Page last updated: 2024-09-04

febuxostat and triazoles

febuxostat has been researched along with triazoles in 23 studies

Compound Research Comparison

Studies
(febuxostat)
Trials
(febuxostat)
Recent Studies (post-2010)
(febuxostat)
Studies
(triazoles)
Trials
(triazoles)
Recent Studies (post-2010) (triazoles)
81813371025,8082,25213,501

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's18 (78.26)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Hussar, DA1
Baumgartner, S; Fleischmann, R; Hingorani, V; Kerr, B; Manhard, K; Miner, JN; Polvent, E; Quart, B; Shen, Z; Suster, M; Yeh, LT1
Edwards, NL; So, A1
Jansen, TL1
Deeks, ED1
Adler, S; Baumgartner, S; Bhakta, N; Dalbeth, N; Fung, M; Jones, G; Khanna, D; Kopicko, J; Perez-Ruiz, F; Storgard, C; Terkeltaub, R1
Hill-McManus, D; Hughes, D; Lane, S; Marshall, S; Soto, E2
Aksenov, S; Eriksson, UG; Peck, CC; Stanski, DR1
Kuehn, BM1
Basile, M; Cicchetti, A; Drago, C; Rolli, FR; Ruggeri, M1
Gillen, M; Hall, J; Ito, Y; Liu, S; Shen, Z; Shiramoto, M; Yamamoto, A; Yan, X1
Jansen, TL; Perez-Ruiz, F; Richette, P; Tausche, AK1
Robinson, PC1
Fields, TR1
Baumgartner, S; Dalbeth, N; Fung, M; Jones, G; Khanna, D; Perez-Ruiz, F; Terkeltaub, R1
Gupta, MK; Singh, JA1
Oyagüez, I; Pérez-Ruiz, F; Presa, M1
Desai, RJ; Kim, E; Kim, SC; Lii, J; Neogi, T1
Borghi, C; Cicero, AFG; Fogacci, F; Kuwabara, M1
Abdel Hakiem, AF; Abdel-Megied, AM; Belal, F; Magdy, G1
Bombardier, C; Edwards, CJ; Pardo Pardo, J; Sriranganathan, MK; Vinik, O1
Cheng, H; Hou, X; Li, X; Nan, G; Ren, L; Tian, J; Xiao, Z; Yan, D; Yang, Y; Ye, F1

Reviews

8 review(s) available for febuxostat and triazoles

ArticleYear
Emerging therapies for gout.
    Rheumatic diseases clinics of North America, 2014, Volume: 40, Issue:2

    Topics: Acetamides; Adrenocorticotropic Hormone; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Benzodiazepines; Febuxostat; Gout; Gout Suppressants; Humans; Imino Furanoses; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Melanocortins; Phenylacetates; Polyethylene Glycols; Pyrimidinones; Recombinant Fusion Proteins; Thiazoles; Thioglycolates; Triazoles; Urate Oxidase; Uricosuric Agents

2014
Lesinurad: A Review in Hyperuricaemia of Gout.
    Drugs & aging, 2017, Volume: 34, Issue:5

    Topics: Adult; Allopurinol; Drug Therapy, Combination; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Kidney; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2017
International position paper on the appropriate use of uricosurics with the introduction of lesinurad.
    Clinical rheumatology, 2018, Volume: 37, Issue:12

    Topics: Benzbromarone; Europe; Febuxostat; Gout; Humans; International Cooperation; Practice Guidelines as Topic; Probenecid; Rheumatology; Thioglycolates; Triazoles; Uricosuric Agents; Xanthine Oxidase

2018
Gout - An update of aetiology, genetics, co-morbidities and management.
    Maturitas, 2018, Volume: 118

    Topics: Allopurinol; Chronic Disease; Comorbidity; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thioglycolates; Triazoles; Uric Acid

2018
The Challenges of Approaching and Managing Gout.
    Rheumatic diseases clinics of North America, 2019, Volume: 45, Issue:1

    Topics: Acetamides; Allopurinol; Antibodies, Monoclonal, Humanized; Colchicine; Diet Therapy; Febuxostat; Gout; Gout Suppressants; Humans; Medication Adherence; Patient Education as Topic; Phenylacetates; Polyethylene Glycols; Quality of Health Care; Rheumatology; Thioglycolates; Triazoles; Urate Oxidase; Uric Acid

2019
Cardiovascular Disease in Gout and the Protective Effect of Treatments Including Urate-Lowering Therapy.
    Drugs, 2019, Volume: 79, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents; Cardiovascular Diseases; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid

2019
Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update.
    Medicina (Kaunas, Lithuania), 2021, Jan-10, Volume: 57, Issue:1

    Topics: Acetamides; Allopurinol; Benzbromarone; Chronic Disease; Evidence-Based Medicine; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Naphthalenes; Nitriles; Phenylacetates; Polyethylene Glycols; Probenecid; Propionates; Pyridines; Thioglycolates; Triazoles; Urate Oxidase; Uricosuric Agents; Xanthine Oxidase

2021
Interventions for tophi in gout.
    The Cochrane database of systematic reviews, 2021, 08-11, Volume: 8

    Topics: Allopurinol; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Randomized Controlled Trials as Topic; Thioglycolates; Triazoles; Urate Oxidase

