Compounds > febuxostat
Page last updated: 2024-09-04

febuxostat and bropirimine

febuxostat has been researched along with bropirimine in 1 studies

Compound Research Comparison

Studies
(febuxostat)		Trials
(febuxostat)		Recent Studies (post-2010)
(febuxostat)		Studies
(bropirimine)		Trials
(bropirimine)		Recent Studies (post-2010) (bropirimine)
8181337101101014

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)bropirimine (IC50)
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
Chain A, Dihydroneopterin aldolaseStaphylococcus aureus38
AlbuminHomo sapiens (human)1
Xanthine dehydrogenase/oxidaseHomo sapiens (human)1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, G; Edfeldt, F; Evenäs, J; Gränse, M; Lepistö, M; Li, C; Li, X; Liao, Y; Lundquist, B; Lv, G; Narjes, F; Rönnholm, A; Svitacheva, N; Synnergren, A; Tjörnebo, A; Varga, M; Wang, J; Wei, M; Wright, J; Yue, S1

Other Studies

1 other study(ies) available for febuxostat and bropirimine

ArticleYear
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase.
    Bioorganic & medicinal chemistry letters, 2014, Mar-01, Volume: 24, Issue:5

    Topics: Animals; Binding Sites; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Gout Suppressants; Half-Life; High-Throughput Screening Assays; Hyperuricemia; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Pyrimidinones; Rats; Structure-Activity Relationship; Xanthine Oxidase

2014