fexofenadine and histamine

fexofenadine has been researched along with histamine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.63)	18.2507
2000's	24 (63.16)	29.6817
2010's	13 (34.21)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM	1
Danielson, L; DeVos, C; Grant, JA; Rihoux, JP	1
Abdelaziz, MM; Devalia, JL; Khair, OA	1
Irman-Florjanc, T	1
Gu, X; Johnston, L; Simons, FE; Simons, KJ	1
Duvernelle, C; Frossard, N; Melac, M; Pauli, G; Purohit, A	1
DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM	1
Inoue, T; Katoh, N; Kishimoto, S; Matsunaga, K	1
Itoh, M; Iwabuchi, K; Mochizuki, H; Sakurada, Y; Tashiro, M; Watanabe, T; Yanai, K	1
Grzelewska-Rzymowska, I; Kroczyńska-Bednarek, J; Pietrzkowicz, M	1
Hagan, LL; More, DR; Napoli, DC	1
Boyce, M; Carey, W; Luria, X; Warrington, S	1
Jackson, CM; Lee, DK; Lipworth, BJ	1
Iizuka, H; Ishida-Yamamoto, A; Takahashi, H	1
Deslandes, B; Frossard, N; N'Gom, AS; Pauli, G; Purohit, A	1
Berisa, A; Corcóstegui, R; Innerárity, A; Labeaga, L; Orjales, A	1
Burtin, B; Hohlfeld, JM; Krug, N; Larbig, M; Luettig, B; Martin, L; Stamm, H	1
Kamei, J; Takahashi, Y	1
Kruszewski, J; Kłos, K; Sułek, K	1
Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K	1
Hayashi, S; Itabashi, T; Kamei, J; Kawai, K; Takahashi, Y	1
Casale, TB; Jones, DH; Romero, FA	1
Ikezawa, Z; Inomata, N; Tatewaki, S	1
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A	1
Ewert, R; Gläser, S; Gustavus, B; Hanf, G; Koch, B; Kunkel, G; Noga, O; Schäper, C	1
Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H	1
Behrens, CJ; Caliskan, G; Fano, S; Heinemann, U	1
Fukuoka, M; Ikoma, A; Kabashima, K; Miyachi, Y; Tanizaki, H	1
Church, MK; Maurer, M	1
Church, MK; Maurer, M; Schoepke, N	1
Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H	1
Cieślińska, A; Jarmołowska, B; Karolina Kordulewska, N; Kostyra, E; Matysiewicz, M	1
Dreyer, HC; Ely, MR; Halliwill, JR; Hocker, AD; Luttrell, MJ; Mangum, JE; Romero, SA; Sieck, DC; Struck, AJ; Turnbull, DW	1
Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E	1
Cieślińska, A; Fiedorowicz, E; Kordulewska, NK; Kostyra, E; Matysiewicz, M; Sienkiewicz-Szłapka, E	1
Akatsu, C; Fukui, H; Hishinuma, S; Kosaka, K; Shoji, M; Uesawa, Y	1
Chess-Williams, R; Moro, C; Stromberga, Z	1
Chwała, B; Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E; Moszyńska, M	1

Reviews

1 review(s) available for fexofenadine and histamine

Article	Year
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient? Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2012, Volume: 42, Issue:10 Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria	2012

