Page last updated: 2024-09-04

febuxostat and montelukast

febuxostat has been researched along with montelukast in 4 studies

Compound Research Comparison

Studies
(febuxostat)
Trials
(febuxostat)
Recent Studies (post-2010)
(febuxostat)
Studies
(montelukast)
Trials
(montelukast)
Recent Studies (post-2010) (montelukast)
8181337101,965598777

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)montelukast (IC50)
Epidermal growth factor receptorHomo sapiens (human)3.197
Tyrosine-protein kinase FynHomo sapiens (human)4.702
Beta-2 adrenergic receptorHomo sapiens (human)3.488
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.689
Alpha-2A adrenergic receptorHomo sapiens (human)3.919
Adenosine receptor A3Homo sapiens (human)0.434
Cytochrome P450 2C8Homo sapiens (human)0.7
Muscarinic acetylcholine receptor M1Homo sapiens (human)8.045
Beta-3 adrenergic receptorHomo sapiens (human)4.3
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.434
Alpha-2C adrenergic receptorHomo sapiens (human)5.279
Muscarinic acetylcholine receptor M3Homo sapiens (human)6.626
Substance-K receptorHomo sapiens (human)3.822
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.689
Thromboxane-A synthase Homo sapiens (human)1.525
D(3) dopamine receptorHomo sapiens (human)7.747
Delta-type opioid receptorHomo sapiens (human)4.795
5-hydroxytryptamine receptor 2BHomo sapiens (human)6.256
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.434
Sodium-dependent dopamine transporter Homo sapiens (human)2.601
Mitogen-activated protein kinase 14Homo sapiens (human)0.856
Leukotriene C4 synthaseHomo sapiens (human)5
Cysteinyl leukotriene receptor 1Homo sapiens (human)0.0015

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Atia, NN; Badary, DM; El-Gizawy, SM; Hareedy, MS; Hosny, NM1
Aslan, C; Evrim Kepekci Tekkeli, S; Gazioglu, I; Kabir, A; Locatelli, M; Tartaglia, A1

Reviews

1 review(s) available for febuxostat and montelukast

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for febuxostat and montelukast

ArticleYear
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Innovative HPTLC method with fluorescence detection for assessment of febuxostat-montelukast combination and study of their protective effects against gouty arthritis.
    The Analyst, 2018, Sep-10, Volume: 143, Issue:18

    Topics: Acetates; Animals; Arthritis, Gouty; Calibration; Chromatography, Thin Layer; Cyclopropanes; Febuxostat; Fluorescence; Humans; Male; Quinolines; Rats; Rats, Wistar; Reproducibility of Results; Sulfides

2018
Simultaneous determination of febuxostat and montelukast in human plasma using fabric phase sorptive extraction and high performance liquid chromatography-fluorimetric detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2022, Jan-01, Volume: 1188

    Topics: Acetates; Adsorption; Adult; Chromatography, High Pressure Liquid; Cotton Fiber; Cyclopropanes; Febuxostat; Humans; Limit of Detection; Linear Models; Quinolines; Reproducibility of Results; Sulfides; Young Adult

2022