fentanyl has been researched along with norfentanyl in 66 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (9.09) | 18.2507 |
2000's | 14 (21.21) | 29.6817 |
2010's | 32 (48.48) | 24.3611 |
2020's | 14 (21.21) | 2.80 |
Authors | Studies |
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Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B | 1 |
McMullin, M; Rieders, MF; Schulman, S; Silverstein, JH; Zahl, K | 1 |
Feierman, DE | 2 |
Guengerich, FP; Tateishi, T; Wood, AJ; Wood, M | 1 |
Guengerich, FP; Krivoruk, Y; Tateishi, T; Ueng, YF; Wood, AJ; Wood, M | 1 |
Feierman, DE; Lasker, JM | 1 |
Andurkar, SV; Clark, CR; DeRuiter, J; Huber, T; Valaer, AK | 1 |
Day, J; Lugo, RA; Slawson, M; Wilkins, D | 1 |
Altuntas, TG; Hoffer, C; Kharasch, ED; Whittington, D | 1 |
Carpenter, JW; Hunter, RP; Isaza, R; Koch, DE | 1 |
Hoffer, C; Kharasch, ED; Whittington, D | 2 |
Backer, R; Poklis, A | 1 |
Ekman, L; Huynh, NH; Johansson, M; Tyrefors, N | 1 |
Gock, SB; Jannetto, PJ; Jentzen, JM; Jin, M; Wong, SH | 1 |
Kuepper, U; Madea, B; Musshoff, F; Trafkowski, J | 1 |
Coopman, V; Cordonnier, J; Pien, K; Van Varenbergh, D | 1 |
Behonick, GS; Flomenbaum, MA; Hull, MJ; Juhascik, M; Mazur, F | 1 |
Laine, K; Neuvonen, M; Neuvonen, PJ; Olkkola, KT; Saari, TI | 1 |
Callery, PS; Kraner, JC; Peer, CJ; Shakleya, DM; Younis, IR | 1 |
Godderis, L; Menten, JJ; Poels, KL; Van Nimmen, NF; Veulemans, HA | 1 |
Carson, HJ; Dudley, MH; Garg, U; Knight, LD | 1 |
Tytgat, J; Verplaetse, R | 2 |
Alvarez, I; Bermejo, AM; Cabarcos, P; Fernández, P; Strano-Rossi, S; Tabernero, MJ | 1 |
Christians, U; Clavijo, CF; Cromie, M; Galinkin, JL; Hoffman, KL; Schniedewind, B; Thomas, JJ | 1 |
Haefeli, WE; Jantos, R; König, SK; Mahlke, N; Mikus, G; Skopp, G; Weiss, J; Ziesenitz, VC | 1 |
Endres, GW; Fantegrossi, WE; James, LP; Kennedy, PD; Knight, LD; Marraffa, JM; Moran, CL; Moran, JH; Patton, AL; Pulla, S; Rusch, NJ; Seely, KA | 1 |
Doi, M; Kawakami, J; Naito, T; Sato, S; Tanaka, N; Yagi, T | 1 |
Bista, SR; Hardy, J; Haywood, A; Lobb, M; Norris, R; Tapuni, A | 2 |
Mahlke, NS; Mikus, G; Skopp, G; Ziesenitz, V | 1 |
Haefeli, WE; König, SK; Mahlke, NS; Mikus, G; Skopp, G; Ziesenitz, VC | 1 |
Bista, SR; Good, P; Hardy, J; Haywood, A; Lobb, M; Norris, R; Tapuni, A | 1 |
Arbefeville, E; Chrostowski, L; Devers, K; Hair, L; Mainland, M; Merves, M; Pearson, J; Poklis, A; Poklis, J; Wolf, C | 1 |
Chiravuri, S; Kaye, AD; Ruan, X | 3 |
Backer, R; Cummings, OT; Enders, JR; McIntire, GL; Poklis, A | 1 |
ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B | 1 |
Cummings, OT; Enders, J; McIntire, GL | 1 |
Goggin, MM; Janis, GC; Nguyen, A | 1 |
Brooker, IT; Dolinak, D; Gilson, TP; Kaspar, CK; Lavins, ES; Mazzola, CD; Perch, S; Schueler, HE; Sofalvi, S | 1 |
Chatterton, CN; Scott-Ham, M | 1 |
Gill, CG; Hessels, AJ; Krogh, ET; Palaty, J; Vandergrift, GW | 1 |
Avedschmidt, S; Gupta, A; Isenschmid, D; Kesha, K; Moons, D; Schmidt, C | 1 |
Palmquist, KB; Swortwood, MJ | 2 |
Doberentz, E; Geile, J; Kraemer, M; Maas, A; Madea, B | 1 |
Anders, S; Andresen-Streichert, H; Falckenberg, M; Iwersen-Bergmann, S; Mueller, A; Otto, B; Reiter, A | 1 |
Apollonio, LG; Brooker, IT; Clyde, CL; Gilson, TP; Goggin, C; Kaspar, CK; Kucmanic, J; Lavins, ES; Marshall, B; Mazzola, CD; Mitchell-Mata, CL; Moore, D; Rico, RN; Sofalvi, S | 1 |
Bardenheuer, HJ; Burhenne, J; Geist, MJP; Mikus, G; Skopp, G; Ziesenitz, VC | 1 |
Amante, E; Bigiarini, R; Di Corcia, D; McKnight, C; Palamar, JJ; Salomone, A; Vincenti, M; Vinsick, L | 1 |
Gleba, J; Kim, J | 1 |
