specificity; Tandem Mass Spectrometry; Terfenadine; Young Adult | 2010 |
Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo.
Topics: Animals; Anti-Allergic Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Male; Mass Spectrometry; Metabolic Clearance Rate; Panax; Plant Preparations; Random Allocation; Rats; Rats, Sprague-Dawley; Terfenadine; Time Factors | 2009 |
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizine; Drug Interactions; Female; Guinea Pigs; Histamine H1 Antagonists, Non-Sedating; Hydroxyzine; Hypersensitivity; Immunoglobulin G; Interleukin-4; Leukocytes; Loratadine; Male; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Nasal Mucosa; Pentobarbital; Piperazines; Sneezing; Terfenadine | 2010 |
ESRD impairs nonrenal clearance of fexofenadine but not midazolam.
Topics: Adult; Aged; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Urea Nitrogen; Cytochrome P-450 CYP3A; Enterocytes; Female; Hepatocytes; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Organic Anion Transporters; Prospective Studies; Rats; Rats, Sprague-Dawley; Terfenadine | 2009 |
Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Hepatocytes; Histamine H1 Antagonists, Non-Sedating; Hypericum; Liver; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Terfenadine | 2009 |
Efficacy of repeated pretreatment with olopatadine hydrochloride on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Dibenzoxepins; Disease Models, Animal; Drug Administration Schedule; Histamine H1 Antagonists, Non-Sedating; Male; Nerve Growth Factor; Olopatadine Hydrochloride; Rats; Rats, Inbred BN; Rhinitis, Allergic, Seasonal; Terfenadine; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A | 2009 |
Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.
Topics: Biological Transport; Caco-2 Cells; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Membrane Permeability; Diffusion; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Esters; Humans; Intestinal Absorption; Nitrophenols; Prodrugs; Propranolol; Terfenadine | 2010 |
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Cetirizine; Child; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Ketotifen; Leukotriene Antagonists; Loratadine; Piperazines; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Safety; Sulfides; Tablets; Terfenadine; Treatment Outcome | 2009 |
[Administration of premedication with fexofenadine for paclitaxel-induced hypersensitive reactions in breast cancer patients complicated with closed-angle glaucoma].
Topics: Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Hypersensitivity; Female; Glaucoma, Angle-Closure; Humans; Middle Aged; Paclitaxel; Premedication; Terfenadine | 2010 |
Allergies in India: a study on medication compliance.
Topics: Adolescent; Adult; Anti-Allergic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Ethanolamines; Female; Formoterol Fumarate; Humans; Immunoglobulin E; India; Male; Patient Compliance; Rhinitis, Allergic, Perennial; Skin Tests; Spirometry; Terfenadine; Treatment Outcome; Urticaria | 2009 |
Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antigens, Plant; Artemisia; Betula; Disease Progression; Eosinophil Cationic Protein; Female; Histamine; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Leukotriene D4; Male; Middle Aged; Nasal Lavage Fluid; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2009 |
Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Area Under Curve; Biological Availability; Cell Line; Drug Carriers; Electric Impedance; Epithelial Cells; Humans; Hyaluronic Acid; Microscopy, Electron, Scanning; Microspheres; Particle Size; Permeability; Polyethylene Glycols; Rabbits; Respiratory Mucosa; Surface Properties; Taurocholic Acid; Terfenadine | 2010 |
Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction.
Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodioxoles; Biological Availability; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Food-Drug Interactions; Gastric Emptying; Half-Life; Histamine H1 Antagonists, Non-Sedating; Intestinal Absorption; Male; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Terfenadine | 2010 |
Melt-in-mouth pellets of fexofenadine hydrochloride using crospovidone as an extrusion-spheronisation aid.
Topics: Administration, Oral; Anti-Allergic Agents; Capsules; Drug Compounding; Drug Stability; Excipients; Mouth; Povidone; Solubility; Terfenadine | 2010 |
Preparation and evaluation of fexofenadine microemulsions for intranasal delivery.
Topics: Administration, Intranasal; Administration, Oral; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Compounding; Emulsions; Glycerides; Glycols; Histamine H1 Antagonists, Non-Sedating; Injections, Intravenous; Male; Nasal Mucosa; Oils; Organic Chemicals; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Technology, Pharmaceutical; Terfenadine; Viscosity | 2010 |
Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
Topics: Animals; Bile Acids and Salts; Bilirubin; Female; Liver; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rifampin; Terfenadine | 2010 |
Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Intranasal; Animals; beta-Cyclodextrins; Cell Membrane Permeability; Cells, Cultured; Chitosan; Gels; Histamine H1 Antagonists, Non-Sedating; Humans; Poloxamer; Rabbits; Temperature; Terfenadine; Viscosity | 2011 |
A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonoids; Humans; Quantitative Structure-Activity Relationship; Rabbits; Terfenadine | 2010 |
20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Digoxin; Etoposide; Ginsenosides; Herb-Drug Interactions; Humans; Ileum; Male; Rats; Rats, Sprague-Dawley; Rhodamine 123; Terfenadine; Verapamil | 2010 |
Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers.
Topics: Adult; Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Female; Humans; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Polymorphism, Genetic; Stereoisomerism; Terfenadine; Young Adult | 2010 |
Pharmacokinetics of fexofenadine following LPS administration to rats.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Biological Availability; Inflammation; Injections, Intravenous; Lipopolysaccharides; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Terfenadine | 2010 |
Regional absorption of fexofenadine in rat intestine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Colon; Cyclosporins; Histamine H1 Antagonists, Non-Sedating; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; RNA, Messenger; Terfenadine | 2010 |
The relationship between the drug concentration profiles in plasma and the drug doses in the colon.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Area Under Curve; Biological Availability; Colon; Delayed-Action Preparations; Diclofenac; Diltiazem; Dogs; Dose-Response Relationship, Drug; Hypoglycemic Agents; Metformin; Muscarinic Agonists; Quinuclidines; Terfenadine; Thiophenes; Verapamil | 2010 |
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extracellular Signal-Regulated MAP Kinases; GATA1 Transcription Factor; Gene Expression; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Macrophages; Male; Middle Aged; NF-kappa B; Phosphorylation; Phthalazines; Piperazines; Plant Proteins; Rhinitis, Allergic, Seasonal; Signal Transduction; Terfenadine; Tuberculin; Young Adult | 2011 |
Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.
Topics: Animals; Anti-Anxiety Agents; Dermatitis, Atopic; Drugs, Chinese Herbal; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Histamine H1 Antagonists, Non-Sedating; Immunohistochemistry; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sex Factors; Signal Transduction; Skin; Social Isolation; Terfenadine | 2011 |
Urticaria due to antihistamines.
Topics: Administration, Oral; Butyrophenones; Diagnosis, Differential; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Middle Aged; Piperidines; Terfenadine; Urticaria | 2011 |
Buspirone, fexofenadine, and omeprazole: quantification of probe drugs and their metabolites in human plasma.
Topics: Buspirone; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, Liquid; Humans; Models, Chemical; Omeprazole; Quality Control; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Terfenadine | 2011 |
Evaluation of the genotoxicity and cytotoxicity of fexofenadine in cultured human peripheral blood lymphocytes.
