felodipine and nimodipine

felodipine has been researched along with nimodipine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's10 (33.33)18.2507
2000's10 (33.33)29.6817
2010's9 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dietel, M; Höllt, V; Kouba, M; Vogt, G1
Knaus, EE; Yiu, S1
Topliss, JG; Yoshida, F1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Sun, H1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Chen, T; Forman, BM; Lin, W; Yu, DD1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Guido, S; Joseph, T1
Hårding, H; Skarphedinsson, J; Thorén, P1
Dong, H; Lu, YQ; Wang, Q; Yang, QQ; Yang, ZC1
Skarphedinsson, JO; Thorén, P; Westling, H1
Dai, ZX; Xu, DZ; Yang, ZC; Yao, MH1
Matesić, D; Mrsić, J; Simonić, A; Vitezić, D; Zupan, G1
Dumitrescu, A; Haga, Y; Sjöquist, PO; Stain-Malmgren, R; Zhang, Y1
Jaroszkiewicz, E; Marciniec, B; Ogrodowczyk, M; Patterson, LH; Taiwo, FA1
Knaus, EE; Yiu, SH1
Camargo, C; Núñez-Vergara, LJ; Ortiz, ME; Squella, JA1
Mielcarek, J; Naskrent, M1
Hammad, MA; Mohamed, AA; Mohamed, AM; Omar, MA1

Reviews

1 review(s) available for felodipine and nimodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

29 other study(ies) available for felodipine and nimodipine

ArticleYear
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine

1992
Synthesis, biological evaluation, calcium channel antagonist activity, and anticonvulsant activity of felodipine coupled to a dihydropyridine-pyridinium salt redox chemical delivery system.
    Journal of medicinal chemistry, 1996, Nov-08, Volume: 39, Issue:23

    Topics: Animals; Anticonvulsants; Biotransformation; Brain; Calcium Channel Blockers; Dihydropyridines; Felodipine; Male; Mice; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Sodium Chloride

1996
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery.
    Bioorganic & medicinal chemistry, 2013, Jul-15, Volume: 21, Issue:14

    Topics: Biological Assay; Drug Discovery; Fluoresceins; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Gene Expression Regulation; Isoxazoles; Molecular Structure; Protein Binding; Receptors, Cytoplasmic and Nuclear

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:4

    Topics: Animals; Blood; Calcium; Clofibrate; Dietary Fats; Diltiazem; Felodipine; Lipids; Male; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Verapamil

1992
Effect of the calcium antagonists felodipine and nimodipine on cortical blood flow in the spontaneously hypertensive rat.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 4

    Topics: Animals; Cerebral Cortex; Cerebrovascular Circulation; Felodipine; Nimodipine; Rats; Rats, Inbred SHR

1990
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Nimodipine; Serotonin Antagonists; Swine; Verapamil

1991
Effect of the calcium antagonists felodipine and nimodipine on cortical blood flow in the spontaneously hypertensive rat.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:4

    Topics: Animals; Blood Pressure; Cerebral Cortex; Felodipine; Homeostasis; Hydrogen; Hypertension; Male; Nimodipine; Rats; Rats, Inbred SHR; Regional Blood Flow

1989
Effects of nimodipine, felodipine, and verapamil on isolated human arteries.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:1

    Topics: Adult; Calcium Chloride; Felodipine; Female; Humans; In Vitro Techniques; Male; Mesenteric Arteries; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nimodipine; Norepinephrine; Renal Artery; Verapamil

1995
Effects of nimodipine, felodipine and amlodipine on electroconvulsive shock-induced amnesia in the rat.
    European journal of pharmacology, 1996, Aug-29, Volume: 310, Issue:2-3

    Topics: Amlodipine; Amnesia; Animals; Calcium Channel Blockers; Electroconvulsive Therapy; Felodipine; Nimodipine; Rats; Rats, Wistar

1996
Effects of calcium blockers on the cytosolic calcium, H2O2 production and elastase release in human neutrophils.
    Pharmacology & toxicology, 1996, Volume: 79, Issue:6

    Topics: Calcium; Calcium Channel Blockers; Cytosol; Felodipine; Humans; Hydrogen Peroxide; Leukocyte Elastase; Neutrophil Activation; Neutrophils; Nimodipine; Verapamil

1996
Free radicals in irradiated drugs: an EPR study.
    Free radical research, 1999, Volume: 31, Issue:3

    Topics: Calcium Channel Blockers; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Felodipine; Free Radicals; Gamma Rays; Nifedipine; Nimodipine; Nitrendipine

1999
Synthesis, calcium channel antagonist activity, and anticonvulsant activity of 3-ethyl 5-methyl 1,4-dihydro-2-[(2-hydroxyethoxy) methyl]-6-methyl-4-(2,3-dichlorophenyl)-3,5-pyridinedicarboxylate coupled to a 1-methyl-1,4-dihydropyridyl-3-carbonyl chemical
    Archiv der Pharmazie, 1999, Volume: 332, Issue:10

    Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Dihydropyridines; Felodipine; Guinea Pigs; Mice; Muscle, Smooth; Nimodipine

1999
Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.
    Pharmaceutical research, 2004, Volume: 21, Issue:3

    Topics: Calcium Channel Blockers; Felodipine; Nifedipine; Nimodipine; Nitrendipine; Superoxides

2004
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 67, Issue:1

    Topics: Calcium Channel Blockers; Dihydropyridines; Electron Spin Resonance Spectroscopy; Felodipine; Gamma Rays; Humans; Hypertension; Models, Molecular; Molecular Conformation; Myocardial Ischemia; Nifedipine; Nimodipine

2007
Spectrofluorimetric and micelle-enhanced spectrofluorimetric methods for determination of Felodipine and Nimodipine in pharmaceutical preparations and human plasma.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Volume: 149

    Topics: Chemistry, Pharmaceutical; Felodipine; Humans; Hydrogen-Ion Concentration; Limit of Detection; Methanol; Micelles; Nimodipine; Polysorbates; Reproducibility of Results; Solvents; Spectrometry, Fluorescence; Temperature; Time Factors

2015