febuxostat has been researched along with colchicine in 49 studies
| Studies (febuxostat) | Trials (febuxostat) | Recent Studies (post-2010) (febuxostat) | Studies (colchicine) | Trials (colchicine) | Recent Studies (post-2010) (colchicine) |
|---|---|---|---|---|---|
| 818 | 133 | 710 | 15,472 | 404 | 2,974 |
| Protein | Taxonomy | febuxostat (IC50) | colchicine (IC50) |
|---|---|---|---|
| Tubulin alpha-1A chain | Sus scrofa (pig) | 3.7639 | |
| Tubulin beta chain | Sus scrofa (pig) | 3.8663 | |
| Tubulin beta-4A chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta chain | Homo sapiens (human) | 2.7244 | |
| Tubulin alpha-3C chain | Homo sapiens (human) | 2.4334 | |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | 4.3 | |
| Tubulin alpha-1B chain | Homo sapiens (human) | 2.4334 | |
| Tubulin alpha-4A chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-4B chain | Homo sapiens (human) | 2.4334 | |
| Vesicular acetylcholine transporter | Tetronarce californica (Pacific electric ray) | 2.62 | |
| Tubulin beta-3 chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-2A chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-8 chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-2B chain | Bos taurus (cattle) | 2.8255 | |
| Tubulin alpha-3E chain | Homo sapiens (human) | 2.4334 | |
| Tubulin alpha-1A chain | Homo sapiens (human) | 2.4334 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 3.0611 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 3.1553 | |
| Tubulin alpha-1C chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-6 chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-2B chain | Homo sapiens (human) | 2.4334 | |
| Tubulin beta-1 chain | Homo sapiens (human) | 2.4334 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (6.12) | 29.6817 |
| 2010's | 35 (71.43) | 24.3611 |
| 2020's | 11 (22.45) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Choy, G | 1 |
| Abeles, AM; Pillinger, MH; Rosenthal, P | 1 |
| Lioté, F; Perez-Ruiz, F; Scavulli, J; Terkeltaub, R; Zelman, D | 1 |
| Sundy, JS | 1 |
| Schlesinger, N | 1 |
| Quillen, DM | 1 |
| Graser, E; Pope, RS; Zychowicz, ME | 1 |
| El-Zawawy, H; Mandell, BF | 1 |
| Cohen, MG | 1 |
| Dubost, JJ; Mathieu, S; Soubrier, M | 1 |
| Doghramji, PP | 1 |
| Das, P; Suresh, E | 1 |
| Curiel, RV; Guzman, NJ | 1 |
| Doghramji, PP; Mandell, BF; Pope, RS | 1 |
| Bianchi, G; Borghi, C; Bortoluzzi, A; Cimmino, MA; D'Avola, GM; Desideri, G; Di Giacinto, G; Favero, M; Govoni, M; Grassi, W; Lombardi, A; Manara, M; Marangella, M; Matucci Cerinic, M; Medea, G; Minisola, G; Prevete, I; Punzi, L; Ramonda, R; Scirè, CA; Spadaro, A | 1 |
| Franklin, JM; Kim, SC; Liu, J; Schmidt, BM; Schneeweiss, S; Solomon, DH | 1 |
| Stamp, LK | 2 |
| Baumgartner, S; Fleischmann, R; Hingorani, V; Kerr, B; Manhard, K; Miner, JN; Polvent, E; Quart, B; Shen, Z; Suster, M; Yeh, LT | 1 |
| Bardelli, M; Cantarini, L; Galeazzi, M; Rigante, D; Vitale, A | 1 |
| Mounsey, A; Tillett, J; White, S | 1 |
| Bombardier, C; Buchbinder, R; Edwards, CJ; Kydd, AS; Seth, R | 1 |
| Dalbeth, N; Robinson, PC | 1 |
