fentanyl and flumazenil

fentanyl has been researched along with flumazenil in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199011 (25.00)18.7374
1990's21 (47.73)18.2507
2000's6 (13.64)29.6817
2010's5 (11.36)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Amberger, M; Prag, H; Tolksdorf, W; Vorwold, M1
Chakrabarti, MK; Galletly, DC; Wang, C; Whitwam, JG1
Baktai, G; Kovács, L; Márialigeti, T; Székely, E1
Gent, JP; Goodchild, CS; Serrao, JM1
Boulter, N; Gent, JP; Goodchild, CS; Serrao, JM1
Behne, M1
Cruccu, G; Fabbri, A; Ferracuti, S; Leardi, MG; Manfredi, M1
Besnard, M; Cohen, Y; Merlin, L1
Kataja, J; Kaukinen, L; Kaukinen, S1
Fassoulaki, A; Vassiliou, M1
Achtari, R; Baasch, K; Schaer, H1
Bayer-Berger, M; Chiolero, R; Freeman, J; Godat, L; Ravussin, PA1
Chakalova, E; Chernev, Ch; Gergova, L; Mincheva-Saeva, M; Smilov, I; Vlaĭkova, M1
Edwards, M; Gent, JP; Goodchild, CS; Serrao, JM1
Garamvölgyi, G; Hamar, O1
Hug, CC; Schwieger, IM; Szlam, F1
Hall, RI; Hug, CC; Schwieger, IM; Szlam, F1
Delva, E; Just, B; Lienhart, A1
Corradini, S; Fantera, A; Fegiz, A; Iannarone, C; Talarico, A; Tellan, G1
Bremer, H; Tokic, B; Tolksdorf, W1
Garamvölgyi, G; Hamar, O; Kálmán, A1
Hartvig, P; Nilsson, A; Persson, MP2
Bovill, JG; Breimer, LT; Hennis, PJ; Spierdijk, J1
Ferguson, AH; Juhl, O; Klausen, NO; Neumann, PB; Sørensen, J1
Hole, A; Nilsen, OG; Raeder, JC1
Mora, CT; Torjman, M; White, PF1
Fujigaki, T; Makita, T; Nakamura, H; Shibata, O; Sumikawa, K; Tsujita, T1
Ginsberg, B; Glass, PS; Jhaveri, RM; Ossey, K1
Close, JM; Finder, RL; Moore, PA1
Decoo, D; Destée, A1
Braselton, WE; Cook, RA; Dierenfeld, ES; House, C; Karesh, WB; Puche, H; Torres, A; Uhart, MM1
Hellyer, PW; Kollias-Baker, C; Mama, KR; Shafford, HL; Wagner, AE1
Cappell, MS1
Baker, B; Raphael, D; Rinehart, JB1
Barnett, S; Falchuk, ZM; Hung, A; Leffler, DA; Marshall, J; Sawhney, M1
Arras, M; Cesarovic, N; Fleischmann, T; Henke, J; Jirkof, P1
Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K1
Chen, Y; Fu, C; Hu, R; Huang, C; Jiang, H; Li, C; Sun, Y; Tang, D; Wang, H; Yan, J; Zhu, J1

Reviews

4 review(s) available for fentanyl and flumazenil

ArticleYear
Pharmacology and pharmacokinetics of stereoisomers in radiopharmacy.
    Acta radiologica. Supplementum, 1990, Volume: 374

    Topics: Carbon Radioisotopes; Deoxyglucose; Fentanyl; Flumazenil; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Ketanserin; Methionine; Stereoisomerism; Tomography, Emission-Computed

1990
PET studies in epilepsy.
    Acta neurologica Belgica, 1997, Volume: 97, Issue:3

    Topics: Brain; Carbon Radioisotopes; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fentanyl; Flumazenil; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1997
Sedation and analgesia for gastrointestinal endoscopy during pregnancy.
    Gastrointestinal endoscopy clinics of North America, 2006, Volume: 16, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Diazepam; Endoscopy, Gastrointestinal; Female; Fentanyl; Fetus; Flumazenil; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Meperidine; Naloxone; Pregnancy; Propofol; Risk Assessment; Triage

2006
Review of Intranasally Administered Medications for Use in the Emergency Department.
    The Journal of emergency medicine, 2017, Volume: 53, Issue:1

    Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics

2017

Trials

18 trial(s) available for fentanyl and flumazenil

ArticleYear
[The action of flumazenil in combination with fentanyl on spontaneous respiration].
    Der Anaesthesist, 1992, Volume: 41, Issue:7

    Topics: Adult; Depression, Chemical; Double-Blind Method; Drug Combinations; Fentanyl; Flumazenil; Humans; Male; Respiration

1992
Use of midazolam ('Dormicum') and flumazenil ('Anexate') in paediatric bronchology.
    Current medical research and opinion, 1992, Volume: 12, Issue:9

    Topics: Anesthesia; Atropine; Bronchoscopy; Child, Preschool; Chronic Disease; Drug Administration Schedule; Electrocardiography; Feasibility Studies; Female; Fentanyl; Flumazenil; Humans; Infant; Lung Diseases; Male; Midazolam; Nitrous Oxide; Oxygen; Premedication; Pulse; Succinylcholine

1992
[The effect of flumazenil on alfentanyl-induced respiratory depression].
    Der Anaesthesist, 1991, Volume: 40, Issue:5

    Topics: Adult; Depression, Chemical; Drug Interactions; Fentanyl; Flumazenil; Humans; Injections, Intravenous; Male; Respiration

1991
Nociceptive quality of the orbicularis oculi reflexes as evaluated by distinct opiate- and benzodiazepine-induced changes in man.
    Brain research, 1991, Aug-16, Volume: 556, Issue:2

    Topics: Adult; Blinking; Diazepam; Electric Stimulation; Electromyography; Fentanyl; Flumazenil; Humans; Naloxone; Nociceptors; Placebos

1991
Antagonism of benzodiazepine-fentanyl anaesthesia with flumazenil.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Anti-Anxiety Agents; Double-Blind Method; Female; Fentanyl; Flumazenil; Flunitrazepam; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication; Randomized Controlled Trials as Topic

1990
[Antagonism of flunitrazepam and fentanyl by flumazenil, naloxone or nalbuphine].
    Der Anaesthesist, 1990, Volume: 39, Issue:1

    Topics: Adult; Double-Blind Method; Fentanyl; Flumazenil; Flunitrazepam; Humans; Middle Aged; Morphinans; Nalbuphine; Naloxone; Randomized Controlled Trials as Topic; Respiratory Insufficiency

1990
[Clinical evaluation of the efficacy of Ro 15-1788, Anexate after balanced intravenous anesthesia with flunitrazepam and fentanyl].
    Minerva anestesiologica, 1989, Volume: 55, Issue:6

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Clinical Trials as Topic; Drug Evaluation; Female; Fentanyl; Flumazenil; Flunitrazepam; Humans; Male; Middle Aged; Postoperative Period

1989
[Postoperative, opiate-induced respiratory depression is not dependent on arousal].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1989, Volume: 24, Issue:2

    Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Arousal; Arthroscopy; Clinical Trials as Topic; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Oxygen; Postoperative Complications; Reflex, Startle; Respiration; Vecuronium Bromide

1989
Fentanyl-midazolam-flumazenil anesthesia for induced abortion.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1989, Volume: 30, Issue:1

    Topics: Abortion, Induced; Adolescent; Adult; Ambulatory Care Facilities; Anesthesia Recovery Period; Diazepam; Drug Therapy, Combination; Female; Fentanyl; Flumazenil; Humans; Ketamine; Meperidine; Midazolam; Pain Measurement; Pregnancy; Random Allocation

1989
Effects of flumazenil on post-operative recovery after total intravenous anesthesia with midazolam and alfentanil.
    European journal of anaesthesiology. Supplement, 1988, Volume: 2

    Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Female; Fentanyl; Flumazenil; Humans; Hysterectomy; Midazolam; Postoperative Period; Receptors, GABA-A

1988
The efficacy of flumazenil versus physostigmine after midazolam-alfentanil anaesthesia in man.
    European journal of anaesthesiology. Supplement, 1988, Volume: 2

    Topics: Adult; Alfentanil; Anesthesia; Anesthesia Recovery Period; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Nitrous Oxide; Physostigmine; Random Allocation; Vecuronium Bromide