Topics: Cell Nucleus Division; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Lymphocytes; Male; Micronucleus Tests; Mitotic Index; Molecular Structure; Terfenadine; Toxicity Tests; Young Adult | 2011 |
In brief: fexofenadine (Allegra) and fruit juice.
Topics: Beverages; Food-Drug Interactions; Fruit; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine | 2011 |
Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus.
Topics: Acetylcholine; Animals; Attention; Cholinesterase Inhibitors; Cimetidine; Dimaprit; Electroencephalography; Hippocampus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Hypoxia, Brain; In Vitro Techniques; Male; Microelectrodes; Physostigmine; Pyramidal Tracts; Rats; Rats, Wistar; Terfenadine | 2011 |
Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry.
Topics: Cell Extracts; Cetirizine; Chromatography, Liquid; HEK293 Cells; Humans; Least-Squares Analysis; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Terfenadine | 2011 |
Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Cell Polarity; Dogs; Enterocytes; Histamine H1 Antagonists, Non-Sedating; Humans; Intestinal Absorption; Kidney Tubules, Distal; Membrane Transport Modulators; Models, Biological; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Prodrugs; Protein Transport; Recombinant Proteins; Terfenadine | 2011 |
Development of a novel high-throughput analytical methodology, multiple injection method, for quantitative analysis in drug metabolism and pharmacokinetic studies using liquid chromatography with tandem mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Imipramine; Male; Ondansetron; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Risperidone; Tandem Mass Spectrometry; Terfenadine; Validation Studies as Topic; Verapamil | 2011 |
In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Dose-Response Relationship, Drug; Electric Impedance; Histamine H1 Antagonists, Non-Sedating; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Models, Biological; Permeability; Rats; Rats, Wistar; Sodium Dodecyl Sulfate; Solubility; Surface-Active Agents; Terfenadine | 2012 |
Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations.
Topics: Buffers; Chemistry, Pharmaceutical; Etodolac; Europium; Hydrogen-Ion Concentration; Reproducibility of Results; Spectrometry, Fluorescence; Terfenadine; Tetrahydroisoquinolines; Tromethamine | 2012 |
Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Caco-2 Cells; Drug Delivery Systems; Drug Stability; Emulsions; Half-Life; Humans; Oleic Acid; Permeability; Rabbits; Solubility; Terfenadine; Water | 2011 |
Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.
Topics: Algorithms; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Drug Interactions; Erythromycin; Gene Expression; Glycerol; Humans; Intestinal Absorption; Loperamide; Models, Biological; Pharmaceutical Preparations; Propanolamines; Puromycin; Quinidine; Saquinavir; Solubility; Surface-Active Agents; Terfenadine; Verapamil; Vinblastine | 2011 |
Assessment of fexofenadine hydrochloride permeability and dissolution with an anionic surfactant using Caco-2 cells.
Topics: Algorithms; Caco-2 Cells; Chromatography, High Pressure Liquid; Electric Impedance; Epithelium; Histamine H1 Antagonists, Non-Sedating; Humans; Permeability; Sodium Dodecyl Sulfate; Solubility; Spectrometry, Fluorescence; Surface-Active Agents; Terfenadine | 2011 |
Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.
Topics: Animals; Autoradiography; Histocytochemistry; Histocytological Preparation Techniques; Liquid-Liquid Extraction; Male; Mass Spectrometry; Mice; Reproducibility of Results; Sensitivity and Specificity; Terfenadine; Tissue Distribution | 2011 |
The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cetirizine; Chromatography, High Pressure Liquid; Drug Interactions; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Loratadine; Mass Spectrometry; Permeability; Terfenadine | 2012 |
Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters?
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Binding, Competitive; Blood-Brain Barrier; Corpus Striatum; Drug Therapy, Combination; Humans; Injections, Intramuscular; Ketoconazole; Male; Neoplasm Proteins; Pituitary Gland; Positron-Emission Tomography; Psychotic Disorders; Receptors, Dopamine D2; Risperidone; Schizophrenia; Terfenadine | 2012 |
Preseasonal prophylactic treatment with antihistamines suppresses IL-5 but not IL-33 mRNA expression in the nasal mucosa of patients with seasonal allergic rhinitis caused by Japanese cedar pollen.
Topics: Butyrophenones; Cryptomeria; Female; Histamine Antagonists; Humans; Interleukin-33; Interleukin-5; Interleukins; Male; Middle Aged; Nasal Mucosa; Piperidines; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine | 2012 |
Fluorodeoxyglucose-induced allergic reaction: a case report.
Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Carcinoma, Squamous Cell; Diphenhydramine; Drug Hypersensitivity; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Prednisone; Pyriform Sinus; Radiopharmaceuticals; Secondary Prevention; Squamous Cell Carcinoma of Head and Neck; Terfenadine; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch.
Topics: Adult; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperidines; Pruritus; Pyridines; Skin; Terfenadine; Urticaria | 2012 |
Treatment of acquired perforating dermatosis with cantharidin.
Topics: Aged; Anti-Allergic Agents; Cantharidin; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Keratolytic Agents; Kidney Failure, Chronic; Nicotinic Acids; Peritoneal Dialysis; Skin Diseases; Terfenadine | 2012 |
Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.
Topics: alpha-Cyclodextrins; Histamine Antagonists; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Molecular Structure; Solubility; Solutions; Terfenadine; Water | 2012 |
Enhanced systemic exposure of fexofenadine via the intranasal administration of chitosan-coated liposome.
Topics: Adhesiveness; Administration, Intranasal; Administration, Oral; Adsorption; Animals; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Cholesterol; Delayed-Action Preparations; Dimyristoylphosphatidylcholine; Drug Compounding; Histamine H1 Antagonists, Non-Sedating; Injections, Intravenous; Lipids; Liposomes; Male; Mucins; Nanoparticles; Particle Size; Phosphatidylglycerols; Rats; Rats, Sprague-Dawley; Surface Properties; Technology, Pharmaceutical; Terfenadine | 2012 |
Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin A in rats.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Antifungal Agents; Cyclosporine; Gene Expression Regulation; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Intestines; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; RNA, Messenger; Terfenadine | 2012 |
Case of intractable ophiasis type of alopecia areata presumably improved by fexofenadine.
Topics: Adult; Alopecia Areata; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine; Young Adult | 2012 |
Effect of intestinal first-pass hydrolysis on the oral bioavailability of an ester prodrug of fexofenadine.
Topics: Administration, Oral; Animals; Biological Availability; Biotransformation; Chemistry, Pharmaceutical; Enterocytes; Histamine H1 Antagonists, Non-Sedating; Hydrolases; Hydrolysis; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Jejunum; Liver; Male; Prodrugs; Protein Binding; Rats; Rats, Wistar; Technology, Pharmaceutical; Terfenadine | 2012 |
The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats.
Topics: Age Factors; Animals; Anti-Allergic Agents; Brain; Caffeine; Central Nervous System Stimulants; Dibenzoxepins; Electroshock; Epilepsy; GABA Antagonists; Histamine H1 Antagonists; Ketotifen; Male; Olopatadine Hydrochloride; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Terfenadine | 2012 |
Development of a highly sensitive methodology for quantitative determination of fexofenadine in a microdose study by multiple injection method using ultra-high performance liquid chromatography with tandem mass spectrometry.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Terfenadine | 2012 |
Enhancement of clara cell 10-kD protein (CC10) production from nasal epithelial cells by fexofenadine hydrochloride.
