Compounds > febuxostat
Page last updated: 2024-09-04

febuxostat and zileuton

febuxostat has been researched along with zileuton in 3 studies

Compound Research Comparison

Studies
(febuxostat)		Trials
(febuxostat)		Recent Studies (post-2010)
(febuxostat)		Studies
(zileuton)		Trials
(zileuton)		Recent Studies (post-2010) (zileuton)
81813371055164193

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)zileuton (IC50)
Prostaglandin E synthaseHomo sapiens (human)0.6
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)1.4782
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)0.9656
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)0.4
Arachidonate 5-lipoxygenase-activating proteinHomo sapiens (human)0.58
Bifunctional epoxide hydrolase 2Homo sapiens (human)0.591
Polyunsaturated fatty acid 5-lipoxygenaseMus musculus (house mouse)0.19
Leukotriene B4 receptor 1Homo sapiens (human)0.42
Cysteinyl leukotriene receptor 2Homo sapiens (human)0.42
Cysteinyl leukotriene receptor 1Homo sapiens (human)0.42

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Borges, RDS; Brasil, DDSB; Campos, JM; Costa, JDS; Costa, KDSL; Ferreira, EFB; Macêdo, WJDC; Ramos, RDS; Santos, CBRD; Silva, CHTPD1

Reviews

1 review(s) available for febuxostat and zileuton

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for febuxostat and zileuton

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods.
    Molecules (Basel, Switzerland), 2018, Oct-29, Volume: 23, Issue:11

    Topics: Antioxidants; Caffeine; Catalytic Domain; Computer Simulation; Enzymes; Febuxostat; Fluorouracil; Hydroxyurea; Molecular Docking Simulation; Quantum Theory

2018