felodipine and hydrochlorothiazide

felodipine has been researched along with hydrochlorothiazide in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (9.80)	18.7374
1990's	20 (39.22)	18.2507
2000's	16 (31.37)	29.6817
2010's	10 (19.61)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Leary, WP; Maharaj, B	1
Flygt, G; Stanek, B; Weissel, M	1
Binner, L; Gabrielsen, F; Hombach, V; Koenig, W; Rosenthal, J; Sund, M	1
Binner, L; Hehr, R; Hombach, V; Koenig, W; Rosenthal, J; Sund, M	1
Lopez, LM; Yedinak, KC	1
Ibsen, H; Westberg, B	1
Binner, L; Ernst, E; Hehr, R; Hombach, V; Koenig, W; Rosenthal, J; Sund, M	1
Bengtsson, C; Bengtsson, L; Lapidus, L; Lundgren, H	1
Borgmästars, H; Forsén, B; Hellebø, R; Ibsen, H; Nielsen, E; Nielsen, HM; Steiness, E; Tuomilehto, J; Walle, PO; Winkel, O	1
Hedner, T	1
Groom, P; Peers, E; Richardson, PD; Simpson, RJ; Singh, B; Ward, DE	1
Carle, WK; Latta, D; Lees, CT; Lough, JR; Peers, EM; Pender, J; Richardson, PD; Ross, JR; Sefton, S	1
Flygt, G; Krönig, B	1
Aulehner, R; Dobrindt, R; Lydtin, H; Trenkwalder, P	1
Dunlay, MC; Goldberg, AI; Sweet, CS	1
Hasselgren, B; Johansson, P	1
Landahl, S	1
Asmar, RG; Benetos, A; Chaouche-Teyara, K; Raveau-Landon, CM; Safar, ME	1
Carruthers, SG; Vint-Reed, C	1
Bengtsson, C; Lapidus, L	1
Aulehner, R; Lydtin, H; Plaschke, M; Trenkwalder, P	1
Kolloch, RE; Rahn, KH	1
McClennen, W; Wilson, T	1
Airaksinen, KE; Huikuri, HV; Sellin, L; Ylitalo, A	1
Klein, G	1
Trenkwalder, P	1
Eicke, C; Grässel, E; Lehrl, S	1
Aurup, P; Goldberg, A; Oparil, S; Snavely, D	1
Anderson, A; Morgan, TO	1
Kjeldsen, SE; Os, I; Westheim, AS	1
Li, W; Liu, G; Liu, L; Zanchetti, A; Zhang, X; Zhang, Y	1
Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T	1
Plachý, M; Soucek, M	1
Chen, YY; Liu, HL; Shen, FR; Sun, NL; Tao, J; Wu, HY; Xiang, XP; Yu, ZQ; Zhang, FC; Zhang, L; Zhang, WZ; Zhao, JA	1
Liu, L; Zanchetti, A; Zhang, X; Zhang, Y	1
Alexander, MR; Gellert, PR; Hook, AL; Roberts, CJ; Scoutaris, N; Scurr, DJ	1
Liu, L; Tang, X; Wang, Y; Zanchetti, A; Zhang, X; Zhang, Y	1

Reviews

2 review(s) available for felodipine and hydrochlorothiazide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Felodipine: a new dihydropyridine calcium-channel antagonist. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:11 Topics: Angina Pectoris; Animals; Blood Pressure; Double-Blind Method; Felodipine; Heart Failure; Humans; Hydrochlorothiazide; Hypertension	1991

