Compounds > febuxostat
Page last updated: 2024-09-04

febuxostat and terfenadine

febuxostat has been researched along with terfenadine in 1 studies

Compound Research Comparison

Studies
(febuxostat)		Trials
(febuxostat)		Recent Studies (post-2010)
(febuxostat)		Studies
(terfenadine)		Trials
(terfenadine)		Recent Studies (post-2010) (terfenadine)
8181337101,751568346

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)terfenadine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.93
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.231
Epidermal growth factor receptorHomo sapiens (human)3.566
Tyrosine-protein kinase FynHomo sapiens (human)6.123
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.928
ATP-dependent translocase ABCB1Homo sapiens (human)1.8167
Cytochrome P450 3A4Homo sapiens (human)0.32
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.9
D(2) dopamine receptorHomo sapiens (human)6.167
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)0.35
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.34
Alpha-2C adrenergic receptorHomo sapiens (human)3.748
DRattus norvegicus (Norway rat)0.1288
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.1288
Substance-K receptorHomo sapiens (human)2.677
D(1A) dopamine receptorHomo sapiens (human)2.673
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.1288
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.1288
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)2.34
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.928
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.1288
Alpha-1D adrenergic receptorHomo sapiens (human)2.34
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.255
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.231
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.094
Alpha-1A adrenergic receptorHomo sapiens (human)2.34
Histamine H1 receptorHomo sapiens (human)0.0115
Alpha-1B adrenergic receptorHomo sapiens (human)2.34
D(3) dopamine receptorHomo sapiens (human)1.503
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.048
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.34
5-hydroxytryptamine receptor 6Homo sapiens (human)1.306
Cytochrome P450 2J2Homo sapiens (human)8.1
C-C chemokine receptor type 5Homo sapiens (human)1.103
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.93
Sodium-dependent dopamine transporter Homo sapiens (human)0.255
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2233
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.93
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.125
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.971

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

1 other study(ies) available for febuxostat and terfenadine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013