farnesol has been researched along with lovastatin in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.00) | 18.7374 |
| 1990's | 28 (70.00) | 18.2507 |
| 2000's | 10 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bradfute, DL; Silva, CJ; Simoni, RD | 1 |
| Denham, KS; Lutz, RJ; Sinensky, M; Trujillo, MA; Wenger, L | 1 |
| Bourne, JR; Buss, JE; Cochrane, CG; Der, CJ; Jackson, JH; Solski, PA | 1 |
| Bennett, JL; Chen, GZ; Foster, LA; Mills, G; Vandewaa, EA | 1 |
| Farnsworth, DE; Feyereisen, R | 1 |
| Bernini, F; Corsini, A; Fumagalli, R; Paoletti, R; Raiteri, M; Soma, MR | 1 |
| Betteridge, L; Chan, P; Clunn, G; Gallagher, K; Hughes, A; Munro, E; Patel, M; Schachter, M; Sever, P; Wolfe, J | 1 |
| Blazejewski, S; Dhumeaux, D; Mallat, A; Mavier, P; Preaux, AM; Rosenbaum, J | 1 |
| Corsini, A; Fumagalli, R; Gabbiani, G; Mazzotti, M; Paoletti, R; Raiteri, M; Soma, MR | 1 |
| Atluru, D; Kasiske, BL; Keane, WF; Kim, Y; O'Donnell, MP | 1 |
| Crick, DC; Feller, DR; Henry, KW; Noonan, DJ; O'Brien, ML; Rangwala, SM; Waechter, CJ; Weinberger, C | 1 |
| Chambers, C; Keller, RK; Ness, GC; Zhao, Z | 1 |
| Andres, DA; Crick, DC; Waechter, CJ | 1 |
| Nakata, H; Nishio, E; Tomiyama, K; Watanabe, Y | 1 |
| Kanayama, Y; Negoro, N; Okamura, M; Takeda, T; Umetani, N | 1 |
| Hamilton, AD; McGuire, TF; Qian, Y; Sebti, SM; Vogt, A | 2 |
| Carel, K; Draznin, B; Heidenreich, KA; Kummer, JL; Leitner, W; Schubert, C | 1 |
| Durham, SK; Flint, OP; Gregg, RE; Masters, BA | 1 |
| Blazer-Yost, BL; Hughes, CL; Nolan, PL | 1 |
| Ghidoni, JJ; Ghosh, PM; Ghosh-Choudhury, N; Kreisberg, JI; Mott, GE; Radnik, RA; Stapleton, ML | 1 |
| Braquet, P; Cousse, H; Mencia-Huerta, JM; Paubert-Braquet, M; Raynaud, JP | 1 |
| Bitterman, P; Greatens, T; Kratzke, RA; Polunovsky, VA; Rubins, JB; Tan, AT | 1 |
| Andres, DA; Crick, DC; Danesi, R; Macchia, M; Waechter, CJ | 1 |
| Kanda, Y; Nishio, E; Watanabe, Y | 1 |
| Croucher, PI; Helfrich, MH; Rogers, MJ; Russell, RG; Shipman, CM | 1 |
| Fisher, JE; Halasy, JM; Hughes, DE; Luckman, SP; Masarachia, PJ; Reszka, AA; Rodan, GA; Rogers, MJ; Russell, RG; Wesolowski, G | 1 |
| Aloj, SM; Bifulco, M; Laezza, C | 1 |
| Foster, BA; Ghosh, PM; Ghosh-Choudhury, N; Greenberg, NM; Kreisberg, JI; Mott, GE; Moyer, ML; Thomas, CA | 1 |
| Fawcett, TW; Gorospe, M; Holbrook, NJ; Hudgins, WR; Shack, S | 1 |
| Bach, TJ; Hemmerlin, A | 1 |
| Cheng, QF; Rao, PV; Zigler, JS | 1 |
| Blasig, IE; Ferdinandy, P; Horvath, P; Lonovics, J; Nagy, I; Nemeth, J; Porszasz, R; Sari, R; Szilvassy, Z | 1 |
| Hohl, RJ; Ownby, SE | 2 |
| Buurman, SW; Frenkel, J; Houten, SM; Kuis, W; Mandey, SH; Rijkers, GT; Wanders, RJ; Waterham, HR | 1 |
| Csonka, C; Csont, T; Ferdinandy, P; Giricz, Z; Onody, A | 1 |
| Jung, M; McAnally, JA; Mo, H | 1 |
| DomÃnguez, A; Ruiz-Velasco, N; Vega, MA | 1 |
| Deng, Y; DeRose, RA; Farber, SA; Ho, SY; Santana, E; Thorpe, JL | 1 |
40 other study(ies) available for farnesol and lovastatin
| Article | Year |
|---|---|
Squalene synthase-deficient mutant of Chinese hamster ovary cells.