| Avram, A; Duarte, C; Papagoras, C; Ritis, K; Santos, MJ; Scarpioni, R; Schmidt, WA; Skendros, P | 1 |
| Christensen, HD; Hansen, IM; Morillon, MB; Sheta, HM | 1 |
| Agrawal, A; Saigal, R | 1 |
| Dieudé, P; Forien, M; Ottaviani, S | 1 |
| Aviña-Zubieta, JA; Choi, HK; De Vera, MA; McCormick, N; Rai, SK; Sayre, EC; Shojania, K | 1 |
| Liang, L; Qiu, Q; Xu, H; Yang, X; Yu, J | 1 |
| Fujimori, S; Hidaka, Y; Ide, Y; Inoue, K; Kim, H; Sugimoto, M; Tamaki, S; Taniguchi, A; Yamamoto, T; Yamanaka, H | 1 |
| Lioté, F; Pascart, T | 1 |
| Benarous, K; Serseg, T | 1 |
| Becker, MA; Castillo, M; Gunawardhana, L; Hunt, B; Kisfalvi, K; Saag, KG; Whelton, A | 1 |
| Fields, TR | 1 |
| Chen, JR; Chen, SL; Yang, SW | 1 |
| Cleveland, JD; Singh, JA | 1 |
| Abeles, AM; Bae, SS; Brignardello-Petersen, R; Dalbeth, N; Danve, A; FitzGerald, JD; Gelber, AC; Guyatt, G; Harrold, LR; Khanna, D; Khanna, PP; Kim, SC; King, C; Lenert, A; Levy, G; Libbey, C; Mikuls, T; Mount, D; Neogi, T; Pillinger, MH; Poon, S; Qasim, A; Rosenthal, A; Sehra, ST; Sharma, TSK; Sims, JE; Singh, JA; Smith, BJ; Toprover, M; Turgunbaev, M; Turner, AS; Wenger, NS; Zeng, L; Zhang, MA | 1 |
| Schattner, A | 1 |
| Clebak, KT; Croad, JR; Morrison, A | 1 |
| Bandyopadhyay, D; Deedwania, P; Fonarow, GC; Ghosh, RK; Gupta, M; Hajra, A; Kaul, S; Klein, A; Lavie, CJ; Mamas, M; Roddy, E | 1 |
| Ahn, SM; Hong, S; Kim, YG; Lee, CK; Oh, JS; Yoo, B | 1 |
| Chang, TI; Han, SH; Jhee, JH; Joo, YS; Kang, SW; Kim, HW; Kim, JY; Park, JT; Roh, YH; Yoo, TH; Yun, HR | 1 |
| Bittleman, D; Coras, R; Dadpey, B; Guma, M; Hamilton, B; Lauro, K; Liu-Bryan, R; Mikuls, TR; Quehenberger, O; Reilly, SM; Terkeltaub, R; Thorisdottir, H | 1 |
| Domingues, V; Gorlitsky, B; Guedes, M; Karaboyas, A; LaMoreaux, B; Lew, S; Marder, B; Pecoits-Filho, R; Rivara, MB; Robinson, B; Zhao, J | 1 |
| Chen, H; Chen, L; Ding, R; Hu, X; Jiang, F; Li, X; Li, Y; Liu, K; Peng, Q; Wu, J; Xiong, T; Zhou, Y | 1 |
| Kim, AR; Lee, SG; So, MW | 1 |
22 review(s) available for febuxostat and colchicine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
An update on the treatment options for gout and calcium pyrophosphate deposition.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Chondrocalcinosis; Colchicine; Drug Combinations; Enzyme Inhibitors; Febuxostat; Gout; Gout Suppressants; Humans; Multicenter Studies as Topic; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase | 2005 |
Hyperuricemia and gout: new insights into pathogenesis and treatment.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Interleukin 1 Receptor Antagonist Protein; Thiazoles; Urate Oxidase; Uric Acid | 2007 |
Progress in the pharmacotherapy of gout.
Topics: Allopurinol; Clinical Trials as Topic; Colchicine; Drug Therapy, Combination; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Recombinant Fusion Proteins; Thiazoles; Uricosuric Agents | 2010 |
New agents for the treatment of gout and hyperuricemia: febuxostat, puricase, and beyond.
Topics: Acute Disease; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Polyethylene Glycols; Thiazoles; Urate Oxidase | 2010 |
Crystal arthropathies: recognizing and treating "the gouch".