Topics: Adult; Cells, Cultured; Cryptomeria; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Histamine H1 Antagonists; Humans; Male; Middle Aged; Nasal Cavity; Pollen; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Terfenadine; Tumor Necrosis Factor-alpha; Uteroglobin | 2012 |
Analysis of the pharmacokinetic boosting effects of ritonavir on oral bioavailability of drugs in mice.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Female; HIV Protease Inhibitors; Inactivation, Metabolic; Mice; Microsomes; Midazolam; Pravastatin; Ritonavir; Saquinavir; Terfenadine | 2013 |
Exploring novel colon-targeting antihistaminic prodrug for colitis.
Topics: Amides; Animals; Colitis, Ulcerative; Colon; Glucosamine; Histamine Antagonists; Liver; Male; Pancreas; Prodrugs; Rats; Rats, Wistar; Stomach; Terfenadine; Trinitrobenzenesulfonic Acid | 2012 |
Enantioselective uptake of fexofenadine by Caco-2 cells as model intestinal epithelial cells.
Topics: Adenosine Triphosphate; Anti-Allergic Agents; Binding, Competitive; Biological Transport, Active; Caco-2 Cells; Enterocytes; Histamine H1 Antagonists, Non-Sedating; Humans; Intestinal Absorption; Kinetics; Membrane Transport Modulators; Organic Anion Transporters; Proton Ionophores; Stereoisomerism; Terfenadine; Uncoupling Agents | 2013 |
Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption.
Topics: Absorption; Animals; Beverages; Binding Sites; Binding, Competitive; Biological Transport; Citrus paradisi; Citrus sinensis; Estrone; Food-Drug Interactions; Fruit; Kinetics; Malus; Oocytes; Organic Anion Transporters; Terfenadine; Xenopus laevis | 2013 |
You're the flight surgeon: nasal congestion and Eustachian tube dysfunction.
Topics: Adult; Aerospace Medicine; Desensitization, Immunologic; Eustachian Tube; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Military Personnel; Rhinitis, Allergic, Perennial; Terfenadine | 2013 |
Application of in-line near infrared spectroscopy and multivariate batch modeling for process monitoring in fluid bed granulation.
Topics: Humidity; Models, Theoretical; Multivariate Analysis; Particle Size; Spectroscopy, Near-Infrared; Technology, Pharmaceutical; Temperature; Terfenadine | 2013 |
In vivo assessment of the impact of efflux transporter on oral drug absorption using portal vein-cannulated rats.
Topics: Absorption; Adenosine; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catheterization; Dibenzocycloheptenes; Diketopiperazines; Heterocyclic Compounds, 4 or More Rings; Male; Portal Vein; Quinolines; Rats; Rats, Sprague-Dawley; Sulfasalazine; Terfenadine; Topotecan | 2013 |
Improved oral bioavailability of fexofenadine hydrochloride using lipid surfactants: ex vivo, in situ and in vivo studies.
Topics: Administration, Oral; Animals; Biological Availability; Calorimetry, Differential Scanning; Drug Carriers; Intestinal Absorption; Lipids; Male; Permeability; Polyethylene Glycols; Rats; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Terfenadine; Vitamin E | 2014 |
Simultaneous determination of montelukast and fexofenadine using Fourier transform convolution emission data under non- parametric linear regression method.
Topics: Acetates; Calibration; Cyclopropanes; Linear Models; Quinolines; Spectroscopy, Fourier Transform Infrared; Sulfides; Terfenadine | 2013 |
Stress-induced visceral hypersensitivity in maternally separated rats can be reversed by peripherally restricted histamine-1-receptor antagonists.
Topics: Animals; Blotting, Western; Butyrophenones; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Irritable Bowel Syndrome; Mast Cells; Maternal Deprivation; Occludin; Piperidines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological; Terfenadine | 2013 |
The role of multidrug resistance-1 (MDR1) variants in response to fexofenadine among Jordanians.
Topics: Adult; Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Humans; Jordan; Male; Multivariate Analysis; Polymorphism, Single Nucleotide; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sex Characteristics; Terfenadine | 2013 |
Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs.
Topics: Animals; Bile; Biological Transport; Biotransformation; Chromatography, Liquid; Drug Interactions; Hepatobiliary Elimination; Infusions, Intravenous; Kidney; Liver; Male; Models, Biological; Swine; Tandem Mass Spectrometry; Terfenadine; Verapamil | 2014 |
Thin layer chromatography-densitometric determination of some non-sedating antihistamines in combination with pseudoephedrine or acetaminophen in synthetic mixtures and in pharmaceutical formulations.
Topics: Acetaminophen; Chromatography, Thin Layer; Densitometry; Histamine H1 Antagonists, Non-Sedating; Limit of Detection; Linear Models; Loratadine; Pseudoephedrine; Reproducibility of Results; Tablets; Terfenadine | 2014 |
Flare-up reaction after creeping disease.
Topics: Aged; Anti-Allergic Agents; Antiparasitic Agents; Humans; Ivermectin; Male; Skin Diseases, Parasitic; Terfenadine | 2013 |
Efficacy of fexofenadine in isolated rat tracheas.
Topics: Animals; Electric Stimulation; Histamine H1 Antagonists, Non-Sedating; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Rats; Terfenadine; Tissue Culture Techniques; Trachea | 2013 |
How should we handle decreased efficacy caused by DDI on transporters for drug absorption and target-tissue distribution, but not associated with toxicity?
Topics: Beverages; Drug Interactions; Fruit; Humans; Intestinal Absorption; Organic Anion Transporters; Terfenadine; Tissue Distribution | 2013 |
Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bupropion; Caffeine; Calibration; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dextromethorphan; Dried Blood Spot Testing; Flurbiprofen; Half-Life; Male; Midazolam; Omeprazole; Pharmaceutical Preparations; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2014 |
Phenylalanine-free taste-masked orodispersible tablets of fexofenadine hydrochloride: development, in vitro evaluation and in vivo estimation of the drug pharmacokinetics in healthy human volunteers.
Topics: Administration, Oral; Adult; Alginates; Anti-Allergic Agents; Chitosan; Excipients; Glucuronic Acid; Hexuronic Acids; Humans; Male; Phenylalanine; Tablets; Taste; Taste Perception; Terfenadine; Young Adult | 2015 |
Idiopathic pure sudomotor failure responding to oral antihistamine with sweating activities.
Topics: Administration, Oral; Adult; Autonomic Nervous System Diseases; Biopsy; Histamine H1 Antagonists, Non-Sedating; Humans; Hypohidrosis; Male; Sweating; Terfenadine; Treatment Outcome | 2014 |
Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B1.
Topics: Animals; Beverages; Binding Sites; Cells, Cultured; Citrus paradisi; Dose-Response Relationship, Drug; Female; Food-Drug Interactions; Oocytes; Organic Anion Transporters; Pravastatin; Substrate Specificity; Terfenadine; Xenopus laevis | 2014 |
Geneva cocktail for cytochrome p450 and P-glycoprotein activity assessment using dried blood spots.