Topics: Acetates; Animals; CHO Cells; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cricetinae; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Flow Cytometry; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mevalonic Acid; Mutagenesis | 1992 |
Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear lamina.
Topics: Animals; Cell Compartmentation; Cell Nucleus; CHO Cells; Cricetinae; Farnesol; Lamin Type A; Lamins; Lovastatin; Nuclear Envelope; Nuclear Proteins; Protein Precursors; Protein Processing, Post-Translational; Recombinant Proteins; Structure-Activity Relationship | 1992 |
Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation.
Topics: Animals; Anticholesteremic Agents; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Exons; Farnesol; Genetic Vectors; Humans; Lovastatin; Mevalonic Acid; Mice; Mutation; Oligonucleotide Probes; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Transfection | 1990 |
Physiological role of HMG-CoA reductase in regulating egg production by Schistosoma mansoni.
Topics: Animals; Dose-Response Relationship, Drug; Farnesol; Female; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lovastatin; Mice; Ovum; Schistosoma mansoni; Tissue Distribution | 1989 |
Characterization and regulation of HMG-CoA reductase during a cycle of juvenile hormone synthesis.
Topics: Animals; Cockroaches; Corpora Allata; Cycloheximide; Enzyme Activation; Farnesol; Female; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kinetics; Lovastatin; Mevalonic Acid; Microsomes; Sesquiterpenes; Stereoisomerism | 1987 |
Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cell Division; Cell Movement; Cells, Cultured; Cholesterol Esters; Diterpenes; Farnesol; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Macrophages, Peritoneal; Male; Mevalonic Acid; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Pravastatin; Rabbits; Rats; Rats, Sprague-Dawley; Simvastatin | 1995 |
Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis.
Topics: Adenine; Cell Division; Cells, Cultured; Cholesterol; Coronary Disease; Farnesol; Humans; Isopentenyladenosine; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Saphenous Vein | 1994 |
Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme A reductase, on the growth of human Ito cells.
Topics: Actins; Adenine; Analysis of Variance; Autoradiography; Cell Division; Cells, Cultured; Cholesterol, LDL; Desmin; DNA; Farnesol; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isopentenyladenosine; Liver; Lovastatin; Mevalonic Acid; Simvastatin | 1994 |
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase.
Topics: Acyclic Monoterpenes; Animals; Aorta; Cell Division; Cells, Cultured; Cholesterol; Diterpenes; Dose-Response Relationship, Drug; Farnesol; Fatty Acids, Monounsaturated; Femoral Artery; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Squalene; Terpenes | 1993 |
Lovastatin inhibits proliferation of rat mesangial cells.
Topics: Adenine; Animals; Cell Division; Cells, Cultured; DNA; DNA Replication; Dose-Response Relationship, Drug; Farnesol; Glomerular Mesangium; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isopentenyladenosine; Kinetics; Lovastatin; Mevalonic Acid; Rats; Thymidine | 1993 |
Convergence of three steroid receptor pathways in the mediation of nongenotoxic hepatocarcinogenesis.
Topics: Acyl-CoA Oxidase; Animals; Anticholesteremic Agents; Cholesterol; Farnesol; Fatty Acids, Unsaturated; Liver Neoplasms; Lovastatin; Microbodies; Oxidoreductases; Polyisoprenyl Phosphates; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Sesquiterpenes; Transcription Factors | 1996 |
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.
Topics: Animals; Anticholesteremic Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Cycloheximide; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Half-Life; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Liver; Lovastatin; Male; Mevalonic Acid; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Time Factors; Tricarboxylic Acids | 1996 |
Geranylgeraniol restores cell proliferation to lovastatin treated C6 glial cells.
Topics: Animals; Cell Division; Cell Line; Diterpenes; Enzyme Inhibitors; Farnesol; Haplorhini; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Lovastatin; Neuroglia; Rats | 1996 |
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor impairs cell p4fferentiation in cultured adipogenic cells (3T3-L1).
