febuxostat has been researched along with hypoxanthine in 8 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (hypoxanthine) | Trials (hypoxanthine) | Recent Studies (post-2010) (hypoxanthine) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 2,529 | 65 | 361 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Higashino, K; Hiroishi, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Yamakita, J; Yamamoto, T | 1 |
| Fujimura, Y; Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsui, T; Tsutsumi, Z; Yamamoto, T | 1 |
| Grabowski, BA; Joseph-Ridge, N; Khosravan, R; Vernillet, L; Wu, JT | 1 |
| Joseph-Ridge, N; Khosravan, R; Kukulka, MJ; Vernillet, L; Wu, JT | 1 |
| Iwasaki, H; Kishi, S; Matsuda, Y; Nakamura, T; Ookura, M; Tai, K; Takai, M; Ueda, T; Yamauchi, T; Yoshida, A | 1 |
| Day, RO; Graham, GG; Kamel, B; Kannangara, DR; Williams, KM | 1 |
| Kamatani, N; Kushiyama, A; Toyo-Oka, L; Toyo-Oka, T | 1 |
| Hattori, T; Ito, T; Johnson, TA; Kamatani, N; Kamitsuji, S; Koike, Y; Kume, A; Misu, K; Sobue, G; Watanabe, H | 1 |
1 review(s) available for febuxostat and hypoxanthine
| Article | Year |
|---|---|
Xanthine oxidoreductase and its inhibitors: relevance for gout.
Topics: Allopurinol; Animals; Enzyme Inhibitors; Febuxostat; Gout; Gout Suppressants; Humans; Hypoxanthine; Uric Acid; Xanthine Dehydrogenase | 2016 |
3 trial(s) available for febuxostat and hypoxanthine
| Article | Year |
|---|---|
Pharmacokinetics, pharmacodynamics and safety of febuxostat, a non-purine selective inhibitor of xanthine oxidase, in a dose escalation study in healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Models, Biological; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase | 2006 |
The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Biotransformation; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Protein Binding; Sex Factors; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase; Young Adult | 2008 |
Improved Parkinsons disease motor score in a single-arm open-label trial of febuxostat and inosine.
Topics: Adenosine Triphosphate; Administration, Oral; Aged; Case-Control Studies; Drug Therapy, Combination; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Inosine; Japan; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Safety; Treatment Outcome; Xanthine Dehydrogenase | 2020 |
4 other study(ies) available for febuxostat and hypoxanthine
| Article | Year |
|---|---|
Determination of plasma purine nucleoside phosphorylase activity by high-performance liquid chromatography.
Topics: Adult; Aged; Asthma; Calibration; Chromatography, High Pressure Liquid; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Purine-Nucleoside Phosphorylase; Thiazoles; Uric Acid; Xanthine Oxidase | 1995 |
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
Topics: Allopurinol; Biological Transport; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Febuxostat; Humans; Hypoxanthine; Inosine; Lung Neoplasms; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Pentosyltransferases; Purines; Pyrimidine Phosphorylases; Thiazoles; Tumor Cells, Cultured; Uracil; Uridine; Xanthine; Xanthine Oxidase | 2000 |
Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study.
Topics: Aged; Allopurinol; Antineoplastic Agents; Creatinine; Enzyme Inhibitors; Febuxostat; Female; Glomerular Filtration Rate; Hematologic Neoplasms; Humans; Hypoxanthine; Male; Middle Aged; Pilot Projects; Prospective Studies; Thiazoles; Tumor Lysis Syndrome; Uric Acid; Xanthine; Xanthine Oxidase | 2014 |
Treatment of two mitochondrial disease patients with a combination of febuxostat and inosine that enhances cellular ATP.
Topics: Adenosine Triphosphate; Aged, 80 and over; Cardiomyopathies; Diabetes Mellitus; Febuxostat; Female; Humans; Hypoxanthine; Inosine; Male; Middle Aged; Mitochondria; Mitochondrial Diseases; Natriuretic Peptide, Brain; Reactive Oxygen Species | 2019 |