fentanyl has been researched along with enkephalin, leucine-2-alanine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (64.71) | 18.7374 |
| 1990's | 11 (32.35) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Fujimoto, JM; Hoffman, RG; Roerig, SC; Takemori, AE; Wilcox, GL | 1 |
| Armstrong, RA; Rooney, KF; Sewell, RD | 1 |
| Ayesta, FJ; Flórez, J | 1 |
| Band, L; Bykov, V; Greig, N; Jacobson, AE; Kim, CH; Newman, A; Rice, KC; Rothman, RB; Xu, H | 1 |
| Yaksh, TL | 1 |
| Stevens, CW; Yaksh, TL | 2 |
| Bykov, V; George, C; Jacobson, AE; Kim, CH; Klee, WA; Long, JB; Mattson, MV; Rice, KC; Rothman, RB; Streaty, RA | 1 |
| Rooney, KF; Sewell, RD | 1 |
| Bowen, WD; Jacobson, AE; Rice, KC; Rodrigues, PA; Wanzor, TE | 1 |
| Durant, PA; Yaksh, TL | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| Brown, DR; Miller, RJ; Vinayek, R | 1 |
| Garzón, J; Herz, A; Schulz, R | 1 |
| Burke, TR; Danks, JA; Herkenham, M; Jacobson, AE; Rice, KC; Rothman, RB | 1 |
| Bykov, V; Jacobson, AE; Long, JB; Rice, KC; Rothman, RB | 1 |
| Bardon, T; Ruckebusch, Y | 1 |
| Bowen, WD; Burke, TR; Bykov, V; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB; Schumacher, UK | 1 |
| Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB | 2 |
| Bardon, T; Pairet, M; Ruckebusch, Y | 1 |
| Rubini, P; Schulz, R; Wüster, M | 1 |
| Herz, A; Schulz, R; Wüster, M | 1 |
| Herz, A; Krenss, H; Schulz, R; Wüster, M | 1 |
| Herz, A; Shearman, GT | 1 |
| Du, C; Ferré, JP; Ruckebusch, Y | 1 |
| Grebenchikov, OA; Likhvantsev, VV; Moroz, VV; Smirnova, VI; Subbotin, VV | 1 |
| Smirnova, VI | 1 |
| Rothe, KS; Stevens, CW | 1 |
| Stevens, CW; Willenbring, S | 1 |
| Brine, GA; Carroll, FI; Chen, C; Lai, J; Liu-Chen, LY; Lu, YF; Partilla, JS; Porreca, F; Rice, KC; Rothman, RB; Sadee, W; Xu, H | 1 |
| Bolling, SF; McNish, R; Romano, MA; Seymour, EM; Traynor, JR | 1 |
34 other study(ies) available for fentanyl and enkephalin, leucine-2-alanine
| Article | Year |
|---|---|
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Isobolographic analysis of analgesic interactions between intrathecally and intracerebroventricularly administered fentanyl, morphine and D-Ala2-D-Leu5-enkephalin in morphine-tolerant and nontolerant mice.
Topics: Animals; Drug Interactions; Drug Tolerance; Enkephalin, Leucine-2-Alanine; Fentanyl; Injections, Intraventricular; Injections, Spinal; Male; Mathematics; Mice; Morphine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1991 |
Increased dopamine receptor sensitivity in the rat following acute administration of sufentanil, U50,488H and D-Ala2-D-Leu5-enkephalin.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzazepines; Corpus Striatum; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Locomotion; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sufentanil; Tritium | 1991 |
Tolerance to the respiratory actions of opiates: withdrawal tolerance and asymmetrical cross-tolerance.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Respiratory System; Substance Withdrawal Syndrome; Sufentanil | 1990 |
The potent opioid agonist, (+)-cis-3-methylfentanyl binds pseudoirreversibly to the opioid receptor complex in vitro and in vivo: evidence for a novel mechanism of action.
Topics: Animals; Brain; Catalepsy; Catatonia; Cell Membrane; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Injections, Intravenous; Male; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1990 |
Substance P release from knee joint afferent terminals: modulation by opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Afferent Pathways; Animals; Capsaicin; Cats; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hindlimb; Joints; Narcotics; Pyrrolidines; Reference Values; Sciatic Nerve; Substance P; Sufentanil | 1988 |
Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
Topics: Analgesics; Animals; Clonidine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Infusions, Parenteral; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Reference Values; Sufentanil | 1989 |
Probes for narcotic receptor mediated phenomena. 15. (3S,4S)-(+)-trans-3-methylfentanyl isothiocyanate, a potent site-directed acylating agent for the delta opioid receptors in vitro.
Topics: Acylation; Adenylyl Cyclase Inhibitors; Analgesia; Animals; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Glioma; Hybrid Cells; Indicators and Reagents; Ligands; Male; Molecular Structure; Neuroblastoma; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 1989 |
Magnitude of opioid dependence after continuous intrathecal infusion of mu- and delta-selective opioids in the rat.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Injections, Spinal; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Substance-Related Disorders; Sufentanil; Time Factors | 1989 |
Evaluation of selective actions of dopamine D-1 and D-2 receptor agonists and antagonists on opioid antinociception.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dopamine Agents; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ergolines; Fentanyl; Injections, Intraventricular; Male; Mice; Narcotics; Nociceptors; Pyrrolidines; Quinpirole; Reaction Time; Receptors, Dopamine; Sufentanil; Sulpiride | 1989 |
Differential coupling of mu-competitive and mu-noncompetitive delta opiate receptors to guanine nucleotide binding proteins in rat brain membranes.