Arroyo-Mora, LE; Bailey, K; Cox, J; DelTondo, J; Field, A; Gebhardt, M; Kraner, J; Ott, C; Train, A | 1 |
Chen, H; Feng, S; Li, Z; Liu, K; Wang, P | 1 |
Hobelmann, JG; Huhn, AS; Oyler, GA; Strain, EC | 1 |
Bisch, M; Gambier, N; Gibaja, V; Javot, L; Jouzeau, JY; Jung, J; Kolodziej, A; Pape, E; Scala-Bertola, J | 1 |
Field, TA; Saia, K; Wanar, A | 1 |
Bian, J; Chen, Y; Duan, H; Li, L; Liu, L; Lyu, L; Xu, Z; Yu, X; Zhang, Y | 1 |
Carotti, A; Cirrincione, M; Mercolini, L; Protti, M; Sardella, R; Varfaj, I | 1 |
Al-Qurain, AA; Mackenzie, L; Roberts, MS; Wiese, MD; Williams, DB | 1 |
Basu, S; Bernstein, S; Flood, JG; Griggs, D; Khaliq, T; Leffert, L; Mahowald, G; Siegel, M; Uljon, S | 1 |
Brousa, E; Kevrekidis, DP; Mastrogianni, O; Orfanidis, A; Raikos, N; Zagelidou, H | 1 |
Clinton Frazee, C; Garg, U; Shell, S | 1 |
7 trial(s) available for fentanyl and norfentanyl
Article | Year |
---|---|
Quinidine as a probe for the role of p-glycoprotein in the intestinal absorption and clinical effects of fentanyl.
Topics: Administration, Oral; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Fentanyl; Humans; Injections, Intravenous; Intestinal Absorption; Male; Miosis; Quinidine; Time Factors | 2004 |
Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate.
Topics: Adult; Analgesics, Opioid; Antibiotics, Antitubercular; Antiemetics; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Beverages; Chromatography, High Pressure Liquid; Citrus; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Female; Fentanyl; Food-Drug Interactions; Half-Life; Humans; Intestines; Liver; Male; Oxidoreductases, N-Demethylating; Pupil; Rifampin; Spectrometry, Mass, Electrospray Ionization; Troleandomycin | 2004 |
Urine concentrations of fentanyl and norfentanyl during application of Duragesic transdermal patches.
Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Fentanyl; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Immunoenzyme Techniques; Pain | 2004 |
Effect of voriconazole and fluconazole on the pharmacokinetics of intravenous fentanyl.
Topics: Administration, Oral; Analgesics, Opioid; Antifungal Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Inhibitors; Female; Fentanyl; Fluconazole; Humans; Injections, Intravenous; Male; Pyrimidines; Tissue Distribution; Triazoles; Voriconazole | 2008 |
Fentanyl pharmacokinetics is not dependent on hepatic uptake by organic anion-transporting polypeptide 1B1 in human beings.
Topics: Adult; Analgesics, Opioid; Biological Transport; Cross-Over Studies; Female; Fentanyl; Genotype; HEK293 Cells; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Male; Metabolic Clearance Rate; Middle Aged; Organic Anion Transporters; Polymorphism, Single Nucleotide; Prospective Studies; Rifampin | 2013 |
Pharmacokinetic interaction of intravenous fentanyl with ketoconazole.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fentanyl; Healthy Volunteers; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Naloxone; Prospective Studies; Tandem Mass Spectrometry; Young Adult | 2015 |
Minor contribution of cytochrome P450 3A activity on fentanyl exposure in palliative care cancer patients.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Cytochrome P-450 CYP3A; Female; Fentanyl; Humans; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Neoplasms; Palliative Care; Transdermal Patch | 2019 |
59 other study(ies) available for fentanyl and norfentanyl
Article | Year |
---|---|
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation | 2019 |
An analysis of the duration of fentanyl and its metabolites in urine and saliva.
