febuxostat has been researched along with y-700 in 3 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (y-700) | Trials (y-700) | Recent Studies (post-2010) (y-700) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 14 | 0 | 12 |
| Protein | Taxonomy | febuxostat (IC50) | y-700 (IC50) |
|---|---|---|---|
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 0.0058 | |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | 0.0078 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderluh, M; Jakopin, Ž; Kocić, G; Petronijević, Ž; Šmelcerović, A; Šmelcerović, Ž; Tomašič, T; Tomović, K | 1 |
| Chen, H; Li, J; Li, Z; Liu, X; Wu, F; Zhang, L; Zou, Y | 1 |
| Chen, Y; Deng, L; Li, Z; Liu, Y; Nie, L; Xie, R; Xu, X | 1 |
1 review(s) available for febuxostat and y-700
| Article | Year |
|---|---|
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity.
Topics: Allopurinol; Computer Simulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Humans; Molecular Structure; Structure-Activity Relationship; Xanthine Oxidase | 2017 |
2 other study(ies) available for febuxostat and y-700
| Article | Year |
|---|---|
Synthesis and bioevaluation of 1-phenyl-pyrazole-4-carboxylic acid derivatives as potent xanthine oxidoreductase inhibitors.
Topics: Animals; Carboxylic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperuricemia; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Oxonic Acid; Pyrazoles; Structure-Activity Relationship; Xanthine Dehydrogenase | 2017 |
Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors.
Topics: Drug Discovery; Enzyme Inhibitors; Febuxostat; Thiazolidines; Xanthine Oxidase | 2019 |