fentanyl and noralfentanil

fentanyl has been researched along with noralfentanil in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's5 (71.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guengerich, FP; Wood, AJ; Wood, M; Yun, CH1
Cork, RC; Gandolfi, AJ; Perry, DF; Weldon, ST1
Hendrickx, JJ; Heykants, JJ; Lauwers, W; Lavrijsen, KL; Meuldermans, WE; Van Dyck, DM; Van Houdt, JM; Woestenborghs, RJ1
Kharasch, ED; Kunze, KL; Labroo, RB; Podoll, T; Thummel, KE; Trager, WF1
Kharasch, ED; Labroo, R; Mautz, DS1
Guengerich, FP; Krivoruk, Y; Tateishi, T; Ueng, YF; Wood, AJ; Wood, M1
Andurkar, SV; Clark, CR; DeRuiter, J; Huber, T; Valaer, AK1

Reviews

1 review(s) available for fentanyl and noralfentanil

ArticleYear
Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance.
    Anesthesiology, 1992, Volume: 77, Issue:3

    Topics: Alfentanil; Benzoflavones; Cytochrome P-450 Enzyme System; Drug Interactions; Fentanyl; Humans; Microsomes, Liver

1992

Other Studies

6 other study(ies) available for fentanyl and noralfentanil

ArticleYear
Detection of picogram levels of sufentanil by capillary gas chromatography.
    Anesthesiology, 1985, Volume: 63, Issue:6

    Topics: Adult; Biotransformation; Chromatography, Gas; Fentanyl; Humans; Male; Microchemistry; Sufentanil

1985
Is the metabolism of alfentanil subject to debrisoquine polymorphism? A study using human liver microsomes.
    Anesthesiology, 1988, Volume: 69, Issue:4

    Topics: Alfentanil; Chromatography, High Pressure Liquid; Debrisoquin; Fentanyl; Humans; Hydroxylation; Isoquinolines; Liver; Metabolism, Inborn Errors; Microsomes; Osmolar Concentration

1988
Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:4

    Topics: Alfentanil; Blotting, Western; Catalysis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dealkylation; DNA Probes; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases

1995
Determination of alfentanil and noralfentanil in human plasma by gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1994, Aug-05, Volume: 658, Issue:1

    Topics: Alfentanil; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; Quality Control

1994
Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:1

    Topics: Analgesics, Opioid; Animals; Antibodies; Antibody Specificity; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Erythromycin; Fentanyl; Humans; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Norpregnenes; Rabbits; Sufentanil; Troleandomycin

1996
Development of a gas chromatographic-mass spectrometric drug screening method for the N-dealkylated metabolites of fentanyl, sufentanil, and alfentanil.
    Journal of chromatographic science, 1997, Volume: 35, Issue:10

    Topics: Alfentanil; Analgesics, Opioid; Drug Residues; Fentanyl; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Sensitivity and Specificity; Sufentanil

1997