felodipine and cyclosporine

felodipine has been researched along with cyclosporine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (48.65)18.2507
2000's12 (32.43)29.6817
2010's6 (16.22)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Eiskjaer, H; Pedersen, EB; Skovbon, H; Sørensen, SS; Thomsen, K2
Dieperink, H; Hansen, HV; Kemp, E; Kemp, M; Leyssac, PP; Starklint, H1
Appel, GB; Cohen, DJ; Teng, SN1
Cambar, J; L'Azou, B; Lakhdar, B1
Blohmé, I; Haljamäe, U; Herlitz, H; Nordén, G; Nyberg, G1
Huttunen, KR; Knuuttila, ML; Pernu, HE; Tiilikainen, AS1
Kornerup, HJ; Madsen, JK; Pedersen, EB1
Jensen, JD; Jensen, LW; Madsen, JK; Pedersen, EB1
Madsen, JK; Pedersen, EB; Sørensen, SS; Zachariae, H1
Ambrosi, P; Bertault-Péres, P; Bertucci, B; Métras, D1
Cassada, D; Goldman, M; Grindstaff, A; Pan, Y; Taylor, J1
Yeleswaram, K1
Hansen, HE; Madsen, JK; Pedersen, EB; Sørensen, SS1
Akkaya, V; Ark, E; Ecder, T; Sever, MS; Türk, S; Türkmen, A; Yildiz, A1
Chen, H; Daloze, P; Dumont, L; Lapointe, N; Qi, S; Xu, D1
Chatterjee, K; De Marco, T; Globits, S; Higgins, CB; Klinski, C; Parmley, WW; Sakuma, H; Schwitter, J1
Hoffmann, R; Krisp, A1
Benet, LZ; Cummins, CL; Jacobsen, W1
Eggerath, J; English, H; Leichter, JW1
Ahya, VN1

Reviews

1 review(s) available for felodipine and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for felodipine and cyclosporine

ArticleYear
Effect of felodipine on renal haemodynamics and tubular sodium handling in cyclosporin-treated renal transplant recipients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1992, Volume: 7, Issue:1

    Topics: Adult; Cyclosporine; Diuresis; Felodipine; Glomerular Filtration Rate; Humans; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Natriuresis; Renal Circulation

1992
Interaction between cyclosporine and felodipine in renal transplant recipients.
    Kidney international. Supplement, 1992, Volume: 36

    Topics: Adult; Blood Pressure; Cyclosporine; Drug Interactions; Felodipine; Glomerular Filtration Rate; Humans; Kidney; Kidney Transplantation; Lithium; Male; Middle Aged; Renal Circulation

1992
Effect of felodipine on renal haemodynamics and tubular sodium handling after single-dose cyclosporin infusion in renal transplant recipients treated with azathioprine and prednisolone.
    Scandinavian journal of clinical and laboratory investigation, 1995, Volume: 55, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Aged; Azathioprine; Cross-Over Studies; Cyclosporine; Double-Blind Method; Felodipine; Female; Hemodynamics; Hormones; Humans; Immunosuppressive Agents; Infusions, Intravenous; Kidney Function Tests; Kidney Transplantation; Kidney Tubules; Lithium; Male; Middle Aged; Prednisolone; Renal Circulation; Sodium; Vasodilator Agents

1995
Pharmacokinetic interaction between cyclosporine and the dihydropyridine calcium antagonist felodipine.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:3

    Topics: Adult; Area Under Curve; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Cyclosporine; Double-Blind Method; Drug Interactions; Felodipine; Humans; Immunosuppressive Agents; Male

1996
Improvement in renal function by felodipine during cyclosporine treatment in acute and short-term studies.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Cyclosporine; Double-Blind Method; Felodipine; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Function Tests; Kidney Transplantation; Kidney Tubules; Lithium; Male; Renal Circulation

1996
The effect of felodipine on renal function and blood pressure in cyclosporin-treated renal transplant recipients during the first three months after transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cyclosporine; Double-Blind Method; Felodipine; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Middle Aged; Postoperative Care; Renal Circulation; Vasodilator Agents

1998
Interaction between cyclosporine A and verapamil, felodipine, and isradipine.
    Nephron, 1999, Volume: 81, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Felodipine; Female; Humans; Immunosuppressive Agents; Isradipine; Kidney Transplantation; Male; Verapamil

1999
Influence of felodipine on left ventricular hypertrophy and systolic function in orthotopic heart transplant recipients: possible interaction with cyclosporine medication.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:10

