Compounds > febuxostat
Page last updated: 2024-09-04

febuxostat and dipyridamole

febuxostat has been researched along with dipyridamole in 3 studies

Compound Research Comparison

Studies
(febuxostat)		Trials
(febuxostat)		Recent Studies (post-2010)
(febuxostat)		Studies
(dipyridamole)		Trials
(dipyridamole)		Recent Studies (post-2010) (dipyridamole)
8181337107,826881632

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)dipyridamole (IC50)
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)21.0682
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)21.0682
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1233
Solute carrier family 22 member 2Homo sapiens (human)2.6
Multidrug resistance-associated protein 4Homo sapiens (human)5.15
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.6333
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.9708
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)5.835
Bile salt export pumpHomo sapiens (human)4
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.956
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)2.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.6333
Exopolyphosphatase PRUNE1Homo sapiens (human)0.78
Equilibrative nucleoside transporter 1Homo sapiens (human)0.0537
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6.4

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1

Reviews

2 review(s) available for febuxostat and dipyridamole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Other Studies

1 other study(ies) available for febuxostat and dipyridamole

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013