Trials

18 trial(s) available for fexofenadine and histamine

Article	Year
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects. Allergy, 1999, Volume: 54, Issue:7 Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria	1999
Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2001, Volume: 86, Issue:1 Topics: Acetates; Adult; Allergens; Cyclopropanes; Depression, Chemical; Dermatitis, Allergic Contact; Drug Therapy, Combination; Female; Histamine; Humans; Injections; Leukotriene D4; Male; Middle Aged; Quinolines; Sulfides; Terfenadine; Time Factors	2001
Twenty-four hours of activity of cetirizine and fexofenadine in the skin. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2001, Volume: 86, Issue:4 Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Double-Blind Method; Drug Evaluation; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis; Skin; Skin Tests; Terfenadine; Time Factors	2001
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:2 Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria	2002
Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain. Life sciences, 2002, Dec-20, Volume: 72, Issue:4-5 Topics: Adult; Arousal; Brain; Brain Chemistry; Cetirizine; Cognition; Cross-Over Studies; Discrimination, Psychological; Double-Blind Method; Doxepin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Receptors, Histamine H1; Sleep Stages; Terfenadine; Tomography, Emission-Computed	2002
Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing. Allergy, 2003, Volume: 58, Issue:6 Topics: Cross-Over Studies; Double-Blind Method; Gastrointestinal Diseases; Histamine; Histamine H1 Antagonists; Humans; Plant Preparations; Skin; Skin Tests; Terfenadine; Time Factors	2003
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state. Drugs under experimental and clinical research, 2002, Volume: 28, Issue:6 Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine	2002
The effects of butterbur on the histamine and allergen cutaneous response. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 92, Issue:2 Topics: Acetates; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Humans; Male; Petasites; Phytotherapy; Quinolines; Skin Tests; Sulfides; Terfenadine	2004
Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance. Clinical and experimental dermatology, 2004, Volume: 29, Issue:5 Topics: Adult; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Dibenzoxepins; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Olopatadine Hydrochloride; Piperidines; Psychomotor Performance; Pyridines; Sleep Stages; Terfenadine	2004
Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:6 Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Skin Tests; Terfenadine; Urticaria	2004
Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine. British journal of clinical pharmacology, 2006, Volume: 62, Issue:2 Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Double-Blind Method; Face; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Nasal Provocation Tests; Nose; Piperazines; Skin Temperature; Terfenadine; Thermography	2006
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:125 Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria	2006
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:125 Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria	2006
Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2008, Volume: 100, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Child; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity, Immediate; Injections, Intramuscular; Male; Middle Aged; Skin Tests; Terfenadine; Time Factors; Treatment Outcome	2008
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:6 Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria	2009
The inhibition by levocetirizine and fexofenadine of the histamine-induced wheal and flare response in healthy Caucasian and Japanese volunteers. Acta dermato-venereologica, 2013, Volume: 93, Issue:3 Topics: Adult; Asian People; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Germany; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Male; Pruritus; Skin; Terfenadine; Time Factors; Treatment Outcome; Urticaria; White People; Young Adult	2013
Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations. The Journal of dermatological treatment, 2013, Volume: 24, Issue:6 Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Iontophoresis; Male; Pilot Projects; Pruritus; Terfenadine; Urticaria	2013
Evidence of a broad histamine footprint on the human exercise transcriptome. The Journal of physiology, 2016, 09-01, Volume: 594, Issue:17 Topics: Adult; Exercise; Female; Hemodynamics; Histamine; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Knee; Male; Muscle, Skeletal; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Terfenadine; Transcriptome; Young Adult	2016

