fenofibrate and ursodeoxycholic acid

fenofibrate has been researched along with ursodeoxycholic acid in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (11.11)	29.6817
2010's	23 (63.89)	24.3611
2020's	9 (25.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ohira, H; Sata, M; Sato, Y; Ueno, T	1
Dohmen, K; Ishibashi, H; Mizuta, T; Nakamuta, M; Shimohashi, N; Yamamoto, K	1
Abiru, S; Daikoku, M; Dohmen, K; Ishibashi, H; Komori, A; Nagaoka, S; Ueki, T; Wen, CY; Yano, K; Yatsuhashi, H	1
Bassendine, MF; Jones, DE; Newton, J; Walker, LJ	1
Cabrera, R; Clark, V; Firpi, RJ; Keach, J; Levy, C; Lindor, K; Morelli, G; Nelson, DR; Peter, JA; Petz, J; Soldevila-Pico, C	1
Fauler, G; Fickert, P; Frank, S; Guelly, C; Gumhold, J; Höfler, G; Kratky, D; Lass, A; Magnes, C; Moustafa, T; Reicher, H; Sattler, W; Silbert, D; Sinner, F; Thueringer, A; Trauner, M; Zechner, R	1
Bian, ZL; Han, XF; Liu, Y; Ma, X; Qiu, DK; Wang, QX; You, ZR	1
Bélénotti, P; Benyamine, A; Ene, N; Grandval, P; Guervilly, C; Laugier, R; Papazian, L; Petit, P; Serratrice, J; Weiller, PJ	1
Dohmen, K; Haruno, M; Tanaka, H	1
Elshazly, SM; Mahmoud, AA	1
Chen, K; Guo, C; He, L; Li, J; Li, S; Liu, T; Lu, J; Lu, W; Wang, F; Wang, J; Xia, Y; Yin, Q; Zhang, Y; Zheng, Y; Zhou, Y	1
Cheung, AC; Feld, JJ; Hirschfield, GM; Janssen, HL; Kowgier, M; Lapointe-Shaw, L; Meza-Cardona, J	1
Czul, F; Levy, C	1
Hansen, BE; Jones, DE	1
Cheung, AC; Feld, JJ; Kowgier, M	1
Dyson, JK; Hegade, VS; Jones, DEJ; Khanna, A; Walker, LJ; Wong, LL	1
Strassburg, CP	1
Duan, W; Jia, J; Ma, H; Ou, X; Wang, Q; Wang, X; Wang, Y; Wu, X; You, H; Zhang, W; Zhao, X	1
Ben Belkacem, K; Chazouillères, O; Corpechot, C; Gaouar, F; Housset, C; Kemgang Fankem, AD; Lemoinne, S; Pares, A; Poupon, R; Reig, A	1
Bahar, R; Bowlus, CL; Liu, CH; Wong, KA	1
Chazouillères, O; Corpechot, C; Lemoinne, S; Rousseau, A	1
Abdalla, SM; Clark, V; Dejman, A; Levy, C	1
Chang, Y; Cho, EJ; Chung, SW; Kim, MA; Kim, SW; Kim, YJ; Lee, HY; Lee, JH; Lee, YB; Leem, G; Park, JY; Yoon, JH; Yoon, JS; Yu, SJ	1
Assis, DN; Auclair, AM; Boyer, JL; de la Rosa Rodriguez, R; Gallucci, GM; Ghonem, NS; Hemme, CL	1
Han, Y; Liu, Y; Sun, K; Tian, A; Wang, L; Zhang, M; Zhou, X	1
Assis, DN; Barbier, O; Boyer, JL; Gallucci, GM; Ghonem, NS; Hemme, C; Trottier, J	1
Dohmen, K; Harada, S; Onohara, SY	1
Ardakani, MJE; Gholami, S; Hassani, AH; Hatami, B; Mosala, M; Zali, MR	1
Deng, J; Ding, D; Guo, C; Guo, G; Han, Y; Jia, G; Liu, Y; Shang, Y; Sun, R; Wang, X; Zheng, L	1
Chen, Y; Duan, Y; Han, J; Liu, L; Yang, S; Yang, X; Zhang, S	1
Deng, J; Ding, D; Guo, G; Han, Y; Jia, G; Liu, Y; Ren, P; Shang, Y; Sun, R; Wang, X; Yang, C; Zheng, L; Zhou, X	1
Cui, L; Deng, J; Guo, C; Guo, G; Han, Y; Jia, G; Liu, Y; Shang, Y; Sun, R; Wang, X; Yang, C; Zheng, L	1

