Page last updated: 2024-09-04

febuxostat and diacerein

febuxostat has been researched along with diacerein in 2 studies

Compound Research Comparison

Studies
(febuxostat)
Trials
(febuxostat)
Recent Studies (post-2010)
(febuxostat)
Studies
(diacerein)
Trials
(diacerein)
Recent Studies (post-2010) (diacerein)
81813371031549157

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)diacerein (IC50)
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)9.234
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)9.234
Female germline-specific tumor suppressor gld-1Caenorhabditis elegans7.308
Multidrug resistance-associated protein 4Homo sapiens (human)6.4
TransthyretinHomo sapiens (human)5.4
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)0.7
N-acylethanolamine-hydrolyzing acid amidaseHomo sapiens (human)0.7
Monoglyceride lipaseHomo sapiens (human)0.7

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Hu, SX; Lei, XM; Shen, GF; Ye, C; Yu, F; Yu, YK; Zhang, ST1

Trials

1 trial(s) available for febuxostat and diacerein

ArticleYear
Combination Therapies of Diacerein and Febuxostat Inhibit IL-1β Responses and Improve Clinical Symptoms in Patients With Refractory Gout.
    American journal of therapeutics, 2017, Volume: 24, Issue:3

    Topics: Adult; Anthraquinones; Anti-Inflammatory Agents; C-Reactive Protein; Case-Control Studies; Drug Therapy, Combination; Etoricoxib; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Interleukin-18; Interleukin-1beta; Male; Middle Aged; Prospective Studies; Pyridines; Sulfones; Treatment Outcome; Uric Acid

2017

Other Studies

1 other study(ies) available for febuxostat and diacerein

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013