Topics: Administration, Oral; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bupropion; Caffeine; Capsules; Carbonated Beverages; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Coffee; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dried Blood Spot Testing; Enzyme Inhibitors; Feasibility Studies; Flurbiprofen; Humans; Isoenzymes; Male; Midazolam; Omeprazole; Pharmaceutical Preparations; Phenotype; Pilot Projects; Predictive Value of Tests; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine; Young Adult | 2014 |
[Establishment of reverse-phase high-performance liquid chromatography with chiral reagent derivatization for separation of fexofenadine enantiomers].
Topics: Chromatography, High Pressure Liquid; Stereoisomerism; Terfenadine | 2014 |
H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biomarkers; Cetirizine; Cholesterol Esters; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Histamine H1 Antagonists; Lipogenesis; Liver; Liver-Specific Organic Anion Transporter 1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organic Anion Transporters, Sodium-Independent; Severity of Illness Index; Terfenadine; Triglycerides | 2014 |
Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.
Topics: Analysis of Variance; Animals; Apolipoproteins E; Atherosclerosis; Blood Chemical Analysis; CD36 Antigens; Cetirizine; Cholesterol, LDL; Diet, High-Fat; Disease Progression; Fluorescent Antibody Technique; Histamine H1 Antagonists; Male; Mast Cells; Mice; Mice, Knockout; Nitric Oxide Synthase; Signal Transduction; Terfenadine | 2014 |
Application of the BCS biowaiver approach to assessing bioequivalence of orally disintegrating tablets with immediate release formulations.
Topics: Administration, Oral; Animals; Biopharmaceutics; Chemistry, Pharmaceutical; Dibenzoxepins; Droxidopa; Famotidine; Humans; Hydrochlorothiazide; Olopatadine Hydrochloride; Pharmaceutical Vehicles; Tablets; Terfenadine; Therapeutic Equivalency | 2014 |
Determination of fexofenadine in Hank's balanced salt solution by high-performance liquid chromatography with ultraviolet detection: application to Caco-2 cell permeability studies.
Topics: Caco-2 Cells; Cells; Chromatography, High Pressure Liquid; Culture Media; Humans; Membrane Transport Proteins; Permeability; Terfenadine | 2015 |
Pruritic eruption on the chest.
Topics: Acantholysis; Acneiform Eruptions; Administration, Oral; Administration, Topical; Biopsy; Clobetasol; Dermatitis, Seborrheic; Dermatologic Agents; Diagnosis, Differential; Drug Eruptions; Folliculitis; Histamine Antagonists; Humans; Ichthyosis; Male; Middle Aged; Skin; Terfenadine; Treatment Outcome | 2014 |
Using improved serial blood sampling method of mice to study pharmacokinetics and drug-drug interaction.
Topics: Administration, Intravenous; Administration, Oral; Animals; Antipyrine; Biological Availability; Blood Specimen Collection; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Monitoring; Ibuprofen; Male; Mice, Inbred C57BL; Models, Animal; Organic Anion Transporters; Pravastatin; Reproducibility of Results; Rifampin; Tail; Terfenadine; Triazoles; Veins | 2015 |
Effect of CKD and dialysis modality on exposure to drugs cleared by nonrenal mechanisms.
Topics: Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Anti-Anxiety Agents; Cytochrome P-450 CYP3A; Female; Humans; Kidney; Male; Midazolam; Middle Aged; Peritoneal Dialysis; Renal Dialysis; Renal Insufficiency, Chronic; Severity of Illness Index; Terfenadine | 2015 |
Fexofenadine regulates nuclear factor-κB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in mice.
Topics: Acute Disease; Animals; Chronic Disease; Colitis; Endoplasmic Reticulum Stress; Female; HCT116 Cells; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Terfenadine | 2015 |
Myocardial infarction associated with eosinophilia and plasma extravasation at multiple sites. A variant of Kounis syndrome.
Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Eosinophilia; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Male; Methylprednisolone; Myocardial Infarction; Plasma; Rhinitis, Allergic; Syndrome; Terfenadine | 2015 |
The determination of crystal structures of active pharmaceutical ingredients from X-ray powder diffraction data: a brief, practical introduction, with fexofenadine hydrochloride as example.
Topics: Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Humans; Hydrogen Bonding; Molecular Structure; Pharmaceutical Preparations; Powder Diffraction; Powders; Reproducibility of Results; Solvents; Terfenadine; X-Rays | 2015 |
[Sex differences of P-glycoprotein functional activity and expression in rabbits].
Topics: Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Gene Expression; Half-Life; Histamine H1 Antagonists, Non-Sedating; Intestinal Mucosa; Intestines; Liver; Male; Rabbits; Sex Factors; Terfenadine | 2014 |
Effect of diosmin on the intestinal absorption and pharmacokinetics of fexofenadine in rats.
Topics: Administration, Oral; Animals; Biological Availability; Diosmin; Drug Interactions; Intestinal Absorption; Male; Permeability; Propranolol; Rats; Terfenadine | 2015 |
Carbopol-incorporated thermoreversible gel for intranasal drug delivery.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Acrylates; Adhesiveness; Administration, Intranasal; Animals; beta-Cyclodextrins; Biological Availability; Drug Delivery Systems; Gels; Histamine H1 Antagonists, Non-Sedating; Poloxamer; Rabbits; Rheology; Terfenadine; Tissue Distribution; Viscosity | 2015 |
Paroxetine decreased plasma exposure of glyburide partly via inhibiting intestinal absorption in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Biological Transport; Caco-2 Cells; Drug Interactions; Drug Therapy, Combination; Feces; Flavanones; Glyburide; Humans; Hypoglycemic Agents; Intestinal Absorption; Male; Microsomes, Liver; Organic Anion Transporters, Sodium-Independent; Paroxetine; Rats, Sprague-Dawley; Terfenadine | 2015 |
Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data.
Topics: Budesonide; Colon; Cyclosporine; Fenofibrate; Humans; Intestinal Absorption; Intestinal Mucosa; Lisdexamfetamine Dimesylate; Metoprolol; Nifedipine; Pyrimidines; Ranitidine; Rivastigmine; Sumatriptan; Terfenadine; Theophylline | 2015 |
Design of Fexofenadine Prodrugs Based on Tissue-Specific Esterase Activity and Their Dissimilar Recognition by P-Glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carboxylic Ester Hydrolases; Cell Line; Cell Membrane Permeability; Esterases; HEK293 Cells; Humans; Hydrolysis; Intestinal Absorption; Intestine, Small; LLC-PK1 Cells; Prodrugs; Swine; Terfenadine | 2015 |
Impact of fexofenadine, osthole and histamine on peripheral blood mononuclear cell proliferation and cytokine secretion.
Topics: Adult; Cell Proliferation; Cells, Cultured; Coumarins; Cytokines; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Interleukin-10; Interleukin-6; Leukocytes, Mononuclear; Male; Terfenadine; Time Factors; Tumor Necrosis Factor-alpha | 2015 |
Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity.
Topics: Acetates; Adolescent; Adult; Cetirizine; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Photosensitivity Disorders; Quinolines; Remission Induction; Remission, Spontaneous; Severity of Illness Index; Sulfides; Sunlight; Terfenadine; Ultraviolet Rays; Urticaria; Young Adult | 2015 |
Generalized pruritus in primary sclerosing cholangitis: implications of histamine release by lysophosphatidic acid.
Topics: Adolescent; Cholangitis, Sclerosing; Histamine H1 Antagonists, Non-Sedating; Histamine Release; Humans; Lysophospholipids; Male; Pruritus; Terfenadine | 2015 |
Histamine 1 Receptor Blockade Enhances Eosinophil-Mediated Clearance of Adult Filarial Worms.
Topics: Animals; Cimetidine; Cytokines; Eosinophils; Female; Filariasis; Filarioidea; Gene Expression Regulation; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Receptors, Histamine H1; Sex Ratio; Spleen; Terfenadine | 2015 |
Expression of Carboxylesterase Isozymes and Their Role in the Behavior of a Fexofenadine Prodrug in Rat Skin.
Topics: Administration, Cutaneous; Animals; Carboxylesterase; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Male; Organ Culture Techniques; Prodrugs; Rats; Rats, Wistar; Skin Absorption; Terfenadine | 2016 |
The Interesting Case of Acyclovir Delivered Using Chitosan in Humans: Is it a Drug Issue or Formulation Issue?
Topics: Acyclovir; Adhesiveness; Administration, Oral; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Excipients; Humans; Intestinal Absorption; Permeability; Terfenadine | 2016 |
Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency.
Topics: Action Potentials; Berberine; Caveolin 1; Cell Membrane; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Kinetics; Mutation; Phenylalanine; Potassium Channel Blockers; Resveratrol; RNA Interference; Stilbenes; Terfenadine; Transfection; Tyrosine | 2015 |
HPLC Determination of Fexofenadine in Human Plasma For Therapeutic Drug Monitoring and Pharmacokinetic Studies.
Topics: Adult; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Histamine H1 Antagonists, Non-Sedating; Humans; Quality Control; Terfenadine; Young Adult | 2016 |
Recommended Daily Dose of Sesame Lignans Has No Influence on Oral Absorption of P-Glycoprotein Substrates in Rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Dioxoles; Drug Interactions; Food-Drug Interactions; Humans; Intestinal Absorption; Lignans; Male; Plant Extracts; Rats, Wistar; Rhodamine 123; Seeds; Sesamum; Terfenadine | 2015 |
Simultaneous quantitation of Ofloxacin, Fexofenadine HCl and Diclofenac Potassium in affixed dose combinative formulation by HPLC-UV method.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diclofenac; Drug Combinations; Histamine H1 Antagonists, Non-Sedating; Ofloxacin; Reproducibility of Results; Spectrophotometry, Ultraviolet; Terfenadine | 2015 |
Unique case of postural cholinergic urticaria induced by a standing position.
Topics: Acetylcholine; Adolescent; Diphenhydramine; Humans; Male; Posture; Terfenadine; Urticaria | 2016 |
Effect of resveratrol on the pharmacokinetics of fexofenadine in rats: Involvement of P-glycoprotein inhibition.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Drug Interactions; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Permeability; Rats; Rats, Wistar; Resveratrol; Stilbenes; Terfenadine; Verapamil | 2016 |
Localized heat urticaria: Positive reaction of preheated autologous serum skin test.
Topics: Anaphylaxis; Chlorpheniramine; Desensitization, Immunologic; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Hot Temperature; Humans; Influenza, Human; Intradermal Tests; Male; Middle Aged; Serum; Skin; Terfenadine; Urticaria | 2016 |
Oxidation of cetirizine, fexofenadine and hydrochlorothiazide during ozonation: Kinetics and formation of transformation products.
Topics: Cetirizine; Chromatography, Liquid; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Ozone; Tandem Mass Spectrometry; Terfenadine; Wastewater; Water Pollutants, Chemical; Water Purification | 2016 |
Binding of fexofenadine hydrochloride to bovine serum albumin: structural considerations by spectroscopic techniques and molecular docking.
Topics: Animals; Binding Sites; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Serum Albumin, Bovine; Spectrum Analysis; Terfenadine; Thermodynamics | 2017 |
Transcatheter aortic valve implantation with the NVT Allegra transcatheter heart valve system: first-in-human experience with a novel self-expanding transcatheter heart valve.
Topics: Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Cardiac Catheterization; Female; Heart Valve Prosthesis; Humans; Male; Patient Selection; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2016 |
Effect of fermented red ginseng on cytochrome P450 and P-glycoprotein activity in healthy subjects, as evaluated using the cocktail approach.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Drug Interactions; Fermented Foods; Healthy Volunteers; Humans; Losartan; Male; Midazolam; Middle Aged; Omeprazole; Panax; Pharmaceutical Preparations; Terfenadine; Young Adult | 2016 |
Cosmetic tattoo pigment reaction.
Topics: Adult; Anti-Allergic Agents; Coloring Agents; Cosmetic Techniques; Facial Dermatoses; Female; Glucocorticoids; Humans; Lymphocytes; Prednisone; Skin; Tattooing; Terfenadine | 2016 |
Cytokine production by PBMC and serum from allergic and non-allergic subjects following in vitro histamine stimulation to test fexofenadine and osthole anti-allergic properties.
Topics: Adult; Anti-Allergic Agents; Coumarins; Cytokines; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Leukocytes, Mononuclear; Male; Terfenadine | 2016 |
Changes in gene expression induced by histamine, fexofenadine and osthole: Expression of histamine H
Topics: Adult; Case-Control Studies; Chemokine CCL5; Coumarins; Cyclooxygenase 2; Female; Gene Expression Regulation; Histamine; Humans; Hypersensitivity; Interleukin-1beta; Leukocytes, Mononuclear; Male; NF-kappa B; Receptors, Histamine H1; RNA, Messenger; Terfenadine | 2017 |
Investigating Drug Repositioning Approach to Design Novel Prodrugs for Colon-specific Release of Fexofenadine for Ulcerative Colitis.
Topics: Animals; Colitis, Ulcerative; Colon; Drug Liberation; Drug Repositioning; Prodrugs; Rats; Rats, Wistar; Terfenadine | 2017 |
The influence of piperine on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy volunteers.
Topics: Adult; Alkaloids; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodioxoles; Biological Availability; Half-Life; Healthy Volunteers; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperidines; Polyunsaturated Alkamides; Terfenadine | 2017 |
Reply to "Comment on 'In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models'".
Topics: Biopharmaceutics; Computer Simulation; Gastrointestinal Agents; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Pharmaceutical Preparations; Terfenadine | 2017 |
Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H
Topics: Animals; Aspartic Acid; Cations, Monovalent; Chlorpheniramine; CHO Cells; Cricetulus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Ligands; Mutation; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Histamine H1; Sodium Chloride; Terfenadine | 2017 |
Influence of P-glycoprotein on the disposition of fexofenadine and its enantiomers.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Dogs; Fluorescence; Stereoisomerism; Terfenadine | 2017 |
Capsaicin pretreatment enhanced the bioavailability of fexofenadine in rats by P-glycoprotein modulation: in vitro, in situ and in vivo evaluation.
Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Capsaicin; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Intestinal Absorption; Male; Perfusion; Permeability; Propranolol; Rats; Rats, Wistar; Terfenadine | 2017 |
Effect of Garlic, Gingko, and St. John's Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Interactions; Garlic; Ginkgo biloba; Hypericum; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Organic Anion Transporters, Sodium-Independent; Perfusion; Plant Extracts; Rats; Substrate Specificity; Terfenadine; Tissue Distribution | 2017 |
CYP3A4 Activity is Markedly Lower in Patients with Crohn's Disease.
Topics: Adult; Aged; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Case-Control Studies; Crohn Disease; Cytochrome P-450 CYP3A; Female; Follow-Up Studies; Humans; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Prognosis; Substrate Specificity; Terfenadine | 2017 |
Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism.
Topics: Action Potentials; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; ERG1 Potassium Channel; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Lysosomes; Myocytes, Cardiac; Oxides; Patch-Clamp Techniques; Proteolysis; Resveratrol; Stilbenes; Terfenadine | 2017 |
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Induced by Fexofenadine.
Topics: Anti-Allergic Agents; Drug Hypersensitivity; Female; Humans; Middle Aged; Skin Tests; Stevens-Johnson Syndrome; Terfenadine | 2017 |
Fexofenadine Suppresses Delayed-Type Hypersensitivity in the Murine Model of Palladium Allergy.
Topics: Allergens; Animals; Anti-Allergic Agents; Antigen-Presenting Cells; Biomarkers; Cytokines; Disease Models, Animal; Edema; Female; Histamine H1 Antagonists, Non-Sedating; Hypersensitivity, Delayed; Mice; Palladium; Prednisolone; Signal Transduction; T-Lymphocyte Subsets; Terfenadine | 2017 |
A Method for Decreasing the Amount of the Drug Remaining on the Surfaces of the Mortar and Pestle after Grinding Small Amount of Tablets.
Topics: Adsorption; Calcium Phosphates; Drug Compounding; Excipients; Lactose; Mannitol; Powders; Tablets; Terfenadine | 2017 |
Sorption of citalopram, irbesartan and fexofenadine in soils: Estimation of sorption coefficients from soil properties.
Topics: Adsorption; Agriculture; Aluminum Silicates; Biphenyl Compounds; Citalopram; Clay; Irbesartan; Soil; Soil Pollutants; Terfenadine; Tetrazoles; Wastewater | 2018 |
Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Availability; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Curcumin; Cytochrome P-450 CYP3A; Female; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Lapatinib; Macaca fascicularis; Male; Midazolam; Neoplasm Proteins; Pantoprazole; Quinazolines; Rosuvastatin Calcium; Sulfasalazine; Terfenadine | 2018 |
Effects of antihistamines on the H295R steroidogenesis - Autocrine up-regulation following 3β-HSD inhibition.
Topics: 3-Hydroxysteroid Dehydrogenases; Autocrine Communication; Cell Line; Cell Survival; Cetirizine; Enzyme Inhibitors; Gene Expression Regulation; Histamine Antagonists; Histamine H1 Antagonists; Humans; Promethazine; Real-Time Polymerase Chain Reaction; Steroids; Terfenadine; Up-Regulation | 2018 |
Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsa
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Cross-Over Studies; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Halothane; Heart Rate; Myocardial Contraction; Risk; Terfenadine | 2018 |
IDENTIFICATION AND DETERMINATION OF RUPATADINE AND FEXOFENADINE BY DENSITOMETRIC METHOD.
Topics: Cyproheptadine; Densitometry; Histamine H1 Antagonists; Limit of Detection; Reproducibility of Results; Terfenadine | 2016 |
A case of food-dependent exercise-induced angioedema.
Topics: Adult; Allergens; Angioedema; Animals; Asthma, Exercise-Induced; Cattle; Diet Therapy; Female; Humans; Immunoglobulin E; Milk Hypersensitivity; Milk Proteins; Skin Tests; Terfenadine | 2019 |
Population histamine burden assessed using wastewater-based epidemiology: The association of 1,4‑methylimidazole acetic acid and fexofenadine.
Topics: Australia; Histamine Antagonists; Imidazoles; Terfenadine; Wastewater; Water Pollutants, Chemical | 2018 |
The long duration of action of the second generation antihistamine bilastine coincides with its long residence time at the histamine H
Topics: Benzimidazoles; Diphenhydramine; HeLa Cells; Histamine H1 Antagonists, Non-Sedating; Humans; Piperidines; Receptors, Histamine H1; Terfenadine; Time Factors | 2018 |
LC-MS/MS analysis of the plasma concentrations of a cocktail of 5 cytochrome P450 and P-glycoprotein probe substrates and their metabolites using subtherapeutic doses.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; Biological Variation, Population; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Healthy Volunteers; Humans; Isoenzymes; Losartan; Male; Metoprolol; Midazolam; Omeprazole; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Terfenadine | 2019 |
Effect of the Fexofenadine on the expression of HRH-1 and HRH-4 receptor in Peripheral Blood Mononuclear Cell isolated from children with diagnosed allergy - in vitro study Short communication.
Topics: Anti-Allergic Agents; Cells, Cultured; Child; Child, Preschool; Female; Gene Expression Regulation; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Leukocytes, Mononuclear; Male; Receptors, Histamine H1; Receptors, Histamine H4; Terfenadine | 2019 |
Transfermoral aortic valve implantation using self-expanding New Valve Technology (NVT) Allegra bioprosthesis: A pilot prospective study.
Topics: Aftercare; Aged; Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Female; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Patient Discharge; Prospective Studies; Prosthesis Design; Technology; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2021 |
The Allegra transcatheter heart valve: European multicentre experience with a novel self-expanding transcatheter aortic valve.
Topics: Aortic Valve; Aortic Valve Stenosis; Heart Valve Prosthesis; Humans; Prosthesis Design; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2019 |
Nasal Symptoms Reduction and Decreased Neutrophilia in Japanese Cedar Pollinosis With Prophylactic Treatment With a Combination of Montelukast, Fexofenadine, and Fluticasone Nasal Spray.
Topics: Acetates; Adult; Anti-Allergic Agents; Cetirizine; Cryptomeria; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Mast Cells; Middle Aged; Nasal Cavity; Nasal Sprays; Neutrophils; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Terfenadine; Treatment Outcome | 2019 |
Real-life experience in the treatment of solar urticaria: retrospective cohort study.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cohort Studies; Cyclopropanes; Disease Management; Female; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Omalizumab; Photosensitivity Disorders; Quinolines; Retrospective Studies; Sulfides; Terfenadine; Urticaria; Young Adult | 2019 |
Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors.
Topics: Animals; Cyproheptadine; Histamine; Histamine Agonists; Histamine Antagonists; Mucous Membrane; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Swine; Terfenadine; Urinary Bladder; Urothelium | 2019 |
Elephantiasis nostras verrucosa secondary to scleroderma.
Topics: Anti-Bacterial Agents; Bandages; Biopsy; Cephalexin; Dermatologic Agents; Doxepin; Elephantiasis; Female; Humans; Methotrexate; Middle Aged; Mupirocin; Mycophenolic Acid; PUVA Therapy; Scleroderma, Systemic; Skin; Skin Cream; Terfenadine; Treatment Outcome | 2019 |
A novel concept of immunological and allergy interactions in autism spectrum disorders: Molecular, anti-inflammatory effect of osthole.