Reviews

5 review(s) available for fenofibrate and ursodeoxycholic acid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis. Drug design, development and therapy, 2015, Volume: 9 Topics: Cholagogues and Choleretics; Drug Therapy, Combination; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Middle Aged; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid	2015
Novel Therapies on Primary Biliary Cirrhosis. Clinics in liver disease, 2016, Volume: 20, Issue:1 Topics: Abatacept; Anti-Retroviral Agents; Antibodies, Monoclonal, Humanized; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Fenofibrate; Glucocorticoids; Humans; Hypolipidemic Agents; Immunologic Factors; Liver Cirrhosis, Biliary; Mesenchymal Stem Cell Transplantation; Receptors, Cytoplasmic and Nuclear; Rituximab; Ursodeoxycholic Acid; Ustekinumab	2016
[Modern treatment of primary biliary cholangitis]. Der Internist, 2018, Volume: 59, Issue:1 Topics: Bezafibrate; Budesonide; Chenodeoxycholic Acid; Cohort Studies; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Multicenter Studies as Topic; PPAR alpha; Pregnancy; Prognosis; Quality of Life; Receptors, Cytoplasmic and Nuclear; Risk Assessment; Treatment Outcome; Ursodeoxycholic Acid	2018
Current Treatment Options for Primary Biliary Cholangitis. Clinics in liver disease, 2018, Volume: 22, Issue:3 Topics: Alkaline Phosphatase; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Comorbidity; Drug Therapy, Combination; Fenofibrate; Fibroblast Growth Factors; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Malnutrition; Osteoporosis; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid	2018

Trials

4 trial(s) available for fenofibrate and ursodeoxycholic acid

Article	Year
Fenofibrate for patients with asymptomatic primary biliary cirrhosis. World journal of gastroenterology, 2004, Mar-15, Volume: 10, Issue:6 Topics: Adult; Aged; Cholagogues and Choleretics; Female; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Retreatment; Treatment Failure; Treatment Outcome; Ursodeoxycholic Acid	2004
Efficacy of fenofibrate in Chinese patients with primary biliary cirrhosis partially responding to ursodeoxycholic acid therapy. Journal of digestive diseases, 2012, Volume: 13, Issue:4 Topics: Asian People; Biomarkers; Cholagogues and Choleretics; Drug Therapy, Combination; Female; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Treatment Outcome; Ursodeoxycholic Acid	2012
Fenofibrate in primary sclerosing cholangitis; a randomized, double-blind, placebo-controlled trial. Pharmacology research & perspectives, 2022, Volume: 10, Issue:4 Topics: Adult; Alkaline Phosphatase; Bilirubin; Cholangitis, Sclerosing; Female; Fenofibrate; Humans; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid	2022
Effectiveness of Fenofibrate in Treatment-Naive Patients With Primary Biliary Cholangitis: A Randomized Clinical Trial. The American journal of gastroenterology, 2023, 11-01, Volume: 118, Issue:11 Topics: Cholagogues and Choleretics; Drug Therapy, Combination; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Prospective Studies; Treatment Outcome; Ursodeoxycholic Acid	2023