Topics: Allopurinol; Antimetabolites; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thiazoles; Uric Acid; Uricosuric Agents | 2010 |
Managing gout: how is it different in patients with chronic kidney disease?
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Comorbidity; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Kidney Failure, Chronic; Risk Factors; Thiazoles | 2010 |
[Treatment of gout].
Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Thiazoles; Uric Acid; Uricosuric Agents | 2011 |
Managing your patient with gout: a review of treatment options.
Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Patient Education as Topic; Quality of Life; Risk Factors; Thiazoles | 2011 |
Recent advances in management of gout.
Topics: Adrenal Cortex Hormones; Alcohol Drinking; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Ascorbic Acid; Colchicine; Comorbidity; Cryotherapy; Diet; Dose-Response Relationship, Drug; Febuxostat; Fructose; Gout; Gout Suppressants; Humans; Interleukin 1 Receptor Antagonist Protein; Polyethylene Glycols; Purines; Receptors, Interleukin-1; Recombinant Fusion Proteins; Thiazoles; Urate Oxidase; Uric Acid; Uricosuric Agents; Vitamins; Xanthine Oxidase | 2012 |
Challenges associated with the management of gouty arthritis in patients with chronic kidney disease: a systematic review.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Colchicine; Comorbidity; Contraindications; Febuxostat; Glucocorticoids; Gout Suppressants; Humans; Hyperuricemia; Polyethylene Glycols; Probenecid; PubMed; Renal Insufficiency, Chronic; Secondary Prevention; Thiazoles; Urate Oxidase | 2012 |
Safety profile of anti-gout agents: an update.
Topics: Allopurinol; Colchicine; Drug Interactions; Febuxostat; Gout; Gout Suppressants; HLA-B Antigens; Humans; Interleukin-1; Polyethylene Glycols; Risk Factors; Safety; Thiazoles; Urate Oxidase | 2014 |
Clinical inquiry: Which prophylactic therapies best prevent gout attacks?
Topics: Allopurinol; Colchicine; Evidence-Based Medicine; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Quality of Life; Thiazoles; Urate Oxidase | 2014 |
Allopurinol for chronic gout.
Topics: Allopurinol; Benzbromarone; Chronic Disease; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Probenecid; Randomized Controlled Trials as Topic; Thiazoles; Uric Acid | 2014 |
Advances in pharmacotherapy for the treatment of gout.
Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzbromarone; Clinical Trials, Phase III as Topic; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Polyethylene Glycols; Probenecid; Thiazoles; Urate Oxidase; Uric Acid | 2015 |
Pathogenesis and Clinical Management of Gouty Arthritis.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Gouty; Colchicine; Diet, Healthy; Febuxostat; Fluid Therapy; Gout Suppressants; Humans; Hyperuricemia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Polyethylene Glycols; Smoking Cessation; Urate Oxidase; Uric Acid; Uricosuric Agents; Xanthine Oxidase | 2015 |
Major unanswered questions in the clinical gout field.
Topics: Allopurinol; Benzbromarone; Colchicine; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Patient Care Planning; Probenecid; Renal Insufficiency, Chronic; Uric Acid; Uricosuric Agents | 2017 |
Gout: state of the art after a decade of developments.
Topics: Allopurinol; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Uric Acid; Xanthine Oxidase | 2019 |
The Challenges of Approaching and Managing Gout.
Topics: Acetamides; Allopurinol; Antibodies, Monoclonal, Humanized; Colchicine; Diet Therapy; Febuxostat; Gout; Gout Suppressants; Humans; Medication Adherence; Patient Education as Topic; Phenylacetates; Polyethylene Glycols; Quality of Health Care; Rheumatology; Thioglycolates; Triazoles; Urate Oxidase; Uric Acid | 2019 |
Painless gouty tophus in the nasal bridge: A case report and literature review.
Topics: Aged; Arthritis, Gouty; Biopsy, Fine-Needle; C-Reactive Protein; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Male; Nose; Prevalence; Tomography, X-Ray Computed; Uric Acid | 2019 |
Gout: Rapid Evidence Review.