Other Studies

19 other study(ies) available for fexofenadine and histamine

Article	Year
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4	2005
The potential of active metabolites of antihistamines in the management of allergic disease. Allergy, 2000, Volume: 55, Issue:5 Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases	2000
Kinetics of injected histamine in cat plasma after antihistamine prophylaxis. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49 Suppl 1 Topics: Animals; Cats; Cimetidine; Ethylenediamines; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Kinetics; Male; Terfenadine	2000
Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80. Journal of dermatological science, 2002, Volume: 30, Issue:3 Topics: Administration, Oral; Adult; Anti-Allergic Agents; Female; Glucocorticoids; Histamine; Humans; Hypersensitivity, Immediate; Male; p-Methoxy-N-methylphenethylamine; Prednisolone; Skin Tests; Terfenadine	2002
[Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 14, Issue:79 Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Receptors, Histamine H1; Terfenadine; Time Factors	2003
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist. Drugs in R&D, 2006, Volume: 7, Issue:4 Topics: Animals; Benzimidazoles; Bradykinin; Bronchial Spasm; Capillary Permeability; Cetirizine; Dermatitis; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Hypersensitivity; Male; Mice; Molecular Structure; Oxazolone; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H1; Serotonin; Structure-Activity Relationship; Terfenadine; Time Factors	2006
Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs. European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3 Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Citric Acid; Cough; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Histamine H1 Antagonists, Non-Sedating; Male; Purinergic P2 Receptor Antagonists; Receptors, Histamine H1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reflex; Terfenadine	2006
Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17. Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:2 Topics: Administration, Inhalation; Animals; Antigens, Fungal; Antitussive Agents; Aspergillus; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Citric Acid; Cough; Dose-Response Relationship, Drug; Fungal Proteins; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Male; Methacholine Chloride; Respiratory Hypersensitivity; Terfenadine	2008
Multiple H1-antihistamine-induced urticaria. The Journal of dermatology, 2009, Volume: 36, Issue:4 Topics: Administration, Oral; Adult; Drug Eruptions; Female; Histamine; Histamine H1 Antagonists; Humans; Immunologic Tests; Leukotriene B4; Loratadine; Piperidines; Pyridines; Skin Tests; Terfenadine; Urticaria	2009
Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis. Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:6 Topics: Adult; Aged; Anti-Inflammatory Agents; Antigens, Plant; Artemisia; Betula; Disease Progression; Eosinophil Cationic Protein; Female; Histamine; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Leukotriene D4; Male; Middle Aged; Nasal Lavage Fluid; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome	2009
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro. International archives of allergy and immunology, 2011, Volume: 155, Issue:1 Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extracellular Signal-Regulated MAP Kinases; GATA1 Transcription Factor; Gene Expression; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Macrophages; Male; Middle Aged; NF-kappa B; Phosphorylation; Phthalazines; Piperazines; Plant Proteins; Rhinitis, Allergic, Seasonal; Signal Transduction; Terfenadine; Tuberculin; Young Adult	2011
Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus. Neuroreport, 2011, Aug-03, Volume: 22, Issue:11 Topics: Acetylcholine; Animals; Attention; Cholinesterase Inhibitors; Cimetidine; Dimaprit; Electroencephalography; Hippocampus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Hypoxia, Brain; In Vitro Techniques; Male; Microelectrodes; Physostigmine; Pyramidal Tracts; Rats; Rats, Wistar; Terfenadine	2011
Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch. International archives of allergy and immunology, 2012, Volume: 158, Issue:2 Topics: Adult; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperidines; Pruritus; Pyridines; Skin; Terfenadine; Urticaria	2012
Impact of fexofenadine, osthole and histamine on peripheral blood mononuclear cell proliferation and cytokine secretion. European journal of pharmacology, 2015, Aug-15, Volume: 761 Topics: Adult; Cell Proliferation; Cells, Cultured; Coumarins; Cytokines; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Interleukin-10; Interleukin-6; Leukocytes, Mononuclear; Male; Terfenadine; Time Factors; Tumor Necrosis Factor-alpha	2015
Cytokine production by PBMC and serum from allergic and non-allergic subjects following in vitro histamine stimulation to test fexofenadine and osthole anti-allergic properties. European journal of pharmacology, 2016, Nov-15, Volume: 791 Topics: Adult; Anti-Allergic Agents; Coumarins; Cytokines; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Leukocytes, Mononuclear; Male; Terfenadine	2016
Changes in gene expression induced by histamine, fexofenadine and osthole: Expression of histamine H Immunobiology, 2017, Volume: 222, Issue:3 Topics: Adult; Case-Control Studies; Chemokine CCL5; Coumarins; Cyclooxygenase 2; Female; Gene Expression Regulation; Histamine; Humans; Hypersensitivity; Interleukin-1beta; Leukocytes, Mononuclear; Male; NF-kappa B; Receptors, Histamine H1; RNA, Messenger; Terfenadine	2017
Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H Biochemical pharmacology, 2017, Mar-15, Volume: 128 Topics: Animals; Aspartic Acid; Cations, Monovalent; Chlorpheniramine; CHO Cells; Cricetulus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Ligands; Mutation; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Histamine H1; Sodium Chloride; Terfenadine	2017
Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors. Scientific reports, 2019, 03-07, Volume: 9, Issue:1 Topics: Animals; Cyproheptadine; Histamine; Histamine Agonists; Histamine Antagonists; Mucous Membrane; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Swine; Terfenadine; Urinary Bladder; Urothelium	2019
A novel concept of immunological and allergy interactions in autism spectrum disorders: Molecular, anti-inflammatory effect of osthole. International immunopharmacology, 2019, Volume: 72 Topics: Anti-Inflammatory Agents; Autism Spectrum Disorder; Child; Child, Preschool; Coumarins; Cyclooxygenase 2; Female; Histamine; Histamine Antagonists; Humans; Hypersensitivity; Infant; Leukocytes, Mononuclear; Male; Terfenadine	2019