Topics: 3T3 Cells; Acyclic Monoterpenes; Animals; Azo Compounds; Cell Differentiation; Cholesterol; Enzyme Inhibitors; Farnesol; Glycerolphosphate Dehydrogenase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lovastatin; Mevalonic Acid; Mice; Terpenes | 1996 |
Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages.
Topics: Cell Line; Dactinomycin; Enzyme Inhibitors; Farnesol; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Macrophages; Membrane Proteins; Mevalonic Acid; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate | 1996 |
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyltranstransferase; Kinetics; Lovastatin; Methionine; Mice; Phosphorylation; Phosphotyrosine; Protein Prenylation; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Structure-Activity Relationship; Transfection; Transferases | 1996 |
Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Benzamides; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Diterpenes; DNA; Enzyme Inhibitors; Farnesol; Fibroblasts; G1 Phase; Genes, ras; GTP-Binding Proteins; Lovastatin; Methionine; Mevalonic Acid; Mice; Protein Prenylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; rap GTP-Binding Proteins; ras Proteins; Resting Phase, Cell Cycle; S Phase; Transferases | 1996 |
Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes.
Topics: Adipocytes; Alkyl and Aryl Transferases; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Farnesol; Farnesyltranstransferase; Guanosine Triphosphate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Lovastatin; Mice; Organophosphonates; Organophosphorus Compounds; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Signal Transduction; Transferases | 1996 |
Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticholesteremic Agents; Butylamines; Cells, Cultured; Cholesterol; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Muscle, Skeletal; Pravastatin; Pregnancy; Prodrugs; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Squalene; Sulfonic Acids | 1997 |
Protein prenylation is required for aldosterone-stimulated Na+ transport.
Topics: Acetylcysteine; Aldosterone; Animals; Biological Transport; Cell Line; Cysteine; Dimethylallyltranstransferase; Diterpenes; Enzyme Inhibitors; Epithelium; Farnesol; Insulin; Kidney; Kinetics; Lovastatin; Organophosphonates; Protein Prenylation; Sodium | 1997 |
Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells.
Topics: Actins; Animals; Apoptosis; Bromodeoxyuridine; Cell Count; Cell Division; Cell Movement; Cell Size; Cells, Cultured; Diterpenes; Farnesol; Glomerular Mesangium; GTP-Binding Proteins; Lovastatin; Microscopy, Electron; Microscopy, Video; Mitosis; Protein Prenylation; Rats; rhoA GTP-Binding Protein | 1997 |
Effect of the lipidosterolic extract of Serenoa repens (Permixon) and its major components on basic fibroblast growth factor-induced proliferation of cultures of human prostate biopsies.
Topics: Acyclic Monoterpenes; Androgen Antagonists; Cell Division; Cells, Cultured; Epidermal Growth Factor; Farnesol; Fibroblast Growth Factor 2; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Plant Extracts; Prostate; Prostatic Hyperplasia; Serenoa; Terpenes | 1998 |
Lovastatin induces apoptosis in malignant mesothelioma cells.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line; Cell Membrane; Cell Survival; Cytosol; DNA, Neoplasm; Dose-Response Relationship, Drug; Farnesol; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mesothelioma; Mevalonic Acid; Protein Prenylation; ras Proteins; Tumor Cells, Cultured | 1998 |
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells.
Topics: Animals; Cell Division; Diterpenes; Electrophoresis, Polyacrylamide Gel; Farnesol; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Molecular Weight; Nerve Tissue Proteins; Polyisoprenyl Phosphates; Protein Prenylation; Rats; Thymidine; Tumor Cells, Cultured | 1998 |
Alpha1-adrenoreceptor stimulation causes vascular smooth muscle cell hypertrophy: a possible role for isoprenoid intermediates.
Topics: Adrenergic alpha-Agonists; Animals; Anticholesteremic Agents; Aorta, Thoracic; Carbon Radioisotopes; Cell Count; Cells, Cultured; Cholesterol; Drug Interactions; Farnesol; Hypertrophy; Leucine; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Phenylephrine; Protein Prenylation; Rats; Receptors, Adrenergic, alpha-1; Transferases | 1998 |
The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Lovastatin; Mevalonic Acid; Multiple Myeloma; Protein Prenylation; Tumor Cells, Cultured | 1998 |
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro.
Topics: Alendronate; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Cholesterol; Clodronic Acid; Diterpenes; Enzyme Activation; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Osteoclasts; Protein Kinases; Rabbits; Skull; Squalene | 1999 |
Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells.
