fentanyl has been researched along with nalmefene in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| DiFazio, CA; Dixon, R; Gal, TJ | 1 |
| DiFazio, CA; Gal, TJ | 1 |
| Osifchin, E; Veng-Pedersen, P; Waters, SJ; Wilhelm, JA; Zakszewski, TB | 2 |
| Civelek, AC; Dannals, RF; Dixon, RB; Joh, T; Kao, PF; Kim, S; Ravert, HT; Villemagne, VL; Wagner, HN | 1 |
| Dougherty, TB; Porche, VH; Thall, PF | 1 |
| Burns, MM; Chumpa, A; Kaplan, RL; Shannon, MW | 1 |
| Aalto, S; Hagelberg, N; Hietala, J; Ingman, K; Juhakoski, A; Kallio, A; Karhuvaara, S; Någren, K; Oikonen, V; Scheinin, H | 1 |
| Dong, H; Gao, X; Gong, Z; Ma, W; Su, R; Yong, Z | 1 |
| Chen, Y; Fu, C; Hu, R; Huang, C; Jiang, H; Li, C; Sun, Y; Tang, D; Wang, H; Yan, J; Zhu, J | 1 |
| Cao, H; Dai, F; Liu, Y; Lu, H; Shan, G; Yin, D | 1 |
7 trial(s) available for fentanyl and nalmefene
| Article | Year |
|---|---|
Prolonged blockade of opioid effect with oral nalmefene.
Topics: Administration, Oral; Adult; Analgesia; Clinical Trials as Topic; Double-Blind Method; Fentanyl; Humans; Male; Naltrexone; Narcotic Antagonists; Respiration; Time Factors | 1986 |
Prolonged antagonism of opioid action with intravenous nalmefene in man.
Topics: Adult; Drug Interactions; Fentanyl; Humans; Male; Muscle Rigidity; Naltrexone; Pain; Respiration; Tidal Volume; Time Factors | 1986 |
Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system.
Topics: Adult; Analgesics, Opioid; Brain; Carbon Radioisotopes; Cross-Over Studies; Female; Fentanyl; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Time Factors; Tomography, Emission-Computed | 1997 |
Maximum tolerated dose of nalmefene in patients receiving epidural fentanyl and dilute bupivacaine for postoperative analgesia.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Fentanyl; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Pain, Postoperative | 2000 |
Nalmefene for elective reversal of procedural sedation in children.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Antidotes; Child; Child, Preschool; Emergency Medical Services; Female; Fentanyl; Humans; Infant; Male; Midazolam; Naltrexone; Narcotic Antagonists | 2001 |
Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing.
Topics: Adolescent; Adult; Analgesics, Opioid; Area Under Curve; Caudate Nucleus; Electrocardiography; Fentanyl; Glucuronides; Humans; Male; Naltrexone; Narcotic Antagonists; Positron-Emission Tomography; Prefrontal Cortex; Receptors, Opioid, mu; Thalamus | 2005 |
Low-dose nalmefene pretreatment reduces etomidate-induced myoclonus: A randomized, double-blind controlled trial.
Topics: Anesthesia, General; Cough; Drug-Related Side Effects and Adverse Reactions; Etomidate; Fentanyl; Humans; Myoclonus; Saline Solution | 2023 |
8 other study(ies) available for fentanyl and nalmefene
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Duration of opioid antagonism by nalmefene and naloxone in the dog: an integrated pharmacokinetic/pharmacodynamic comparison.
Topics: Animals; Blood Gas Monitoring, Transcutaneous; Dogs; Female; Fentanyl; Infusions, Intravenous; Models, Biological; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Respiration | 1995 |
Duration of opioid antagonism by nalmefene and naloxone in the dog. A nonparametric pharmacodynamic comparison based on generalized cross-validated spline estimation.
Topics: Analysis of Variance; Animals; Carbon Dioxide; Computer Simulation; Cross-Over Studies; Dogs; Drug Tolerance; Fentanyl; Injections, Intravenous; Male; Models, Statistical; Naloxone; Naltrexone; Narcotic Antagonists; Respiratory Insufficiency; Time Factors | 1995 |
Nalmefene reverses carfentanil-induced loss of righting reflex and respiratory depression in rats.
Topics: Analgesics, Opioid; Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Fentanyl; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Reflex, Righting; Respiratory Insufficiency; Time Factors | 2014 |
GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats.
Topics: Adjuvants, Anesthesia; Allosteric Regulation; Analgesia; Anesthesia; Animals; Delayed Emergence from Anesthesia; Dexmedetomidine; Drug Combinations; Drug Evaluation, Preclinical; Female; Fentanyl; Flumazenil; GABA-A Receptor Antagonists; Ketamine; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nociception; Pain Measurement; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Rotarod Performance Test | 2020 |