febuxostat has been researched along with rotenone in 2 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (rotenone) | Trials (rotenone) | Recent Studies (post-2010) (rotenone) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 4,407 | 6 | 1,648 |
| Protein | Taxonomy | febuxostat (IC50) | rotenone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 8 | |
| NADH-ubiquinone oxidoreductase chain 1 | Bos taurus (cattle) | 0.015 | |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Bos taurus (cattle) | 0.0051 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 3.6486 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.87 | |
| Acyl carrier protein, mitochondrial | Bos taurus (cattle) | 0.0051 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Honorat, JA; Kinoshita, M; Koda, T; Kumanogoh, A; Mochizuki, H; Nakatsuji, Y; Namba, A; Okuno, T; Sakaguchi, M; Sakoda, S; Sanda, E; Sasaki, T; Shimizu, M; Shirakura, T; Sumi-Akamaru, H; Takata, K; Tamura, M; Yamashita, K | 1 |
2 other study(ies) available for febuxostat and rotenone
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.
Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferase, Mitochondrial; Cell Line; Encephalomyelitis, Autoimmune, Experimental; Energy Metabolism; Febuxostat; Humans; Mice; Mitochondria; Neurons; Oligonucleotide Array Sequence Analysis; Rotenone; Xanthine Oxidase | 2017 |