fenfluramine and tryptophan

fenfluramine has been researched along with tryptophan in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199037 (50.68)18.7374
1990's26 (35.62)18.2507
2000's6 (8.22)29.6817
2010's3 (4.11)24.3611
2020's1 (1.37)2.80

Authors

AuthorsStudies
Barrett, AM; McSharry, L1
BARDAKDJIAN, J; Belin, MF; Gonnard, P; Kouyoumdijian, JC1
Wurtman, JJ; Wurtman, RJ2
Knapp, S; Mandell, AJ1
Baran, L; Maj, J; Palider, W1
Fisher, H; Lu, MR; Wagner, GC2
D'Hondt, P; Maes, M; Minner, B; Raus, J; Suy, E; Vandervorst, C1
Fisher, H; Hsu, HC; Wagner, GC1
Brammer, GL; McGuire, MT; Pollack, DB; Raleigh, MJ; Yuwiler, A1
Aisenthal, L; Le Feuvre, RA; Rothwell, NJ1
Kahn, RS; van Praag, HM1
Anderson, GM; Teff, KL; Young, SN1
Schaechter, JD; Wurtman, RJ1
Laferrere, B; Wurtman, RJ1
Goodall, E; Silverstone, T1
Bethea, CL; Richardson, KD; Urban, JH; Van de Kar, LD1
Richardson, KD; Urban, JH; Van de Kar, LD1
Fisher, H; Lee, NS; Trout, JR; Wagner, GC1
Blundell, JE; Hill, AJ1
Aulakh, CS; Garrick, NA; Mueller, EA; Murphy, DL1
Contreras, E; Germany, A; Merino, A1
Braszko, JJ; Maciejewski, A; Majewski, K; Wisniewski, K1
Lerer, B1
Oswald, I1
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P1
Geyer, MA; Knapp, S; Mandell, AJ1
Gessa, GL; Tagliamonte, A1
Costa, E; Groppetti, A; Misher, A; Naimzada, M; Revuelta, A1
Duhault, J; Verdavainne, C1
Balsara, JJ; Chandorkar, AG; Gada, VP; Nandal, NV1
Botting, R; Morinan, A1
Root-Bernstein, RS; Westall, FC1
Anderson, GH; Li, ET1
Matthews, WD; Smith, CD1
Hwang, EC; Van Woert, MH1
Curzon, G1
Dumbrille-Ross, A; Tang, SW1
Contreras, E; Muñoz, M; Quijada, L; Tamayo, L1
Bernasconi, S; Crunelli, V; Samanin, R1
Bordash, GD; Corso, P; Wallnau, LB2
Curzon, G; Fernando, JC1
Cowen, PJ; McTavish, SF; Park, SB; Williamson, DJ1
Borve, T; Fisher, H; Johnson, SK; Pole, N; Wagner, GC1
Cowen, PJ; Fairburn, CG; Franklin, M; Oldman, AD; Walsh, AE1
Lehnert, H; Wurtman, RJ1
Aronson, SC; Barr, LC; Goodman, WK; McDougle, CJ; Price, LH1
Adler, L; Huether, G; Poeggeler, B; Rüther, E1
Andersen, T; Astrup, A; Breum, L; Møller, SE1
Darmani, NA; Reeves, SL1
Carpenter, LL; Epperson, CN; McDougle, CJ; Price, LH1
Curradi, C; Del Bene, E; Salmon, S; Sicuteri, F1
Diksic, M; Mück-Seler, D1
FitzGerald, M; Li, S; Malone, K; Mann, JJ; Suckow, R1
McDougle, CJ1
Coccaro, EF; Cooper, TB; Hauger, R; Kavoussi, RJ1
Baumgarten, HG; Grozdanovic, Z1
Anisman, H; Griffiths, J; Knott, VJ; Merali, Z; Ravindran, AV1
Fisher, H; Halladay, AK; Hsu, T; Sekowski, A; Wagner, GC1
Howson, AL; Knott, VJ; Perugini, M; Ravindran, AV; Young, SN1
Diksic, M; Tohyama, Y; Yamane, F1
Cooper, TB; Finkelstein, DM; Jimerson, DC; Levine, JM; Metzger, ED; Wolfe, BE1
Castell, L; Cowen, PJ; Feldman, E; Peto, T; Sharpley, AL; Vassallo, CM1
Hervé, P; Humbert, M; Nunes, H; Parent, F; Simonneau, G; Sitbon, O1
Fisher, H; Halladay, AK; Hesse, K; Kirschner, E; Wagner, GC1
Joyce, PR; Mulder, RT; Porter, RJ1
Benkelfat, C; Herpertz, SC; Hurley, RA; Johnson, PA; Taber, KH1
Boss-Williams, KA; Weiss, JM; West, CH1
Bolhuis, JE; Güntürkün, O; Kjaer, JB; Kops, MS; Korte, SM; Korte-Bouws, GA; Olivier, B; Westphal, KG1
Arch, JR; Cawthorne, MA; Cripps, RL; D'Agostino, G; Garfield, AS; Heisler, LK; Jovanovic, Z; Martin-Gronert, MS; Ozanne, SE; Stocker, CJ; Wargent, ET; Yeo, GS1
Kim, H; Moon, JH; Oh, CM1