Topics: Adrenal Cortex Hormones; Allopurinol; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Obesity; Risk Factors; Sex Factors; Uric Acid | 2020 |
Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes.
Topics: Cardiovascular Diseases; Colchicine; COVID-19; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Pandemics | 2021 |
5 trial(s) available for febuxostat and colchicine
| Article | Year |
|---|---|
Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
Topics: Adult; Aged; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Thioglycolates; Triazoles; Uric Acid | 2014 |
Prophylaxis of acute flares when initiating febuxostat for chronic gouty arthritis in a real-world clinical setting.
Topics: Adult; Arthritis, Gouty; Colchicine; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout Suppressants; Humans; Male; Middle Aged; Retrospective Studies | 2018 |
Stepwise dose increase of febuxostat is comparable with colchicine prophylaxis for the prevention of gout flares during the initial phase of urate-lowering therapy: results from FORTUNE-1, a prospective, multicentre randomised study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Dose-Response Relationship, Drug; Febuxostat; Gout; Gout Suppressants; Humans; Incidence; Male; Middle Aged; Prospective Studies; Symptom Flare Up; Uric Acid | 2018 |
Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Colchicine; Cough; Creatinine; Delayed-Action Preparations; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Febuxostat; Female; gamma-Glutamyltransferase; Glomerular Filtration Rate; Gout; Gout Suppressants; Headache; Humans; Hypertension; Male; Middle Aged; Naproxen; Nasopharyngitis; Renal Insufficiency, Chronic; Respiratory Tract Infections; Severity of Illness Index; Treatment Outcome; Uric Acid | 2019 |
A Phase I Study to Evaluate the Pharmacokinetic Drug‒Drug Interaction of HP501, Febuxostat, and Colchicine in Male Chinese Patients with Hyperuricemia.
Topics: Colchicine; East Asian People; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Male; Treatment Outcome; Uric Acid; Uricosuric Agents | 2023 |
22 other study(ies) available for febuxostat and colchicine
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Gout Study Group: update on hyperuricemia and gout.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diet; Europe; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Life Style; Prednisone; Prevalence; Thiazoles; United States; Uric Acid | 2009 |
The current state of care in gout: Addressing the need for better understanding of an ancient disease.
Topics: Acute Disease; Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Rheumatoid; Chronic Disease; Colchicine; Comorbidity; Disease Progression; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Patient Education as Topic; Quality of Life; Risk Factors; Thiazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase | 2010 |
Treatment of gout.
Topics: Aged; Allopurinol; Australia; Colchicine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Febuxostat; Glomerular Filtration Rate; Gout; Gout Suppressants; Humans; Kidney Diseases; Male; Patient Compliance; Practice Guidelines as Topic; Prednisolone; Renal Dialysis; Thiazoles; Uric Acid | 2011 |
Casebook consults: improving outcomes in gout (multimedia activity).
Topics: Adrenal Cortex Hormones; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Long-Term Care; Medication Adherence; Referral and Consultation; Thiazoles; Uric Acid | 2012 |
Italian Society of Rheumatology recommendations for the management of gout.
Topics: Adrenal Cortex Hormones; Advisory Committees; Alcoholic Beverages; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Combined Modality Therapy; Dairy Products; Disease Management; Evidence-Based Medicine; Febuxostat; Female; Fructose; Gout; Humans; Italy; Male; Risk Factors; Smoking; Societies, Medical; Thiazoles; Uric Acid | 2013 |
Clinical and health care use characteristics of patients newly starting allopurinol, febuxostat, and colchicine for the treatment of gout.
Topics: Allopurinol; Ambulatory Care; Colchicine; Comorbidity; Febuxostat; Female; Gout; Gout Suppressants; Hospitalization; Humans; Male; Middle Aged; Office Visits; Thiazoles | 2013 |
Anakinra treatment in patients with gout and type 2 diabetes.