Topics: Anti-Inflammatory Agents; Autism Spectrum Disorder; Child; Child, Preschool; Coumarins; Cyclooxygenase 2; Female; Histamine; Histamine Antagonists; Humans; Hypersensitivity; Infant; Leukocytes, Mononuclear; Male; Terfenadine | 2019 |
Fexofenadine and Rosuvastatin Pharmacokinetics in Mice with Targeted Disruption of Organic Anion Transporting Polypeptide 2B1.
Topics: Administration, Intravenous; Administration, Oral; Animals; Area Under Curve; Food-Drug Interactions; Fruit and Vegetable Juices; HEK293 Cells; HeLa Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Mice, Knockout; Organic Anion Transporters; Rosuvastatin Calcium; Terfenadine | 2019 |
Insect bites as a trigger factor of eosinophilic cellulitis.
Topics: Adolescent; Cellulitis; Eosinophilia; Female; Humans; Insect Bites and Stings; Terfenadine | 2019 |
Idiopathic postprandial diarrhea responsive to antihistamines.
Topics: Adult; Angioedema; Cetirizine; Diarrhea; Famotidine; Female; Food Hypersensitivity; Histamine Antagonists; Humans; Male; Middle Aged; Postprandial Period; Ranitidine; Terfenadine; Urticaria | 2019 |
Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis.
Topics: Animals; Arthritis, Experimental; Mice; Mice, Inbred DBA; Mice, Transgenic; Phospholipases A2, Cytosolic; Signal Transduction; Terfenadine; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2019 |
Bergamottin can be used to assess CYP3A-mediated intestinal first-pass metabolism without affecting P-glycoprotein-mediated efflux in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Buspirone; Cytochrome P-450 CYP3A; Furocoumarins; Liver; Male; Rats; Terfenadine | 2020 |
Elevated YKL-40 serum levels in patients with chronic spontaneous urticaria.
Topics: Antigens, CD; Cadherins; Cell Line; Cetirizine; Chitinase-3-Like Protein 1; Chronic Urticaria; Histamine Antagonists; Humans; Mast Cells; Terfenadine | 2019 |
Rituximab desensitization in two patients with muscle-specific kinase myasthenia gravis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Autoantibodies; Desensitization, Immunologic; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydrocortisone; Immunologic Factors; Infusions, Intravenous; Myasthenia Gravis; Premedication; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic; Rituximab; Terfenadine | 2019 |
NVT ALLEGRA transcatheter heart valve for valve-in-valve procedures in failing surgical aortic bioprostheses: let us wait and see.
Topics: Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Cardiac Catheterization; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Heart Valves; Humans; Prosthesis Design; Prosthesis Failure; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2019 |
Biological transformation of fexofenadine and sitagliptin by carrier-attached biomass and suspended sludge from a hybrid moving bed biofilm reactor.
Topics: Biofilms; Biomass; Bioreactors; Chromatography, Liquid; Sewage; Sitagliptin Phosphate; Tandem Mass Spectrometry; Terfenadine | 2019 |
Impact of implant depth on hydrodynamic function of the ALLEGRA bioprosthesis in valve-in-valve interventions.
Topics: Aortic Valve; Bioprosthesis; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Hemodynamics; Hydrodynamics; Prosthesis Design; Prosthesis Failure; Terfenadine; Transcatheter Aortic Valve Replacement | 2020 |
Clinical Findings Associated with Ornithodoros brasiliensis Tick Parasitism in Travelers, Southern Brazil.
Topics: Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Brazil; Dermatitis; Dexamethasone; Female; Humans; Male; Middle Aged; Ornithodoros; Terfenadine; Tick Bites; Travel; Young Adult | 2019 |
Potential synergistic effects of novel hematopoietic prostaglandin D synthase inhibitor TAS-205 and different types of anti-allergic medicine on nasal obstruction in a Guinea pig model of experimental allergic rhinitis.
Topics: Acetates; Animals; Anti-Allergic Agents; Cell Line; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Guinea Pigs; Humans; Intramolecular Oxidoreductases; Lipocalins; Male; Morpholines; Nasal Mucosa; Nasal Obstruction; Ovalbumin; Piperidines; Prostaglandin D2; Pyrroles; Quality of Life; Quinolines; Rats; Rhinitis, Allergic; Sulfides; Terfenadine | 2020 |
Organic anion transporting polypeptide 2B1 (OATP2B1), an expanded substrate profile, does it align with OATP2B1's hypothesized function?
Topics: Coproporphyrins; Humans; Intestinal Absorption; Organic Anion Transporters; Terfenadine | 2020 |
Direct chiral LC-MS/MS analysis of fexofenadine enantiomers in plasma and urine with application in a maternal-fetal pharmacokinetic study.
Topics: Adult; Anti-Allergic Agents; Chromatography, High Pressure Liquid; Female; Humans; Plasma; Pregnancy; Stereoisomerism; Tandem Mass Spectrometry; Terfenadine; Urine; Young Adult | 2020 |
Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End-Stage Renal Disease.
Topics: Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Drug Interactions; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Midazolam; Middle Aged; Organic Anion Transporters; Prospective Studies; Renal Dialysis; Renal Elimination; Terfenadine; Time Factors; Treatment Outcome | 2020 |
Evaluation of the Effects of Maytenus ilicifolia on the Activities of Cytochrome P450 3A and P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Ketoconazole; Male; Maytenus; Midazolam; Plant Extracts; Quinolines; Rats; Rats, Wistar; Terfenadine | 2020 |
Association Between Fexofenadine Use During Pregnancy and Fetal Outcomes.
Topics: Adult; Female; Follow-Up Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Infant, Newborn; Infant, Small for Gestational Age; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Premature Birth; Prenatal Care; Propensity Score; Retrospective Studies; Terfenadine; Young Adult | 2020 |
Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria.
Topics: Adolescent; Bangladesh; Chronic Disease; Chronic Urticaria; Double-Blind Method; Humans; Terfenadine; Treatment Outcome; Urticaria | 2020 |
Short-chain fatty acids exert opposite effects on the expression and function of p-glycoprotein and breast cancer resistance protein in rat intestine.
Topics: Acetates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Butyrates; Caco-2 Cells; Histone Deacetylase Inhibitors; Humans; Intestinal Mucosa; Male; Mice, Inbred BALB C; NF-kappa B; PPAR gamma; Propionates; Rats, Sprague-Dawley; Rosuvastatin Calcium; Signal Transduction; Terfenadine | 2021 |
Chiral Discrimination of P-glycoprotein in Parturient Women: Effect of Fluoxetine on Maternal-Fetal Fexofenadine Pharmacokinetics.
Topics: Adult; Antidepressive Agents, Second-Generation; ATP Binding Cassette Transporter, Subfamily B; Case-Control Studies; Drug Interactions; Female; Fetal Blood; Fluoxetine; Histamine H1 Antagonists, Non-Sedating; Humans; Intestinal Absorption; Intestinal Mucosa; Maternal-Fetal Exchange; Parturition; Placental Circulation; Pregnancy; Terfenadine; Young Adult | 2020 |
Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives.
