felodipine and ramipril

felodipine has been researched along with ramipril in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (57.58)18.2507
2000's9 (27.27)29.6817
2010's5 (15.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sun, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Huysmans, FT; Koene, RA; Sluiter, HE; van Hamersvelt, HW; Wetzels, JF1
Bainbridge, AD; Lees, KR; MacFadyen, RJ; Reid, JL1
Foale, RA; MacKay, J; Mayet, J; Nicolaides, A; Poulter, NR; Sever, PS; Shahi, M; Sinclair, AM; Stanton, AV; Thom, SA1
Huysmans, FT; Kloke, HJ; Koene, RA; van Hamersvelt, HW; Wetzels, JF1
Hartford, M; Ljungman, S; Siewert-Delle, A; Wikstrand, J1
Edgar, B; Hasselgren, B; Johnsson, G; Rönn, O1
Foale, RA; Mayet, J; McGrath, K; Poulter, NR; Sever, PS; Shahi, M; Thom, SA1
Hoffmann, W; Hopmeier, P; Schernthaner, G; Schnack, C1
Bauer, B; Poisson, P; Rangoonwala, B; Schueler, E1
Karppanen, H; Laakso, J; Malmberg, L; Mervaala, EM; Teräväinen, TL; Vapaatalo, H2
Sawicki, PT1
Bech, JN; Hansen, HE; Jensen, KT; Kornerup, HJ; Nielsen, CB; Pedersen, EB; Spencer, ES; Sølling, J1
Cacciapuoti, F; Capasso, A; De Nicola, A; Gentile, S; Minicucci, F; Mirra, G1
Hishikawa, K; Lüscher, TF1
Bauer, B; Massaro, J; Scholze, J1
Ariff, B; Chapman, N; Foale, RA; Mayet, J; Poulter, NR; Sever, PS; Shahi, M; Thom, SA; Wasan, B1
Aurell, M; Bernheim, J; Boner, G; Chanard, J; Harris, K; Herlitz, H; Risler, T1
Bainbridge, AD; Lees, KR; Macfadyen, RJ; Reid, JL; Stark, S1
Cvetković, RS; Plosker, GL1
Bida, M; Dörffel, Y; Hansen, A; Juncken, D; Rangoonwala, B; Ritz, A; Schnitker, J; Scholze, J1
Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T1
Borbas, E; Handrock, R; Klebs, S; Schaetzl, R; Trenkwalder, P1
Hammad, MA; Mohamed, AA; Mohamed, AM; Omar, MA1

Reviews

2 review(s) available for felodipine and ramipril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Ramipril/felodipine extended-release fixed-dose combination: a review of its use in the management of essential hypertension.
    Drugs, 2005, Volume: 65, Issue:13

    Topics: Antihypertensive Agents; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Drug Interactions; Felodipine; Humans; Hypertension; Ramipril; Renal Insufficiency

2005

Trials

18 trial(s) available for felodipine and ramipril

ArticleYear
Is natriuresis on felodipine due to reversal of the renal effects of angiotensin II?
    Kidney international. Supplement, 1992, Volume: 36

    Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bridged Bicyclo Compounds; Double-Blind Method; Felodipine; Humans; Kidney; Male; Natriuresis; Ramipril

1992
A study of the acute pharmacodynamic interaction of ramipril and felodipine in normotensive subjects.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Bridged Bicyclo Compounds; Double-Blind Method; Drug Interactions; Electrolytes; Felodipine; Heart Rate; Humans; Male; Norepinephrine; Peptidyl-Dipeptidase A; Ramipril; Random Allocation; Renin

1991
Angiotensin converting enzyme inhibition does not prevent the natriuretic effect of felodipine.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:3

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Chlorides; Double-Blind Method; Felodipine; Hemodynamics; Humans; Male; Natriuresis; Potassium; Ramipril; Renal Circulation; Sodium

1993
Effects of intensified blood-pressure reduction on renal function and albumin excretion in primary hypertension. Addition of felodipine or ramipril to long-term treatment with beta-blockade.
    American journal of hypertension, 1995, Volume: 8, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Albuminuria; Blood Pressure; Drug Therapy, Combination; Felodipine; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Ramipril

1995
The acute haemodynamic and renal effects of oral felodipine and ramipril in healthy subjects.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:4

    Topics: Administration, Oral; Adult; Blood Pressure; Diuresis; Double-Blind Method; Felodipine; Forearm; Heart Rate; Hemodynamics; Humans; Kidney; Male; Potassium; Ramipril; Regional Blood Flow; Renal Circulation; Vascular Resistance

1993
Left ventricular hypertrophy and QT dispersion in hypertension.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:5

    Topics: Adult; Antihypertensive Agents; Echocardiography; Electrocardiography; Felodipine; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Ramipril

1996
Renal and metabolic effects of 1-year treatment with ramipril or atenolol in NIDDM patients with microalbuminuria.
    Diabetologia, 1996, Volume: 39, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Pressure; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Felodipine; Female; Humans; Kidney; Male; Middle Aged; Prospective Studies; Ramipril; Vasodilator Agents