Topics: Adenylate Cyclase Toxin; Alkylating Agents; Animals; Binding, Competitive; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; GTP-Binding Proteins; Intracellular Membranes; Isothiocyanates; Kinetics; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptosomes; Virulence Factors, Bordetella | 1988 |
Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study.
Topics: Analgesia; Analgesics, Opioid; Animals; Behavior, Animal; Bupivacaine; Catheterization; Catheters, Indwelling; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Epidural Space; Fentanyl; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Time Factors | 1986 |
Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique.
Topics: Analgesics, Opioid; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil | 1986 |
Tolerance and cross-tolerance to the antisecretory effects of enkephalins on the guinea-pig ileal mucosa.
Topics: Animals; Biological Transport; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Fentanyl; Guinea Pigs; Ileum; Intestinal Mucosa; Narcotic Antagonists; Receptors, Opioid | 1985 |
Evidence for the epsilon-type of opioid receptor in the rat vas deferens.
Topics: Animals; Binding, Competitive; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Synergism; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Fentanyl; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Vas Deferens | 1985 |
Evidence that the delta-selective alkylating agent, fit, alters the mu-noncompetitive opiate delta binding site.
Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Isothiocyanates; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Intracerebroventricular administration of superFIT and its enantiomer to rats: evidence for in vivo acylation of [3H]DADL binding sites.
Topics: Acylation; Animals; Cerebral Ventricles; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Indicators and Reagents; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism | 1987 |
Comparative effects of opiate agonists on proximal and distal colonic motility in dogs.
Topics: Animals; Colon; Cyclazocine; Dogs; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Fentanyl; Gastrointestinal Motility; Injections, Intravenous; Injections, Spinal; Narcotics; Time Factors | 1985 |
Preparation of rat brain membranes greatly enriched with either type-I-delta or type-II-delta opiate binding sites using site directed alkylating agents: evidence for a two-site allosteric model.
Topics: Alkylating Agents; Allosteric Regulation; Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Male; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates | 1984 |
Ionic conditions differentially affect 3H-DADL binding to type-I and type-II opiate delta receptors in vitro.
Topics: Animals; Brain; Calcium; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Manganese; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Sodium; Thiocyanates | 1984 |
Opioid control of the ruminant stomach motility: functional importance of mu, kappa and delta receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Gastrointestinal Motility; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep; Stomach | 1984 |
The preference of putative pro-enkephalins for different types of opiate receptors.
Topics: Animals; Benzomorphans; Brain; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Morphine; Protein Precursors; Rats; Receptors, Opioid; Vas Deferens | 1981 |
Receptor preference of dynorphin A fragments in the mouse vas deferens determined by different techniques.
Topics: Animals; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Mice; Naloxone; Naltrexone; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding.
Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed | 1984 |
Selective development of tolerance without dependence in multiple opiate receptors of mouse vas deferens.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Humans; Male; Mice; Muscle Contraction; Muscle, Smooth; Receptors, Opioid; Substance-Related Disorders; Sufentanil; Vas Deferens | 1980 |
D-Ala2,D-Leu5-enkephalin generalizes to a discriminative stimulus produced by fentanyl but not ethylketocyclazocine.
Topics: Animals; Cyclazocine; Discrimination, Psychological; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Fentanyl; Generalization, Stimulus; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
In vivo modulation of intestinal motility and sites of opioid effects in the rat.
Topics: Animals; Electrophysiology; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Gastrointestinal Motility; Intestine, Small; Male; Rats; Rats, Inbred Strains | 1984 |
[Intraoperative monitoring of abdominal organs under combined general anesthesia].
Topics: Abdomen; Analgesics, Opioid; Anesthesia, General; Anesthetics; Butorphanol; Enkephalin, Leucine-2-Alanine; Evoked Potentials, Somatosensory; Fentanyl; Humans; Monitoring, Intraoperative; Neuroleptanalgesia; Sympatholytics; Time Factors | 1993 |
[Anesthesia and infusion-transfusion therapy in extensive combined surgeries].
Topics: Analgesics, Opioid; Anesthesia, Endotracheal; Anesthesia, Epidural; Anesthesia, Intravenous; Combined Modality Therapy; Droperidol; Enkephalin, Leucine-2-Alanine; Fentanyl; Heart Diseases; Hemodilution; Humans; Intestinal Diseases; Ketamine; Surgical Procedures, Operative; Sympatholytics | 1993 |
Supraspinal administration of opioids with selectivity for mu-, delta- and kappa-opioid receptors produces analgesia in amphibians.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzofurans; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Fentanyl; Injections, Intraventricular; Male; Morphine; Naltrexone; Narcotics; Pyrrolidines; Rana pipiens; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Spinal mu, delta and kappa opioids alter chemical, mechanical and thermal sensitivities in amphibians.
Topics: Analgesics, Opioid; Animals; Drug Interactions; Enkephalin, Leucine-2-Alanine; Fentanyl; Injections, Spinal; Morphine; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Pain Threshold; Rana pipiens; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sensitivity and Specificity; Spinal Cord | 1997 |
Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor.
Topics: Affinity Labels; Analgesics; Analgesics, Opioid; Animals; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Fentanyl; Melphalan; Membrane Proteins; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Opioid, mu; Recombinant Fusion Proteins; Stereoisomerism | 1998 |
Differential effects of opioid peptides on myocardial ischemic tolerance.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptation, Physiological; Animals; Cardiotonic Agents; Enkephalin, Leucine-2-Alanine; Fentanyl; Heart; In Vitro Techniques; Microscopy, Electron; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Opioid Peptides; Oxygen Consumption; Rabbits; Recovery of Function | 2004 |