Topics: Animals; Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Azo Compounds; Bacteria; Excipients; Female; Food; Food Additives; Gastrointestinal Microbiome; Histamine H1 Antagonists, Non-Sedating; Humans; Intestinal Absorption; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Organic Anion Transporters; Terfenadine | 2020 |
Urticaria and angioedema as a prodromal cutaneous manifestation of SARS-CoV-2 (COVID-19) infection.
Topics: Angioedema; Anti-Allergic Agents; Betacoronavirus; Chlorpheniramine; Coronavirus Infections; COVID-19; Diagnosis, Differential; Female; Humans; Middle Aged; Pandemics; Pneumonia, Viral; Prednisone; Prodromal Symptoms; SARS-CoV-2; Terfenadine; Treatment Outcome; Urticaria | 2020 |
Competitive and synergic sorption of carbamazepine, citalopram, clindamycin, fexofenadine, irbesartan and sulfamethoxazole in seven soils.
Topics: Adsorption; Carbamazepine; Citalopram; Clindamycin; Irbesartan; Soil; Soil Pollutants; Sulfamethoxazole; Terfenadine | 2020 |
Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data.
Topics: Acetamides; Albuterol; Animals; Carbamates; Chromatography, Liquid; Diazepam; Diclofenac; Digitoxin; Humans; Itraconazole; Ketoprofen; Liver; Metabolic Clearance Rate; Mice; Mice, Transgenic; Naproxen; Pharmaceutical Preparations; Phenytoin; Piperidines; Pravastatin; Pyrimidines; Quinidine; Tandem Mass Spectrometry; Telmisartan; Terfenadine; Verapamil | 2020 |
Eosinophilic gastroenteritis treated with a targeted food elimination diet.
Topics: Acetates; Anti-Allergic Agents; Arylsulfonates; Child; Cyclopropanes; Diarrhea; Diet; Enteritis; Eosinophilia; Food Hypersensitivity; Gastritis; Humans; Male; Quinolines; Sulfides; Sulfonium Compounds; Terfenadine; Treatment Outcome | 2020 |
Applying Biopharmaceutical Classification System criteria to predict the potential effect of Cremophor
Topics: Biological Availability; Biological Products; Humans; Polyethylene Glycols; Terfenadine | 2020 |
Efficacy of histamine H1 receptor antagonists azelastine and fexofenadine against cutaneous Leishmania major infection.
Topics: Animals; Histamine H1 Antagonists, Non-Sedating; Leishmania major; Leishmaniasis, Cutaneous; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Phthalazines; Terfenadine; Tissue Culture Techniques | 2020 |
Acute generalized exanthematous pustulosis induced by pseudoephedrine in a combination tablet with fexofenadine.
Topics: Acute Generalized Exanthematous Pustulosis; Humans; Pseudoephedrine; Tablets; Terfenadine | 2021 |
UPLC-MS/MS method for the simultaneous quantification of pravastatin, fexofenadine, rosuvastatin, and methotrexate in a hepatic uptake model and its application to the possible drug-drug interaction study of triptolide.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Diterpenes; Drug Interactions; Epoxy Compounds; Hepatocytes; Linear Models; Male; Methotrexate; Phenanthrenes; Pravastatin; Rats, Wistar; Reproducibility of Results; Rosuvastatin Calcium; Sensitivity and Specificity; Tandem Mass Spectrometry; Terfenadine | 2021 |
Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model.
Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Drug Interactions; Female; Fluoxetine; Histamine H1 Antagonists, Non-Sedating; Humans; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Pregnancy Complications; Stereoisomerism; Terfenadine | 2021 |
The Role of P-Glycoprotein in Decreasing Cell Membranes Permeability during Oxidative Stress.
Topics: ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Cell Membrane Permeability; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Lipid Peroxidation; NF-E2-Related Factor 2; Oxidative Stress; Terfenadine | 2021 |
Transcatheter aortic valve implantation for degenerated aortic valves: Experience with a new supra-annular device. The Spanish Allegra valve-in-valve (SAVIV) registry.
Topics: Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Catheters; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Prosthesis Design; Registries; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2021 |
Intestinal Absorption of Alogliptin Is Mediated by a Fruit-Juice-Sensitive Transporter.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Administration, Oral; Animals; Caco-2 Cells; Citrus paradisi; Citrus sinensis; Diabetes Mellitus, Type 2; Food-Drug Interactions; Fruit and Vegetable Juices; Half-Life; HEK293 Cells; Humans; Intestinal Absorption; Male; Malus; Organic Anion Transporters; Piperidines; Rats; Terfenadine; Uracil | 2021 |
The Allegra transcatheter heart valve: Short term results from a multicenter registry.
Topics: Aged; Aged, 80 and over; Animals; Aortic Valve; Aortic Valve Stenosis; Cattle; Female; Heart Valve Prosthesis; Humans; Male; Prosthesis Design; Registries; Risk Factors; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2021 |
Transfermoral transcatheter aortic valve implantation using self-expanding Allegra bioprosthesis: One-year single-center outcomes.
Topics: Aged; Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Female; Heart Valve Prosthesis; Humans; Prosthesis Design; Stroke; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2021 |
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine | 2021 |
Cytosolic Phospholipase A2 Is Required for Fexofenadine's Therapeutic Effects against Inflammatory Bowel Disease in Mice.
Topics: Animals; Biomarkers, Pharmacological; Disease Models, Animal; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipases A2, Cytosolic; Terfenadine | 2021 |
Novel self-expanding ALLEGRA transcatheter aortic valve for native aortic stenosis and degenerated bioprosthesis.
Topics: Aged; Aged, 80 and over; Animals; Aortic Valve; Aortic Valve Stenosis; Bioprosthesis; Cattle; Heart Valve Prosthesis; Humans; Prosthesis Design; Terfenadine; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2022 |
Targeting spinal microglia with fexofenadine-loaded nanoparticles prolongs pain relief in a rat model of neuropathic pain.
Topics: Animals; Microglia; Nanoparticles; Neuralgia; Rats; Spinal Cord; Spinal Nerves; Terfenadine | 2022 |
Cubosomes for Enhancing Intestinal Absorption of Fexofenadine Hydrochloride: In situ and in vivo Investigation.
Topics: Animals; Drug Liberation; Intestinal Absorption; Particle Size; Poloxamer; Rabbits; Rats; Terfenadine | 2022 |
Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach.
Topics: Adult; Bayes Theorem; Citrus paradisi; Humans; Organic Anion Transporters; Pharmaceutical Preparations; Terfenadine | 2023 |
Fexofenadine protects against lipopolysaccharide-induced acute lung injury by targeting cytosolic phospholipase A2.
Topics: Acute Lung Injury; Animals; Cytokines; Lipopolysaccharides; Lung; Mice; Mice, Knockout; NF-kappa B; Phospholipases A2; Signal Transduction; Terfenadine | 2023 |
The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine.
Topics: Animals; Caco-2 Cells; Food; Food-Drug Interactions; Humans; Intestinal Absorption; Mice; Organic Anion Transporters; Terfenadine | 2023 |