fentanyl and cimetidine

fentanyl has been researched along with cimetidine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E1
Gamse, R; Saria, A1
Doenicke, A; Duka, T; Hoehe, M; Matussek, N; Stephan, U1
Dai, S; Ho, MM; Ogle, CW1
Bradley, EL; Fowler, KC; Gelman, S; Tverskoy, M1
Akins, CW; Moss, J; Philbin, DM; Rosenberger, JL; Rosow, CE1
Lauven, PM; Schüttler, J; Schwilden, H; Stoeckel, H1

Trials

2 trial(s) available for fentanyl and cimetidine

ArticleYear
Influence of the histaminergic system on opiate-induced neurosecretion and behaviour.
    Psychoneuroendocrinology, 1987, Volume: 12, Issue:4

    Topics: Adult; Affect; Behavior; Blood Glucose; Cimetidine; Dimethindene; Fentanyl; Growth Hormone; Histamine; Humans; Hydrocortisone; Male; Norepinephrine; Prolactin; Radioimmunoassay

1987
Histamine release with intravenous narcotics: protective effects of H1 and H2-receptor antagonists.
    Klinische Wochenschrift, 1982, Sep-01, Volume: 60, Issue:17

    Topics: Cimetidine; Diphenhydramine; Double-Blind Method; Fentanyl; Hemodynamics; Histamine Release; Humans; Morphine; Phenylephrine; Random Allocation

1982

Other Studies

13 other study(ies) available for fentanyl and cimetidine

ArticleYear
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
    Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine

2016
Antidromic vasodilatation in the rat hindpaw measured by laser Doppler flowmetry: pharmacological modulation.
    Journal of the autonomic nervous system, 1987, Volume: 19, Issue:2

    Topics: Adrenergic Fibers; Animals; Capsaicin; Cimetidine; Electric Stimulation; Enkephalin, Methionine; Female; Fentanyl; Hindlimb; Lasers; Male; Naloxone; Pyrilamine; Rats; Regional Blood Flow; Rheology; Skin; Vasodilation

1987
Morphine enhances gastric mucus synthesis in rats.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: Animals; Atropine; Cimetidine; Fentanyl; Gastric Mucosa; Male; Morphine; Mucus; Naloxone; Rats

1986
Influence of fentanyl and morphine on intestinal circulation.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:6

    Topics: Animals; Blood Gas Analysis; Cesium Radioisotopes; Cimetidine; Dogs; Drug Interactions; Fentanyl; Hydrogen-Ion Concentration; Injections, Intravenous; Intestine, Small; Microspheres; Morphine; Oxygen Consumption; Pentobarbital; Phentolamine; Promethazine; Radioisotopes; Regional Blood Flow; Rubidium; Vascular Resistance; Vasoconstriction

1985
[Prevention of fentanyl rebound by administration of cimetidine (author's transl)].
    Der Anaesthesist, 1981, Volume: 30, Issue:9

    Topics: Adult; Anesthesia; Biotransformation; Cimetidine; Fentanyl; Guanidines; Humans; Hydrogen-Ion Concentration; Kinetics; Middle Aged; Time Factors

1981