Reviews

12 review(s) available for fenfluramine and tryptophan

ArticleYear
Serotoninergic mechanisms in human feeding: the pharmacological evidence.
    Appetite, 1986, Volume: 7 Suppl

    Topics: Amitriptyline; Antipsychotic Agents; Cyproheptadine; Diet; Feeding Behavior; Fenfluramine; Food Preferences; Humans; Hunger; Metergoline; Methysergide; Nervous System Physiological Phenomena; Obesity; Satiety Response; Serotonin; Synaptic Transmission; Tryptophan; Zimeldine

1986
Do carbohydrates affect food intake via neurotransmitter activity?
    Appetite, 1988, Volume: 11 Suppl 1

    Topics: Animals; Dietary Carbohydrates; Dietary Proteins; Eating; Fenfluramine; Humans; Neurotransmitter Agents; Rats; Serotonin; Taste; Tryptophan

1988
Use of serotonergic agents in the clinical assessment of central serotonin function.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Fenfluramine; Humans; Mental Disorders; Mice; Piperazines; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin; Tryptophan

1986
Alternative therapies for bipolar disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8

    Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid

1985
Amino acid control of neurotransmitter synthesis and release: physiological and clinical implications.
    Psychotherapy and psychosomatics, 1993, Volume: 60, Issue:1

    Topics: Brain; Carbohydrates; Feeding Behavior; Female; Fenfluramine; Humans; Male; Neural Conduction; Neurotransmitter Agents; Prolactin; Serotonin; Tryptophan; Tyrosine

1993
Biological approaches to treatment-resistant obsessive compulsive disorder.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Behavior Therapy; Buspirone; Clonazepam; Combined Modality Therapy; Decision Trees; Drug Therapy, Combination; Electroconvulsive Therapy; Fenfluramine; Humans; Lithium; Obsessive-Compulsive Disorder; Phototherapy; Selective Serotonin Reuptake Inhibitors; Sleep Deprivation; Trazodone; Tryptophan

1993
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.
    Drug safety, 1996, Volume: 15, Issue:2

    Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Buspirone; Child; Clomipramine; Clonazepam; Costs and Cost Analysis; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Lithium; Obsessive-Compulsive Disorder; Paroxetine; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan

1996
Update on pharmacologic management of OCD: agents and augmentation.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 12

    Topics: Clinical Trials as Topic; Clozapine; Dopamine Agents; Drug Therapy, Combination; Female; Fenfluramine; Haloperidol; Humans; Lithium; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Treatment Outcome; Tryptophan

1997
Role of serotonin in obsessive-compulsive disorder.
    The British journal of psychiatry. Supplement, 1998, Issue:35

    Topics: Biogenic Monoamines; Fenfluramine; Humans; Neuropeptides; Obsessive-Compulsive Disorder; Piperazines; Pyrazines; Pyrimidines; Serotonin; Serotonin Syndrome; Synaptic Transmission; Tryptophan

1998
Risk factors for pulmonary arterial hypertension.
    Clinics in chest medicine, 2001, Volume: 22, Issue:3

    Topics: Altitude; Aminorex; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Second-Generation; Appetite Depressants; Brassica; Comorbidity; Eisenmenger Complex; Fatty Acids, Monounsaturated; Female; Fenfluramine; Glycogen Storage Disease; Hematologic Diseases; HIV Infections; Humans; Hypertension, Portal; Hypertension, Pulmonary; Plant Oils; Pregnancy; Pregnancy Complications, Cardiovascular; Rapeseed Oil; Risk Factors; Smoking; Splenectomy; Telangiectasia, Hereditary Hemorrhagic; Thrombosis; Thyroid Diseases; Tryptophan