Topics: Animals; Cattle; Cell Differentiation; Cell Division; Cell Line; DNA; Farnesol; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Protein Prenylation; Rats; Thyroid Gland; Thyrotropin | 1999 |
Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line.
Topics: Actin Cytoskeleton; Adenocarcinoma; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Division; Cell Size; Diterpenes; Drug Interactions; Enzyme Activation; Farnesol; G1 Phase; Genes, ras; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Mice; Mice, Transgenic; Polyisoprenyl Phosphates; Prostatic Neoplasms; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Sesquiterpenes; Tumor Cells, Cultured | 1999 |
Activation of the cholesterol pathway and Ras maturation in response to stress.
Topics: Adenocarcinoma; Calcium-Calmodulin-Dependent Protein Kinases; Cholesterol; Diterpenes; Farnesol; Genes, ras; Heat-Shock Response; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Lovastatin; Male; Mevalonic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Prenylation; ras Proteins; Sterols; Stress, Physiological | 1999 |
Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells.
Topics: Blotting, Northern; Blotting, Western; Cell Death; Cell Division; Cell Size; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Farnesol; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Nicotiana; Plants, Toxic; RNA, Messenger | 2000 |
Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cataract; Cyclohexenes; Diterpenes; Dose-Response Relationship, Drug; Farnesol; Female; GTP Phosphohydrolases; Lens, Crystalline; Lovastatin; Male; Monoterpenes; Organ Culture Techniques; Protein Prenylation; Rats; Rats, Sprague-Dawley; Terpenes | 2001 |
Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi.
Topics: Animals; Anticholesteremic Agents; Calcitonin Gene-Related Peptide; Cholesterol; Cyclic AMP; Cyclic GMP; Electric Stimulation; Farnesol; GTP-Binding Protein alpha Subunits, Gs; In Vitro Techniques; Lovastatin; Male; Membranes; Muscle Relaxation; Neurotransmitter Agents; Nitric Oxide; Rabbits; Sphincter of Oddi; Vasoactive Intestinal Peptide | 2001 |
Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells.
Topics: 3T3 Cells; Animals; Anticholesteremic Agents; Diterpenes; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Protein Prenylation | 2002 |
Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.
Topics: Antibodies; CD2 Antigens; CD28 Antigens; Cell Division; Cells, Cultured; Child; Diterpenes; Familial Mediterranean Fever; Farnesol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypergammaglobulinemia; Immunoglobulin D; Interleukin-1; Lovastatin; Male; Mevalonic Acid; Phosphotransferases (Alcohol Group Acceptor); Polyisoprenyl Phosphates; T-Lymphocytes | 2002 |
Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis.
Topics: Animals; Blotting, Western; Cholesterol, Dietary; Electron Spin Resonance Spectroscopy; Farnesol; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lovastatin; Male; Mevalonic Acid; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Superoxides | 2003 |
Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis.
Topics: Alcohols; Animals; Cycloheximide; Diterpenes; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lovastatin; Mice; Monomeric GTP-Binding Proteins; NIH 3T3 Cells; Protein Biosynthesis; Protein Prenylation; Protein Synthesis Inhibitors; ras Proteins; Terpenes | 2003 |
Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caco-2 Cells; Cell Cycle; Cell Division; Dose-Response Relationship, Drug; Farnesol; HL-60 Cells; Humans; Hydroquinones; In Vitro Techniques; Lovastatin; Mice; Terpenes; Time Factors | 2003 |
Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression.
Topics: Actins; Anticholesteremic Agents; CD36 Antigens; Cells, Cultured; Cytoskeleton; Diterpenes; Farnesol; Gene Expression Regulation; Humans; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Monocytes; Receptors, Cytoplasmic and Nuclear; rho GTP-Binding Proteins; RNA, Messenger; Transcription Factors; Transcription, Genetic | 2004 |
Lipid metabolism in zebrafish.
Topics: 4-Chloro-7-nitrobenzofurazan; Alkyl and Aryl Transferases; Animals; Annexin A2; Atorvastatin; Azetidines; Boron Compounds; Caveolin 1; Caveolins; Cell Movement; Cholesterol; Diterpenes; DNA; Embryo, Nonmammalian; Ethylnitrosourea; Ezetimibe; Farnesol; Farnesyltranstransferase; Geranyltranstransferase; Germ Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Lovastatin; Mevalonic Acid; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Phosphatidylethanolamines; Protein Binding; Protein Prenylation; Pyrroles; Simvastatin; Zebrafish | 2004 |