Page last updated: 2024-08-24

fenofibric acid and gemfibrozil

fenofibric acid has been researched along with gemfibrozil in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's4 (30.77)18.2507
2000's4 (30.77)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T1
Chalmers, DK; Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T; Wielens, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brinkjost, T; Ehrt, C; Koch, O1
Kashihara, M; Mizuguchi, M; Yokoyama, T1
Santafé Oroz, J; Segarra Domènech, J1
Betteridge, L; Chan, P; Gallagher, K; Munro, E; Patel, M; Schachter, M; Sever, P; Wolfe, J1
Walsh, KB; Wang, C1
Kockx, M; Kooistra, T; Princen, HM1
Eriksson, P; Hamsten, A; Nilsson, L; Takemura, T1
Bauman, JN; Davis, JA; Goosen, TC; Hurst, SI; Loi, CM; Williams, JA; Yu, C1
Chen, J; Li, C; Lu, Y; Peijnenburg, WJGM; Qu, J; Xie, Q; Zhang, YN; Zhao, J; Zhou, Y1

Reviews

2 review(s) available for fenofibric acid and gemfibrozil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pharmacologic therapy of atherosclerosis (I). Current possibilities].
    Medicina clinica, 1983, Nov-26, Volume: 81, Issue:17

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Clofibrate; Clofibric Acid; Fenofibrate; Gemfibrozil; Glycosaminoglycans; Humans; Ion Exchange Resins; Lipoproteins; Nicotinic Acids; Pentanoic Acids; Probucol

1983

Other Studies

11 other study(ies) available for fenofibric acid and gemfibrozil

ArticleYear
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity

2008
Probing the fibrate binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Animals; Binding Sites; Carboxylic Acids; Clofibric Acid; Esters; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Ligands; Liver; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Thermodynamics

2009
Impact of Binding Site Comparisons on Medicinal Chemistry and Rational Molecular Design.
    Journal of medicinal chemistry, 2016, 05-12, Volume: 59, Issue:9

    Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Models, Chemical; Proteins

2016
Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.
    Journal of medicinal chemistry, 2021, 10-14, Volume: 64, Issue:19

    Topics: Amyloid Neuropathies, Familial; Anthelmintics; Bithionol; Crystallography, X-Ray; Drug Repositioning; Humans; Prealbumin; Thermodynamics; Triclabendazole

2021
Growth inhibition of human vascular smooth muscle cells by fenofibrate: a possible therapy for restenosis.
    Cardiovascular research, 1994, Volume: 28, Issue:5

    Topics: Bezafibrate; Cell Division; Cells, Cultured; Clofibrate; Fenofibrate; Gemfibrozil; Graft Occlusion, Vascular; Humans; Muscle, Smooth; Platelet-Derived Growth Factor; Saphenous Vein

1994
Effect of chloride channel blockers on the cardiac CFTR chloride and L-type calcium currents.
    Cardiovascular research, 1996, Volume: 32, Issue:2

    Topics: Animals; Anthracenes; Calcium; Calcium Channel Blockers; Chloride Channels; Chlorides; Clofibric Acid; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Fenofibrate; Gemfibrozil; Glycolates; Guinea Pigs; Ion Transport; Mice; Myocardium; ortho-Aminobenzoates; Patch-Clamp Techniques; Stilbenes

1996
Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.
    Thrombosis and haemostasis, 1998, Volume: 80, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Alitretinoin; Animals; Apolipoprotein A-I; Cells, Cultured; Clofibrate; Clofibric Acid; Dimerization; Female; Fenofibrate; Fibric Acids; Fibrinogen; Gemfibrozil; Gene Expression Regulation; Genes, Reporter; Hypolipidemic Agents; Liver; Macaca fascicularis; Male; Peroxisome Proliferators; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Tretinoin

1998
Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:6

    Topics: Bezafibrate; Cells, Cultured; Clofibric Acid; Endothelium, Vascular; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Plasminogen Activator Inhibitor 1; Pyrimidines; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription, Genetic

1999
Choice of lipid-regulating drugs.
    The Medical letter on drugs and therapeutics, 2001, May-28, Volume: 43, Issue:1105

    Topics: Apolipoproteins; Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Drug Interactions; Drug Therapy, Combination; Fenofibrate; Fish Oils; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Muscular Diseases; Niacin; Triglycerides

2001
Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Anticholesteremic Agents; Area Under Curve; Atorvastatin; Catalysis; Drug Interactions; Fenofibrate; Gemfibrozil; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lactones; Microsomes, Liver; Models, Biological; Molecular Structure; Pyrroles; Recombinant Proteins; Tandem Mass Spectrometry; Uridine Diphosphate Glucuronic Acid

2007
Unveiling the important roles of coexisting contaminants on photochemical transformations of pharmaceuticals: Fibrate drugs as a case study.
    Journal of hazardous materials, 2018, 09-15, Volume: 358

    Topics: China; Fenofibrate; Gemfibrozil; Hydrogen-Ion Concentration; Light; Models, Theoretical; Molecular Structure; Pharmaceutical Preparations; Photolysis; Rivers; Water Pollutants, Chemical

2018