Compounds > febuxostat
Page last updated: 2024-09-04

febuxostat and tofacitinib

febuxostat has been researched along with tofacitinib in 1 studies

Compound Research Comparison

Studies
(febuxostat)		Trials
(febuxostat)		Recent Studies (post-2010)
(febuxostat)		Studies
(tofacitinib)		Trials
(tofacitinib)		Recent Studies (post-2010) (tofacitinib)
8181337101,6192141,519

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)tofacitinib (IC50)
Chain A, Tyrosine-protein kinaseHomo sapiens (human)0.0117
Chain A, Tyrosine-protein kinaseHomo sapiens (human)0.0117
Chain A, Tyrosine-protein kinase JAK2Homo sapiens (human)0.0117
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)0.0815
Tyrosine-protein kinase JAK2Homo sapiens (human)0.2065
Rho-associated protein kinase 2Homo sapiens (human)3.4
Epidermal growth factor receptorHomo sapiens (human)0.0815
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0815
Tyrosine-protein kinase LckHomo sapiens (human)2.6933
Cytochrome P450 3A4Homo sapiens (human)0.015
Cytochrome P450 2C8Homo sapiens (human)0.0014
Cytochrome P450 2D6Homo sapiens (human)0.0037
Cytochrome P450 2A6Homo sapiens (human)0.012
Tyrosine-protein kinase JAK1Homo sapiens (human)0.0575
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.1411
Cytochrome P450 2C19Homo sapiens (human)0.0016
Tyrosine-protein kinase TecHomo sapiens (human)0.0815
Tyrosine-protein kinase TXKHomo sapiens (human)0.0815
Tyrosine-protein kinase BlkHomo sapiens (human)0.0815
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)0.0815
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0408
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.0006
Tyrosine-protein kinase BTKHomo sapiens (human)0.0815
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)0.0815
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.0815
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.0143
Tyrosine-protein kinase JAK3Mus musculus (house mouse)0.664
Tyrosine-protein kinase JAK2Rattus norvegicus (Norway rat)3.57
Tyrosine-protein kinase JAK3Rattus norvegicus (Norway rat)1.2
Serine/threonine-protein kinase TBK1Homo sapiens (human)5.76

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

1 other study(ies) available for febuxostat and tofacitinib

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013