fentanyl isothiocyanate has been researched along with fentanyl in 19 studies
*Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078) [MeSH]
*Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burke, TR; Jacobson, AE; Klee, WA; Rice, KC; Silverton, JV; Simonds, WF; Streaty, RA | 1 |
| Chuang, DM; Coscia, CJ; McLean, S; Rice, KC; Roth, BL; Rothman, RB; Spain, JW | 1 |
| De Vries, TJ; Delay-Goyet, P; Mulder, AH; Roques, BP; Schoffelmeer, AN | 1 |
| Bowen, WD; Jacobson, AE; Rice, KC; Rodrigues, PA; Wanzor, TE | 1 |
| Heijna, MH; Hogenboom, F; Mulder, AH; Rice, KC; Schoffelmeer, AN | 1 |
| Heijna, MH; Hogenboom, F; Jacobson, AE; Mulder, AH; Rice, KC; Schoffelmeer, AN; Van Gelderen, JG | 1 |
| Burke, TR; Danks, JA; Herkenham, M; Jacobson, AE; Rice, KC; Rothman, RB | 1 |
| Aceto, MD; Bajwa, BS; Harris, LS; Jacobson, AE; Klee, WA; Lessor, RA; May, EL; Rice, KC; Smith, CB; Streaty, RA | 1 |
| Quinn, DM | 1 |
| Bowen, WD; Burke, TR; Bykov, V; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB; Schumacher, UK | 1 |
| Burke, TR; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB | 1 |
| Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB | 2 |
| Bajwa, BS; Burke, TR; Jacobson, AE; Klee, WA; Rice, KC; Streaty, RA | 1 |
| Jacobson, AE; Klee, WA; Lessor, RA; Rice, KC; Streaty, RA | 1 |
| Burke, TR; Jacobson, AE; Klee, WA; Rice, KC; Simonds, WF; Sweat, FW | 1 |
| De Vries, TJ; Hogenboom, F; Mulder, AH; Schoffelmeer, AN | 1 |
| Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK | 1 |
| Auchampach, JA; Gross, ER; Gross, GJ; Hsu, AK; Peart, JN | 1 |
19 other study(ies) available for fentanyl isothiocyanate and fentanyl
| Article | Year |
|---|---|
Probes for narcotic receptor mediated phenomena. 12. cis-(+)-3-Methylfentanyl isothiocyanate, a potent site-directed acylating agent for delta opioid receptors. Synthesis, absolute configuration, and receptor enantioselectivity.
Topics: Acylation; Adenylyl Cyclase Inhibitors; Analgesics; Animals; Brain; Enkephalin, Methionine; Fentanyl; In Vitro Techniques; Isothiocyanates; Ligands; Mice; Molecular Conformation; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Tritium; X-Ray Diffraction | 1986 |
Cross-linking of [125I]beta-endorphin to mu-opioid receptors during development.
Topics: Alkylation; Animals; Autoradiography; beta-Endorphin; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Female; Fentanyl; Isothiocyanates; Male; Microsomes; Rats; Receptors, Opioid; Receptors, Opioid, mu; Succinimides; Synaptic Membranes; Thiocyanates | 1989 |
Selective effects of [D-Ser2(O-t-butyl),Leu5]enkephalyl-Thr6 and [D-Ser2(O-t-butyl),Leu5]enkephalyl-Thr6 (O-t-butyl), two new enkephalin analogues, on neurotransmitter release and adenylate cyclase in rat brain slices.
Topics: Adenylyl Cyclases; Alkylating Agents; Animals; Brain; Corpus Striatum; Cyclic AMP; Dopamine; Electric Stimulation; Enkephalins; Fentanyl; Isothiocyanates; Male; Neurotransmitter Agents; Oligopeptides; Rats; Rats, Inbred Strains | 1989 |
Differential coupling of mu-competitive and mu-noncompetitive delta opiate receptors to guanine nucleotide binding proteins in rat brain membranes.
Topics: Adenylate Cyclase Toxin; Alkylating Agents; Animals; Binding, Competitive; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; GTP-Binding Proteins; Intracellular Membranes; Isothiocyanates; Kinetics; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptosomes; Virulence Factors, Bordetella | 1988 |
Fentanyl isothiocyanate reveals the existence of physically associated mu- and delta-opioid receptors mediating inhibition of adenylate cyclase in rat neostriatum.
