Page last updated: 2024-09-04

febuxostat and acetazolamide

febuxostat has been researched along with acetazolamide in 2 studies

Compound Research Comparison

Studies
(febuxostat)
Trials
(febuxostat)
Recent Studies (post-2010)
(febuxostat)
Studies
(acetazolamide)
Trials
(acetazolamide)
Recent Studies (post-2010) (acetazolamide)
8181337107,6044951,521

Protein Interaction Comparison

ProteinTaxonomyfebuxostat (IC50)acetazolamide (IC50)
Chain A, Class Iii Chitinase Chia1Aspergillus fumigatus A1163164
Carbonic anhydrase 12Homo sapiens (human)0.3178
ReninHomo sapiens (human)8.2
Carbonic anhydrase 1Homo sapiens (human)2.3173
Carbonic anhydrase 2Homo sapiens (human)1.2619
Carbonic anhydrase 2Bos taurus (cattle)0.7
Carbonic anhydrase 3Homo sapiens (human)1.95
Cathepsin BBos taurus (cattle)0.02
Steryl-sulfataseHomo sapiens (human)0.025
Carbonic anhydrase 4Homo sapiens (human)0.1216
Carbonic anhydrase 6Homo sapiens (human)0.2925
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)0.1763
Carbonic anhydrase 7Homo sapiens (human)1.1737
Carbonic anhydrase 9Homo sapiens (human)0.464
ReninMacaca mulatta (Rhesus monkey)8.2
Carbonic anhydrase 13Homo sapiens (human)0.23
Carbonic anhydrase 4Bos taurus (cattle)0.07
Carbonic anhydrase 13Mus musculus (house mouse)0.77
Carbonic anhydrase 14Homo sapiens (human)0.183
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)0.23

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for febuxostat and acetazolamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for febuxostat and acetazolamide

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013