farnesyl-pyrophosphate and cyclopropane

farnesyl-pyrophosphate has been researched along with cyclopropane* in 1 studies

Other Studies

1 other study(ies) available for farnesyl-pyrophosphate and cyclopropane

Article	Year
Modes of inactivation of trichodiene synthase by a cyclopropane-containing farnesyldiphosphate analog. Organic & biomolecular chemistry, 2009, Oct-07, Volume: 7, Issue:19 We describe quantum chemical calculations on the rearrangement of carbocations derived from a cyclopropane-containing analog of farnesyl diphosphate (FPP). These calculations reveal significant differences between the energetics for rearrangement of this analog and FPP itself, suggesting that the behavior of this substrate analog likely does not mirror that of the natural substrate. In addition, our results point to new mechanisms by which this FPP analog inactivates trichodiene synthase. Topics: Carbon-Carbon Lyases; Cyclopropanes; Enzyme Activation; Models, Molecular; Molecular Conformation; Polyisoprenyl Phosphates; Protons; Quantum Theory; Sesquiterpenes	2009

Article

Year

Modes of inactivation of trichodiene synthase by a cyclopropane-containing farnesyldiphosphate analog.

Organic & biomolecular chemistry, 2009, Oct-07, Volume: 7, Issue:19

We describe quantum chemical calculations on the rearrangement of carbocations derived from a cyclopropane-containing analog of farnesyl diphosphate (FPP). These calculations reveal significant differences between the energetics for rearrangement of this analog and FPP itself, suggesting that the behavior of this substrate analog likely does not mirror that of the natural substrate. In addition, our results point to new mechanisms by which this FPP analog inactivates trichodiene synthase.

Topics: Carbon-Carbon Lyases; Cyclopropanes; Enzyme Activation; Models, Molecular; Molecular Conformation; Polyisoprenyl Phosphates; Protons; Quantum Theory; Sesquiterpenes

2009