Topics: Adult; Female; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; Saliva; Substance Abuse Detection; Time Factors | 1993 |
Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes.
Topics: Anesthetics, Intravenous; Animals; Anti-Bacterial Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Erythromycin; Fentanyl; GABA Modulators; Gas Chromatography-Mass Spectrometry; Isoenzymes; Ketoconazole; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1996 |
Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol.
Topics: Analgesics, Opioid; Biotransformation; Dealkylation; Drug Monitoring; Fentanyl; Humans; In Vitro Techniques; Microsomes, Liver; Phenylacetates; Phenylethyl Alcohol; Tritium | 1995 |
Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation.
Topics: Analgesics, Opioid; Animals; Antibodies; Antibody Specificity; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Erythromycin; Fentanyl; Humans; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Norpregnenes; Rabbits; Sufentanil; Troleandomycin | 1996 |
Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
Topics: Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; Ketoconazole; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline; Tolbutamide | 1996 |
Development of a gas chromatographic-mass spectrometric drug screening method for the N-dealkylated metabolites of fentanyl, sufentanil, and alfentanil.
Topics: Alfentanil; Analgesics, Opioid; Drug Residues; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Sensitivity and Specificity; Sufentanil | 1997 |
The effect of paracetamol (acetaminophen) on fentanyl metabolism in vitro.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; Animals; Biotransformation; Fentanyl; Humans; In Vitro Techniques; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 2000 |
Analysis of fentanyl and norfentanyl in human plasma by liquid chromatography-tandem mass spectrometry using electrospray ionization.
Topics: Adolescent; Child; Child, Preschool; Chromatography, High Pressure Liquid; Fentanyl; Humans; Infant; Sensitivity and Specificity; Specimen Handling; Spectrometry, Mass, Electrospray Ionization | 2003 |
Simultaneous extraction and quantitation of fentanyl and norfentanyl from primate plasma with LC/MS detection.
Topics: Animals; Chromatography, Liquid; Fentanyl; Mass Spectrometry; Primates | 2004 |
Influence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate.
Topics: Administration, Oral; Aged; Aging; Analgesics, Opioid; Area Under Curve; Chromatography, High Pressure Liquid; Female; Fentanyl; Humans; Intestinal Absorption; Male; Middle Aged; Mucous Membrane; Pupil; Spectrometry, Mass, Electrospray Ionization | 2004 |
Determination of fentanyl in human plasma and fentanyl and norfentanyl in human urine using LC-MS/MS.
Topics: Chromatography, Liquid; Fentanyl; Humans; Mass Spectrometry | 2005 |
Pharmacogenomics as molecular autopsy for forensic toxicology: genotyping cytochrome P450 3A4*1B and 3A5*3 for 25 fentanyl cases.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Autopsy; Cause of Death; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Fingerprinting; Female; Fentanyl; Homozygote; Humans; Male; Middle Aged; Opioid-Related Disorders; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Substance Abuse Detection | 2005 |
An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites.
Topics: Analgesics, Opioid; Chromatography, Liquid; Fentanyl; Humans; Morphine Derivatives; Palliative Care; Patient Compliance; Spectrometry, Mass, Electrospray Ionization; Tilidine | 2006 |
LC-MS/MS analysis of fentanyl and norfentanyl in a fatality due to application of multiple Durogesic transdermal therapeutic systems.
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Bile; Chromatography, Liquid; Female; Fentanyl; Forensic Toxicology; Gastrointestinal Contents; Humans; Kidney; Liver; Neoplasms; Pain; Spectrometry, Mass, Electrospray Ionization; Suicide; Vitreous Body | 2007 |
Fatalities associated with fentanyl and co-administered cocaine or opiates.
Topics: Accidents; Adult; Aged; Aged, 80 and over; Cannabinoids; Cause of Death; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Drug Overdose; Ethanol; Female; Fentanyl; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Narcotics; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders | 2007 |
Direct-injection mass spectrometric method for the rapid identification of fentanyl and norfentanyl in postmortem urine of six drug-overdose cases.