Other Studies

27 other study(ies) available for fenofibrate and ursodeoxycholic acid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Fenofibrate treatment in patients with primary biliary cirrhosis. The American journal of gastroenterology, 2002, Volume: 97, Issue:8 Topics: Cholagogues and Choleretics; Drug Therapy, Combination; Female; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Statistics, Nonparametric; Treatment Outcome; Ursodeoxycholic Acid	2002
Fenofibrate-induced liver injury. World journal of gastroenterology, 2005, Dec-28, Volume: 11, Issue:48 Topics: Aged; Female; Fenofibrate; Humans; Liver; Liver Cirrhosis, Biliary; PPAR alpha; Ursodeoxycholic Acid	2005
Comment on biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:1 Topics: Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Drug Synergism; Fenofibrate; Humans; Immunoglobulin M; Liver Cirrhosis, Biliary; Prognosis; Ursodeoxycholic Acid	2009
Pilot study: fenofibrate for patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid. Alimentary pharmacology & therapeutics, 2011, Volume: 33, Issue:2 Topics: Adult; Aged; Cholagogues and Choleretics; Drug Therapy, Combination; Female; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Pilot Projects; Statistics as Topic; Treatment Outcome; Ursodeoxycholic Acid	2011
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury. Gastroenterology, 2012, Volume: 142, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile Acids and Salts; Cell Proliferation; Cholestasis, Intrahepatic; Chronic Disease; Dietary Fats; Disease Models, Animal; Disease Progression; Fatty Acids; Female; Fenofibrate; Gene Expression Profiling; Gene Expression Regulation; Hepatitis; Hypolipidemic Agents; Lipid Metabolism; Liver; Liver Cirrhosis; Metabolomics; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; PPAR gamma; Pregnancy; Prenatal Exposure Delayed Effects; Triglycerides; Ursodeoxycholic Acid	2012
[Ischemic cholangitis in intensive care unit: favourable outcome with ursodesoxycholic acid and fenofibrate]. La Revue de medecine interne, 2013, Volume: 34, Issue:2 Topics: Cholagogues and Choleretics; Cholangitis, Sclerosing; Critical Care; Fenofibrate; Humans; Hypolipidemic Agents; Intensive Care Units; Male; Middle Aged; Treatment Outcome; Ursodeoxycholic Acid	2013
Effectiveness of fenofibrate in comparison to bezafibrate for patients with asymptomatic primary biliary cirrhosis. Fukuoka igaku zasshi = Hukuoka acta medica, 2013, Volume: 104, Issue:10 Topics: Adult; Aged; Asymptomatic Diseases; Bezafibrate; Cardiovascular Diseases; Cholesterol, LDL; Cohort Studies; Drug Therapy, Combination; Dyslipidemias; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; PPAR alpha; Prognosis; Renal Insufficiency; Retrospective Studies; Risk Factors; Uric Acid; Ursodeoxycholic Acid	2013
Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats. PloS one, 2014, Volume: 9, Issue:9 Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Fenofibrate; Fructose; Glutathione; Glycation End Products, Advanced; Insulin; Insulin Resistance; Male; Malondialdehyde; Metabolic Syndrome; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Triglycerides; Uric Acid; Ursodeoxycholic Acid	2014
Combined ursodeoxycholic acid (UDCA) and fenofibrate in primary biliary cholangitis patients with incomplete UDCA response may improve outcomes. Alimentary pharmacology & therapeutics, 2016, Volume: 43, Issue:2 Topics: Adult; Aged; Alkaline Phosphatase; Bilirubin; Cholagogues and Choleretics; Cohort Studies; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Ursodeoxycholic Acid	2016
Editorial: fenofibrate as second-line therapy in high risk PBC--more answers or more questions? Alimentary pharmacology & therapeutics, 2016, Volume: 43, Issue:5 Topics: Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Ursodeoxycholic Acid	2016
Editorial: fenofibrate as second-line therapy in high risk PBC--more answers or more questions? Authors' reply. Alimentary pharmacology & therapeutics, 2016, Volume: 43, Issue:5 Topics: Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Ursodeoxycholic Acid	2016
Long-Term Fenofibrate Treatment in Primary Biliary Cholangitis Improves Biochemistry but Not the UK-PBC Risk Score. Digestive diseases and sciences, 2016, Volume: 61, Issue:10 Topics: Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Cholagogues and Choleretics; Cohort Studies; Creatinine; Drug Therapy, Combination; Female; Fenofibrate; Glomerular Filtration Rate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Longitudinal Studies; Middle Aged; Prognosis; Retrospective Studies; Serum Albumin; Time Factors; Treatment Outcome; Ursodeoxycholic Acid	2016