2001
Understanding emotion regulation in borderline personality disorder: contributions of neuroimaging.
    The Journal of neuropsychiatry and clinical neurosciences, 2003,Fall, Volume: 15, Issue:4

    Topics: Aspartic Acid; Borderline Personality Disorder; Brain; Brain Mapping; Choline; Compulsive Personality Disorder; Creatinine; Depression; Electroencephalography; Emotions; Female; Fenfluramine; Humans; Magnetic Resonance Imaging; Nerve Net; Serotonin Agents; Tomography, Emission-Computed; Tryptophan

2003
Serotonin in the regulation of systemic energy metabolism.
    Journal of diabetes investigation, 2022, Volume: 13, Issue:10

    Topics: Animals; Anti-Obesity Agents; Energy Metabolism; Fenfluramine; Lipids; Receptors, Serotonin; Serotonin; Tryptophan

2022

Trials

5 trial(s) available for fenfluramine and tryptophan

ArticleYear
Effect of valine on 5-HT-mediated prolactin release in healthy volunteers, and on mood in remitted depressed patients.
    The British journal of psychiatry : the journal of mental science, 1995, Volume: 167, Issue:2

    Topics: Adult; Affect; Aged; Amino Acids, Branched-Chain; Amitriptyline; Antidepressive Agents; Blood-Brain Barrier; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Fenfluramine; Humans; Lithium; Male; Middle Aged; Personality Inventory; Prolactin; Recurrence; Reference Values; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan; Valine

1995
Plasma tryptophan levels and prolactin response to fenfluramine in healthy volunteers.
    Biological psychiatry, 1997, Sep-01, Volume: 42, Issue:5

    Topics: Adult; Female; Fenfluramine; Humans; Male; Prolactin; Regression Analysis; Selective Serotonin Reuptake Inhibitors; Tryptophan

1997
The effect of acute tryptophan depletion and fenfluramine on quantitative EEG and mood in healthy male subjects.
    Biological psychiatry, 1999, Jul-15, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Affect; Amino Acids; Bipolar Disorder; Double-Blind Method; Electroencephalography; Fenfluramine; Health Status; Humans; Male; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Single-Blind Method; Tryptophan

1999
Serotonin function following remission from bulimia nervosa.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:3

    Topics: Adult; Amino Acids; Bulimia; Female; Fenfluramine; Hormones; Humans; Placebos; Prolactin; Reference Values; Serotonin; Serotonin Receptor Agonists; Tryptophan

2000
Baseline prolactin and L-tryptophan availability predict response to antidepressant treatment in major depression.
    Psychopharmacology, 2003, Volume: 165, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antidepressive Agents, Tricyclic; Biological Availability; Clomipramine; Depressive Disorder, Major; Desipramine; Double-Blind Method; Female; Fenfluramine; Humans; Hydrocortisone; Male; Menstrual Cycle; Middle Aged; Prolactin; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan

2003

Other Studies

56 other study(ies) available for fenfluramine and tryptophan

ArticleYear
Inhibition of drug-induced anorexia in rats by methysergide.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:12

    Topics: Animals; Anorexia; Appetite; Brain Chemistry; Eating; Fenfluramine; Iproniazid; Male; Mazindol; Methysergide; Rats; Serotonin; Time Factors; Tryptophan

1975
Action of some fluorinated amphetamine-like compounds on the synaptosomal uptake of neurotransmitters.
    Journal of neurochemistry, 1976, Volume: 27, Issue:3

    Topics: Animals; Dopamine; Fenfluramine; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Male; Neurotransmitter Agents; Phenyl Ethers; Propylamines; Rats; Serotonin; Synaptosomes; Tryptophan; Tyrosine

1976
Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats.
    Science (New York, N.Y.), 1977, Dec-16, Volume: 198, Issue:4322

    Topics: Animals; Appetite Depressants; Diet; Dietary Proteins; Energy Intake; Feeding Behavior; Fenfluramine; Male; Neurons; Phenyl Ethers; Propylamines; Rats; Serotonin; Tryptophan

1977
Coincidence of blockade of synaptosomal 5-hydroxytryptamine uptake and decrease in tryptophan hydroxylase activity: effects of fenfluramine.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:1