1988
Flumazenil in total intravenous anaesthesia using midazolam and fentanyl.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:5

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Clinical Trials as Topic; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Middle Aged; Random Allocation

1988
Effects of the benzodiazepine antagonist flumazenil on postoperative performance following total intravenous anaesthesia with midazolam and alfentanil.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:6

    Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Cooperative Behavior; Female; Fentanyl; Flumazenil; Humans; Memory; Midazolam; Nitrous Oxide; Orientation; Postoperative Period; Thiopental

1988
Pharmacokinetics of midazolam and alfentanil in outpatient general anesthesia. A study with concomitant thiopentone, flumazenil or placebo administration.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:6

    Topics: Adult; Alfentanil; Ambulatory Surgical Procedures; Anesthesia, General; Female; Fentanyl; Flumazenil; Humans; Midazolam; Middle Aged; Nitrous Oxide; Placebos; Preanesthetic Medication; Thiopental; Time Factors

1988
Sedative and ventilatory effects of midazolam infusion: effect of flumazenil reversal.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:8

    Topics: Adult; Ambulatory Care; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Hypercapnia; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Pulmonary Alveoli; Respiration; Respiratory Dead Space; Sodium Chloride; Tidal Volume

1995
Evaluation of flumazenil for reversing the effects of midazolam-induced conscious sedation or general anesthesia.
    Southern medical journal, 1993, Volume: 86, Issue:11

    Topics: Adult; Anesthesia, General; Conscious Sedation; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Mental Recall; Midazolam; Middle Aged; Multivariate Analysis; Psychomotor Performance; Wakefulness

1993
Flumazenil reversal of conscious sedation induced with intravenous fentanyl and diazepam.
    Anesthesia progress, 1995, Volume: 42, Issue:1

    Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Intravenous; Conscious Sedation; Diazepam; Double-Blind Method; Female; Fentanyl; Flumazenil; GABA Antagonists; Humans; Hypnotics and Sedatives; Male; Middle Aged

1995
Injection anaesthesia with fentanyl-midazolam-medetomidine in adult female mice: importance of antagonization and perioperative care.
    Laboratory animals, 2016, Volume: 50, Issue:4

    Topics: Analgesics; Anesthetics, Combined; Animals; Body Temperature; Female; Fentanyl; Flumazenil; Heart Rate; Imidazoles; Injections, Intraperitoneal; Medetomidine; Mice; Mice, Inbred C57BL; Midazolam; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Perioperative Care

2016

Other Studies

22 other study(ies) available for fentanyl and flumazenil

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Relative effects of intrathecal administration of fentanyl and midazolam on A delta and C fibre reflexes.
    Neuropharmacology, 1992, Volume: 31, Issue:5

    Topics: Anesthesia, Spinal; Animals; Dogs; Electric Stimulation; Fentanyl; Flumazenil; Kidney; Midazolam; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Sympathetic Nervous System; Tibial Nerve

1992
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:5

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Injections, Spinal; Lumbar Vertebrae; Male; Midazolam; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds

1991
Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:5

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Chlordiazepoxide; Dose-Response Relationship, Drug; Electric Stimulation; Fentanyl; Flumazenil; Injections, Spinal; Male; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds

1991
[Flumazenil and respiratory depression induced by midazolam-fentanyl or midazolam-nalbuphine combinations].
    Cahiers d'anesthesiologie, 1991, Volume: 39, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Depression, Chemical; Female; Fentanyl; Flumazenil; Humans; Mastectomy; Midazolam; Nalbuphine; Respiration

1991
[Flumazenil and peroperative awakening in surgery of scoliosis].
    Annales francaises d'anesthesie et de reanimation, 1990, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Child; Female; Fentanyl; Flumazenil; Hemodynamics; Humans; Intraoperative Care; Male; Midazolam; Middle Aged; Paralysis; Scoliosis

1990
[Anesthesia with dormicum-aneksat in obstetrical-gynecological operations].
    Akusherstvo i ginekologiia, 1990, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Anesthesia, Intravenous; Anesthesia, Obstetrical; Drug Evaluation; Female; Fentanyl; Flumazenil; Humans; Midazolam; Middle Aged; Minor Surgical Procedures; Preanesthetic Medication; Pregnancy

