Page last updated: 2024-09-04

febuxostat and caffeine

febuxostat has been researched along with caffeine in 4 studies

Compound Research Comparison

Studies (febuxostat)	Trials (febuxostat)	Recent Studies (post-2010) (febuxostat)	Studies (caffeine)	Trials (caffeine)	Recent Studies (post-2010) (caffeine)
818	133	710	25,501	2,393	6,825

Protein Interaction Comparison

Protein	Taxonomy	febuxostat (IC50)	caffeine (IC50)
Acetylcholinesterase	Homo sapiens (human)		7.25

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	1 (25.00)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Borges, RDS; Brasil, DDSB; Campos, JM; Costa, JDS; Costa, KDSL; Ferreira, EFB; Macêdo, WJDC; Ramos, RDS; Santos, CBRD; Silva, CHTPD	1

Reviews

2 review(s) available for febuxostat and caffeine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022

Other Studies

2 other study(ies) available for febuxostat and caffeine

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods. Molecules (Basel, Switzerland), 2018, Oct-29, Volume: 23, Issue:11 Topics: Antioxidants; Caffeine; Catalytic Domain; Computer Simulation; Enzymes; Febuxostat; Fluorouracil; Hydroxyurea; Molecular Docking Simulation; Quantum Theory	2018

Article

Year

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013

An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods.

Molecules (Basel, Switzerland), 2018, Oct-29, Volume: 23, Issue:11

Topics: Antioxidants; Caffeine; Catalytic Domain; Computer Simulation; Enzymes; Febuxostat; Fluorouracil; Hydroxyurea; Molecular Docking Simulation; Quantum Theory

2018