    Topics: Animals; Brain; Depression, Chemical; Dextroamphetamine; Fenfluramine; Male; Mesencephalon; Mixed Function Oxygenases; Neural Pathways; Rats; Serotonin; Synaptosomes; Tryptophan; Tryptophan Hydroxylase

1976
The effects of serotonergic and antiserotonergic drugs on the flexor reflex of spinal rat: a proposed model to evaluate the action on the central serotonin receptor.
    Journal of neural transmission, 1976, Volume: 38, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anthracenes; Clonidine; Cyproheptadine; Decerebrate State; Fenfluramine; Hindlimb; Lysergic Acid Diethylamide; Male; Metergoline; Muscle Contraction; p-Chloroamphetamine; Piperidines; Rats; Reflex; Serotonin; Tryptophan

1976
Ethanol intake of chickens treated with fenfluramine, fluoxetine, and dietary tryptophan.
    Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:5

    Topics: Alcohol Drinking; Animals; Body Temperature Regulation; Brain; Chickens; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Male; Receptors, Serotonin; Serotonin; Taste; Tryptophan

1992
HPA-axis hormones and prolactin responses to dextro-fenfluramine in depressed patients and healthy controls.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:6

    Topics: Adrenocorticotropic Hormone; Brain Chemistry; Depressive Disorder; Dexamethasone; Endorphins; Fenfluramine; Hormones; Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Prolactin; Psychiatric Status Rating Scales; Serotonin; Stereoisomerism; Tryptophan

1991
Suppression of ethanol intake in chickens by fenfluramine and dietary tryptophan.
    Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:6

    Topics: Alcohol Drinking; Animals; Body Temperature Regulation; Brain; Chickens; Dose-Response Relationship, Drug; Fenfluramine; Male; Serotonin; Tryptophan

1991
Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys.
    Brain research, 1991, Sep-20, Volume: 559, Issue:2

    Topics: Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Cyproheptadine; Fenfluramine; Fluoxetine; Male; Serotonin; Social Dominance; Tryptophan

1991
Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds.
    Brain research, 1991, Aug-02, Volume: 555, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature Regulation; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Feeding Behavior; Fenfluramine; In Vitro Techniques; Injections, Intraventricular; Male; Oxygen Consumption; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1991
Panic disorder: a presynaptic serotonin defect?
    Psychiatry research, 1990, Volume: 31, Issue:2

    Topics: Anxiety Disorders; Brain; Fear; Fenfluramine; Humans; Panic; Receptors, Serotonin; Serotonin; Synapses; Tryptophan

1990
Serotonin in cisternal cerebrospinal fluid of the rat: measurement and use as an index of functionally active serotonin.
    Life sciences, 1987, Jun-08, Volume: 40, Issue:23

    Topics: Amitriptyline; Animals; Brain Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Male; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1987
Effect of chronic D-fenfluramine administration on rat hypothalamic serotonin levels and release.
    Life sciences, 1989, Volume: 44, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Fenfluramine; Hydroxyindoleacetic Acid; Hypothalamus; Kinetics; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1989
Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats.
    Brain research, 1989, Dec-18, Volume: 504, Issue:2

    Topics: Anesthesia; Animals; Brain; Fenfluramine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1989
Pharmacological studies on the serotoninergic and nonserotonin-mediated stimulation of prolactin and corticosterone secretion by fenfluramine. Effects of pretreatment with fluoxetine, indalpine, PCPA, and L-tryptophan.
    Neuroendocrinology, 1985, Volume: 41, Issue:4

    Topics: Animals; Antidepressive Agents; Corticosterone; Fenclonine; Fenfluramine; Fluoxetine; Kinetics; Male; Piperidines; Prolactin; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1985
Serotonin and norepinephrine-dependent effects of fenfluramine on plasma renin activity in conscious male rats.
    Neuropharmacology, 1985, Volume: 24, Issue:6

    Topics: Animals; Blood Pressure; Desipramine; Dose-Response Relationship, Drug; Fenclonine; Fenfluramine; Fluoxetine; Heart Rate; Male; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Renin; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan

1985
Fenfluramine-induced behavior changes in rats prefed serotonin-altering amounts of tryptophan and pyridoxine.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Diet; Drug Interactions; Fenfluramine; Male; Pyridoxine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1988
Serotoninergic modulation of the pattern of eating and the profile of hunger-satiety in humans.
    International journal of obesity, 1987, Volume: 11 Suppl 3

