febuxostat has been researched along with mirtazapine in 3 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (mirtazapine) | Trials (mirtazapine) | Recent Studies (post-2010) (mirtazapine) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 1,538 | 324 | 646 |
| Protein | Taxonomy | febuxostat (IC50) | mirtazapine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0851 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2239 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.2239 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.1995 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2239 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 3.1623 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2239 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.26 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abu-Risha, SE; Elsisi, AEE; Shalaby, MF; Sokar, SS | 1 |
1 review(s) available for febuxostat and mirtazapine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for febuxostat and mirtazapine
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-κB and MCP1.
Topics: Animals; Anti-Bacterial Agents; Antidepressive Agents; Chemokine CCL2; Drug Synergism; Febuxostat; Gentamicins; Gout Suppressants; Kidney Diseases; Male; Mirtazapine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Rats | 2021 |