febuxostat has been researched along with phentolamine in 2 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (phentolamine) | Trials (phentolamine) | Recent Studies (post-2010) (phentolamine) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 9,141 | 270 | 265 |
| Protein | Taxonomy | febuxostat (IC50) | phentolamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.396 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.006 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 10 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0316 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.018 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.11 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0492 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0492 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0492 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0316 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.0173 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.359 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.396 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.0011 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.0108 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 3.807 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0316 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.5495 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
1 review(s) available for febuxostat and phentolamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 other study(ies) available for febuxostat and phentolamine
| Article | Year |
|---|---|
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |