felbamate and carbamazepine

felbamate has been researched along with carbamazepine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.37)18.7374
1990's32 (43.84)18.2507
2000's24 (32.88)29.6817
2010's14 (19.18)24.3611
2020's2 (2.74)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Bialer, M; Hen, N; Yagen, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bertram, E; Cereghino, JJ; Dreifuss, FE; Drury, I; Graves, NM; Jacobs, MP; Leppik, IE; Pledger, GW; Santilli, N; Tsay, JY1
Graves, NM; Miller, SA; Remmel, RP1
Graves, NM; Holmes, GB; Leppik, IE1
Banfield, CR; Colucci, RD; Hulsman, JA; Lin, CC; Meehan, JW; Mojaverian, P; Nezamis, J; Radwanski, E; Reidenberg, P; Rentmeester, TW1
Patsalos, PN; Sander, JW1
Pledger, GW; Sahlroot, JT1
Kucharczyk, N; Romanyshyn, LA; Shumaker, RC; Sofia, RD; Ward, D; Wichmann, JK1
Graves, NM; Leppik, IE1
Graves, NM; Leppik, IE; Remmel, RP; Wagner, ML1
Bialer, M1
Carchman, RA; Carter, WH; Gennings, C; Sofia, RD; Swinyard, EA1
Perucca, E1
Pellock, JM1
Gaily, E; Iivanainen, M1
Bernardi, G; Calabresi, P; Mercuri, NB; Pisani, A; Siniscalchi, A; Stefani, A1
Adami, M; Bertorelli, R; Ferri, N; Ongini, E1
Perucca, E; Pisani, F; Spina, E1
Lee, BI1
Gram, L1
Grippo, J1
Cox, S; Dusci, LJ; Kelley, MT; Walson, PD1
Brodie, MJ; Wilson, EA1
Chapman, DP; Giles, WH1
Banfield, CR; Glue, P; Levy, RH; Mather, GG; Perhach, JL; Racha, JK1
Miller, MB; Morkunas, AR1
Bazil, CW; Pedley, TA1
Bernardi, G; Spadoni, F; Stefani, A1
Berlinghieri, MC; David, E; De Sarro, GB; Dominijanni, A; Elia, M; Gulletta, E; Musumeci, SA1
Anderson, GD1
Bourgeois, BF1
Bassetti, MA; Marciani, MG; Mattia, D; Placidi, F; Romigi, A; Spanedda, F1
White, HS1
Albani, F; Baruzzi, AA; Contin, M; Riva, R1
Vajda, FJ1
Foletti, GB1
Bachański, M; Jóźwiak, S; Karkowska, B; Kmieć, T; Kuczyński, D1
French, JA1
Sirven, JI1
Rekling, JC1
Boyer, S; Egnell, AC; Houston, B1
Bergin, AM; Connolly, M1
Johannessen, SI; Perucca, E1
Fedrowitz, M; Löscher, W; Potschka, H1
Helmers, SL; LaRoche, SM1
Czuczwar, SJ; Luszczki, JJ1
Pucci, V; Raggi, MA1
Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N1
Green, AC; Harrison, PK; Sheridan, RD; Tattersall, JE1
Albani, F; Balboni, M; Baruzzi, A; Callegati, E; Candela, C; Contin, M; Riva, R1
Johannessen, SI; Tomson, T1
Matsuura, M1
Dannhardt, G; Kiefer, W1
Czuczwar, SJ; Danysz, W; Luszczki, JJ1
Hwang, H; Kim, KJ1
Albani, F; Baruzzi, A; Candela, C; Contin, M; Mohamed, S; Riva, R1
Garraghty, PE; Orczyk, JJ1
Agrawal, M; Dhurandhar, Y; Panda, SP1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1

Reviews

32 review(s) available for felbamate and carbamazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
    Drug safety, 1994, Volume: 11, Issue:1

    Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

1994
Advances in pharmacotherapy: recent developments in the treatment of epilepsy.
    Journal of clinical pharmacy and therapeutics, 1993, Volume: 18, Issue:4

    Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1993
Comparative pharmacokinetics of the newer antiepileptic drugs.
    Clinical pharmacokinetics, 1993, Volume: 24, Issue:6

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Felbamate; Flunarizine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1993
Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin

1996
Utilization of new antiepileptic drugs in children.
    Epilepsia, 1996, Volume: 37 Suppl 1

    Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1996
[Current anti-epilepsy drugs].
    Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:8

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1995
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
    Clinical pharmacokinetics, 1996, Volume: 31, Issue:3

    Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid

1996
New antiepileptic drugs. II. Clinical use.
    Journal of Korean medical science, 1996, Volume: 11, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Felbamate; Forecasting; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide

1996
Pharmacokinetics of new antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Cyclohexanecarboxylic Acids; Enzyme Induction; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1996
[Treatment of the epilepsy: new drugs].
    Revista de neurologia, 1996, Volume: 24, Issue:135

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide

1996
New antiepileptic drugs.
    Bailliere's clinical neurology, 1996, Volume: 5, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1996
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
    Southern medical journal, 1997, Volume: 90, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin

1997
Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation.
    Clinical pharmacokinetics, 1997, Volume: 33, Issue:3

    Topics: Anticonvulsants; Area Under Curve; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Epilepsy; Felbamate; Humans; In Vitro Techniques; Isoenzymes; Neuroprotective Agents; Phenylcarbamates; Phenytoin; Propylene Glycols; Valproic Acid

1997
Anticonvulsant hypersensitivity syndrome.
    Critical care clinics, 1997, Volume: 13, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Syndrome

1997
Advances in the medical treatment of epilepsy.
    Annual review of medicine, 1998, Volume: 49

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin

1998
Voltage-activated calcium channels: targets of antiepileptic drug therapy?
    Epilepsia, 1997, Volume: 38, Issue:9

    Topics: Animals; Anticonvulsants; Calcium Channels; Carbamazepine; Drug Design; Epilepsy; Felbamate; Humans; Lamotrigine; Mice; Neuroprotective Agents; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Rats; Triazines

1997
A mechanistic approach to antiepileptic drug interactions.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

1998
New antiepileptic drugs.
    Archives of neurology, 1998, Volume: 55, Issue:9

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Vigabatrin

1998
Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs.
    Epilepsia, 1999, Volume: 40 Suppl 5

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsies, Partial; Felbamate; Fructose; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Receptors, GABA; Sodium Channels; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

1999
New antiepileptic drugs.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2000
The role of new antiepileptic drugs.
    The American journal of managed care, 2001, Volume: 7, Issue:7 Suppl

    Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Felbamate; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Polypharmacy; Propylene Glycols; Randomized Controlled Trials as Topic; Treatment Outcome; Triazines; United States

2001
Antiepileptic drug therapy for adults: when to initiate and how to choose.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:12

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Recurrence; Risk Factors; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2002
New antiepileptic drug therapies.
    Neurologic clinics, 2002, Volume: 20, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2002
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
    Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5 Suppl 1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2003
The new antiepileptic drugs: scientific review.
    JAMA, 2004, Feb-04, Volume: 291, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide

2004
Analysis of antiepileptic drugs in biological fluids by means of electrokinetic chromatography.
    Electrophoresis, 2005, Volume: 26, Issue:4-5

    Topics: Acetazolamide; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Felbamate; Humans; Hydantoins; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Succinimides; Triazines; Valproic Acid; Vigabatrin; Zonisamide

2005
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:11

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2006
[Newer antiepileptic drugs].
    No to shinkei = Brain and nerve, 2007, Volume: 59, Issue:2

