febuxostat has been researched along with valdecoxib in 2 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (valdecoxib) | Trials (valdecoxib) | Recent Studies (post-2010) (valdecoxib) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 375 | 71 | 86 |
| Protein | Taxonomy | febuxostat (IC50) | valdecoxib (IC50) |
|---|---|---|---|
| Cytochrome c oxidase subunit 2 | Homo sapiens (human) | 1.1 | |
| Carbonic anhydrase 1 | Homo sapiens (human) | 0.1915 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 1.0086 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.927 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.927 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0631 | |
| Carbonic anhydrase 9 | Homo sapiens (human) | 0.027 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.2658 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for febuxostat and valdecoxib
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 other study(ies) available for febuxostat and valdecoxib
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |