felodipine has been researched along with indomethacin in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.56) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 9 (25.00) | 29.6817 |
| 2010's | 20 (55.56) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Bergström, CA; Hubatsch, I; Johansson, K; Wassvik, CM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Gustafsson, LE; Hedqvist, P; Ohlén, A; Wiklund, CU; Wiklund, NP | 1 |
| Bailey, DG; Bartle, WR; Edgar, B; Hardy, BG; Myers, M | 1 |
| Anderson, A; Morgan, T | 1 |
| Rumondor, AC; Taylor, LS | 1 |
| Alonzo, DE; Gao, Y; Taylor, LS; Zhang, GG; Zhou, D | 1 |
| Abiad, MG; Campanella, OH; Carvajal, MT; Gonzalez, DC; Mert, B | 1 |
| Alonzo, DE; Gao, Y; Mo, H; Taylor, LS; Zhang, GGZ; Zhou, D | 1 |
| Andrews, GP; Brennan, CM; Healy, AM; Holm, R; Jones, DS; Knopp, MM; Kozyra, A; Löbmann, K; Olesen, NE; Paluch, K; Rades, T; Tajber, L; Tian, Y | 1 |
| Alexander, MR; Boissier, C; Iuraş, A; Nicholas, ML; Roberts, CJ; Scurr, DJ | 1 |
| Dell'orco, PC; Floyd, PD; Skrdla, PJ | 1 |
| Abreu-Villela, R; Adler, C; Caraballo, I; Kuentz, M | 1 |
| Alskär, LC; Bergström, CAS; Johannesson, J; Keemink, J; Porter, CJH | 1 |
| Ben Osman, Y; Liavitskaya, T; Vyazovkin, S | 1 |
| Hirakura, Y; Mizoguchi, R; Waraya, H | 1 |
| Brinkmann, J; Luebbert, C; Rest, F; Sadowski, G | 1 |
| Cai, JH; Cui, BJ; Feng, B; Guan, J; Hao, CY; Jin, Y; Li, YW; Qi, XR; Shi, NQ; Wang, D; Zhang, HM; Zhu, HY | 1 |
| Akbaş, EM; Akbaş, N; Gülaboğlu, M; Mammadov, R; Süleyman, B; Süleyman, H | 1 |
1 review(s) available for felodipine and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for felodipine and indomethacin
| Article | Year |
|---|---|
Effect of indomethacin on the pharmacokinetics and pharmacodynamics of felodipine.
Topics: Adult; Blood Pressure; Diuresis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Felodipine; Heart Rate; Hemodynamics; Humans; Indomethacin; Male; Natriuresis; Nitrendipine; Random Allocation; Time Factors; Vasodilator Agents | 1988 |
Interaction of indomethacin with felodipine and enalapril.
Topics: Arthritis, Rheumatoid; Blood Pressure; Drug Interactions; Enalapril; Felodipine; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Osteoarthritis | 1993 |
33 other study(ies) available for felodipine and indomethacin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Poorly soluble marketed drugs display solvation limited solubility.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Principal Component Analysis; Solubility; Tandem Mass Spectrometry; Thermodynamics | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Endothelin modulation of neuroeffector transmission in rat and guinea pig vas deferens.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Triphosphate; Animals; Autonomic Nervous System; Colforsin; Electric Stimulation; Endothelins; Felodipine; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Neuroeffector Junction; Norepinephrine; Rats; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens | 1990 |
Effect of polymer hygroscopicity on the phase behavior of amorphous solid dispersions in the presence of moisture.
Topics: Calorimetry, Differential Scanning; Felodipine; Humidity; Indomethacin; Methylcellulose; Models, Theoretical; Molecular Structure; Pimozide; Polymers; Polyvinyls; Povidone; Pyrrolidines; Quinidine; Spectrophotometry, Infrared; Wettability | 2010 |
Understanding the behavior of amorphous pharmaceutical systems during dissolution.
Topics: Crystallization; Felodipine; Indomethacin; Powder Diffraction; Solubility; Spectrum Analysis, Raman; X-Ray Diffraction | 2010 |
A novel method to measure the glass and melting transitions of pharmaceutical powders.