Topics: Adult; Deuterium; Drug Overdose; Fatal Outcome; Female; Fentanyl; Forensic Medicine; Humans; Male; Middle Aged; Narcotics; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2007 |
Fentanyl transdermal absorption linked to pharmacokinetic characteristics in patients undergoing palliative care.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Dose-Response Relationship, Drug; Drug Carriers; Female; Fentanyl; Humans; Male; Middle Aged; Neoplasms; Pain; Palliative Care; Skin Absorption | 2010 |
A fatality involving an unusual route of fentanyl delivery: Chewing and aspirating the transdermal patch.
Topics: Administration, Oral; Adult; Bronchi; Fentanyl; Forensic Pathology; Forensic Toxicology; Humans; Male; Mastication; Methamphetamine; Narcotics; Respiratory Aspiration; Substance-Related Disorders | 2010 |
Development and validation of a sensitive ultra performance liquid chromatography tandem mass spectrometry method for the analysis of fentanyl and its major metabolite norfentanyl in urine and whole blood in forensic context.
Topics: Chromatography, High Pressure Liquid; Fentanyl; Forensic Sciences; Humans; Tandem Mass Spectrometry | 2010 |
Determination of fentanyl, metabolite and analogs in urine by GC/MS.
Topics: Alfentanil; Calibration; Fentanyl; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Linear Models; Liquid-Liquid Extraction; Reproducibility of Results; Sufentanil | 2011 |
Development and validation of a sensitive UPLC-MS/MS method for the analysis of narcotic analgesics in urine and whole blood in forensic context.
Topics: Analgesics, Opioid; Analysis of Variance; Buprenorphine; Chromatography, Liquid; Fentanyl; Forensic Toxicology; Humans; Meperidine; Pirinitramide; Regression Analysis; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tilidine; Tramadol | 2012 |
A low blood volume LC-MS/MS assay for the quantification of fentanyl and its major metabolites norfentanyl and despropionyl fentanyl in children.
Topics: Blood Volume; Child; Chromatography, High Pressure Liquid; Fentanyl; Humans; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
Quantitative measurement of acetyl fentanyl and acetyl norfentanyl in human urine by LC-MS/MS.
Topics: Analgesics, Opioid; Animals; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Fentanyl; Humans; Male; Rats; Tandem Mass Spectrometry; Urinalysis | 2014 |
Impact of CYP3A5*3 on plasma exposure and urinary excretion of fentanyl and norfentanyl in the early postsurgical period.
Topics: Aged; Analgesics, Opioid; Body Mass Index; Cytochrome P-450 CYP3A; Female; Fentanyl; Genotype; Humans; Infusions, Intravenous; Japan; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Genetic; Postoperative Period; Renal Elimination | 2014 |
Development, validation and application of an HPLC-MS/MS method for the determination of fentanyl and nor-fentanyl in human plasma and saliva.
Topics: Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Fentanyl; Humans; Linear Models; Pain; Reproducibility of Results; Saliva; Sensitivity and Specificity; Tandem Mass Spectrometry | 2014 |
Quantitative low-volume assay for simultaneous determination of fentanyl, norfentanyl, and minor metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Topics: Chromatography, Liquid; Fentanyl; Forensic Toxicology; Humans; Limit of Detection; Narcotics; Tandem Mass Spectrometry | 2014 |
Protein binding of fentanyl and its metabolite nor-fentanyl in human plasma, albumin and α-1 acid glycoprotein.
Topics: Administration, Cutaneous; Adsorption; Adult; Aged; Aged, 80 and over; Albumins; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Male; Metabolome; Middle Aged; Orosomucoid; Protein Binding; Solutions; Ultrafiltration | 2015 |
Saliva versus Plasma for Pharmacokinetic and Pharmacodynamic Studies of Fentanyl in Patients with Cancer.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chromatography, High Pressure Liquid; Female; Fentanyl; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Saliva; Tandem Mass Spectrometry | 2015 |
Postmortem tissue distribution of acetyl fentanyl, fentanyl and their respective nor-metabolites analyzed by ultrahigh performance liquid chromatography with tandem mass spectrometry.
Topics: Adult; Bile; Brain Chemistry; Chromatography, Liquid; Designer Drugs; Fentanyl; Forensic Toxicology; Humans; Liver; Middle Aged; Narcotics; Postmortem Changes; Tandem Mass Spectrometry; Tissue Distribution; Vitreous Body | 2015 |
Using postmortem blood and urine norfentanyl/fentanyl ratios in the investigation of fentanyl-related deaths.