1996
Ramipril and felodipine: a comparison of the efficacy and safety of monotherapy versus combination therapy.
    Current medical research and opinion, 1996, Volume: 13, Issue:8

    Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Severity of Illness Index

1996
Stabilization of glomerular filtration rate over 2 years in patients with diabetic nephropathy under intensified therapy regimens. Diabetes Treatment and Teaching Programmes Working Group.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:9

    Topics: Adult; Antihypertensive Agents; Diabetic Nephropathies; Felodipine; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Inulin; Male; Metoprolol; Middle Aged; Prospective Studies; Ramipril; Time Factors

1997
[New therapeutic principle in the management of hypertension].
    Der Internist, 1996, Volume: 37, Issue:4 Suppl Ne

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cohort Studies; Diuretics; Double-Blind Method; Felodipine; Humans; Hypertension; Ramipril

1996
A comparison of the effect of ramipril, felodipine and placebo on glomerular filtration rate, albuminuria, blood pressure and vasoactive hormones in chronic glomerulonephritis. A randomized, prospective, double-blind, placebo-controlled study over two yea
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:8

    Topics: Adolescent; Adult; Aged; Albuminuria; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Endothelins; Felodipine; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Male; Middle Aged; Placebos; Prospective Studies; Ramipril

1997
Prevention of left ventricular hypertrophy by ACE-inhibitor, ramipril in comparison with calcium-channel antagonist, felodipine.
    International journal of cardiology, 1998, Jan-31, Volume: 63, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Echocardiography; Felodipine; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Prognosis; Prospective Studies; Ramipril; Treatment Outcome

1998
Antihypertensive profiles with ascending dose combinations of ramipril and felodipine ER.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1999, Volume: 21, Issue:8

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Safety; Single-Blind Method; Treatment Outcome

1999
The effects of an ACE inhibitor and a calcium antagonist on the progression of renal disease: the Nephros Study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:11

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Disease Progression; Drug Combinations; Felodipine; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Middle Aged; Prospective Studies; Ramipril

2001
The antihypertensive efficacy and tolerability of a low dose combination of ramipril and felodipine ER in mild to moderate essential hypertension.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:4

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Humans; Male; Middle Aged; Ramipril

1993
Initiation of hypertension treatment with a fixed-dose combination or its monocomponents -- does it really matter?
    International journal of clinical practice, 2006, Volume: 60, Issue:3

    Topics: Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Treatment Outcome

2006
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.
    Circulation, 2007, Apr-17, Volume: 115, Issue:15

    Topics: Adult; Aged; Antihypertensive Agents; Appetite Depressants; Blood Pressure; Body Weight; Cyclobutanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Obesity; Prospective Studies; Ramipril; Treatment Outcome; Verapamil

2007
Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.
    Blood pressure. Supplement, 2008, Volume: 2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008

Other Studies

13 other study(ies) available for felodipine and ramipril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effects of antihypertensive therapy on carotid vascular structure in man.
    Cardiovascular research, 1995, Volume: 30, Issue:1

    Topics: Adult; Aged; Carotid Arteries; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tunica Intima; Ultrasonography

1995
Cardiovascular effects of a low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.
    British journal of pharmacology, 1997, Volume: 121, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Felodipine; Heart Rate; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Mesenteric Arteries; Ramipril; Rats; Rats, Inbred SHR

1997
Influence of dietary salts on the cardiovascular effects of low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.
    British journal of pharmacology, 1998, Volume: 123, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Drug Interactions; Felodipine; Heart Rate; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Insulin; Kidney; Lysine; Magnesium Chloride; Male; Mesenteric Arteries; Muscle Relaxation; Potassium Chloride; Ramipril; Rats; Rats, Inbred SHR; Sodium, Dietary

1998
Felodipine inhibits free-radical production by cytokines and glucose in human smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:6

    Topics: Calcium Channel Blockers; Cells, Cultured; Cytokines; Felodipine; Free Radicals; Glucose; Humans; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ramipril; RNA, Messenger; Superoxides

1998
[Best antihypotensive agents for the treatment of type 2 diabetes. Ramipril, the first choice, in combination with felodipin is a sensible treatment plan].
    Der Internist, 1999, Volume: 40, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Combinations; Felodipine; Humans; Pilot Projects; Prospective Studies; Ramipril

1999
Improvement in midwall myocardial shortening with regression of left ventricular hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:5

    Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Cardiac Output; Echocardiography; Endocardium; Felodipine; Female; Heart; Heart Septum; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Contraction; Ramipril; Ventricular Function, Left

2000
[Dangerous duo: hypertension and pre-diabetes--the underestimated risk].
    MMW Fortschritte der Medizin, 2003, Jan-23, Volume: 145, Issue:3-4

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Combinations; Felodipine; Follow-Up Studies; Humans; Hypertension; Prediabetic State; Ramipril

2003
Development and validation of TLC-densitometric method for simultaneous determination of two binary antihypertensive mixtures containing felodipine in fixed dose combinations.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:2

    Topics: Antihypertensive Agents; Chromatography, Thin Layer; Densitometry; Drug Stability; Felodipine; Limit of Detection; Linear Models; Metoprolol; Ramipril; Reproducibility of Results

2016