Topics: Acoustics; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Elastic Modulus; Felodipine; Griseofulvin; Indomethacin; Oscillometry; Polyethylene Glycols; Powder Diffraction; Powders; Rheology; Technology, Pharmaceutical; Transition Temperature; Vibration; X-Ray Diffraction | 2010 |
Dissolution and precipitation behavior of amorphous solid dispersions.
Topics: Calorimetry, Differential Scanning; Chemical Precipitation; Chemistry, Pharmaceutical; Crystallization; Felodipine; Hypromellose Derivatives; Indomethacin; Light; Magnetic Resonance Spectroscopy; Methylcellulose; Microscopy, Polarization; Models, Chemical; Particle Size; Phase Transition; Povidone; Scattering, Radiation; Solubility; Spectrophotometry, Ultraviolet; Surface Properties | 2011 |
Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility.
Topics: Acetaminophen; Calorimetry, Differential Scanning; Celecoxib; Chemistry, Pharmaceutical; Chloramphenicol; Crystallization; Drug Stability; Felodipine; Indomethacin; Polymers; Povidone; Pyrrolidinones; Solubility; Thermodynamics; Vinyl Compounds | 2015 |
Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials.
Topics: Acetaminophen; Chemistry, Pharmaceutical; Crystallization; Felodipine; Indomethacin; Spectrometry, Mass, Secondary Ion; Surface Properties; Time Factors | 2016 |
Practical Estimation of Amorphous Solubility Enhancement Using Thermoanalytical Data: Determination of the Amorphous/Crystalline Solubility Ratio for Pure Indomethacin and Felodipine.
Topics: Chemistry, Pharmaceutical; Crystallization; Felodipine; Indomethacin; Models, Chemical; Solubility; Thermodynamics | 2016 |
Electron microscopy/energy dispersive X-ray spectroscopy of drug distribution in solid dispersions and interpretation by multifractal geometry.
Topics: Amlodipine; Crystallography, X-Ray; Dosage Forms; Drug Carriers; Drug Compounding; Felodipine; Fractals; Glyburide; Indomethacin; Methylcellulose; Microscopy, Electron, Scanning; Pharmaceutical Preparations; Powder Diffraction; Solubility; Spectrometry, X-Ray Emission; Technology, Pharmaceutical | 2018 |
Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations.
Topics: Drug Compounding; Felodipine; Indomethacin; Lipolysis; Microscopy; Solubility; Spectrum Analysis, Raman | 2018 |
Polyvinylpyrrolidone affects thermal stability of drugs in solid dispersions.
Topics: Drug Stability; Felodipine; Indomethacin; Nifedipine; Povidone; Thermogravimetry | 2018 |
Application of Co-Amorphous Technology for Improving the Physicochemical Properties of Amorphous Formulations.
Topics: Crystallization; Drug Compounding; Drug Design; Drug Discovery; Drug Stability; Drug Storage; Felodipine; Hydrogen Bonding; Indomethacin; Polymers; Solubility; Spectroscopy, Near-Infrared; Wettability | 2019 |
Solubility of Pharmaceutical Ingredients in Natural Edible Oils.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cinnarizine; Coconut Oil; Drug Compounding; Drug Delivery Systems; Excipients; Felodipine; Fenofibrate; Griseofulvin; Ibuprofen; Indomethacin; Models, Molecular; Naproxen; Plant Oils; Solubility; Soybean Oil; Spectrum Analysis, Raman; Thermodynamics; Transition Temperature; Triglycerides | 2020 |
"Felodipine-indomethacin" co-amorphous supersaturating drug delivery systems: "Spring-parachute" process, stability, in vivo bioavailability, and underlying molecular mechanisms.
Topics: Analgesics; Antihypertensive Agents; Biological Availability; Crystallization; Drug Combinations; Drug Compounding; Drug Delivery Systems; Drug Interactions; Felodipine; Indomethacin; Solubility | 2021 |
Effect of felodipine on indomethacin-induced gastric ulcers in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Famotidine; Felodipine; Indomethacin; Rats; Rats, Wistar; Stomach Ulcer | 2023 |