Trials

35 trial(s) available for felodipine and hydrochlorothiazide

Article	Year
Comparison of felodipine and hydrochlorothiazide for the treatment of mild to moderate hypertension in black Africans. Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 4 Topics: Adult; Africa; Black People; Blood Pressure; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Randomized Controlled Trials as Topic	1990
Felodipine is more effective than hydrochlorothiazide when added to a beta-blocker in treating elderly hypertensive patients. Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 4 Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Body Weight; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic	1990
Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension. Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3 Topics: Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Delayed-Action Preparations; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pressoreceptors; Renin; Renin-Angiotensin System	1991
Comparison of once daily felodipine 10 mg ER and hydrochlorothiazide 25 mg in the treatment of mild to moderate hypertension. European journal of clinical pharmacology, 1991, Volume: 41, Issue:3 Topics: Administration, Oral; Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged	1991
Felodipine: a new dihydropyridine calcium-channel antagonist. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:11 Topics: Angina Pectoris; Animals; Blood Pressure; Double-Blind Method; Felodipine; Heart Failure; Humans; Hydrochlorothiazide; Hypertension	1991
The efficacy and tolerability of long-term felodipine treatment in hypertension. The Scandinavian Multicenter Group. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Ankle; Blood Pressure; Body Weight; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Felodipine; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Time Factors	1990
Effects of felodipine ER and hydrochlorothiazide on blood rheology in essential hypertension--a randomized, double-blind, crossover study. Journal of internal medicine, 1991, Volume: 229, Issue:6 Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Rheology	1991
Antihypertensive drugs and glucose metabolism: comparison between a diuretic, a beta-blocker and felodipine, a new calcium antagonist in subjects with arterial hypertension and diabetes. Journal of internal medicine, 1990, Volume: 228, Issue:6 Topics: Aged; Blood Glucose; Diabetes Mellitus; Double-Blind Method; Felodipine; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged	1990
Felodipine versus hydrochlorothiazide as an addition to a beta-blocker in the treatment of hypertension. Drugs, 1987, Volume: 34 Suppl 3 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine	1987
Clinical evaluation of felodipine in hypertensive patients previously treated with a triple drug regimen. Drugs, 1987, Volume: 34 Suppl 3 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Nitrendipine	1987
A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension. European journal of clinical pharmacology, 1988, Volume: 34, Issue:1 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Headache; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Random Allocation; Time Factors	1988
A comparison of felodipine and propranolol as additions to hydrochlorothiazide in the treatment of hypertension. European journal of clinical pharmacology, 1988, Volume: 34, Issue:2 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine; Propranolol; Random Allocation	1988
Felodipine versus Moduretic. A double-blind parallel-group multicentre study. Drugs, 1987, Volume: 34 Suppl 3 Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrendipine; Random Allocation	1987
Antihypertensive treatment with felodipine but not with a diuretic reduces episodes of myocardial ischaemia in elderly patients with hypertension. European heart journal, 1994, Volume: 15, Issue:12 Topics: Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Myocardial Ischemia; Triamterene	1994
Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension. The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Asthenia; Atenolol; Biphenyl Compounds; Cough; Dizziness; Double-Blind Method; Fatigue; Felodipine; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Placebos; Respiratory Tract Infections; Safety; Tetrazoles	1995
Natriuretic and diuretic effects of felodipine and hydrochlorothiazide after single and repeated doses. European journal of clinical pharmacology, 1995, Volume: 47, Issue:5 Topics: Adult; Blood Pressure; Body Weight; Cross-Over Studies; Diuresis; Double-Blind Method; Felodipine; Heart Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis	1995
[Good quality of life of older patients with hypertension. Equally good effect of felodipine and hydrochlorothiazide]. Lakartidningen, 1995, Apr-26, Volume: 92, Issue:17 Topics: Aged; Double-Blind Method; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Quality of Life	1995
Comparison of effects of felodipine versus hydrochlorothiazide on arterial diameter and pulse-wave velocity in essential hypertension. The American journal of cardiology, 1993, Oct-01, Volume: 72, Issue:11 Topics: Adult; Aged; Brachial Artery; Carotid Arteries; Double-Blind Method; Felodipine; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulsatile Flow; Vascular Resistance	1993
Antihypertensive effect and tolerability of felodipine extended release (ER) tablets in comparison with felodipine plain tablets (PT) and placebo in hypertensives on a diuretic. Canadian Study Group. Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:5 Topics: Adult; Aged; Blood Pressure; Body Weight; Canada; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos	1993
Antihypertensive drugs and glucose metabolism: a comparison between a diuretic and felodipine, a new calcium antagonist, when added to a beta-blocker in non-diabetic hypertensive women. Scottish medical journal, 1994, Volume: 39, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Felodipine; Female; Glucose; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Middle Aged; Sodium Chloride Symporter Inhibitors; Treatment Outcome	1994