    Topics: Amines; Animals; Anti-Anxiety Agents; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drug Interactions; Epilepsy; Felbamate; Fructose; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Neuroprotective Agents; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Sodium Channel Blockers; Topiramate; Triazines; Zonisamide

2007
[New antiepileptics in development].
    Pharmazie in unserer Zeit, 2007, Volume: 36, Issue:4

    Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Felbamate; Humans; Levetiracetam; Phenylcarbamates; Piracetam; Propylene Glycols; Valproic Acid

2007
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
    Mitochondrion, 2022, Volume: 66

    Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid

2022
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022

Trials

7 trial(s) available for felbamate and carbamazepine

ArticleYear
Felbamate for partial seizures: results of a controlled clinical trial.
    Neurology, 1991, Volume: 41, Issue:11

    Topics: Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarbamates; Phenytoin; Propylene Glycols

1991
Compliant populations: variability in serum concentrations.
    Epilepsy research. Supplement, 1988, Volume: 1

    Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Felbamate; Female; gamma-Aminobutyric Acid; Humans; Male; Patient Compliance; Phenylcarbamates; Phenytoin; Propylene Glycols; Random Allocation

1988
Effects of felbamate on the pharmacokinetics of the monohydroxy and dihydroxy metabolites of oxcarbazepine.
    Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cross-Over Studies; Double-Blind Method; Drug Interactions; Felbamate; Humans; Male; Oxcarbazepine; Phenylcarbamates; Propylene Glycols

1995
Dosage adjustments in response to monitored plasma concentrations: can unblinded staff adhere to objective criteria?
    Journal of biopharmaceutical statistics, 1994, Volume: 4, Issue:1

    Topics: Attitude of Health Personnel; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Epilepsy; Felbamate; Humans; Monitoring, Physiologic; Multicenter Studies as Topic; Observer Variation; Phenylcarbamates; Phenytoin; Placebos; Propylene Glycols; Randomized Controlled Trials as Topic; Retrospective Studies

1994
Effect of felbamate on carbamazepine and its major metabolites.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarbamates; Phenytoin; Propylene Glycols

1993
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
    Therapeutic drug monitoring, 1999, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid

1999
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 7

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin

2000

Other Studies

34 other study(ies) available for felbamate and carbamazepine

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Syntheses and evaluation of anticonvulsant activity of novel branched alkyl carbamates.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Animals; Anticonvulsants; Carbamates; Male; Mice; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Structure-Activity Relationship

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Simultaneous assay of felbamate plus carbamazepine, phenytoin, and their metabolites by liquid chromatography with mobile phase optimization.
    Therapeutic drug monitoring, 1990, Volume: 12, Issue:1

    Topics: Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenylcarbamates; Phenytoin; Propylene Glycols

1990
Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by high-performance liquid chromatography.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Quality Control; Regression Analysis; Spectrophotometry, Ultraviolet

1994
Analysis of anticonvulsant and neurotoxic responses to combination therapy with carbamazepine, felbamate and phenytoin by response-surface modeling.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:7

    Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Felbamate; Male; Mice; Phenylcarbamates; Phenytoin; Postural Balance; Propylene Glycols; Regression Analysis

1995
A field potential analysis on the effects of lamotrigine, GP 47779, and felbamate in neocortical slices.
    Neurology, 1996, Volume: 47, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Evoked Potentials; Felbamate; Lamotrigine; Male; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar; Triazines

1996
Effects of four antiepileptic drugs on sleep and waking in the rat under both light and dark phases.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:3

    Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Felbamate; Lamotrigine; Male; Phenylcarbamates; Photic Stimulation; Propylene Glycols; Rats; Rats, Sprague-Dawley; Sleep; Triazines

1996
Population pharmacokinetics of felbamate in children.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Felbamate; Humans; Infant; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Seizures; Valproic Acid

1997
Does antiepileptic therapy affect immune response?
    Journal of chemotherapy (Florence, Italy), 1998, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid

1998
Changes of the EEG paroxysmal pattern during felbamate therapy in Lennox-Gastaut syndrome: a case report.
    The International journal of neuroscience, 1998, Volume: 95, Issue:3-4

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Felbamate; Female; Humans; Phenobarbital; Phenylcarbamates; Propylene Glycols; Syndrome; Valproic Acid

1998
[Clinical utilization of new anti-epileptic agents].
    Revue medicale de la Suisse romande, 2000, Volume: 120, Issue:9

    Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Visual Fields

2000
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid

2003
In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3

    Topics: Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Felbamate; Humans; In Vitro Techniques; Meta-Analysis as Topic; Microsomes, Liver; Phenylcarbamates; Propylene Glycols

2003
Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats.
    Epilepsia, 2003, Volume: 44, Issue:12

    Topics: Amygdala; Animals; Anticonvulsants; Biological Availability; Blood-Brain Barrier; Carbamazepine; Cerebral Cortex; Drug Resistance, Multiple; Electroencephalography; Endothelium, Vascular; Epilepsy; Felbamate; Female; Kindling, Neurologic; Lamotrigine; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phenylcarbamates; Propylene Glycols; Rats; Rats, Mutant Strains; Rats, Wistar; Triazines

2003
Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis.
    Epilepsia, 2004, Volume: 45, Issue:8

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Electroshock; Epilepsy; Felbamate; Fructose; Humans; Lamotrigine; Lethal Dose 50; Male; Mice; Neurotoxicity Syndromes; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Seizures; Topiramate; Triazines

2004
Pharmacodynamic and pharmacokinetic interaction studies of loreclezole with felbamate, lamotrigine, topiramate, and oxcarbazepine in the mouse maximal electroshock seizure model.
    Epilepsia, 2005, Volume: 46, Issue:3

    Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Electroshock; Felbamate; Fructose; Kindling, Neurologic; Lamotrigine; Male; Mice; Motor Activity; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Seizures; Topiramate; Triazines; Triazoles

2005
Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus.
    European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3

    Topics: Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Chlormethiazole; Clozapine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Levetiracetam; Male; Phenylcarbamates; Phenylenediamines; Piracetam; Propylene Glycols; Soman; Topiramate

2005
Simultaneous liquid chromatographic determination of lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in plasma of patients with epilepsy.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Dec-15, Volume: 828, Issue:1-2

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dibenzazepines; Drug Monitoring; Epilepsy; Felbamate; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Spectrophotometry, Ultraviolet; Triazines

2005
Interactions of MRZ 2/576 with felbamate, lamotrigine, oxcarbazepine and topiramate in the mouse maximal electroshock-induced seizure model.
    Pharmacology, 2008, Volume: 81, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Felbamate; Fructose; Injections, Intraperitoneal; Lamotrigine; Male; Mice; Oxcarbazepine; Phenylcarbamates; Phthalazines; Propylene Glycols; Receptors, N-Methyl-D-Aspartate; Seizures; Topiramate; Triazines

2008
New antiepileptic drugs in pediatric epilepsy.
    Brain & development, 2008, Volume: 30, Issue:9

    Topics: Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Pediatrics; Phenylcarbamates; Piracetam; Practice Guidelines as Topic; Propylene Glycols; Topiramate; Triazines; Vigabatrin

2008
Simultaneous HPLC-UV analysis of rufinamide, zonisamide, lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in deproteinized plasma of patients with epilepsy.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Feb-01, Volume: 878, Issue:3-4

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Felbamate; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Triazoles; Ultraviolet Rays; Zonisamide

2010
The effects of felbamate on appetitive and aversive instrumental learning in adult rats.
    Epilepsy & behavior : E&B, 2018, Volume: 78

    Topics: Animals; Anticonvulsants; Appetitive Behavior; Avoidance Learning; Carbamazepine; Cognition; Conditioning, Operant; Felbamate; Female; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Sprague-Dawley; Valproic Acid

2018