    Topics: Adolescent; Adult; Feeding Behavior; Female; Fenfluramine; Food Preferences; Humans; Hunger; Male; Receptors, Serotonin; Satiation; Tryptophan

1987
Serotonergic and adrenergic mechanisms in tolerance development to ethanol and barbital.
    Cellular and molecular biology, 1987, Volume: 33, Issue:1

    Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Ethanol; Fenfluramine; Levodopa; Male; Mice; Norepinephrine; Phenoxybenzamine; Serotonin; Sleep; Tryptophan

1987
Effect of angiotensin II on some behavioral and neurochemical measures of the central serotonine system.
    Biomedica biochimica acta, 1985, Volume: 44, Issue:9

    Topics: 5-Hydroxytryptophan; Angiotensin II; Animals; Behavior, Animal; Brain Chemistry; Cyproheptadine; Electroshock; Fenfluramine; Hydroxylation; Injections, Intraventricular; Kinetics; Male; Mianserin; Physostigmine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1985
Sleep.
    Experimental medicine and surgery, 1969, Volume: 27, Issue:1-2

    Topics: Amobarbital; Appetite Depressants; Barbiturates; Dreams; Electroencephalography; Fenfluramine; Fluorine; Humans; Methysergide; Narcolepsy; Phenethylamines; Sleep; Sleep Stages; Sleep, REM; Substance-Related Disorders; Time Factors; Tranylcypromine; Tryptophan

1969
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine

1971
Effects of amphetamines on regional tryptophan hydroxylase activity and synaptosomal conversion of tryptophan to 5-hydroxytryptamine in rat brain.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Amphetamine; Animals; Brain; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Dextroamphetamine; Fenfluramine; Histocytochemistry; In Vitro Techniques; Kinetics; Male; Mesencephalon; Methamphetamine; Microscopy, Fluorescence; Mixed Function Oxygenases; Nerve Endings; Rats; Serotonin; Subcellular Fractions; Sucrose; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase

1974
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase

1974
Evidence that in rats 1-benzyl- -methoxy-3-trifluoromethylphenethylamine (SK& F 1-39728) dissociates anorexia from central stimulation and actions on brain monoamine stores.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:3

    Topics: Animals; Appetite; Appetite Depressants; Benzyl Compounds; Biogenic Amines; Body Temperature; Brain; Brain Chemistry; Central Nervous System; Dextroamphetamine; Dopamine; Fenfluramine; Fluorine; Kinetics; Male; Motor Activity; Norepinephrine; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Tritium; Tryptophan; Tyrosine

1972
[Modification of the cerebral serotonin level in the rat by trifluoromethyl-2-phenyl ethyl aminopropane (Fenfluramine 768 S)].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 170, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Appetite Depressants; Brain; Brain Chemistry; Carboxy-Lyases; Dopa Decarboxylase; Epididymis; Fenfluramine; Heart; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Rats; Serotonin; Tryptophan

1967
Psychopharmacological investigation of the monoamine oxidase inhibitory activity of molindone, a dihydroindolone neuroleptic.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Blepharoptosis; Catalepsy; Fenclonine; Fenfluramine; Humans; Indoles; Levodopa; Male; Mice; Molindone; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Reserpine; Stereotyped Behavior; Tryptamines; Tryptophan

1984
Involvement of 5-hydroxytryptamine in the analgesic action of pethidine and morphine in mice.
    British journal of pharmacology, 1982, Volume: 75, Issue:4

    Topics: Analgesics; Animals; Body Temperature; Brain Chemistry; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Meperidine; Mice; Morphine; Reaction Time; Serotonin; Tryptophan

1982
Fenfluramine binds 5-hydroxytryptophan.
    Brain research bulletin, 1984, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Serotonin; Structure-Activity Relationship; Tryptophan

1984
5-Hydroxytryptamine : a modulator of food composition but not quantity?
    Life sciences, 1984, Jun-18, Volume: 34, Issue:25

    Topics: Animals; Brain Chemistry; Dietary Carbohydrates; Dietary Proteins; Fenclonine; Fenfluramine; Food Preferences; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1984
Pharmacological profile of a model for central serotonin receptor activation.
    Life sciences, 1980, Apr-28, Volume: 26, Issue:17

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Fenfluramine; Humans; Male; Methoxydimethyltryptamines; Models, Biological; Quinolines; Quipazine; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Synaptic Transmission; Tryptophan

