fexofenadine and rifampin

fexofenadine has been researched along with rifampin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bruce, MA; Haehner-Daniels, BD; Hall, SD; Hamman, MA1
Asghar, A; Gorski, JC; Haehner-Daniels, B; Hall, SD1
Addison, T; Jiang, X; Maleki, S; Naidong, W; Shou, WZ1
Burggraaff, JE; de Waart, DR; Elferink, RP; Kenworthy, KE; Schinkel, AH; van de Steeg, E; van der Kruijssen, CM; Wagenaar, E1
Akamine, Y; Fukizawa, S; Ikejiri, K; Kanamitsu, K; Kusuhara, H; Miura, M; Sugiyama, Y; Uno, T; Yasui-Furukori, N; Yokochi, M; Yoshida, K1
Akamine, Y; Ieiri, I; Miura, M; Uno, T; Yasui-Furukori, N1
Nezasa, K; Ogawa, K; Shimizu, R; Takai, N; Tanaka, Y; Watanabe, A; Watari, R; Yamaguchi, Y1

Reviews

2 review(s) available for fexofenadine and rifampin

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for fexofenadine and rifampin

ArticleYear
The effect of rifampin administration on the disposition of fexofenadine.
    Clinical pharmacology and therapeutics, 2001, Volume: 69, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aging; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Drug Interactions; Enzyme Inhibitors; Female; Half-Life; Histamine H1 Antagonists; Humans; Male; Metabolic Clearance Rate; Rifampin; Sex Characteristics; Terfenadine

2001
Effect of coadministration of single and multiple doses of rifampicin on the pharmacokinetics of fexofenadine enantiomers in healthy subjects.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Adult; Aged; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Reference Values; Rifampin; Terfenadine; Young Adult

2013
Effects of multiple-dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers.
    Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:1

    Topics: Anti-Allergic Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP2B6 Inducers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Japan; Rifampin; Terfenadine

2015

Other Studies

10 other study(ies) available for fexofenadine and rifampin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Humans; Lymphocytes; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Terfenadine

2002
Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.
    Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:20

    Topics: Adrenergic beta-Antagonists; Bronchodilator Agents; Chromatography, Liquid; Ephedrine; Histamine H1 Antagonists; Humans; Leprostatic Agents; Metoprolol; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Rifampin; Robotics; Solvents; Spectrometry, Mass, Electrospray Ionization; Terfenadine

2002
Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:8

    Topics: Animals; Bile Acids and Salts; Bilirubin; Female; Liver; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rifampin; Terfenadine

2010
Using improved serial blood sampling method of mice to study pharmacokinetics and drug-drug interaction.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:3

    Topics: Administration, Intravenous; Administration, Oral; Animals; Antipyrine; Biological Availability; Blood Specimen Collection; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Monitoring; Ibuprofen; Male; Mice, Inbred C57BL; Models, Animal; Organic Anion Transporters; Pravastatin; Reproducibility of Results; Rifampin; Tail; Terfenadine; Triazoles; Veins

2015