Topics: Adenylyl Cyclase Inhibitors; Animals; Caudate Nucleus; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; In Vitro Techniques; Isothiocyanates; Male; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1988 |
Mu-, delta- and kappa-opioid receptor-mediated inhibition of neurotransmitter release and adenylate cyclase activity in rat brain slices: studies with fentanyl isothiocyanate.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Brain; Dopamine; Fentanyl; In Vitro Techniques; Isothiocyanates; Male; Naloxone; Neurotransmitter Agents; Norepinephrine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1988 |
Evidence that the delta-selective alkylating agent, fit, alters the mu-noncompetitive opiate delta binding site.
Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Isothiocyanates; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Probes for narcotic receptor mediated phenomena. 13. Potential irreversible narcotic antagonist-based ligands derived from 6,14-endo-ethenotetrahydronororipavine with 7-(methoxyfumaroyl)amino, (bromoacetyl)amino, or isothiocyanate electrophiles: chemistry
Topics: Animals; Brain; Enkephalin, Leucine; Fentanyl; In Vitro Techniques; Isothiocyanates; Ligands; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Thebaine; Thiocyanates | 1986 |
The effectiveness, in vitro, of miconazole and ketoconazole combined with tissue conditioners in inhibiting the growth of Candida albicans.
Topics: Acrylic Resins; Amphotericin B; Candida albicans; Fentanyl; Isothiocyanates; Ketoconazole; Methylmethacrylates; Miconazole; Nystatin; Phthalic Acids; Tissue Conditioning, Dental | 1985 |
Preparation of rat brain membranes greatly enriched with either type-I-delta or type-II-delta opiate binding sites using site directed alkylating agents: evidence for a two-site allosteric model.
Topics: Alkylating Agents; Allosteric Regulation; Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Male; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates | 1984 |
Morphine noncompetitively inhibits [3H]leucine enkephalin binding to membranes lacking type-II delta binding sites: evidence for a two-site allosteric model.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Leucine; Fentanyl; Isothiocyanates; Kinetics; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1984 |
Ionic conditions differentially affect 3H-DADL binding to type-I and type-II opiate delta receptors in vitro.
Topics: Animals; Brain; Calcium; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Manganese; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Sodium; Thiocyanates | 1984 |
Irreversible ligands with high selectivity toward delta and mu opiate receptors.
Topics: Alkylation; Animals; Benzimidazoles; Brain; Cells, Cultured; Chemical Phenomena; Chemistry; Enkephalin, Methionine; Fentanyl; Isothiocyanates; Ligands; Rats; Receptors, Opioid; Thebaine | 1983 |
Probes for narcotic receptor mediated phenomena. 10. Irreversible ligands to opioid receptors based on biologically potent endoethenooripavines. Reversible binding of fit to mu and delta opioid receptors.
Topics: Alkylating Agents; Animals; Benzimidazoles; Binding, Competitive; Brain; Fentanyl; In Vitro Techniques; Isothiocyanates; Membranes; Morphine Derivatives; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thebaine | 1984 |
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding.
Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed | 1984 |
Identification of a Mr 58 000 glycoprotein subunit of the opiate receptor.
Topics: Animals; Fentanyl; Glycoproteins; Hybrid Cells; Indicators and Reagents; Isothiocyanates; Macromolecular Substances; Molecular Weight; Receptors, Opioid | 1982 |
Mu- and delta-opioid receptors inhibitorily linked to dopamine-sensitive adenylate cyclase in rat striatum display a selectivity profile toward endogenous opioid peptides different from that of presynaptic mu, delta and kappa receptors.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Fentanyl; In Vitro Techniques; Isothiocyanates; Male; Naloxone; Norepinephrine; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Opioid, delta; Receptors, Opioid, mu; Receptors, Presynaptic; Sulpiride | 1993 |
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation | 1997 |
Extending the cardioprotective window using a novel delta-opioid agonist fentanyl isothiocyanate via the PI3-kinase pathway.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Disease Models, Animal; Fentanyl; Heart Rate; Hemodynamics; Ischemic Preconditioning; Isothiocyanates; Male; Myocardial Infarction; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 2005 |