1980
Comparative effects of various serotonin releasing agents in mice.
    Biochemical pharmacology, 1980, Dec-01, Volume: 29, Issue:23

    Topics: 5,6-Dihydroxytryptamine; Amphetamines; Animals; Behavior, Animal; Fenclonine; Fenfluramine; Male; Mice; p-Chloroamphetamine; Phenethylamines; Serotonin; Synaptosomes; Tryptophan; Tyramine

1980
Some behavioural interactions between 5-hydroxytryptamine and dopamine.
    Advances in experimental medicine and biology, 1981, Volume: 133

    Topics: Animals; Behavior, Animal; Dextroamphetamine; Dopamine; Fenclonine; Fenfluramine; Metergoline; Motor Activity; p-Chloroamphetamine; Rats; Serotonin; Tryptophan

1981
Manipulations of synaptic serotonin: discrepancy of effects on serotonin S1 and S2 sites.
    Life sciences, 1983, Jun-06, Volume: 32, Issue:23

    Topics: Animals; Cerebral Cortex; Fenfluramine; Fluoxetine; Male; Rats; Receptors, Serotonin; Serotonin; Spiperone; Tryptophan

1983
Decrease of tolerance and physical dependence on morphine by drugs affecting brain serotonin.
    Cellular and molecular biology, including cyto-enzymology, 1980, Volume: 26, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Fenfluramine; Humans; Mice; Morphine Dependence; Naloxone; Rats; Serotonin; Serotonin Antagonists; Tryptophan

1980
Effects of d- and 1-fenfluramine on striatal homovanillic acid concentrations in rats after pharmacological manipulation of brain serotonin.
    Pharmacological research communications, 1980, Volume: 12, Issue:3

    Topics: Animals; Apomorphine; Brain; Corpus Striatum; Female; Fenfluramine; Haloperidol; Homovanillic Acid; Humans; Methylphenidate; Phenylacetates; Rats; Serotonin; Stereoisomerism; Stereotyped Behavior; Tryptophan

1980
The effects of tryptophan and manipulations of serotonergic receptors on tonic immobility in chickens.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:4

    Topics: Animals; Catalepsy; Chickens; Cinanserin; Fenfluramine; Humans; Immobilization; p-Chloroamphetamine; Quipazine; Raphe Nuclei; Receptors, Serotonin; Tryptophan

1981
Tonic immobility in domestic fowl: possible interaction of serotonergic and dopaminergic mechanisms.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:4

    Topics: Animals; Apomorphine; Catalepsy; Chickens; Fenfluramine; Haloperidol; Humans; Immobilization; Receptors, Dopamine; Receptors, Serotonin; Tryptophan

1981
Behavioural responses to drugs releasing 5-hydroxytryptamine and catecholamines: effects of treatments altering precursor concentrations in brain.
    Neuropharmacology, 1981, Volume: 20, Issue:2

    Topics: Amino Acids; Animals; Behavior, Animal; Brain Chemistry; Catecholamines; Dextroamphetamine; Fenfluramine; Male; p-Chloroamphetamine; Rats; Serotonin; Tryptophan; Tyrosine

1981
Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression.
    Journal of studies on alcohol. Supplement, 1993, Volume: 11

    Topics: Aggression; Animals; Behavior, Animal; Brain; Drug Synergism; Ethanol; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Mice; Tryptophan

1993
Dieting decreases plasma tryptophan and increases the prolactin response to d-fenfluramine in women but not men.
    Journal of affective disorders, 1995, Feb-21, Volume: 33, Issue:2

    Topics: Adult; Analysis of Variance; Brain; Diet, Reducing; Female; Fenfluramine; Humans; Male; Prolactin; Reproducibility of Results; Serotonin; Sex Characteristics; Tryptophan

1995
Effects of indirectly acting 5-HT receptor agonists on circulating melatonin levels in rats.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Fenfluramine; Fluoxetine; Injections, Intraperitoneal; Male; Melatonin; Pargyline; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin Receptor Agonists; Tryptophan

1993
Ethanol consumption following acute fenfluramine, fluoxetine, and dietary tryptophan.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:4

    Topics: Alcohol Drinking; Animals; Diet; Dose-Response Relationship, Drug; Drinking Behavior; Energy Intake; Fenfluramine; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Serotonin; Sucrose; Tryptophan

1993
Long-term effect of dexfenfluramine on amino acid profiles and food selection in obese patients during weight loss.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1996, Volume: 20, Issue:2