    Topics: Analysis of Variance; Antihypertensive Agents; Cyclosporine; Diuretics; Drug Interactions; Felodipine; Female; Heart Transplantation; Heart Ventricles; Humans; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Linear Models; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Systole

1999

Other Studies

28 other study(ies) available for felodipine and cyclosporine

ArticleYear
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antagonist capacity of felodipine on cyclosporin A nephrotoxicity in the rat.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1992, Volume: 7, Issue:11

    Topics: Absorption; Analysis of Variance; Animals; Cyclosporine; Felodipine; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley

1992
Grapefruit juice interactions with drugs.
    The Medical letter on drugs and therapeutics, 1995, Aug-18, Volume: 37, Issue:955

    Topics: Beverages; Caffeine; Citrus; Cyclosporine; Estrogens; Felodipine; Food-Drug Interactions; Humans; Midazolam; Nifedipine; Terfenadine

1995
Influence of oral felodipine on serum cyclosporine concentrations.
    Clinical transplantation, 1994, Volume: 8, Issue:6

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Cyclosporine; Drug Interactions; Felodipine; Humans; Hypertension, Renal; Immunosuppression Therapy; Kidney Transplantation; Postoperative Complications

1994
Use of two in vitro glomerular models to study the renal vasoreactivity of cyclosporine.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Felodipine; Glomerular Mesangium; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Kinetics; Nifedipine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Verapamil

1994
Early renal graft function in recipients treated with the calcium channel blocker felodipine.
    Scandinavian journal of urology and nephrology, 1994, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Cadaver; Creatinine; Cyclosporine; Felodipine; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Premedication; Regional Blood Flow; Renal Dialysis; Retrospective Studies

1994
Drug-induced gingival overgrowth and class II major histocompatibility antigens.
    Transplantation, 1994, Jun-27, Volume: 57, Issue:12

    Topics: Adult; Amlodipine; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Felodipine; Female; Gingiva; Gingival Diseases; Histocompatibility Testing; HLA-DR Antigens; Humans; Kidney Transplantation; Male; Nifedipine; Retrospective Studies; Risk Factors

1994
Felodipine in hypertensive heart transplant recipients.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1996, Volume: 15, Issue:5

    Topics: Blood Pressure; Calcium Channel Blockers; Creatinine; Cyclosporine; Felodipine; Follow-Up Studies; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Middle Aged; Prospective Studies

1996
Bilateral reduction mammoplasty in a patient treated with calcium channel blocker and cyclosporine after renal transplant: a case report.
    Transplantation, 1997, Apr-15, Volume: 63, Issue:7

    Topics: Adult; Breast Diseases; Cadaver; Calcium Channel Blockers; Cyclosporine; Felodipine; Female; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Mammaplasty; Prolactin

1997
Comment on "Pharmacokinetic interaction between cyclosporine and the dihydropyridine calcium antagonist felodipine".
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Felodipine; Humans; Immunosuppressive Agents; Intestinal Mucosa; Intestines; Liver

1997
Immunomodulating effects of second-generation calcium channel blockers on experimental heart transplantation.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:3

    Topics: Adjuvants, Immunologic; Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Therapy, Combination; Felodipine; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Mibefradil; Rats; Rats, Inbred Lew; Tetrahydronaphthalenes; Time Factors

1999
[Letter concerning the article by E.C.Bornhövd, E.Schuller, T.Bieber, A.Wollenberg: "Immunosuppressive macrolides and their use in dermatology". Der Hautarzt (2000) 51:646-654].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2001, Volume: 52, Issue:3

    Topics: Beverages; Calcium Channel Blockers; Citrus; Cyclosporine; Digestive System; Drug Interactions; Felodipine; Humans; Immunosuppressive Agents; Liver; Skin Diseases; Tacrolimus; Xenobiotics

2001
Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Felodipine; Humans; Immunosuppressive Agents; Intestinal Mucosa; Intestines; Isoquinolines; Mass Spectrometry; Mixed Function Oxygenases; Tetrahydroisoquinolines; Transfection

2002
Drug-associated gingival enlargement: case report and review of aetiology, management and evidence-based outcomes of treatment.
    Journal of the New Zealand Society of Periodontology, 2005, Issue:88

    Topics: Adult; Anti-Infective Agents; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Decision Trees; Dental Plaque; Felodipine; Gingival Hyperplasia; Gingivectomy; Humans; Immunosuppressive Agents; Male; Metronidazole

2005
Pharmacological approaches to preserving renal function early after lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2020, Volume: 39, Issue:6

    Topics: Cyclosporine; Felodipine; Humans; Lung Transplantation

2020