Felodipine or hydrochlorothiazide/triamterene for treatment of hypertension in the elderly: effects on blood pressure, hypertensive heart disease, metabolic and hormonal parameters. Blood pressure, 1996, Volume: 5, Issue:3 Topics: Aged; Aged, 80 and over; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Felodipine; Female; Heart Diseases; Heart Rate; Hormones; Humans; Hydrochlorothiazide; Hypertension; Male; Triamterene	1996
[The Hypertension Optimal Treatment (HOT) study: results of 12-month therapy related to age]. Deutsche medizinische Wochenschrift (1946), 1998, Jan-02, Volume: 123, Issue:1-2 Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Diastole; Diuretics; Felodipine; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Sodium Chloride Symporter Inhibitors; Time Factors	1998
Felodipine extended release versus conventional diuretic therapy for the treatment of systolic hypertension in elderly patients. The National Trial Group. Clinical and investigative medicine. Medecine clinique et experimentale, 1998, Volume: 21, Issue:3 Topics: Aged; Aged, 80 and over; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Postmenopause; Prospective Studies; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Systole; Triamterene; Vasodilator Agents	1998
Effects of combination antihypertensive therapy on baroreflex sensitivity and heart rate variability in systemic hypertension. The American journal of cardiology, 1999, Mar-15, Volume: 83, Issue:6 Topics: Aged; Antihypertensive Agents; Baroreflex; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Echocardiography, Doppler, Color; Electrocardiography, Ambulatory; Enalapril; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Phenylephrine	1999
Combination therapy with felodipine and metoprolol compared with captopril and hydrochlorothiazide. German MC Study Group. Blood pressure, 1998, Volume: 7, Issue:5-6 Topics: Antihypertensive Agents; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged	1998
[Cognition disorders and dementia--new end-organ damage in hypertension]. Deutsche medizinische Wochenschrift (1946), 2000, Nov-10, Volume: 125, Issue:45 Topics: Aged; Amiloride; Cognition Disorders; Dementia; Double-Blind Method; Felodipine; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Neuropsychological Tests	2000
[Effectiveness of felodipine in hypertensive patients with mild cerebral cognition disorders in a randomized double-blind study]. Deutsche medizinische Wochenschrift (1946), 2000, Nov-10, Volume: 125, Issue:45 Topics: Aged; Amiloride; Blood Viscosity; Brain; Cognition Disorders; Dementia; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Microcirculation; Middle Aged; Neuropsychological Tests; Treatment Outcome	2000
Efficacy and safety of losartan/hydrochlorothiazide in patients with severe hypertension. The American journal of cardiology, 2001, Mar-15, Volume: 87, Issue:6 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Treatment Outcome	2001
Different drug classes have variable effects on blood pressure depending on the time of day. American journal of hypertension, 2003, Volume: 16, Issue:1 Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Cross-Over Studies; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Perindopril	2003
The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients. Journal of hypertension, 2005, Volume: 23, Issue:12 Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; China; Diuretics; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Stroke	2005
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study. Circulation, 2007, Apr-17, Volume: 115, Issue:15 Topics: Adult; Aged; Antihypertensive Agents; Appetite Depressants; Blood Pressure; Body Weight; Cyclobutanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Obesity; Prospective Studies; Ramipril; Treatment Outcome; Verapamil	2007
[The FEVER (Felodipine EVEnt Reduction) trial; a randomised, double-blind, placebo-controlled trial in Chinese hypertensive patients]. Vnitrni lekarstvi, 2007, Volume: 53, Issue:1 Topics: Aged; Calcium Channel Blockers; China; Diuretics; Double-Blind Method; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Stroke	2007
[Efficacy, safety and tolerance of Felodipine controlled release tablets and Felodipine controlled release tablets associated combination therapy in the treatment of mild to moderate essential hypertension in China]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2007, Dec-18, Volume: 39, Issue:6 Topics: Adult; Aged; Antihypertensive Agents; China; Delayed-Action Preparations; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Metoprolol; Middle Aged; Patient Compliance	2007
Is a systolic blood pressure target <140 mmHg indicated in all hypertensives? Subgroup analyses of findings from the randomized FEVER trial. European heart journal, 2011, Volume: 32, Issue:12 Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Treatment Outcome	2011
Higher cardiovascular risk and impaired benefit of antihypertensive treatment in hypertensive patients requiring additional drugs on top of randomized therapy: is adding drugs always beneficial? Journal of hypertension, 2012, Volume: 30, Issue:11 Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; China; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Treatment Outcome	2012

Other Studies

15 other study(ies) available for felodipine and hydrochlorothiazide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
More heat to support aggressive blood pressure lowering: the FEVER study. Journal of hypertension, 2005, Volume: 23, Issue:12 Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Felodipine; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic	2005
ToF-SIMS analysis of chemical heterogenities in inkjet micro-array printed drug/polymer formulations. Journal of materials science. Materials in medicine, 2012, Volume: 23, Issue:2 Topics: Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Design; Felodipine; Hydrochlorothiazide; Ions; Lactic Acid; Mass Spectrometry; Microarray Analysis; Models, Chemical; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyls; Printing; Pyrrolidinones; Sodium Chloride; Spectrometry, Mass, Secondary Ion; Surface Properties	2012