    Topics: Adult; Amino Acids; Appetite Depressants; Dietary Fats; Dietary Proteins; Female; Fenfluramine; Food Preferences; Humans; Male; Obesity; Tryptophan; Tyrosine; Weight Loss

1996
The mechanism by which the selective 5-HT1A receptor antagonist S-(-) UH 301 produces head-twitches in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:1

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fenfluramine; Head Movements; Male; Mice; Mice, Inbred ICR; Presynaptic Terminals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Vesicles; Tryptophan

1996
The possible role of tryptophan in migraine.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Adult; Blood Platelets; Female; Fenfluramine; Humans; Male; Migraine Disorders; Regression Analysis; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

1996
DL-fenfluramine increases the 5-HT synthesis rate in the terminals while decreasing it in the cell bodies of the rat brain.
    Brain research, 1996, Oct-21, Volume: 737, Issue:1-2

    Topics: Animals; Autoradiography; Axons; Brain; Fenfluramine; Male; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Stereoisomerism; Tryptophan

1996
Acute tryptophan depletion attenuates the prolactin response to d-fenfluramine challenge in healthy human subjects.
    Psychopharmacology, 1998, Volume: 138, Issue:1

    Topics: Adult; Fenfluramine; Humans; Male; Middle Aged; Prolactin; Selective Serotonin Reuptake Inhibitors; Tryptophan

1998
Influence of acute tryptophan depletion on mood and immune measures in healthy males.
    Psychoneuroendocrinology, 1999, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Affect; Amino Acids; Cell Division; Depression; Fenfluramine; Humans; Interleukin-1; Interleukin-6; Lymphocyte Activation; Male; Psychological Tests; Psychoneuroimmunology; Serotonin; Single-Blind Method; Tryptophan

1999
Differential effects of monoaminergic agonists on alcohol intake in rats fed a tryptophan-enhanced diet.
    Alcohol (Fayetteville, N.Y.), 1999, Volume: 18, Issue:1

    Topics: Alcohol Drinking; Amphetamine; Animals; Appetite Depressants; Cerebral Cortex; Corpus Striatum; Dopamine; Fenfluramine; Food, Formulated; Hypothalamus; Phentermine; Rats; Rats, Long-Evans; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1999
Acute and chronic D-fenfluramine treatments have different effects on serotonin synthesis rates in the rat brain: an autoradiographic study.
    Neurochemical research, 1999, Volume: 24, Issue:12

    Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Caudate Nucleus; Cerebral Cortex; Drug Administration Schedule; Fenfluramine; Male; Organ Specificity; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Tryptophan

1999
Decreased tryptophan availability but normal post-synaptic 5-HT2c receptor sensitivity in chronic fatigue syndrome.
    Psychological medicine, 2001, Volume: 31, Issue:4

    Topics: Adult; Fatigue Syndrome, Chronic; Female; Fenfluramine; Humans; Male; Middle Aged; Piperazines; Prolactin; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Synaptic Membranes; Tryptophan

2001
Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Clorgyline; Corpus Striatum; Dopamine; Drug Interactions; Fenclonine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists; Tryptophan

2001
Effects of fenfluramine, 8-OH-DPAT, and tryptophan-enriched diet on the high-ethanol intake by rats bred for susceptibility to stress.
    Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Animals; Antidepressive Agents, Second-Generation; Breeding; Diet; Disease Models, Animal; Eating; Escape Reaction; Ethanol; Fenfluramine; Male; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Stress, Psychological; Swimming; Tryptophan

2011
Serotonin release in the caudal nidopallium of adult laying hens genetically selected for high and low feather pecking behavior: an in vivo microdialysis study.
    Behavioural brain research, 2014, Jul-15, Volume: 268

    Topics: Animals; Behavior, Animal; Blood Chemical Analysis; Brain; Chickens; Feathers; Female; Fenfluramine; Hydroxyindoleacetic Acid; Microdialysis; Serotonin; Serotonin Agents; Species Specificity; Tryptophan

2014
5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats.
    Disease models & mechanisms, 2016, Volume: 9, Issue:4

    Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Body Weight; Dietary Proteins; Feeding Behavior; Female; Fenfluramine; Fetus; Growth and Development; Hypothalamus; Laser Capture Microdissection; Male; Neurons; Oligonucleotide Array Sequence Analysis; Organ Size; Pregnancy; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reproducibility of Results; Serotonin; Time Factors; Tryptophan

2016