2021

Trials

4 trial(s) available for febuxostat and triazoles

ArticleYear
Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Adult; Aged; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Thioglycolates; Triazoles; Uric Acid

2014
Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial.
    Arthritis & rheumatology (Hoboken, N.J.), 2017, Volume: 69, Issue:9

    Topics: Creatinine; Double-Blind Method; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid

2017
Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study.
    Rheumatology (Oxford, England), 2018, 09-01, Volume: 57, Issue:9

    Topics: Administration, Oral; Adult; Aged; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Time Factors; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Young Adult

2018
Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study.
    Arthritis research & therapy, 2019, 01-07, Volume: 21, Issue:1

    Topics: Adult; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Thioglycolates; Treatment Outcome; Triazoles; Uricosuric Agents

2019

Other Studies

11 other study(ies) available for febuxostat and triazoles

ArticleYear
New Drugs2010, PART 1.
    Nursing, 2010, Volume: 40, Issue:2

    Topics: Acetamides; Antibodies, Monoclonal; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Azepines; Benzazepines; Benzhydryl Compounds; Benzyl Alcohol; Benzylamines; Cyclams; Cyclopropanes; Drug Combinations; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Ethanolamines; Everolimus; Febuxostat; Fluorenes; Fluoroquinolones; Gout Suppressants; Heterocyclic Compounds; Humans; Immunosuppressive Agents; Indoles; Lacosamide; Milnacipran; Oligopeptides; Phenols; Selective Serotonin Reuptake Inhibitors; Sirolimus; Tapentadol; Thiazoles; Tolvaptan; Triazoles

2010
Treat to target in gout by combining two modes of action.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thiazoles; Thioglycolates; Triazoles

2014
Impact of non-adherence on the safety and efficacy of uric acid-lowering therapies in the treatment of gout.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:1

    Topics: Computer Simulation; Drug Therapy, Combination; Febuxostat; Gout; Gout Suppressants; Humans; Male; Medication Adherence; Models, Biological; Risk Assessment; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid; Xanthine Oxidase

2018
Individualized treatment strategies for hyperuricemia informed by a semi-mechanistic exposure-response model of uric acid dynamics.
    Physiological reports, 2018, Volume: 6, Issue:5

    Topics: Allopurinol; Clinical Trials as Topic; Febuxostat; Humans; Hyperuricemia; Models, Theoretical; Precision Medicine; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents

2018
Chronic Disease Approaches Needed to Curb Gout's Growing Burden.
    JAMA, 2018, Apr-03, Volume: 319, Issue:13

    Topics: Allopurinol; Chronic Disease; Diet; Drug Combinations; Febuxostat; Gout; Gout Suppressants; Healthy Lifestyle; Humans; Patient Education as Topic; Practice Guidelines as Topic; Purines; Thioglycolates; Triazoles; Uric Acid

2018
Cost-Effectiveness Analysis of Lesinurad/Allopurinol Versus Febuxostat for the Management of Gout/Hyperuricemia in Italy.
    PharmacoEconomics, 2018, Volume: 36, Issue:5

    Topics: Allopurinol; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Italy; Male; Markov Chains; Middle Aged; Models, Economic; Monte Carlo Method; Quality-Adjusted Life Years; Thioglycolates; Triazoles

2018
Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2018, Volume: 21, Issue:12

    Topics: Allopurinol; Cohort Studies; Cost-Benefit Analysis; Drug Therapy, Combination; Economics, Pharmaceutical; Febuxostat; Gout; Gout Suppressants; Health Care Costs; Humans; Medication Adherence; Models, Biological; Models, Economic; Quality of Life; Quality-Adjusted Life Years; Thioglycolates; Treatment Outcome; Triazoles; United Kingdom; Uric Acid

2018
Second-line treatment with lesinurad and allopurinol versus febuxostat for management of hyperuricemia: a cost-effectiveness analysis for Spanish patients.
    Clinical rheumatology, 2019, Volume: 38, Issue:12

    Topics: Allopurinol; Cost-Benefit Analysis; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Markov Chains; Spain; Thioglycolates; Triazoles

2019
Trends in Utilization of Urate-Lowering Therapies Following the US Food and Drug Administration's Boxed Warning on Febuxostat.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:3

    Topics: Allopurinol; Cardiovascular Diseases; Cause of Death; Drug Labeling; Febuxostat; Gout; Gout Suppressants; Humans; Mortality; Polyethylene Glycols; Practice Patterns, Physicians'; Probenecid; Risk Factors; Thioglycolates; Triazoles; United States; United States Food and Drug Administration; Urate Oxidase

2021
A novel quality by design approach for development and validation of a green reversed-phase HPLC method with fluorescence detection for the simultaneous determination of lesinurad, febuxostat, and diflunisal: Application to human plasma.
    Journal of separation science, 2021, Volume: 44, Issue:11

    Topics: Chromatography, High Pressure Liquid; Diflunisal; Equipment Design; Febuxostat; Fluorescence; Humans; Software; Tablets; Thioglycolates; Triazoles

2021
Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects.
    Bioorganic chemistry, 2022, Volume: 129

    Topics: Animals; Enzyme Inhibitors; Febuxostat; Gout; Hyperuricemia; Mice; Triazoles; Xanthine Dehydrogenase; Xanthine Oxidase

2022