1990
On the mechanism by which midazolam causes spinally mediated analgesia.
    Anesthesiology, 1990, Volume: 73, Issue:2

    Topics: Analgesia, Epidural; Animals; Bicuculline; Cyclazocine; Dose-Response Relationship, Drug; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Male; Midazolam; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds

1990
Fentanyl-midazolam-flumazenil anaesthesia during induced abortion.
    Acta chirurgica Hungarica, 1990, Volume: 31, Issue:1

    Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Female; Fentanyl; Flumazenil; Humans; Ketamine; Midazolam

1990
Absence of agonistic or antagonistic effect of flumazenil (Ro 15-1788) in dogs anesthetized with enflurane, isoflurane, or fentanyl-enflurane.
    Anesthesiology, 1989, Volume: 70, Issue:3

    Topics: Anesthesia, Intravenous; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enflurane; Female; Fentanyl; Flumazenil; Heart Rate; Isoflurane; Male; Time Factors

1989
Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid?
    Anesthesiology, 1989, Volume: 70, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Dogs; Drug Interactions; Enflurane; Fentanyl; Flumazenil; Male; Midazolam; Naloxone; Pulmonary Alveoli; Respiration

1989
[The effect of flumazenil on post-operative oxygen consumption in normothermic and hypothermic patients].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl

    Topics: Female; Fentanyl; Flumazenil; Flunitrazepam; Humans; Hypothermia, Induced; Male; Middle Aged; Oxygen Consumption; Postoperative Period

1989
Effects of intravenous anesthetics on phosphatidylinositol turnover in rat cerebral cortical prisms.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Droperidol; Fentanyl; Flumazenil; Inositol Phosphates; Ketamine; Male; Naloxone; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Wistar; Thiamylal

1994
Health evaluation of free-ranging guanaco (Lama guanicoe).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1998, Volume: 29, Issue:2

    Topics: Analgesics, Opioid; Anesthetics; Animals; Animals, Domestic; Animals, Wild; Antibodies; Antidotes; Blood Chemical Analysis; Camelids, New World; Communicable Diseases; Drug Combinations; Enzymes; Female; Fentanyl; Flumazenil; Health Status; Immobilization; Male; Minerals; Naltrexone; Narcotic Antagonists; Physical Examination; Reference Values; Sheep; Tiletamine; Vitamins; Zolazepam

1998
Effects of diazepam and flumazenil on minimum alveolar concentrations for dogs anesthetized with isoflurane or a combination of isoflurane and fentanyl.
    American journal of veterinary research, 2001, Volume: 62, Issue:4

    Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Anti-Anxiety Agents; Blood Pressure; Body Temperature; Diazepam; Dogs; Drug Interactions; Female; Fentanyl; Flumazenil; GABA Modulators; Heart Rate; Isoflurane; Pulmonary Alveoli

2001
Postoperative global amnesia reversed with flumazenil.
    The neurologist, 2012, Volume: 18, Issue:4

    Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desflurane; Diabetes Mellitus, Type 2; Fentanyl; Flumazenil; GABA Modulators; Humans; Hydromorphone; Isoflurane; Male; Midazolam; Middle Aged; Pancreatitis; Postoperative Complications; Propofol

2012
Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy.
    Journal of clinical gastroenterology, 2016, Volume: 50, Issue:3

    Topics: Age Factors; Anti-Arrhythmia Agents; Antidotes; Atropine; Body Mass Index; Bradycardia; Case-Control Studies; Colonoscopy; Conscious Sedation; Female; Fentanyl; Flumazenil; Health Status; Humans; Hypnotics and Sedatives; Hypotension; Hypoxia; Male; Midazolam; Middle Aged; Naloxone; Narcotic Antagonists; Sex Factors; Treatment Outcome

2016
GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats.
    Scientific reports, 2020, 03-24, Volume: 10, Issue:1

    Topics: Adjuvants, Anesthesia; Allosteric Regulation; Analgesia; Anesthesia; Animals; Delayed Emergence from Anesthesia; Dexmedetomidine; Drug Combinations; Drug Evaluation, Preclinical; Female; Fentanyl; Flumazenil; GABA-A Receptor Antagonists; Ketamine; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nociception; Pain Measurement; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Rotarod Performance Test

2020