Efficacy and safety of fenofibrate add-on therapy for patients with primary biliary cholangitis and a suboptimal response to UDCA. Revista espanola de enfermedades digestivas, 2018, Volume: 110, Issue:9 Topics: Adult; Aged; Cholagogues and Choleretics; Cholangitis; Cohort Studies; Drug Therapy, Combination; Female; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Male; Middle Aged; Retrospective Studies; Ursodeoxycholic Acid	2018
Primary sclerosing cholangitis response to the combination of fibrates with ursodeoxycholic acid: French-Spanish experience. Clinics and research in hepatology and gastroenterology, 2018, Volume: 42, Issue:6 Topics: Adult; Aged; Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Cholangitis, Sclerosing; Drug Therapy, Combination; Female; Fenofibrate; France; Humans; Hypolipidemic Agents; Liver Function Tests; Male; Middle Aged; Pruritus; Retrospective Studies; Spain; Ursodeoxycholic Acid; Young Adult	2018
Letter: reduction in projected mortality or need for liver transplantation associated with bezafibrate add-on in primary biliary cholangitis with incomplete UDCA response. Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:2 Topics: Bezafibrate; Cholangitis; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Ursodeoxycholic Acid	2019
Use of Fenofibrate for patients with primary Sclerosing Cholangitis. Clinics and research in hepatology and gastroenterology, 2019, Volume: 43, Issue:3 Topics: Cholangitis, Sclerosing; Fenofibrate; Fibric Acids; Humans; Ursodeoxycholic Acid	2019
Additional fibrate treatment in UDCA-refractory PBC patients. Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:9 Topics: Alkaline Phosphatase; Bezafibrate; Cholagogues and Choleretics; Drug Therapy, Combination; Female; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Ursodeoxycholic Acid	2019
Fenofibrate Improves Liver Function and Reduces the Toxicity of the Bile Acid Pool in Patients With Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Who Are Partial Responders to Ursodiol. Clinical pharmacology and therapeutics, 2020, Volume: 108, Issue:6 Topics: Adult; Aged; Bile Acids and Salts; Biomarkers; Cholangitis, Sclerosing; Cytokines; Drug Therapy, Combination; Female; Fenofibrate; Humans; Inflammation Mediators; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; PPAR alpha; Principal Component Analysis; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid; Young Adult	2020
Fenofibrate improves GLOBE and UK-PBC scores and histological features in primary biliary cholangitis. Minerva medica, 2022, Volume: 113, Issue:6 Topics: Cholagogues and Choleretics; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Retrospective Studies; Ursodeoxycholic Acid	2022
Adjunct Fenofibrate Up-regulates Bile Acid Glucuronidation and Improves Treatment Response For Patients With Cholestasis. Hepatology communications, 2021, Volume: 5, Issue:12 Topics: Adult; Bile Acids and Salts; Cholangitis, Sclerosing; Cholestasis; Drug Therapy, Combination; Female; Fenofibrate; Glucuronides; Hepatocytes; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; PPAR alpha; Retrospective Studies; Treatment Outcome; Up-Regulation; Ursodeoxycholic Acid; Young Adult	2021
Effects of Switching from Fenofibrate to Pemafibrate for Asymptomatic Primary Biliary Cholangitis. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2021, 10-25, Volume: 78, Issue:4 Topics: Benzoxazoles; Butyrates; Fenofibrate; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid	2021
Efficacy and safety of fenofibrate addition therapy in patients with cirrhotic primary biliary cholangitis with incomplete response to ursodeoxycholic acid. Hepatology communications, 2022, Volume: 6, Issue:12 Topics: Alkaline Phosphatase; Cholagogues and Choleretics; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid	2022
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate. European journal of pharmacology, 2023, Jan-05, Volume: 938 Topics: Animals; Cholestasis; Fenofibrate; Liver; Mice; Mice, Inbred C57BL; Necrosis; Rosiglitazone; Ursodeoxycholic Acid	2023
Fenofibrate normalizes alkaline phosphatase and improves long-term outcomes in patients with advanced primary biliary cholangitis refractory to ursodeoxycholic acid. Gastroenterologia y hepatologia, 2023, Volume: 46, Issue:9 Topics: Alkaline Phosphatase; Cholagogues and Choleretics; Fenofibrate; Humans; Liver Cirrhosis, Biliary; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid	2023