fenofibrate and folic acid

fenofibrate has been researched along with folic acid in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's8 (50.00)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dierkes, J; Luley, C; Westphal, S2
Banditt, P; Dierkes, J; Kunstmann, S; Lössner, A; Luley, C; Westphal, S1
Ceska, R; Grauová, B; Kozich, V; Melenovský, V; Stulc, T1
Császár, A; Márk, L1
Holubec, L; Mayer, O; Pikner, R; Simon, J; Subrt, I1
Ceska, R; Grauova, B; Haas, T; Hradec, J; Kozich, V; Krijt, J; Malik, J; Melenovsky, V; Stulc, T; Wichterle, D1
Holubec, L; Mayer, O; Pikner, R; Simon, J; Trefil, L1

Reviews

3 review(s) available for fenofibrate and folic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Antilipemic agents in combined therapy].
    Orvosi hetilap, 2002, Aug-25, Volume: 143, Issue:34

    Topics: Anticholesteremic Agents; Apolipoproteins; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Fenofibrate; Fluvastatin; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipids; Pravastatin; Simvastatin; Triglycerides; Vitamin B 12; Vitamin B 6

2002
Fenofibrate-induced hyperhomocysteinaemia: clinical implications and management.
    Drug safety, 2003, Volume: 26, Issue:2

    Topics: Arteriosclerosis; Fenofibrate; Folic Acid; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Kidney; Vitamin B 12

2003

Trials

6 trial(s) available for fenofibrate and folic acid

ArticleYear
Serum homocysteine increases after therapy with fenofibrate or bezafibrate.
    Lancet (London, England), 1999, Jul-17, Volume: 354, Issue:9174

    Topics: Adult; Bezafibrate; Chromatography, High Pressure Liquid; Fenofibrate; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Pilot Projects; Pyridoxine; Vitamin B 12

1999
Vitamin supplementation can markedly reduce the homocysteine elevation induced by fenofibrate.
    Atherosclerosis, 2001, Volume: 158, Issue:1

    Topics: Cross-Over Studies; Double-Blind Method; Fenofibrate; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Pyridoxine; Vitamin B 12; Vitamins

2001
Folate supplementation prevents plasma homocysteine increase after fenofibrate therapy.
    Nutrition (Burbank, Los Angeles County, Calif.), 2001, Volume: 17, Issue:9

    Topics: Arteriosclerosis; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fenofibrate; Folic Acid; Homocysteine; Humans; Hyperlipidemias; Hypolipidemic Agents; Pilot Projects; Risk Factors

2001
Fenofibrate-induced hyperhomocysteinemia may be prevented by folate co-administration.
    European journal of clinical pharmacology, 2003, Volume: 59, Issue:5-6

    Topics: Aged; Anticholesteremic Agents; Cross-Over Studies; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Indoles; Male; Middle Aged; Prospective Studies

2003
Effect of folic acid on fenofibrate-induced elevation of homocysteine and cysteine.
    American heart journal, 2003, Volume: 146, Issue:1

    Topics: Cholesterol; Creatinine; Cysteine; Female; Fenofibrate; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Prospective Studies; Statistics as Topic; Triglycerides; Uric Acid

2003
Folate co-administration improves the effectiveness of fenofibrate to decrease the lipoprotein oxidation and endothelial dysfunction surrogates.
    Physiological research, 2006, Volume: 55, Issue:5

    Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Drug Therapy, Combination; Endothelium, Vascular; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Prospective Studies; Thrombomodulin; Treatment Outcome; Triglycerides; Vitamin B Complex; von Willebrand Factor

2006

Other Studies

7 other study(ies) available for fenofibrate and folic acid

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016