Topics: Analgesics, Opioid; Drug Overdose; Fentanyl; Forensic Toxicology; Humans | 2016 |
Toxicological testing when evaluating fatal cases suspected of acute fentanyl toxicity.
Topics: Analgesics, Opioid; Cytochrome P-450 Enzyme System; Drug Tolerance; Fentanyl; Forensic Toxicology; Humans; Transdermal Patch | 2016 |
Fentanyl-Norfentanyl Concentrations During Transdermal Patch Application: LC-MS-MS Urine Analysis.
Topics: Administration, Cutaneous; Adult; Aged; Chromatography, Liquid; Female; Fentanyl; Humans; Male; Middle Aged; Models, Theoretical; Retrospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Transdermal Patch | 2016 |
LC-MS-MS Method for the Analysis of Miscellaneous Drugs in Wastewater During Football Games III.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Residues; Fentanyl; Football; Humans; Illicit Drugs; Limit of Detection; Meperidine; Methadone; Mississippi; Phencyclidine; Pyrrolidines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater | 2016 |
Response to: Fentanyl-Norfentanyl Concentrations During Transdermal Patch Application: LC-MS-MS Urine Analysis.
Topics: Chromatography, Liquid; Fentanyl; Tandem Mass Spectrometry; Transdermal Patch | 2017 |
Fentanyl-Norfentanyl Concentrations During Transdermal Patch Application: LC-MS-MS Urine Analysis.
Topics: Chromatography, Liquid; Fentanyl; Tandem Mass Spectrometry; Transdermal Patch | 2017 |
Identification of Unique Metabolites of the Designer Opioid Furanyl Fentanyl.
Topics: Analgesics, Opioid; Fentanyl; Furans; Illicit Drugs; Mass Spectrometry; Substance Abuse Detection | 2017 |
An LC-MS-MS Method for the Analysis of Carfentanil, 3-Methylfentanyl, 2-Furanyl Fentanyl, Acetyl Fentanyl, Fentanyl and Norfentanyl in Postmortem and Impaired-Driving Cases.
Topics: Analgesics, Opioid; Autopsy; Chromatography, Liquid; Driving Under the Influence; Enzyme-Linked Immunosorbent Assay; Fentanyl; Furans; Gas Chromatography-Mass Spectrometry; Humans; Substance Abuse Detection; Tandem Mass Spectrometry | 2017 |
The distribution and redistribution of fentanyl & norfentanyl in post mortem samples.
Topics: Accidents; Analgesics, Opioid; Chromatography, Liquid; Drug Overdose; Fentanyl; Forensic Toxicology; Humans; Liver; Opioid-Related Disorders; Postmortem Changes; Tandem Mass Spectrometry; Vitreous Body | 2018 |
Paper spray mass spectrometry for the direct, semi-quantitative measurement of fentanyl and norfentanyl in complex matrices.
Topics: Fentanyl; Mass Spectrometry | 2018 |
Acetyl Fentanyl: Trends and Concentrations in Metro Detroit.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Central Nervous System Depressants; Chromatography, Liquid; Cocaine; Cohort Studies; Coroners and Medical Examiners; Drug Overdose; Ethanol; Female; Fentanyl; Heroin; Humans; Illicit Drugs; Male; Mass Spectrometry; Michigan; Opioid-Related Disorders; Racial Groups; Urban Population | 2019 |
Data-independent screening method for 14 fentanyl analogs in whole blood and oral fluid using LC-QTOF-MS.
Topics: Alfentanil; Chromatography, Liquid; Fentanyl; Forensic Toxicology; Furans; Humans; Illicit Drugs; Limit of Detection; Mass Spectrometry; Remifentanil; Saliva; Solid Phase Extraction; Substance Abuse Detection; Substance-Related Disorders; Sufentanil | 2019 |
Fatal misuse of transdermal fentanyl patches.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Chromatography, Liquid; Female; Fentanyl; Hair; Humans; Male; Mass Spectrometry; Opioid-Related Disorders; Prescription Drug Misuse; Pulmonary Edema; Retrospective Studies; Transdermal Patch; Urinary Retention | 2019 |
Fast increase of postmortem fentanyl blood concentrations after transdermal application: A call to careful interpretation.
Topics: Aged; Analgesics, Opioid; Chromatography, Liquid; Edetic Acid; Female; Fentanyl; Forensic Toxicology; Humans; Male; Middle Aged; Postmortem Changes; Tandem Mass Spectrometry; Transdermal Patch | 2019 |
Unique Structural/Stereo-Isomer and Isobar Analysis of Novel Fentanyl Analogues in Postmortem and DUID Whole Blood by UHPLC-MS-MS.
