Compounds > fenofibrate

fenofibrate and gw 9578

fenofibrate has been researched along with gw 9578 in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (14.29)	18.2507
2000's	6 (85.71)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM	1
Barr, RJ; Bean, JS; Bensch, WR; Dominianni, SJ; Huang, N; Kauffman, RF; Luffer-Atlas, D; Maise, DE; Mantlo, NB; Mayhugh, D; Montrose-Rafizadeh, C; Osborne, J; Rungta, D; Saeed, A; Singh, J; Thompson, RC; Wang, X; Xu, Y; Yumibe, NP; Zink, RW	1
Chen, X; Cryan, E; Demarest, KT; Hlasta, DJ; Matthews, JM; Rybczynski, PJ; Strauss, K; Tang, Y; Xu, JZ; Yang, M; Zhou, L	1
Brown, PJ; Chapman, JM; Kliewer, SA; Koble, CS; Lehmann, JM; Lewis, MC; Moore, LB; Plunket, KD; Sundseth, SS; Willson, TM; Wilson, JG; Winegar, DA; Wu, Z	1
Berge, RK; Derudas, B; Fruchart, JC; Gervois, P; Guerre-Millo, M; Herbert, JM; Madsen, L; Poulain, P; Raspé, E; Staels, B; Willson, TM; Winegar, DA	1
Burn, TC; Collier, P; Hollis, G; Huber, R; Liao, B; Link, J; Liu, PC; Mukherjee, R; Schlingmann, KL; Stow, MD; Young, PR	1
Buckley, KA; Chan, BY; Dillon, JP; Fraser, WD; Gallagher, JA; Gartland, A; Wilson, PJ	1

Reviews

1 review(s) available for fenofibrate and gw 9578

Article	Year
The PPARs: from orphan receptors to drug discovery. Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4 Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors	2000

Other Studies

6 other study(ies) available for fenofibrate and gw 9578

Article	Year
Design and synthesis of a potent and selective triazolone-based peroxisome proliferator-activated receptor alpha agonist. Journal of medicinal chemistry, 2003, Nov-20, Volume: 46, Issue:24 Topics: Administration, Oral; Animals; Apolipoprotein A-I; Binding, Competitive; Biological Availability; Cell Line; Dogs; Drug Design; Humans; Mice; Mice, Transgenic; Propionates; Radioligand Assay; Rats; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Transcription Factors; Transfection; Triazoles	2003
Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists. Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24 Topics: Amino Acids; Animals; Butyrates; Combinatorial Chemistry Techniques; Drug Design; Humans; Indans; Mice; Mice, Inbred Strains; Molecular Structure; PPAR alpha; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Urea	2007
A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity. Journal of medicinal chemistry, 1999, Sep-23, Volume: 42, Issue:19 Topics: Animals; Butyrates; DNA-Binding Proteins; Fenofibrate; Humans; Hypolipidemic Agents; Lipid Metabolism; Male; Mice; Nuclear Proteins; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Zinc Fingers	1999
Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity. The Journal of biological chemistry, 2000, Jun-02, Volume: 275, Issue:22 Topics: Adipose Tissue; Animals; Butyrates; Clofibrate; Fenofibrate; Hypolipidemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Phenylurea Compounds; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Transcription Factors	2000
Induction of endogenous genes by peroxisome proliferator activated receptor alpha ligands in a human kidney cell line and in vivo. The Journal of steroid biochemistry and molecular biology, 2003, Volume: 85, Issue:1 Topics: Animals; Butyrates; Cells, Cultured; Cricetinae; Enzyme Activation; Fatty Acids; Fenofibrate; Gene Expression Regulation; Humans; Hypolipidemic Agents; Isoenzymes; Kidney Tubules, Proximal; Ligands; Liver; Male; Membrane Proteins; Mesocricetus; Oligonucleotide Array Sequence Analysis; Perilipin-2; Phenylurea Compounds; Protein Kinases; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Triglycerides	2003
PPAR agonists modulate human osteoclast formation and activity in vitro. Bone, 2007, Volume: 40, Issue:1 Topics: Acetates; Apoptosis; Bezafibrate; Bone Resorption; Butyrates; Cells, Cultured; Fenofibrate; Humans; Hypolipidemic Agents; Leukocytes, Mononuclear; Macrophage Colony-Stimulating Factor; Osteoclasts; Peroxisome Proliferator-Activated Receptors; Phenols; Phenoxyacetates; Phenylurea Compounds; RANK Ligand; RNA, Messenger; Thiazolidinediones; Transcription, Genetic	2007