Topics: Aged; Aged, 80 and over; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Blood Glucose; Carbamates; Colchicine; Diabetes Mellitus, Type 2; Febuxostat; Glycated Hemoglobin; Gout; Gout Suppressants; Humans; Hyperuricemia; Hypoglycemic Agents; Insulin; Interleukin 1 Receptor Antagonist Protein; Metformin; Middle Aged; Piperidines; Treatment Outcome; Uric Acid | 2015 |
Identifying Patient Candidates for IL-1 Inhibition: Lessons From Real-World Cases.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Gouty; Chronic Disease; Colchicine; Comorbidity; Febuxostat; Gout Suppressants; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Male; Patient Selection; Prednisolone; Recurrence | 2015 |
Tophaceous Gout in an Anorectic Patient Visualized by Dual Energy Computed Tomography (DECT).
Topics: Absorptiometry, Photon; Allopurinol; Anorexia Nervosa; Biomarkers; Biopsy; Colchicine; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Middle Aged; Patient Compliance; Predictive Value of Tests; Sensitivity and Specificity; Urate Oxidase; Uric Acid | 2016 |
Achilles tendon enthesis with double contour sign revealing gout.
Topics: Achilles Tendon; Arthritis, Gouty; Colchicine; Diagnosis, Differential; Enthesopathy; Febuxostat; Follow-Up Studies; Humans; Male; Middle Aged; Risk Assessment; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography, Doppler | 2017 |
The rising prevalence and incidence of gout in British Columbia, Canada: Population-based trends from 2000 to 2012.
Topics: Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; British Columbia; Colchicine; Comorbidity; Diabetes Mellitus; Febuxostat; Female; Glucocorticoids; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Incidence; Male; Middle Aged; Population Growth; Prevalence; Probenecid; Sulfinpyrazone; Uricosuric Agents | 2017 |
The Inhibitory Effect of Some Drugs on
Topics: Binding, Competitive; Candida; Colchicine; Enzyme Inhibitors; Febuxostat; Folic Acid; Fungal Proteins; Lipase; Molecular Docking Simulation; Protein Binding; Protein Conformation; Structure-Activity Relationship | 2018 |
Hypersensitivity reactions with allopurinol and febuxostat: a study using the Medicare claims data.
Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Colchicine; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Hypersensitivity; Drug Therapy, Combination; Febuxostat; Female; Gout Suppressants; Humans; Incidence; Male; Medicare; Multivariate Analysis; Propensity Score; Proportional Hazards Models; Sex Factors; United States | 2020 |
2020 American College of Rheumatology Guideline for the Management of Gout.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Rheumatology; United States | 2020 |
In older adults, new use of allopurinol or febuxostat was linked to hypersensitivity reactions versus colchicine.
Topics: Aged; Allopurinol; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Medicare; United States | 2020 |
Comparative efficacy of low-dose versus regular-dose colchicine to prevent flares in gout patients initiated on urate-lowering therapies.
Topics: Adult; Aged; Allopurinol; Cohort Studies; Colchicine; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Retrospective Studies; Symptom Flare Up | 2021 |
Colchicine use and the risk of CKD progression: a multicentre nested case-control study.
Topics: Case-Control Studies; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Renal Insufficiency, Chronic; Treatment Outcome; Uric Acid | 2022 |
Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes.
Topics: Adipocytes; Allopurinol; Colchicine; Enzyme Inhibitors; Fatty Acids, Nonesterified; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Inflammation; Lipolysis; Prospective Studies; Uric Acid; Xanthine Oxidase | 2022 |
Gout Prevalence, Practice Patterns, and Associations with Outcomes in North American Dialysis Patients.
Topics: Allopurinol; Colchicine; Febuxostat; Gout; Gout Suppressants; Humans; Male; Prevalence; Quality of Life; Renal Dialysis | 2023 |
Analysis of appropriate duration of colchicine prophylaxis to maximize the persistence of xanthine oxidase inhibitors as the first-line urate-lowering therapy in patients with gout using the Korean Health Insurance Review and Assessment Service database.
Topics: Adult; Allopurinol; Colchicine; Enzyme Inhibitors; Febuxostat; Gout; Gout Suppressants; Humans; Insurance Claim Review; Insurance, Health; Republic of Korea; Retrospective Studies; Uric Acid; Xanthine Oxidase; Young Adult | 2023 |