Topics: Analgesics, Opioid; Autopsy; Chromatography, High Pressure Liquid; Fentanyl; Humans; Isomerism; Limit of Detection; Tandem Mass Spectrometry | 2019 |
Toward the Interpretation of Positive Testing for Fentanyl and Its Analogs in Real Hair Samples: Preliminary Considerations.
Topics: Analgesics, Opioid; Chromatography, Liquid; Fentanyl; Hair; Humans; Illicit Drugs; Limit of Detection; Substance Abuse Detection | 2020 |
Determination of Morphine, Fentanyl and Their Metabolites in Small Sample Volumes Using Liquid Chromatography Tandem Mass Spectrometry.
Topics: Animals; Chromatography, Liquid; Fentanyl; Heroin; Morphine; Morphine Derivatives; Rats; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry | 2020 |
Quantitation of Fentanyl and Metabolites from Liver Tissue Using a Validated QuEChERS Extraction and LC-MS-MS Analysis.
Topics: Analgesics, Opioid; Autopsy; Chromatography, Liquid; Drug Overdose; Fentanyl; Forensic Toxicology; Humans; Limit of Detection; Liver; Postmortem Changes; Substance Abuse Detection; Tandem Mass Spectrometry | 2021 |
Development and Clinical Validation of a Sensitive Lateral Flow Assay for Rapid Urine Fentanyl Screening in the Emergency Department.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biological Assay; Chromatography, Liquid; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Gold; Humans; Immunoassay; Male; Metal Nanoparticles; Middle Aged; Point-of-Care Testing; Sensitivity and Specificity; Substance Abuse Detection; Tandem Mass Spectrometry; Urinalysis | 2020 |
Quantification of Furanylfentanyl and its Metabolites in Human and Rat Plasma Using LC-MS-MS.
Topics: Analgesics, Opioid; Animals; Chromatography, Liquid; Fentanyl; Forensic Toxicology; Furans; Humans; Illicit Drugs; Limit of Detection; Plasma; Rats; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry | 2020 |
Protracted renal clearance of fentanyl in persons with opioid use disorder.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Chromatography, Liquid; Drug Contamination; Female; Fentanyl; Humans; Male; Mass Spectrometry; Middle Aged; Narcotics; Opioid-Related Disorders | 2020 |
Multiplex detection of 14 fentanyl analogues and U-47700 in biological samples: Application to a panel of French hospitalized patients.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Opioid; Benzamides; Child; Child, Preschool; Chromatography, Liquid; Female; Fentanyl; France; Furans; Humans; Infant; Infant, Newborn; Limit of Detection; Male; Middle Aged; Neonatal Abstinence Syndrome; Piperidines; Remifentanil; Retrospective Studies; Substance Abuse Detection; Substance-Related Disorders; Sufentanil; Tandem Mass Spectrometry; Young Adult | 2020 |
Delayed Norfentanyl Clearance During Pregnancy.
Topics: Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Metabolic Clearance Rate; Opioid-Related Disorders; Pregnancy; Pregnancy Complications | 2020 |
Determination of Fentanyl, Alpha-Methylfentanyl, Beta-Hydroxyfentanyl and the Metabolite Norfentanyl in Rat Urine by LC-MS-MS.
Topics: Analgesics, Opioid; Animals; Chromatography, Liquid; Fentanyl; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2022 |
Original enantioseparation of illicit fentanyls with cellulose-based chiral stationary phases under polar-ionic conditions.
Topics: Cellulose; Chromatography, High Pressure Liquid; Fentanyl; Mass Spectrometry; Stereoisomerism | 2021 |
Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetr
Topics: Aged; Chromatography, Liquid; Fentanyl; Humans; Morphinans; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry; Tramadol | 2021 |
Bupivacaine Metabolite Can Interfere with Norfentanyl Measurement by LC-MS/MS.
Topics: Bupivacaine; Chromatography, Liquid; Female; Fentanyl; Humans; Tandem Mass Spectrometry | 2022 |
Determination of fentanyl and norfentanyl in cerumen in the setting of postmortem investigation.
Topics: Analgesics, Opioid; Cerumen; Fentanyl; Forensic Toxicology; Tandem Mass Spectrometry | 2022 |
Quantification of Fentanyl and Norfentanyl in Whole Blood Using Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Analgesics, Opioid; Chromatography, Liquid; Fentanyl; Tandem Mass Spectrometry | 2024 |